Yi-Ning Wu

Yi-Ning Wu
University of Massachusetts Lowell | UML · Department of Physical Therapy

PhD

About

48
Publications
7,739
Reads
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871
Citations
Citations since 2017
15 Research Items
512 Citations
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
2017201820192020202120222023020406080100
Additional affiliations
September 2013 - present
University of Massachusetts Lowell
Position
  • Professor (Assistant)

Publications

Publications (48)
Article
Full-text available
The generation of isometric force at the hand can be mediated by activating a few motor modules. Stroke induces alterations in motor modules underlying steady-state isometric force generation in the human upper extremity (UE). However, how the altered motor modules impact task performance (force production) remains unclear as stroke survivors devel...
Article
Full-text available
Soldiers working in the field of explosive ordnance disposal (EOD) wear cumbersome personal protective equipment (PPE) that may affect their performance in the field, limit their mobility, and cause discomfort. The objective of this study was to develop a test methodology to identify the relationship between EOD suit interface loads and mission-cri...
Article
The purpose of this study was to develop quantitative parameters using range of motion (ROM) of shanks, thighs and knees to evaluate the effect of deep brain stimulation (DBS) on gait performance and freezing of gait (FOG) of patients with advanced Parkinson’s disease (PD). Three patients with FOG due to Parkinson’s disease advanced who has receive...
Article
Objective To provide a comprehensive characterization of explosive ordnance disposal (EOD) personal protective equipment (PPE) by evaluating its effects on the human body, specifically the poses, tasks, and conditions under which EOD operations are performed. Background EOD PPE is designed to protect technicians from a blast. The required features...
Article
This study is to examine the effects of a 12-session moderate intensity-interval-training program with blood flow restriction (BFR) and body cooling (BC) on people who have had persistent post-concussive symptoms (PPCS) for <1 year. A single-blind randomized controlled trial of interval-training exercise with BFR and BC was conducted. Twenty-five a...
Article
Aim: To assess the neural and non-neural contributions to spasticity in the impaired ankle of children with cerebral palsy (CP). Method: Instrumented tapping of the Achilles tendon was done isometrically to minimize non-neural contributions and elicit neural contributions. Robot-controlled ankle stretching was done at various velocities, includi...
Article
Recent research has shown that exercise can improve post-concussion symptoms. It might be because exercise-induced human growth hormone enhances the brain function and recovery. Exercise under blood flow restriction (BFR) and cooling triggers physiologic responses at a relatively low intensity that might be beneficial to individuals with PCS and re...
Article
Full-text available
[Purpose] To examine muscular demands during self-propelled treadmill walking to provide a potential option for fitness training. [Participants and Methods] Eleven healthy college students were recruited. Participants walked under three conditions: over-ground walking at a self-selected speed, treadmill walking at a self-selected speed, and treadmi...
Article
Full-text available
We investigated the muscle alterations related to spasticity in stroke quantitatively using a portable manual spasticity evaluator. Methods: Quantitative neuro-mechanical evaluations under controlled passive elbow stretches in stroke survivors and healthy controls were performed in a research laboratory of a rehabilitation hospital. Twelve stroke s...
Conference Paper
In this paper, Granger causality (GC) and New causality (NC) analysis methods are applied in frequency domain to reveal causality changes from non-fatigue state to fatigue state with EEG signals during video game-playing. EEG signals were recorded while a subject was playing video-games. Results show that fatiguing phenomenon was observed in 15 sub...
Article
This paper presents the iterative development of an artificially intelligent system to promote home-based neurorehabilitation. Although proper, structured practice of rehabilitation exercises at home is the key to successful recovery of motor functions, there is no home-program out there which can monitor a patient's exercise-related activities and...
Article
Study Design Controlled laboratory study. Background Recurrent ankle sprains associated with chronic ankle instability (CAI) occur not only in challenging sports but also in daily walking. Understanding whether and how CAI alters feedback and feedforward controls during walking may be important for developing interventions for CAI prevention or tre...
Article
Muscle fiber tension and sarcomere length play critical roles in regulating muscle functions and adaptations under pathological conditions. However, methods are lacking to quantify these two variables simultaneously in vivo. A novel force microscope was developed with the unique capabilities of estimating muscle fiber tension and acquiring sarcomer...
Article
Objective: To examine the outcomes of a home-based robotic rehabilitation and compare it to a laboratory-based robotic rehabilitation for the treatment of impaired ankles in children with cerebral palsy DESIGN: A randomized comparative trial design comparing a home-based training group and a laboratory-based training group. Setting: Home versus...
Article
Ankle movement training is important in motor recovery post stroke and early intervention is critical to stroke rehabilitation. However, acute stroke survivors receive motor rehabilitation in only a small fraction of time, partly due to the lack of effective devices and protocols suitable for early in-bed rehabilitation. Considering the first few m...
Article
Full-text available
[Purpose] This study was performed to examine the relationship between physical performance and muscle properties during police cadet training. The study's hypothesis was that improved physical performance brought about by training, would in turn cause a reduction in muscle flexibility. [Subjects and Methods] Fifty-nine police cadets were included...
Article
Arm impairments in patients post stroke involve the shoulder, elbow and wrist simultaneously. It is not very clear how patients develop spasticity and reduced range of motion (ROM) at the multiple joints and the abnormal couplings among the multiple joints and the multiple degrees-of-freedom (DOF) during passive movement. It is also not clear how t...
Chapter
The objective of this paper is to introduce a novel low-cost humancomputer interface (HCI) system for home-based massed practice for children with cerebral palsy (CP). Successful massed practice, a type of neurorehabilitation, may be of value for children with CP because it facilitates impaired hand use. Use of automated, home-based systems could p...
Article
The pattern of antenatal brain injury varies with gestational age at the time of insult. Deep brain nuclei are often injured at older gestational ages. Having previously shown postnatal hypertonia after preterm fetal rabbit hypoxia-ischemia, the objective of this study was to investigate the causal relationship between the dynamic regional pattern...
Article
Massed practice may be of value for children with cerebral palsy (CP) as a means to promote functional recovery. Use of automated and home-based systems could provide a practical means for ongoing rehabilitation therapy. However, the appropriate way to deliver, structure, and monitor massed practice in the home setting in order to maximize neural a...
Article
Full-text available
Biomechanical properties of calf muscles and Achilles tendon may be altered considerably in children with cerebral palsy (CP), contributing to childhood disability. It is unclear how muscle fascicles and tendon respond to rehabilitation and contribute to improvement of ankle-joint properties. Biomechanical properties of the calf muscle fascicles of...
Article
Full-text available
Spasticity and contracture are major sources of disability in people with neurological impairments that have been evaluated using various instruments: the Modified Ashworth Scale, tendon reflex scale, pendulum test, mechanical perturbations, and passive joint range of motion (ROM). These measures generally are either convenient to use in clinics bu...
Article
Full-text available
Ankle impairments are closely associated with functional limitations in children with cerebral palsy (CP). Passive stretching is often used to increase the range of motion (ROM) of the impaired ankle. Improving motor control is also a focus of physical therapy. However, convenient and effective ways to control passive stretching and motivate active...
Article
The biomechanical effects of placing a portal through the subscapularis tendon have not been studied. Our hypothesis is that placing a portal through the subscapularis tendon will affect the strain properties of the tendon. Eight shoulders from deceased donors were dissected to expose the subscapularis musculotendinous unit. The subscapularis muscl...
Article
The current study introduces a novel rehabilitation robot for treatment of impaired ankle in children with cerebral palsy (CP). The treatment consisted of passive stretching under intelligent control and active movement training with motivating game-playing using the portable robot. After 18 sessions of training (3 sessions/week for 6 weeks), we fo...
Article
Current work demonstrates a new method and a new device for simultaneous in vivo measurements of sarcomere imaging and fiber tension. Sarcomere, a building block of muscles, plays a critical role in muscle contraction. In the pathological conditions, the biomechanical properties of sarcomere and muscle fibers may be altered significantly. We develo...
Article
To evaluate spasticity under controlled velocities and torques in children with cerebral palsy (CP) using a manual spasticity evaluator. The study involved 10 children with spastic CP (six males, four females; mean age 10 y 1 mo, SD 2 y 9 mo, range 7-16 y; one with quadriplegia, six with right hemiplegia, three with left hemiplegia; Gross Motor Fun...
Article
Progressive changes in the muscle tone and stretch reflex after spinal cord injury (SCI) provide insight into the time-course development of spasticity. This study quantified the time-course changes of hypertonia for rats following SCI of T8 hemisection. A miniature manual stretching device measured the reactive torque via a pair of pressure sensin...
Article
Full-text available
A portable ankle rehabilitation robot with intelligent stretching and game-based active movement training was used to treat the spastic impaired ankle of children with cerebral palsy over six weeks. The subject's calf muscles and Achilles tendon properties were evaluated before and after treatment using ultrasonography and biomechanical measures. I...
Article
Adenosine A2A receptor agonists produce a hypokinetic state (catalepsy) that is believed to reflect antagonistic interaction of A2A and dopamine D2 receptors in the basal ganglia. In addition to catalepsy, pharmacological blockade of D2 receptors produces rigidity. However there are conflicting data about the effect of A2A agonists on muscle tone,...
Article
Full-text available
Spasticity, contracture, and muscle weakness are commonly observed poststroke in muscles crossing the ankle. However, it is not clear how biomechanical properties of the Achilles tendon change poststroke, which may affect functions of the impaired muscles directly. Biomechanical properties of the Achilles tendon, including the length and cross-sect...
Article
To quantify changes of elbow spasticity over time after botulinum toxin type A (BTX-A) injection in the upper extremity of stroke patients. Before-after trial in which the therapeutic effects were followed up at 2, 6, and 9 weeks after the BTX-A injection (Botox). Hospital. Chronic stroke patients (N=8) with upper-limb spasticity. BTX-A was injecte...
Article
Anterior cruciate ligament (ACL) is the most commonly injured knee ligament in sports-related activities, especially in pivoting sports. In general, knee joint movements about the off-axes are much more limited and musculoskeletal injuries are usually associated with excessive loading/movement about the off-axes. The purposes of this project were t...
Conference Paper
A portable tele-assessment system was designed for remote evaluation of the elbow joint with spasticity and contracture in patients with neurological disorders. A master device and a slave device were used to drive a manikin arm and the patient's arm, respectively. The elbow flexion angle and torque were measured at both the master and slave device...
Article
Rodent models of Parkinson's disease (PD) are usually assessed using measures of akinesia, but other important parkinsonian symptoms such as rigidity are only rarely quantified. This is in part due to technical difficulties in obtaining such measures in small animals. In the present study we developed quantitative methods to provide time-course ass...
Article
Full-text available
Spasticity is often seen in patients with central nervous system lesion, such as stroke. It hinders functional movement and may induce pain. Current measures for assessing Spasticity are either quantitative but not convenient to use or convenient to use in clinics but lack of objective quantification. We developed a manual spasticity evaluator (MSE...
Article
To use a portable muscle tone assessment device to measure spasticity after a botulinum toxin type A (BTX-A) injection. Before-after trial. Hospital. Ten chronic stroke patients with upper-limb spasticity. BTX-A was injected in the biceps brachii. The biomechanic parameters, viscous component, and averaged viscosity derived from the acquired reacti...
Article
Full-text available
The aim of this study is to utilize the portable muscle tone measurement device and surface EMG for investigating the spasticity on the elbow flexors before BOTOX ® intervention. The reactive torque and reactive EMG (biceps brachii and triceps brachii muscles) of elbow joint induced at different stretching velocities (1/3, 1/2, 1 and 1.5 Hz) in lim...

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