Yi Ning Johanna Strube

Yi Ning Johanna Strube
Queen's University | QueensU · Department of Ophthalmology

Doctor of Medicine

About

58
Publications
2,087
Reads
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326
Citations
Citations since 2016
21 Research Items
164 Citations
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530
2016201720182019202020212022051015202530

Publications

Publications (58)
Article
Retinopathy of prematurity (ROP) is a vasoproliferative disease occurring in premature infants that affects the blood vessels of the developing retina. ROP results in the development of vascular shunts, neovascularization, and in its most severe form tractional retinal detachment. The development of retinal vascular shunts and neovascularization in...
Article
Zhang et al¹ present a prospective, case-control study from a single tertiary referral center in China, investigating the association of allergic conjunctivitis (AC) with the health-related quality-of-life (QOL) scores on a questionnaire administered to pediatric patients and their parents. The investigators describe 92 patients with AC and 96 age-...
Article
Objective To evaluate the clinical safety and efficacy of the novel Wright hang-back recession with fibrin glue for the treatment of horizontal strabismus. Study Design Retrospective, case-controlled clinical study comparing surgical outcomes of the Wright hang-back rectus recession with fibrin glue (WHBG) versus standard fixed suture rectus reces...
Article
Mosaic Trisomy 8 is a rare chromosomal abnormality estimated to occur one in 30,000 newborns. The phenotype is highly variable and the severity does not appear to be correlated with the proportion of cells that contain the additional chromosome. Ocular involvement in Trisomy 8 mosaicism has previously been described to include corneal opacities, re...
Article
Objective: Nondepolarizing neuromuscular blocking drugs have been advocated for accurate forced duction testing (FDT) during strabismus surgery. The purpose of this study was to evaluate the literature on use of muscle relaxants (MRs) in strabismus surgery and to evaluate the current practice of pediatric ophthalmologists. Design: Systematic rev...
Article
Full-text available
Purpose: To demonstrate the validity of a new 3D-printed silicone model for practicing strabismus surgery, compared with the rabbit head, in terms of simulator fidelity. Methods: In this multicenter study, a validated questionnaire was developed to assess fidelity of the model and rabbit head. Participants were asked to rate overall globe, conju...
Article
Vitamin D has emerged as a potentially important molecule in ophthalmology. To date, all ophthalmic data pertaining to vitamin D has been restricted primarily to tear and serum analysis in human patients. Considering the isolated nature of the eye, we sought to determine the presence of intraocular vitamin D in ocular disease. Methods: 25-hydroxy...
Article
Objective: Standard rectus muscle recessions require suturing muscle to sclera posterior to the insertion, which is dangerous as the sclera is thin. Extraocular muscle hang-back recession can avoid the posterior scleral needle pass but has been reported to be unstable. The purpose of this study is to assess the use of N-butyl-2-cyanoacrylate to ai...
Book
Completely updated and revised, the fourth edition provides primary care physicians with must-know information on eye examinations, eye disorders, vision screening, strabismus, dyslexia, ocular trauma, genetic syndromes, and all pediatric-specific eye issues likely to be encountered in primary care. https://shop.aap.org/pediatric-ophthalmology-for-...
Article
In Reply Thank you to the authors for their comments. My Invited Commentary¹ was based on the original manuscript submitted by the authors. I was not privy to the final revised and published article² in which the description of the study was modified and elaborated on relative to the original description. Several of the points I had mentioned in my...
Article
We report the case of an 11-year-old girl with a rare finding of silicone oil migration into the periorbital space surrounding an extraocular muscle, discovered during strabismus surgery for a sensory exotropia that had developed after retinal detachment repair by pars plana vitrectomy with intraocular silicone oil. © 2018 American Association for...
Article
Optical coherence tomography (OCT) use in ophthalmology continues to increase as more indications for and developments of OCT imaging are described. Optical coherence tomography provides objective, quantitative data that allow an accurate diagnosis and monitoring of eye disease, reducing the variability inherent in subjective patient evaluations. H...
Article
Birth-associated ocular trauma is common and often minor, including subconjunctival and retinal haemorrhage and eyelid edema. Significant ocular trauma during birth, usually associated with forceps-assisted delivery, is rarer and can include Descemet's membrane rupture, lid lacerations, hyphema, Purtcher retinopathy, facial nerve palsy, corneal ede...
Article
Periorbital infections after strabismus surgery are rare. We describe the first reported case of necrotizing group A streptococcal infection of the conjunctiva and Tenon's capsule complicating uneventful strabismus surgery in a 23-month-old boy, successfully managed with conservative intraoperative debridement and with targeted local and systemic a...
Chapter
Acquired esotropia requires an urgent consult for at least three important reasons:
Chapter
Historically, inferior oblique surgery was considered extremely difficult and was fraught with complications such as fat adherence, ciliary nerve damage with pupillary dilatation, and intraoperative hemorrhage. More recently, however, the management of inferior oblique overaction has improved substantially. The late Dr. Marshall Parks pioneered met...
Chapter
The adjustable suture technique allows for changing the muscle position in the immediate postoperative period, while the patient is awake. Therefore, this technique has the theoretical advantage of allowing fine tuning of ocular alignment. Unfortunately, fine tuning must be done within the first 24–48 h after the procedure, when the muscle function...
Chapter
Prior to strabismus surgery, an important and seemingly obvious question should be asked: “Why are we operating?” Is our treatment goal to establish binocular fusion, eliminate diplopia, expand the field of binocular vision, correct a compensatory head posture, or simply to improve cosmetic appearance? Establishing the goals prior to surgery helps...
Chapter
An intimate knowledge of anatomy, including the extraocular muscles, periocular fascia, and orbit, is necessary to be an accomplished strabismus surgeon. This chapter reviews anatomical relations relevant to strabismus surgery.
Chapter
Torticollis comes from the Latin word torti, meaning twisted, and collis, meaning neck. Simply speaking, we can consider two types of torticollis: musculoskeletal and ocular. Musculoskeletal torticollis is caused by tight neck muscles (usually the sternocleidomastoid) or a skeletal deformity. With musculoskeletal torticollis, the neck will resist p...
Chapter
Minimally invasive strabismus surgery provides a valuable option for our strabismus patients with small deviations, and offers an additional or alternative treatment option to the use of prism glasses. The techniques described below can be performed in the office under topical anesthesia, are less invasive than standard strabismus muscle surgeries,...
Chapter
The clinical features of superior oblique paresis vary widely depending on the type. Common features include an ipsilateral hypertropia that increases on contralateral gaze, and a positive head tilt test with the hypertropia increasing on head tilt to the side of the hypertropia. Congenital superior oblique paresis is commonly associated with ipsil...
Chapter
Vertical transposition of horizontal muscle insertions is an effective means of collapsing an A or V pattern (Fig. 15.1), but only if there is no significant oblique overaction. If oblique overaction is present, appropriate oblique muscle surgery should be performed.
Chapter
For most reoperations, standard recession and resection techniques can be used. The major difference from surgery on a virgin muscle is the need to mobilize the conjunctiva in front of and over the muscle. Reoperation for a lost muscle or for strabismus after retinal detachment surgery, however, tends to be technically more difficult and requires s...
Chapter
The faden operation, also termed posterior fixation suture, is used to weaken the rotational force of a rectus muscle when the eye rotates towards the faden muscle. Faden is the German word for suture, so it is inappropriate to call the procedure “faden suture” (i.e., suture-suture).
Chapter
An esotropia (ET) presenting during the first 6 months of life is termed infantile esotropia. Of the various presentations of infantile esotropia, these are the most common:
Chapter
The superior oblique tendon can be functionally divided into the anterior one third, which is responsible for intorsion, and the posterior two thirds, which is responsible for depression and abduction (Fig. 18.1). Superior oblique tightening procedures are based on this physiologic division and either tighten the whole tendon (i.e., full tendon tuc...
Chapter
The two most useful rectus muscle tightening procedures are the rectus muscle resection and the rectus muscle plication. Rectus muscle tucking has not proven reliable, as it tends to loosen over time. A tuck is a muscle-to-muscle union. Because the muscle fibers are longitudinal and the transverse fibers are weak, the sutures tend to pull out and s...
Chapter
Topical anesthesia strabismus surgery reduces the systemic risk associated with general anesthesia, as well as the postoperative nausea and vomiting. It also eliminates the risk of globe perforation, optic nerve damage, and myotoxicity that is associated with retrobulbar injection. Topical anesthesia can be especially useful in senior citizens who...
Chapter
Transposition surgery is based on changing the location of the muscle insertion so the muscle pulls the eye in a different direction (i.e., changes the vector of forces). Transposition surgeries can be used to treat a rectus muscle paresis, a lost muscle, A and V patterns (Chap. 15), small vertical tropias (Chap. 15), and torsion (Chap. 15). Three...
Chapter
Adequate surgical exposure is the key to any operation. Good exposure starts with proper positioning of the patient. The top of the head should be positioned at the very end of the surgical table, placing the neck in an extended position so the chin is higher than the forehead (Fig. 10.1). Extending the neck lowers the superior orbital rim and eyeb...
Chapter
The pathophysiology is congenital agenesis of the sixth nerve nucleus and innervational misdirection of part of the medial rectus nerve to the lateral rectus muscle. The result is limited abduction and co-contraction of the medial and lateral recti on adduction. The co-contraction causes the globe to retract, producing lid fissure narrowing on addu...
Article
Adenoid cystic carcinoma (ACC) of the lacrimal gland is the most common primary malignant tumor of the lacrimal gland. It typically affects patients in the fifth decade of life and presents with rapid progression of pain, ptosis, motility disturbances, and sensory deficits of less than 1 year's duration. ACC is rare in children. Due to early, aggre...
Article
Full-text available
The growing complexity of medical and surgical care has resulted in increasing subspecialization. To date, data have been lacking regarding the degree to which subspecialization has affected the provision of strabismus surgical services. This gap is important to address given the implications for health care human resources planning and educational...
Chapter
Amblyopia is poor vision caused by abnormal visual stimulation during early visual development. The abnormal visual stimulation disrupts neurodevelopment of visual centers in the brain. Abnormal stimulation can arise from a blurred retinal image, or strabismus with strong fixation preference for one eye and cortical suppression of the nondominant e...
Chapter
Superior oblique tendon weakening procedures are used in the management of various types of strabismus, including superior oblique overaction, inferior oblique palsy, and Brown’s syndrome (see Chap. 7). Most procedures weaken the superior oblique muscle by slackening the tendon. Uncontrolled procedures include tenotomy and tenectomy, in which the t...
Chapter
This chapter gives a detailed description of the rectus muscle recession procedure. Two conjunctival approaches are presented: fornix and limbal.
Chapter
Chronic graft-versus-host disease (cGVHD) is the leading cause of late morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplant (HSCT) [1, 2].Chronic GVHD and its associated complications result in increased resource utilization, poor quality of life parameters, and decreased overall survival in patients. Early d...
Article
To report the use of amniotic membrane transplant in patients with restrictive strabismus. Retrospective, interventional case series. Patients with restrictive strabismus treated with amniotic membrane transplantation. Chart review of 7 consecutive patients (8 eyes) who developed restrictive strabismus after periocular surgery and were treated with...
Article
To determine whether a relationship exists between the timing of feeding before retinopathy of prematurity (ROP) eye examinations and gastric side effects or distress associated with this examination. A prospective, randomized, single-masked study was conducted involving infants in the neonatal intensive care unit who required an ROP eye examinatio...
Article
Case report: Infectious keratitis after laser-assisted in situ keratomileusis (LASIK) is a rare complication that may be challenging to diagnose and treat. We discuss some of the reasons for difficulties diagnosing postoperative atypical or nontuberculous mycobacterial infection and establishing an effective treatment, with reference to reports of...
Article
To evaluate the safety and outcomes of simultaneous bilateral cataract surgery (SBCS). York Finch Eye Associates and Humber River Regional Hospital, Toronto, Ontario, Canada. This retrospective study reviewed the results of 1020 consecutive patients (2040 eyes) who had SBCS by endolenticular phacoemulsification through a clear corneal incision on t...
Article
Full-text available
Iron deficiency and marginal vitamin A (VA) deficiency frequently coexist and affect billions of people, mostly children and women, worldwide. The effects of these micronutrient deficiencies alone and in combination on hematologic, biochemical and molecular indices of iron and VA status were investigated in a 2 x 2 randomized blocked study conducte...
Article
In order to confer water solubility to the benzotetrazepinone ring system, the synthesis of 12 was undertaken. The design and synthesis of 12 were based upon previously established structural requirements for the stability of the 1,2,3,5-tetrazepin-4-one ring system. Tetrazepinone 12 was extremely water soluble and was 10-fold more potent than its...

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