Yi-Fen Cheng

Yi-Fen Cheng
Taipei Veterans General Hospital

PhD

About

152
Publications
12,490
Reads
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1,977
Citations
Additional affiliations
June 2009 - June 2017
Academia Sinica
Position
  • PhD Student
July 2007 - August 2009
Position
  • gastric carcinoma
July 2007 - July 2009
Chang Gung University
Position
  • Master's Student
Education
August 2009
Defense Medical collegue
Field of study

Publications

Publications (152)
Article
Purpose The purpose of this study was to assess the safety and efficacy of drug-eluting embolic (DEE) transarterial chemoembolization for hepatocellular carcinoma (HCC) in patients who are ineligible for curative treatment, using doxorubicin-loaded Tandem (Varian Medical) microspheres. Materials and Methods Between October 2015 and December 2017,...
Article
Full-text available
The original version of this Article contained an error in the affiliation of the second author, Ya-Ting Chang. The correct affiliations for Ya-Ting Chang are Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan and International Graduate Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei 115,...
Chapter
The prevalence of chronic pain increases with age. The pain occurrence in the elderly ranges from 25% to 80% in different countries. Ischemic heart disease is also prevailing in the aged people. Restored blood flow quickly rescues myocardium but also causes ischemia-reperfusion (IR) injury. Brief episodes of ischemia at a distant organ could reduce...
Article
Full-text available
Myocardial infarction is the leading cause of death worldwide. Restoration of blood flow rescues myocardium but also causes ischemia-reperfusion injury. Here, we show that in a mouse model of chronic neuropathic pain, ischemia-reperfusion injury following myocardial infarction is reduced, and this cardioprotection is induced via an anterior nucleus...
Article
Liver regeneration and donor safety in right-lobe (RL) and left-lobe (LL) grafts are essential for donors in living donor liver transplantation (LDLT). Our aim was to compare the liver regeneration rate and postoperative outcome between different donor graft types in LDLT. A total of 95 donors were divided into 2 groups: RL (n = 42) and LL (n = 53...
Article
Liver transplantation for intrahepatic cholangiocarcinoma is notorious for rapid recurrence with poor survival rate postoperatively and has therefore been discontinued in most centers. The purpose of this study is to distinguish hepatocellular carcinoma (HCC) from cholangiocarcinoma in pretransplantation imaging evaluation by dynamic contrast-enhan...
Article
Vascular anatomy is essential in pretransplantation survey. The purpose of this study is to investigate the feasibility and diagnostic performance of inflow sensitive inversion recovery (IFIR) magnetic resonance angiography (MRA) to evaluate the recipient's hepatic vasculature before liver transplantation. Thirty-one pre–liver transplantation pati...
Article
Primary liver malignancy is the leading cause of cancer death worldwide, with hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) representing the majority. Combined HCC-CC, in contrast, accounts for less than 5% of these liver cancers and has not been clearly characterized by imaging, making diagnosis and management difficult. This retrosp...
Article
Optimal hepatic venous tributary flow is correlated with liver function and regeneration. In left-lobe graft living donor liver transplantation, the stump of segment 5 and 8 hepatic veins (S5V and S8V) are ligated without performing hepatic tributary reconstruction. The aim of this article was to evaluate the different dominate hepatic vein pattern...
Article
Portal vein (PV) stenosis is not uncommon in post-transplantation pediatric living-donor liver transplant (PLDLT) recipients. The purpose of this study was to identify specific ultrasound criteria that may be used to detect PV stenosis in PLDLT with left-liver grafts. From January 2010 to October 2014, 87 pediatric recipients underwent PLDLT with...
Article
The majority of hepatocellular carcinoma (HCC) patients is diagnosed in late stages and therefore becomes ineligible for potentially curative treatment such as resection or liver transplantation. Transarterial chemoembolization (TACE) with drug-eluting beads (DC beads, Biocompatibles, Farnham, United Kingdom) has been proven with less side effects...
Article
Portal vein (PV) steno-occlusive disease is a known vascular complication after liver transplantation. The use of portal venous stenting (PVS) is encouraging because it provides longer vessel patency. The purpose of this study is to assess the therapeutic usefulness of self-expandable PVS in pediatric living donor liver transplantation (LDLT) recip...
Article
Spontaneous intracranial hypotension (SIH) is characterized by orthostatic headache. Typical abnormal magnetic resonance imaging (MRI) findings have been considered to be the sine qua non of SIH, but a sizeable minority of patients has normal results using conventional MRI. The purpose of this study was to evaluate the difference in cerebrospinal f...
Article
Adipose-derived mesenchymal stem cells (ASCs) have been considered to be attractive and readily available adult mesenchymal stem cells (MSCs) and are becoming increasingly popular for use in regenerating cell therapy. However, recent evidence attributed a fibrotic potential to MSCs which differentiated into myofibroblasts with highly increased α-sm...
Article
Objective Due to the shortage of cadaver liver grafts in Asia, more than 90% of biliary atresia (BA) patients require living donor liver transplantation (LDLT), but the factors that influence liver graft regeneration in pediatric patients are still unclear. The aim of this study was to evaluate the potential predisposing factors that encourage live...
Article
Background The recipient's hepatic vascular anatomy is essential in living-donor liver transplantation (LDLT). Magnetic resonance angiographic inflow-sensitive inversion recovery (IFIR-MRA) is a new noncontrast technology for vascular evaluation, particularly for those patients with renal function impairment. The purpose of this study was to improv...
Article
Objective This study aimed to determine whether coronary vein size can serve as a predictor of hemodynamic instability during inferior vena cava clamping in living-donor liver transplantations. Methods Fifty-two patients' hemodynamic data before and after clamping were retrospectively analyzed and compared with the use of linear regression and rep...
Article
Objective The relationship between portal pressure and small-for-size syndrome (SFSS) is unsettled. The purpose of this study was to evaluate the role of portal pressure in predicting SFSS. Methods Thirty-four patients with end-stage liver disease who received adult-to-adult living-donor liver transplantation (ALDLT) were included. Recipients were...
Article
The acoustic radiation force impulse elastography (ARFI) is a new technology of elastography integrated into B-mode ultrasonography. It has been a reliable method to evaluate liver fibrosis of chronic liver disease in recent years, but less applied in the posttransplantation liver. The aim of the study was to evaluate liver fibrosis by the ARFI wit...
Article
Full-text available
Background: Early pulmonary edema is common after orthotopic liver transplantation. Associated pathogenic mechanisms might involve increased activity of cardiac-inhibitory systems due to increased vasodilator production, mainly nitric oxide (NO). NO is primarily responsible for flow-mediated vasodilatation (FMD). We investigated the incidence of pu...
Article
Full-text available
Background: Early pulmonary edema is common after orthotopic liver transplantation. Associated pathogenic mechanisms might involve increased activity of cardiac-inhibitory systems due to increased vasodilator production, mainly nitric oxide (NO). NO is primarily responsible for flow-mediated vasodilatation (FMD). We investigated the incidence of p...
Article
This is a retrospective study. The purpose of this study was to assess the diagnostic accuracy and utility of posttransplant magnetic resonance cholangiography (MRC) in detecting biliary complications and planning the treatment. From July 2006 to April 2010, 51 (19%) of these 268 adult living-donor liver transplantation (LDLT) recipients were refer...
Article
Hepatocellular carcinoma (HCC) is the second leading cause of cancer related death in Taiwan. However, HCC recurrence after living donor liver transplantation (LDLT) is an undesirable outcome, and the treatment is controversial due to different recurrent patterns. The aim of this study is to evaluate the efficacy of transarterial embolization (TAE)...
Article
Gastric cancer is the sixth leading cause of cancer-related death in Taiwan, and the identification of related factors is essential to increase patient survival. ADP-ribosylation factor 1 (ARF1) was initially identified using 2-D electrophoresis combined with MALDI-time-of-flight mass spectrometry. ADP-ribosylation factor 1 belongs to the Ras super...
Article
Recent proteomic approach allows us to target on specific molecules underlying the common mechanism between experimental and clinical liver allograft tolerance. Especially, new insight has been gained from our studies since we found that post-transplant autoimmune responses with high titer of anti-nuclear antibodies against histone H1 and high mobi...
Article
To evaluate the postoperative portal vein stenosis (PVS) and the diagnostic efficiency of Doppler ultrasound (DUS) in adult living donor liver transplantation (ALDLT). From January 2007 to December 2008, 103 ALDLTs were performed and postoperatively followed by routine DUS. The morphologic narrowing at the anastomotic site (AS) of the PVS was analy...
Article
Placenta previa accreta, the combination of placenta previa and placenta acrreta, can cause life-threatening massive post-partum hemorrhage (PPH) and may require emergent hysterectomy. Intraoperative transcatheter arterial embolization (TAE) performed after fetal delivery and before placenta expulsion can significantly reduce blood loss and preserv...
Article
Our aim is to review the imaging findings of glycogen storage disease (GSD), both pre and post liver transplantation. From March 1996-October 2006, 13 living donor liver transplantation and one split liver transplantation for GSD were performed. The transplant records were reviewed. There were 9 female and 5 male patients. All were non-responsive t...
Article
The purpose of this study was to assess factors influencing the end-tidal concentrations of isoflurane within a bispectral index (BIS) range of 45–55 among healthy live liver donors (n = 11), chronic hepatitis B patients undergoing hepatectomy hepatocellular carcinoma (n = 10), and end-stage liver disease patients undergoing liver transplantation (...
Article
We sought to compare the effects of operation room temperature (ORT) at typical ambient environment (19-21 degrees C) and ORT at 24 degrees C on the core temperature of patients undergoing living donor hepatectomy. Sixty-two patients undergoing living donor hepatectomy were divided into 2 groups. In group I (n = 31), surgery was performed at typica...
Article
Indoleamine 2,3-dioxygenase (IDO), which catalyzes the breakdown of tryptophan into kyneurenine, has immunologic significance for the induction of maternal tolerance and liver allograft tolerance by inhibiting T-cell activation. In the present study, we compared survival of syngeneic or allogeneic hepatocytes in livers with or without hepatectomy....
Article
We have demonstrated previously that liver allograft tolerance is associated with the immunosuppressive activity of anti-histone H1 autoreactive antibodies induced in the serum of liver transplantation. Furthermore, we and others have shown that nuclear proteins such as histone H1 and high mobility group box 1 play an important role in maturation o...
Article
Background: Bony deformity and muscular malfunction around the shoulder induced by deltoid contracture may influence rotator cuff function and lead to subsequent tearing. The purpose of this study was to investigate the imaging and clinical factors related to rotator cuff tear in patients with deltoid contracture. Methods: We retrospectively review...
Article
Background/Aims: To determine the biochemical data that reliably predict allograft injury from acute rejection (AR) in patients with living related liver transplantation (LRLT), liver function test and histopathological characteristics of AR were compared and analyzed retrospectively. Methodology: From Aug. 1994 to Nov. 2000, 101 cases received ort...
Article
Splenic salvage after trauma has been attempted to avoid lifelong risk for increased susceptibility to infection after splenectomy. Splenic artery embolization (SAE) for patients with blunt splenic injury has been applied in the protocols of splenic salvage. The purpose of this study was to evaluate the efficacy of emergent splenic artery embolizat...
Article
To evaluate the effectiveness and safety of transcatheter uterine artery embolization (UAE) using lipiodol-gelfoam cube mixture for the treatment of symptomatic uterine leiomyomas. Fifty women with symptomatic uterine leiomyomas underwent transcatheter bilateral UAE using lipiodol and gelfoam cubes. Ultrasonography was used to assess the size of ut...
Article
Background: Adenoid cystic carcinoma of the breast is an uncommon histologic form of breast cancer, comprising in most series less than 1% of all mammary cancers. Due to the rarity, little information about its presentation on image studies has been noted in the literature. Here we report two additional cases with emphasis on the intriguing image p...
Article
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Article
Objective: To investigate and quantify clinical outcomes and spectral Doppler analyses of uterine arteries in patients with myoma undergoing uterine artery embolization (UAE) with gelatin sponge particles and lipiodol. Design: Prospective observational study. Setting: Tertiary medical center. Patient(s): Forty premenopausal women with symptomatic m...
Article
To present the neglected radiographic signs of renal squamous cell carcinoma (RSCC). Twenty-eight cases of RSCC were retrospectively reviewed. Two radiographic signs were elaborated as follows: separating nephroliths sign was defined as change of distance or orientation between two or more renal stones on comparison of two sequential radiographs, w...
Article
The fifth edition of the American Joint Committee on Cancer (AJCC) staging manual defines new rules for staging nasopharyngeal carcinoma. The authors tested the value of this new system by applying these rules retrospectively to their previously treated patients and comparing the results with those obtained using the fourth edition of the AJCC stag...
Article
Full-text available
The effect of fatty liver on graft survival, especially with reference to macrovesicular and microvesicular steatosis, is still uncertain. This preliminarily study was designed to create a noninvasive method for the quantification of the hepatic fat content in vivo and to establish provisional criteria for the assessment of fatty donor livers befor...
Article
To determine the wrist angle that produces the least compression to the median nerve and to evaluate the usefulness of sonography in determining the optimal position. Seventeen wrists of 17 healthy volunteers received dynamic, high-frequency (8 MHz), high-resolution sonography with the wrist splinted at various positions: 15 degrees of flexion, neu...
Article
Biliary tract reconstruction has long been considered the Achilles' heel of liver transplantation as biliary complications can increase morbidity and mortality especially in partial liver graft transplantation. Thirty-four living related liver transplants were performed at Chang Gung Memorial Hospital in Kaohsiung for 33 children and 1 adolescent d...
Article
Hepatic venous reconstruction is critical in living donor liver transplantation because outflow obstruction may lead to graft dysfunction or loss. We describe our experience and analyze outcomes with a technique of creating a single outflow tract using venoplasties of the graft and recipient hepatic veins. A retrospective study was done on 38 conse...
Article
We investigated whether transtracheal insufflation of oxygen with different insufflation flow rates protects against aspiration of gastric contents during cardiopulmonary resuscitation (CPR). Its ventilation and oxygenation effects were also evaluated. Cardiac arrest was induced in anesthetized and paralyzed 18 mongrel dogs. Chest compression using...
Article
Meckel's diverticulum is the most common anomaly of the gastrointestinal tract and usually produces no symptoms, although the classic symptom is painless rectal bleeding in a child. Because most symptomatic diverticula in children contain ectopic gastric tissue, radionuclide imaging using a technetium 99m pertechnetate scan is considered to be the...