Yenny Angela

Yenny Angela
Hannover Medical School | MHH · Trauma Department

About

15
Publications
798
Reads
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8
Citations
Citations since 2017
14 Research Items
8 Citations
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201720182019202020212022202301234567
201720182019202020212022202301234567
201720182019202020212022202301234567

Publications

Publications (15)
Article
Full-text available
For patients with advanced basal cell carcinoma (aBCC) first-line treatment with hedgehog inhibitors (HHIs) and second-line treatment with PD1 inhibitors (PD1i) is available, offering combination and sequencing options. Here, we focus on the efficacy and safety of HHI reinduction after PD1i failure. Retrospective data analysis was performed with 12...
Article
The medical treatment options of advanced cutaneous and mucosal melanoma markedly improved during the last 10 years. This improvement is due to checkpoint-inhibitors targeting PD‑1 and CTLA‑4 as well as tyrosine kinase inhibitors targeting BRAF and MEK. Current studies investigate new checkpoints such as LAG‑3 as well as combinations and sequences...
Article
Syphilis, caused by the bacteria Treponema pallidum subspecies pallidum, is an infectious disease transmitted through direct, most frequently sexual, contact with infected mucosal lesions. In the last two decades the numbers of cases reported to the Robert Koch Institute (RKI) increased from around 2000 cases in 2000 to 7889 cases in 20191. Syphili...
Article
Objectives Immune checkpoint inhibitor therapy has revolutionized the management of multiple cancers with previously poor prognosis. Despite its efficacy the therapy is associated with a wide spectrum of immune‐related adverse events including neurological deficits ranging from peripheral neuropathy, myopathy, and myasthenic syndromes, to encephalo...
Article
Langerhans cell histiocytosis (LCH) depicts a rare disease belonging to the group of histiocytoses. The disease is based on a clonal expansion of myeloid precursors. Frequently, gain‐of‐function mutation in the MAPK signaling pathway can be detected.1,2 In 2016, Emile et al. proposed a revised classification of histiocytoses and neoplasms of the ma...
Article
The literature reveals evidence for a gender specific outcome after major trauma and hemorrhage. Increased levels of male sex hormones such as testosterone and even more dihydrotestosterone (DHT) mediate negative effects on the posttraumatic immune response. Pretreatment with finasteride several days before trauma hemorrhage (TH) led to improved ou...

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