Yazan Ranneh

Yazan Ranneh
University College Cork | UCC · School of Nutritional Sciences

BSc, MSc, PhD in Nutrition

About

29
Publications
26,014
Reads
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646
Citations
Citations since 2017
17 Research Items
569 Citations
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
Introduction
Yazan Ranneh currently does research in Nutrition and Dietetics and, Nutritional Biochemistry.
Additional affiliations
January 2020 - present
Universiti Tun Hussein Onn Malaysia
Position
  • PostDoc Position
September 2012 - present
Universiti Putra Malaysia
Position
  • Research Assistant
Education
September 2015 - November 2018
Universiti Putra Malaysia
Field of study
  • Clinical Nutrition
January 2015 - May 2015
Shaw academy
Field of study
  • Nutrition
September 2011 - April 2014
Universiti Putra Malaysia
Field of study
  • Nutritional Sciences

Publications

Publications (29)
Article
Full-text available
Sweet potato peel (SPP), which consist of various natural bioactive compounds, could play an important role in ameliorating chronic diseases such as cancer, cardiovascular diseases, and other degenerative diseases and yet remained underutilized. The current study investigated the effect of orange or purple SPP powder at different level of substitut...
Article
Objective: To determine the lead bioactive compound in kernel extract of Mangifera pajang and its anti-cancer activity against human breast cancer cell lines with positive estrogen receptor (MCF-7). Methods: The methanolic extract of dried powder kernel of Mangifera pajang was exposed to column chromatography for isolation. The structural elucidati...
Article
Full-text available
Aging is a naturally biological process with adverse effects. The continuous accumulation of reactive oxygen species (ROS) trigger cellular and tissue damage by activating several aging enzymes. The antioxidant properties of traditional medicinal plants used by Jakun aborigine's community are a promising approach to alleviate aging process and prev...
Article
Full-text available
Inflammation is the main key role in developing chronic diseases including cancer, cardiovascular diseases, diabetes, arthritis, and neurodegenerative diseases which possess a huge challenge for treatment. With massively compelling evidence of the role played by nutritional modulation in preventing inflammation-related diseases, there is a growing...
Article
Full-text available
Breast cancer is among the most commonly diagnosed cancer and the leading cause of cancer-related death among women globally. Malaysia is a country that is rich in medicinal plant species. Hence, this research aims to explore the secondary metabolites, antioxidant, and antiproliferative activities of Dioscorea bulbifera leaf collected from Endau Ro...
Article
Background: Systemic acute inflammation is the hallmark of sepsis and associated with multiple organ dysfunction. Objective: This study investigated the potential of stingless bee honey (SBH) to suppress lipopolysaccharide (LPS)-induced systemic acute inflammation in rats and to reveal the probable mechanism of action. Methods: Rats received 4...
Article
Full-text available
Background: The X-chromosome has been suggested to play a role in prostate cancer (PrCa) since epidemiological studies have provided evidence for an X-linked mode of inheritance for PrCa based on the higher relative risk among men who report an affected brother(s) as compared to those reporting an affected father. The aim of this study was to exam...
Article
Full-text available
Prostate cancer (PCa) is a challenging polygenic disease because the genes that cause PCa remain largely elusive and are affected by several causal factors. Consequently, research continuously strives to identify a genetic marker which could be used as an indicator to predict the most vulnerable (i.e., predisposed) segments of the population to the...
Article
Full-text available
The aim of the present mini-review was to report a toxic effect of dimethyl sulfoxide (DMSO) that has indicated to change the histology of the liver and kidney of rats. DMSO is a powerful co-solvent and often is used in early metabolic studies when compounds are poorly characterized and difficult to become soluble in water. To become soluble, they...
Article
Full-text available
Chronic subclinical systemic inflammation has a key role in stimulating several chronic conditions associated with cardiovascular diseases, cancer, rheumatoid arthritis, diabetes, and neurodegenerative diseases. Hence, developing in vivo models of chronic subclinical systemic inflammation are essential to the study of the pathophysiology and to mea...
Article
Full-text available
Background Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, arthritis, type 2 diabetes, and cardiovascular and neurodegenerative diseases. This study examined the protective effect of stingle...
Article
Cereal derived arabinoxylans (AXs) are non-starch polysaccharides that have immunomodulatory activities. These activities are thought to be related to the low molecular weight fractions of AXs. Wheat and wheat by-products are rich in AXs, however, the water extractable fraction of AXs in wheat products is low. Water extraction of AXs can be improve...
Article
Arabinoxylans (AXs) are major dietary fibre in cereals. Recently, AXs have attracted a great deal of attention because of their biological activities. These activities have been suggested to be related to the content of low molecular weight (Mw) AXs, in particular those with Mw below 32 kDa. Rice bran is a rich source of AXs. However, water extract...
Article
Purpose - The purpose of this review is to discuss recent research on arabinoxylans from rice bran and wheat by-products and their immunomodulatory potential. Also, a potential receptor for arabinoxylans is proposed in relation to arabinoxylan structure. Design/methodology/approach - This review summarises recent publications on arabinoxylans from...
Article
Humans are exposed to harmful pathogens and a wide range of noxious substances every day. The immune system reacts to, and destroys, these pathogens and harmful substances. The immune system is composed of innate and adaptive immunity, which liaise to protect the host and maintain health. Foods, especially cereals, have been reported to modulate th...
Article
This study aims to examine and compare the phenolic profile and antioxidant properties of two kinds of honey: Stingless bee honey (Kelulut honey) and Tualang honeys. Using liquid chromatography mass spectrometry, a total of eighteen phenolic acids and flavonoids have been identified in Kelulut honey samples. The phenolic content and total antioxida...
Article
Full-text available
The inflammation process in the human body plays a central role in the pathogenesis of many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a decisive role in human body, particularly in physiological and pathological process. The chronic inflammation state could generate several types of diseases such as cancer, athe...
Article
Full-text available
Cocoa is a rich source of polyphenols that has been traditionally used as the treatment of several types of inflammation related disease. The response to inflammation comprises the consecutive release of mediators and the enlistment of circulating leukocytes, such as macrophages. Currently, Cocoa-derived polyphenolics have shown anti-inflammatory e...
Article
Full-text available
The roles of Omega-3 FAs are inflammation antagonists, while Omega-6 FAs are precursors for inflammation. The plant form of Omega-3 FAs is the short-chain α-linolenic acid, and the marine forms are the long-chain fatty acids: docosahexaenoic acid and eicosapentaenoic acid. Omega-3 FAs have unlimited usages, and they are considered as omnipotent sin...
Conference Paper
Full-text available
Cocoa was applied for therapeutic purposes to cure several disorders such as fever, indigestion, angina, heart, liver and lung diseases (Keen, 2001; Seligson et al., 1994). Polyphenols that widely founded in plants food are the primer antioxdative part of cocoa branching to various subclasses compounds such as flavanols and procyanidins. Reported i...
Article
Full-text available
The existence of reactive oxygen species among cells at high ratio is associated with different types of disorders. A link between exogenous antioxidant supplementation and reducing oxidative stress remains unclear. Since a grave concern has been raised regarding synthetic antioxidant usage, justifying an alternative treatment is required. Cocoa, a...
Article
Full-text available
Almost all countries are facing obesity endemic, although great variation exists between and within countries. Sedentary lifestyle and high fat (high caloric) diet have increased globally as a result of industrial, urban and mechanic changes of developing countries. Improved economic status promotes the obesity and metabolic syndrome in all age gro...
Article
Full-text available
Colon cancer is considered one of the primary causes of death-related cancer in Western universe. Although it is recommended in most of advanced cases of this disease, cytotoxic chemotherapeutic agents are relatively become ineffectual. Increasing the dietary intake of fruits and vegetables in order to reduce this disease is thought to be a viable...
Article
Full-text available
A decrease in the lineage commitment of multipotent Mesenchymal stem cells (MSC) to the bone forming osteoblast lineage and an increase in the commitment to the fat forming adipocyte lineage is more common in bone marrow of elderly persons. A link between methylation status and MSC differentiation remains unclear. Therefore, we hypothesize that hyp...
Article
Full-text available
Osteoporosis is associated with a decrease in the commitment of Mesenchymal stem cells (MSC) to the bone forming osteoblast lineage and an increase in the commitment to the fat forming adipocyte lineage in bone marrow of elderly persons. A link between methylation pathway and MSC differentiation remains unclear. Therefore, we hypothesize that al...
Article
Full-text available
The antioxidant components of cocoa powder, which is rich in polyphenols, were isolated using column chromatography and high performance liquid chromatography. Polyphenolic compounds were then characterized by high-performance liquid chromatography/Ultraviolet and electronspray ionization—tandem mass spectrometry (HPLC-UV-/ESI-MS-MS). As a result,...
Article
Full-text available
Colon cancer is considered one of the primary causes of death-related cancer in Western universe. Although it is recommended in most of advanced cases of this disease, cytotoxic chemotherapeutic agents are relatively become ineffectual. Increasing the dietary intake of fruits and vegetables in order to reduce this disease is thought to be a viable...
Article
Full-text available
Background: Angiopoietin-like protein 4 (Angptl4) is a new circulating protein of the Angiopoietin-like family, predominantly expressed in adipose tissue and liver. A link between Angptl4 and the levels of free fatty acids in human blood plasma remains unclear. Therefore, we hypothesized that any alteration in the concentration of plasma Angptl4 ma...

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Projects

Projects (3)
Project
My goal is to prove that dietary fibres are more than just prebiotics to gut microbiota. DF can be re-modulated to penetrate the lumen of the gut.
Archived project
The aim of this project is to compare the nutritional content, phenolic profile, antioxidant and anti-inflammatory between stingless bee honey and Tualang honey.