
Yavuz AyarBursa City Hospital · Nephrology and Internal Medicine
Yavuz Ayar
MD. Assoc Prof
About
144
Publications
24,584
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518
Citations
Introduction
Additional affiliations
August 2018 - present
Bursa State Hospital, Bursa, Turkey
Position
- Medical Doctor
August 2016 - August 2018
Sırnak State Hospital, Sırnak, Turkey
Position
- Medical Doctor
April 2013 - April 2016
Publications
Publications (144)
Background
We evaluated the efficacy of different immunosuppressive regimens in patients with primary membranous nephropathy in a large national cohort.
Methods
In this registry study, 558 patients from 47 centers who were treated with at least one immunosuppressive agent and had adequate follow-up data were included. Primary outcome was defined a...
Each year, millions face natural disasters, encountering mass fatalities and severe medical issues such as crush injuries and crush syndrome. Crush syndrome, marked by acute kidney injury (AKI) and hyperkalemia, correlates with mortality. This study focuses on presenting epidemiological data on kidney disease resulting from the February 6, 2023 ear...
Objective:The increase in the need for organs and decrease in the cadaver pool have led to a tendency towards organ transplantation from marginal donors. In our study, patients who underwent transplantation based on the standard and expanded donor criteria were compared in terms of factors affecting graft survival.
Methods:Data of patients who unde...
Introduction
Peritoneal dialysis (PD) remains understudied in disaster nephrology. This retrospective multicenter study explores the experiences of PD survivors following the February 6, 2023, Kahramanmaraş Earthquake.
Methods
Adult PD patients from 11 affected cities were analyzed to assess challenges faced during and postearthquake, alongside cl...
IgG4‐related disease is an inflammatory, multisystemic disease that affects the immune system. The disease progresses to fibrosis due to inflammation. Retroperitoneal fibrosis is a serious complication. Pancreas, biliary tract, glands, thyroid, lymph nodes, etc. may be involved. Prognosis is usually subacute, and seen in middle age and advanced men...
Introduction
We aimed to evaluate the relationship between the hand fine motor skills of peritoneal dialysis (PD) practitioners and PD‐related peritonitis.
Methods
This multicenter prospective observational study was conducted with 120 incident PD patients. Patients were divided into two groups who had PD‐related peritonitis within the first year...
Background
We aimed to determine the risk factors that may be associated with colistin-induced acute kidney injury (AKI) to promote the safer use of colistin in the treatment of nosocomial infections caused by multidrug-resistant Gram-negative bacteria in intensive care units.
Materials and methods
This retrospective observational study was conduc...
Background and Aims
In resistant infections and septic patients, the choice of colistin in the selection of antibiotic therapy is important in the treatment response. Kidney damage is common after antibiotic use. In our study, we evaluated the clinical and laboratory data of the patients who developed nephrotoxicity after the use of colistin, follo...
Background and Aims
We aimed to investigate the characteristics and survival data of biopsy-proven primary focal segmental glomerulosclerosis (FSGS) in adult patients across Turkey.
Method
Patients with primary FSGS were included by retrospectively scanning the database of the Turkish Society of Nephrology Glomerular Diseases Study Group (TSN-GOLD...
Aim
In resistant infections and septic patients, the choice of colistin in the selection of antibiotic therapy is important in the treatment response. Kidney damage is common after antibiotic use. In our study, we evaluated the clinical and laboratory data of the patients who developed nephrotoxicity after the use of colistin, followed in the inten...
Objectives: Renal artery stenosis (RAS) is among the most common causes of secondary hypertension. Prevalence of RAS are seen in end-stage renal disease (ESRD) patients with hypertension between 1-10%. In our study, we evaluated the data of patients with RAS who were followed up with medical treatment and stenting. Methods: In our study, patients w...
Background
This study was designed to investigate the effect of calcineurin inhibitors (CNIs), cyclosporine (CsA), and tacrolimus (Tac) on anthropometrics in kidney transplant recipients.
Methods
111 of 128 adult kidney transplant recipients who received post-transplant CNIs were included in this retrospective study. Anthropometrics were recorded...
Introduction:
There are not enough data on the post-CO-VID-19 period for peritoneal dialysis (PD) patients affected from COVID-19. We aimed to compare the clinical and laboratory data of PD patients after COVID-19 with a control PD group.
Methods:
This study, supported by the Turkish Society of Nephrology, is a national, multicenter retrospectiv...
Background
The histopathological classification of ANCA-GN divides patients into four groups based on signs of glomerular injury. However, this classification did not consider age-related glomerulosclerosis. In this study, we aimed to compare the prediction of renal survival between Berden's ANCA-GN histopathological classification and ANCA-GN hist...
Background:
We aimed to study the characteristics of peritoneal dialysis (PD) patients with Coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.
Methods:
In this multicenter national study, we included PD patients with confirmed COVID-19...
Purpose
Coronavirus disease 2019 (COVID-19) has a higher mortality in the presence of chronic kidney disease (CKD). However, there has not been much research in the literature concerning the outcomes of CKD patients in the post-COVID-19 period. We aimed to investigate the outcomes of CKD patients not receiving renal replacement therapy.
Methods
In...
BACKGROUND AND AIMS
There is not enough data on the post-COVID-19 (coronavirus disease 2019) period for peritoneal dialysis (PD) patients affected from COVID-19. We aimed to compare the clinical and laboratory data retrospectively obtained in the follow-up of PD patients after COVID-19 with a control PD group.
METHOD
This study, supported by the T...
BACKGROUND AND AIMS
Coronavirus disease 2019 (COVID-19), which started in China in December 2019 and spread all over the world, is more progressive in patients who are elderly and with chronic diseases. Especially, kidney involvement affects the survival of patients. In this study, we analysed COVID-19 patients who developed acute kidney injury tre...
BACKGROUND AND AIMS
Haemodialysis (HD) patients are at increased risk for adverse short-term consequences of COVID-19. In this study, we investigated the characteristics of chronic HD patients in the post-COVID-19 period and compared them with the control group.
METHOD
We conducted a national multicentre observational study involving adult chronic...
BACKGROUND AND AIMS
Although existing data suggest an increased mortality rate, data about the course of coronavirus disease 2019 (COVID-19) in peritoneal dialysis (PD) patients, its short- and long-term effects on the patient and technique survival are limited. Moreover, specific factors associated with increased risk of death have not been clearl...
Background
Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.
Methods
We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A...
Objective: Coronavirus disease 2019 (Covid 19) started in China in December 2019 and spread all over the world, is more progressive in patients who are elderly and with chronic diseases. Especially kidney involvement affects the survival of patients. In this study, we analyzed Covid 19 patients who developed acute kidney injury treated in our unit,...
Objectives: There is limited data about coronavirus disease-19 (COVID-19) characteristics and results in peritoneal dialysis (PD) patients. This study aimed to investigate the characteristics and outcomes among PD patients and compare them with matched hemodialysis (HD) patients and a control group without kidney disease. Methods: We included 18 PD...
IgG4 related disease is an immune-mediated chronic inflammatory disease. It is a multisystemic disease that can lead to retroperitoneal fibrosis with involvement of the pancreas, glands, thyroid, lymph nodes, etc. and characterized histopathologically by lymphoplasmocytic cell infiltration. We evaluated a patient diagnosed with IGG4 related disease...
Objective: Coronavirus disease 2019 (Covid 19) started in China in December 2019 and spread all over the world, is more progressive in patients who are elderly and with chronic diseases. Especially kidney involvement affects the survival of patients. In this study, we analyzed Covid 19 patients who developed acute kidney injury treated in our unit,...
Background:
Coronavirus disease 2019 (COVID-19) is a disease that affects many organs, especially the lung, and may lead to multiorgan failure. Studies describing neurological dysfunctions involving the central and peripheral nervous systems have emerged. In our study, we aimed to evaluate the neurological signs and symptoms in hospitalized patien...
Background
Acute kidney injury (AKI) is common in coronavirus disease-2019 (COVID-19) and the severity of AKI is linked to adverse outcomes. In this study, we investigated the factors associated with in-hospital outcomes among hospitalized patients with COVID-19 and AKI.
Methods
In this multicenter retrospective observational study, we evaluated t...
Background
The histopathological classification of ANCA-GN divides patients into four groups based on signs of glomerular injury. However, this classification did not consider age-related glomerulosclerosis. In this study, we aimed to compare the prediction of renal survival between Berden's ANCA-GN histopathological classification and ANCA-GN hist...
Background and Aims
Acute kidney injury (AKI) is common in coronavirus disease-2019 (COVID-19) and the severity of AKI is linked to adverse outcomes. In this study, we investigated the factors associated with in-hospital outcomes among hospitalized patients with COVID-19 and AKI.
Method
In this multicenter retrospective observational study, we eva...
Background and Aims
The aim of this study was to evaluate the short-term effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease.
Method
Twenty-five diabetic patients received medication containing 2 g/day n-3 PUFA orally in addition to...
Background and Aims
Skin test anergy is common in patients with uremia and during maintenance hemodialysis treatment. However, up to date only one study concerning skin test in peritoneal dialysis patients has focused on the issue. Our cross-sectional controlled study was conducted to analyze the correlation of purifed protein derivative (PPD) test...
Background
We aimed to present the demographic characteristics, clinical presentation, and outcomes of our multicenter cohort of adult KTx recipients with COVID-19.
Methods
We conducted a multicenter, retrospective study using data of patients hospitalized for COVID-19 collected from 34 centers in Turkey. Demographic characteristics, clinical find...
AAbstract Background/aim: Hospital-acquired acute kidney injury (HA-AKI) may commonly develop in Covid-19 patients and is expected to have higher mortality. There is little comparative data looking for the effect of HA-AKI on mortality of chronic kidney disease (CKD) patients and a control group of general population suffering from Covid-19.
Mater...
Abstract Background Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics and determinants of mortality in a large group of MHD patients hospitalized for COVID-19. Methods This multicenter, retrospective, obser...
Objectives: Malnutrition is a common problem in chronic renal disease patients during pre-dialysis and dialysis, leading to increased cardiovascular diseases and mortality. This study aimed to evaluate the efficacy of supplemental protein supplementation on malnutrition in peritoneal dialysis patients. Methods: Eighty-four stable adult peritoneal d...
Background. Chronic kidney disease (CKD) and immunosuppression,
such as in renal transplantation (RT), stand as one of
the established potential risk factors for severe coronavirus disease
2019 (COVID-19). Case morbidity and mortality rates for
any type of infection have always been much higher in CKD,
haemodialysis (HD) and RT patients than in the...
Spondin 2 (SPON2) plays an important role in multiple processes and is a member of the Spondin 2/F-spondin family of extracellular matrix proteins. We investigated serum SPON2 levels and its correlation with renal functions and urine protein excretion in different glomerular diseases. The cohort included 97 consecutive adults with persistant protei...
Background
Dyspepsia is a common disorder in kidney transplant recipients, and the risk of post-transplant complications is increased in candidates with upper gastrointestinal disease. We evaluated gastrointestinal lesions of kidney transplant candidates on dialysis.
Methods
In this study, endoscopic and pathological findings in hemodialysis (HD)...
Introduction: The aim of this study was to evaluate the short-term effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease. Materials and methods: Twenty-five diabetic patients received medication containing 2 g/day n-3 PUFA orally in ad...
Aim:Acute kidney injury (AKI) is still an important cause of morbidity and mortality. Several factors are effective in its frequency, etiology, prognosis and mortality. In our study, we aimed to demonstrate the etiology and prognostic factors of AKI.Methods:A total of 272 patients diagnosed with AKI, who were hospitalized in the nephrology departme...
AimSkin test anergy is common in patients with uremia and during maintenance hemodialysis treatment. However, up to date only one study concerning skin test in peritoneal dialysis patients has focused on the issue. Our cross-sectional controlled study was conducted to analyze the correlation of purified protein derivative (PPD) test response with d...
Introduction. Non-peptide vasopressin receptor antagonists (vaptans) are effective at increasing sodium in euvolemic and hypervolemic states and appear safe. We aimed to evaluate the efficacy of tolvaptan in euvolemic or hypervolemic hyponatremic patients.
Methods. The study included 9 hyponatremic (serum sodium level <125 mmol/L) patients. Serum p...
Introduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia. However, rapid and high increases in neutrophil counts of some patients may occur during treatment. This retrospective study aimed to determine the efficacy and safety of G-CSF treatment in neutrope...
Aim: Uric acid levels increase in chronic renal failure especially due to protein metabolism. In this study, we aimed to compare uric acid clearance who are also nephrotoxic in patients with end-stage renal disease.
Methods: Sixty-one chronic peritoneal dialysis (PD) patients and fifty-one chronic hemodialysis (HD) patients included in the study. D...
Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation. Methods: Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal...
Objectives:
Lymphocele is a well-known postoperative surgical complication after kidney transplant. In this study, our aim was to analyze incidence, risk factors, and outcomes of posttransplant lymphocele in a large cohort.
Materials and methods:
This observational study included 395 consecutive patients (219 males and 176 females) who underwent...
V itamin D is absorbed into the body through exposure to sunlight, a diet of vitamin-fortified foods, and dietary supplements. The major source of vitamin D absorption is through skin synthesis. Vitamin D receptors have been found in various tissues, including the brain, prostate, breast, colon, pancreas, and immune cells. [1] The estimated worldwi...
Objective:
Encapsulating peritoneal sclerosis (EPS) is a serious complication for patients with chronic kidney disease (CKD) who were treated with long-term peritoneal dialysis (PD). The risk of EPS was increased after kidney transplantation. In our study we evaluated risk factors for EPS patients after kidney transplantation who were treated befo...
OBJECTIVE: Early arterial stiffness has been shown in autosomal dominant polycystic kidney disease (ADPKD) patients with preserved renal function. However, to our knowledge, no prospective study evaluated changes in arterial functions in patients with ADPKD. The study aimed to monitor the changes in renal and arterial functions in patients with ADP...
Giriş: ANCA ilişkili vaskülitlerde histopatolojik sınıflama 2010 yılında
tanımlanmıştır. Bu sınıflamada renal biyopsi glomerüler bulguları (normal,
sklerotik ve kresentik) ve yüzdeler değerlendirilmiştir. Bu sınıflamada fokal,
kresentik, sklerotik ve mikst olmak üzere dört grup tanımlanmıştır. Yapılan
çalışmalarda histopatolojik sınıflama, normal g...
Aim
Amyloid A amyloidosis is a rare complication of chronic inflammatory conditions. Most patients with amyloid A amyloidosis present with nephropathy and it leads to renal failure and death. We studied clinical characteristics and survival in patients with amyloid A amyloidosis.
Methods:
A total of 81 patients (51 males, 30 females) with renal bi...
A amiloidose AA é uma complicação rara de condições inflamatórias crônicas. A maior parte dos pacientes com amiloidose AA apresenta nefropatia, que leva à insuficiência renal e à morte. Estudaram‐se as características clínicas e a sobrevida em pacientes com amiloidose AA.
Background/Purpose: Glomerulonephritis is among the most important group of diseases causing end-stage renal disease (ESRD). The prevalence of glomerulonephritis varies depending on age, sex, geographical features, etc. In the present study, we evaluated the clinical and laboratory parameters of patients who underwent renal biopsy.
Methods: In this...
Aim: Focal segmental glomerulosclerosis (FSGS) is one of the most common glomerulonephritis (GNP) worldwide. Despite treatment, it may progress to end-stage renal disease. In the present study, we compared clinical and histopathological data on FSGS with primary and secondary GNP retrospectively.
Methods: We retrospectively analyzed data on clinica...
Objective: Procalcitonin (PCT), C-Reactive Protein, serum amyloid A (SAA) and serum cholesterol values are early markers for inflammation, infection and malnutrition. In development acute kidney injury (AKI) infection, oral intake disorders, dehydratation and malnutrition
In this study, pregnant kidney recipients datas who were followed in our center were evaluated.
This study aimed to investigate the relationship between kidney biopsy findings, organ involvement and mortality in patients with AA amyloidosis.
Introduction and Aims: Arterial stiffness is known to be associated with adverse cardiovascularoutcomes and increased mortality in the general population. Early arterial stiffness has been shown in autosomal dominant polycystic kidney disease (ADPKD) patients with preserved renal function. However, according to our knowledge, there is no prospectiv...