Yasuko Isoe

Yasuko Isoe
Harvard University | Harvard · Department of Molecular and Cell Biology

Master of Science

About

8
Publications
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144
Citations

Publications

Publications (8)
Chapter
Zebrafish (Danio rerio) and medaka fish (Oryzias latipes) are popular vertebrate models for various biology fields. Medaka fish have recently attracted attention in the field of social neuroscience due to some of their unique advantages. First, medaka fish females have an extremely short ovarian cycle (24 h), which allows one to obtain a large numb...
Article
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Adult medaka fish (Oryzias latipes) exhibit complex social behaviors that depend mainly on visual cues from conspecifics. The ontogeny of visually-mediated social behaviors from larval/juvenile to adult medaka fish, however, is unknown. In the present study, we established a simple behavioral paradigm to evaluate the swimming proximity to conspecif...
Article
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Social familiarity affects mating preference among various vertebrates. Here, we show that visual contact of a potential mating partner before mating (visual familiarization) enhances female preference for the familiarized male, but not for an unfamiliarized male, in medaka fish. Terminal-nerve gonadotropin-releasing hormone 3 (TN-GnRH3) neurons, a...
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Full-text available
Genetic mosaic techniques have been used to visualize and/or genetically modify a neuronal subpopulation within complex neural circuits in various animals. Neural populations available for mosaic analysis, however, are limited in the vertebrate brain. To establish methodology to genetically manipulate neural circuits in medaka, we first created two...
Article
Tumor suppressor p53 negatively regulates self-renewal of neural stem cells in the adult murine brain. Here, we report that the p53 null mutation in medaka fish (Oryzias latipes) suppressed neurogenesis in the telencephalon, independent of cell death. By using 5-bromo-29-deoxyuridine (BrdU) immunohistochemistry, we identified 18 proliferation zones...

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