Yasuaki Mizushima

Yasuaki Mizushima
Osaka Police Hospital | OPH · Department of Emergency medicine

MD, PhD

About

63
Publications
9,923
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1,098
Citations
Citations since 2016
16 Research Items
340 Citations
201620172018201920202021202201020304050
201620172018201920202021202201020304050
201620172018201920202021202201020304050
201620172018201920202021202201020304050
Introduction
Additional affiliations
January 2000 - December 2012
Osaka Prefecture Senshu Critical Care Medical Center
Osaka Prefecture Senshu Critical Care Medical Center

Publications

Publications (63)
Article
Full-text available
Aim The quick Sequential Organ Failure Assessment (qSOFA) was proposed for use as a simple screening tool for sepsis. In this study, we evaluated the relationship between the prehospital use of qSOFA and prognosis in patients with sepsis or suspected sepsis using the population-based Osaka Emergency Information Research Intelligent Operation Networ...
Article
Full-text available
Background Air in the venous system may cause vascular air embolism, which is a potentially life-threatening event. The presence of air in venous system after basilar skull fracture is very rare. Case presentation A 77-year-old man fell from a truck bed and suffered head and neck trauma. On hospital arrival, his consciousness was clear and his vit...
Preprint
Full-text available
Background In 2016, the quick Sequential Organ Failure Assessment (qSOFA) was proposed for use as a simple screening tool for sepsis, with sepsis suspected at a score ≥ 2 points. In this study, we evaluated the effectiveness of prehospital qSOFA for predicting prognosis in patients with sepsis or suspected sepsis using the population-based Osaka Em...
Article
Full-text available
The impact of time of day or day of week on the survival of emergency trauma patients is still controversial. The purpose of this study was to evaluate the outcomes of these patients according to time of day or day of week of emergency admission by using data from the nationwide Japan Trauma Data Bank (JTDB).This study enrolled 236,698 patients reg...
Article
Full-text available
The blood lactate level is used to guide the management of trauma patients with circulatory disturbance. We hypothesized that blood lactate levels at the scene (Lac scene) could improve the prediction for immediate interventions for hemorrhage. We prospectively measured blood lactate levels and assessed retrospectively in 435 trauma patients both a...
Article
Full-text available
Purpose: Lumbar vertebral fracture (LVF) infrequently produces massive retroperitoneal hematoma (RPH). This study aimed to systematically review the clinical and radiographic characteristics of RPH resulting from LVF. Methods: For 193 consecutive patients having LVF who underwent computed tomography (CT), demographic data, physiological conditio...
Article
Introduction: Foreign body airway obstruction (FBAO) is a common medical emergency; however, few studies of life-threatening FBAO have been reported and no standard classification system is available. Methods: We retrospectively evaluated patients who presented to the emergency departments of two hospitals and were diagnosed with FBAO. The prima...
Article
Full-text available
Background Foreign body airway obstruction is a significant public health issue around the world. Mochi, a traditional sticky rice cake in Japan, has gained popularity in many countries including the USA. However, the associated aspiration danger has not yet been well recognized. Case presentation We describe three cases of foreign body airway obs...
Article
Full-text available
Background: A sudden shortage of physician resources due to overwhelming patient needs can affect the quality of care in the emergency department (ED). Developing effective response strategies remains a challenging research area. We created a novel system using information and communication technology (ICT) to respond to a sudden shortage, and tes...
Article
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Hereditary angioedema (HAE) with deficiency of C1 inhibitor (C1-INH) is an autosomal-dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The objective is to study the incidence of HAE among patients who visit the emergency department. This was a 3-year prospective observational screening study involving...
Article
Full-text available
Background Systemic immune response to injury plays a key role in the pathophysiological mechanism of blunt trauma. We tested the hypothesis that increased blood interleukin-6 (IL-6) levels of blunt trauma patients on emergency department (ED) arrival are associated with poor clinical outcomes, and investigated the utility of rapid measurement of t...
Article
Objective: Physiological parameters are crucial for the caring of trauma patients. There is a significant loss of prehospital vital signs data of patients during handover between prehospital and in-hospital teams. Effective strategies for reducing the loss remain a challenging research area. We tested whether the newly developed electronic automat...
Article
Full-text available
Background: Bicycle accidents are one of the major causes of unintentional traumatic injury in childhood. The purpose of this study was to examine characteristics and risks of handlebar injury in childhood. Methods: We conducted a more than 5-year retrospective survey of patients under 15 years of age with bicycle-related injuries admitted to ei...
Article
Full-text available
CaseA 30-year-old male involved in a traffic accident was brought to our hospital. He was in shock with a rigid abdomen, and a computed tomography scan showed severe pancreatoduodenal injury. He was successfully treated with damage control surgery consisting of peripancreatic packing at the initial surgery followed by a two-stage pancreaticoduodene...
Article
AimThe aim of this study was to determine whether the traditional criteria of chest tube output are useful indicators for urgent thoracotomy in patients with blunt chest trauma.Methods Data were collected retrospectively from our trauma registry of 542 blunt chest trauma patients (Chest Abbreviated Injury Scale score of 3 or greater) over a 10-year...
Article
Full-text available
We present a case of a 30-year-old postpartum woman who delivered by caesarean section at 34 weeks. On postoperative day 9, she was admitted to our hospital in shock. Emergency abdominal surgery was performed. Massive purulent ascites collected in the abdominal cavity and was associated with intestinal necrosis, which extended from the ascending co...
Article
Objectives Whether sex affects the mortality of trauma patients remains unknown. The hypothesis of this study was that sex was associated with altered mortality rates in trauma.MethodsA retrospective review of trauma patients’ records in the Japan Trauma Data Bank was conducted (n = 80,813) from 185 major emergency hospitals across Japan. The prima...
Article
Hereditary angioedema (HAE) is a rare genetic disease caused by a deficiency of functional C1 esterase inhibitor that causes swelling attacks in various body tissues. We hereby report a case of out-of-hospital cardiac arrest due to airway obstruction in HAE. Cutaneous swelling and abdominal pain attacks caused by gastrointestinal wall swelling are...
Article
An 89-year-old woman was transferred to our hospital following a diagnosis of rectal perforation 3 h previously. Damage control strategy (DCS) was adopted because she was in a state of shock on arrival (HR 106/min, BP 67/42 mmHg, RR 42/min, APACHE-II 32). On day 1 of admission, the perforated segment of the rectum was resected, and a temporary abdo...
Article
Full-text available
This study aimed to exhaustively examine associations between prehospital variables and emergency care resource needs among blunt trauma patients. The study included blunt trauma patients aged 15 years or older who were admitted to a tertiary care medical center in Osaka, Japan, from January 2005 to December 2009. The primary end point was a compos...
Article
Tachycardia is an important early sign of shock in trauma. Although the base deficit (BD) and lactate are indicative of hypoperfusion and known to predict mortality, some cases show a discrepancy between heart rate (HR) and BD or lactate; such cases have poor prognosis. The objective of this study was to examine whether lack of tachycardia after hy...
Article
Although damage control surgery (DCS) is a standard strategy for patients with severe abdominal trauma, this strategy is also extremely useful for patients with acute abdomen. Temporary abdominal closure is frequently performed in DCS, and in the present study, we preferentially selected vacuum packing closure (VPC) for temporary abdominal closure...
Article
Background: Although various trauma triage protocols have been developed to reduce undertriage with acceptable overtriage, risk factors for undertriage have rarely been examined. The objective of this study was to determine factors that can predict undertriage. Study Design: The study involved blunt trauma patients aged >= 15 years admitted to a cr...
Article
This study sought to define hemorrhagic shock from blood pressure and heart rate and then to provide a treatment policy based on response to initial fluid therapy. This was a prospective clinical observational study conducted in eight hospitals. Subjects were consecutive patients with trauma who met any of the field triage conditions proposed by th...
Article
経眼窩的穿通外傷では,多彩な合併損傷を来すことがあり,慎重な対応が必要である。今回我々は,下垂体一次損傷及び外傷性内頸動脈瘤を合併した経眼窩的穿通外傷の1例を経験したので報告する。症例は53歳の女性。自宅の庭で転倒した際に,植木の枝による左眼窩部杙創を来した。来院時左眼の失明と軽度意識障害が認められ,頭部CTでは左眼外側より刺入した異物が経眼窩的にトルコ鞍前壁に達していたが,明らかな脳実質の損傷は認められなかった。脳血管造影で左内頸動脈海綿静脈洞部に軽度の壁不整を認めた。第2病日に開頭による異物除去を施行した。術中尿崩症を認め,バソプレッシン投与を要した。MRIのT1強調画像で下垂体左側に腫大と異常信号を認め,下垂体損傷が示唆された。第7病日の脳血管造影検査では,左内頸動脈に動脈瘤の形成を認...
Article
In trauma patients, elevated body temperature is a common and noninfective procedure soon after injury. We hypothesized that the absence of this febrile response is associated with failure to meet metabolic demands and results in adverse outcomes. We collected retrospective data of 253 consecutive trauma patients admitted to the intensive care unit...
Article
鈍的脳血管損傷は欧米ではその多くが頸部脳血管に発生し,その頻度は全鈍的外傷の約 1 %前後,また椎骨動脈損傷(VAI)では25%,内頸動脈損傷(CAI)では50%もの高率に二次的脳卒中が発生すると報告されている。一方,頸部脳血管損傷の本邦での報告は少なく,頻度や治療などの点で一定のコンセンサスが得られていない。我々はこうした病態に対して積極的に血管内治療を導入して対処してきたが,今回鈍的頸部脳血管損傷の頻度・危険因子及び治療戦略における血管内治療の意義について検討した。2001年10月~2007年 9 月の期間に搬送された鈍的外傷患者1,405例を対象とし頸部脳血管損傷例につき調査した。その結果13例(0.93%),17血管の頸部脳血管損傷が認められた。損傷血管の内訳はVA I 13,CAI...
Article
Introduction Major intrahepatic bile duct damage as a result of severe blunt liver trauma is relatively uncommon; complications include bile fistulae, bilomas, bile peritonitis and sepsis. Management of these complications has evolved in the past few years, but very few reports have identified the best treatment. Most authorities recommend operativ...
Article
Full-text available
Blunt duodenal injury in children is uncommon and diagnosis is often delayed because of its retroperitoneal location. Both diagnosis and treatment are difficult. We report the case of a 2-year-old boy whose trauma injury was not reported for 5 days. His vital signs were stable, but he was vomiting bile-stained fluid and his stools were white. The t...
Article
A case of intraventricular hemorrhage caused by an Al perforating artery aneurysm was reported. A fifty-five year-old female without any hereditary background or infections had collapsed at work, become comatose, and was transferred to our hospital. Computed tomography showed a massive intraventricular hematoma, and subsequent angiography revealed...
Article
The Advanced Trauma Life Support guidelines recommend an initial rapid infusion of fluid (1-2 L) in trauma and hemorrhage victims as a diagnostic procedure to aid treatment decisions. Although patient response to initial fluid resuscitation is the key to determining therapeutic strategies, the appropriate rate of infusion is not clearly defined. Ni...
Article
The purpose of this study was to reevaluate extension of traumatic retroperitoneal hematoma (RH) and related management strategies in light of the new concept of retroperitoneal fascias as interfascial planes communicating with three compartments. Diagnostic computed tomographic images of 169 patients with traumatic RH treated between 1997 and 2003...
Article
Effective hepatic blood flow (EHBF) is thought to reflect splanchnic perfusion and the metabolic state of the liver. This study was conducted to examine the relationship between cardiac output (CO) and EHBF using pulse dye-densitometry (PDD) in nonseptic and septic patients, and to assess the prognostic value of this relationship. The subjects were...
Article
The Great Hanshin-Awaji earthquake caused many people to develop crush syndrome. Analysis of these patients revealed that the severity is not related to their hemodynamics but to hematocrit, base deficits, and potassium concentrations soon after their extrications. In the disaster site, these parameters can only be measured using whole-blood sample...
Article
To determine whether female sex steroids have any salutary effects on the depressed cardiovascular and hepatocellular functions following trauma and hemorrhage in male animals. Studies indicate that gender difference exists in the immune and cardiovascular responses to trauma-hemorrhage, and that male sex steroids appear to be responsible for produ...
Article
Although it is well known that pulmonary parenchymal injury impairs oxygenation, the relationship between hypoxemia and volume of the contused lung after blunt chest trauma remains unknown. We studied 23 blunt chest trauma patients who underwent thoracic computed tomography (CT) within 24 hours after admission and also underwent follow-up CT at 1-w...
Article
Rewarming the body to 37 degrees C during resuscitation following trauma-hemorrhage has salutary effects on cardiovascular and hepatocellular functions. Male rats underwent laparotomy (trauma induced) and were then bled to and maintained at a mean arterial pressure of 40 mm Hg until 40% of the maximum shed blood volume was returned in the form of R...
Article
Full-text available
Although studies have shown that induction of the heat shock proteins (HSPs), such as HSP-70, has various beneficial effects after ischemia-reperfusion, it remains unknown whether prior induction of HSP-70 has any salutary effects on cardiovascular and hepatocellular functions after trauma-hemorrhage and resuscitation. Male rats were exposed to hea...
Article
Although hypothermia often occurs after trauma and has protective effects during ischemia and organ preservation, it remains unknown whether maintenance of hypothermia or restoring the body temperature to normothermia during resuscitation has any deleterious or beneficial effects on heart performance and organ blood flow after trauma-hemorrhage. Ma...
Article
The objective of this study was to provide an overview of the morbidity and mortality of hospitalized patients during the Hanshin-Awaji earthquake. Medical records of 6,107 patients admitted to 95 hospitals (48 affected hospitals within the disaster area and 47 back-up hospitals in the surrounding area) during the initial 15 days after the earthqua...
Article
This study was undertaken to define the factors that affected the final outcome of trauma patients in the Hanshin-Awaji earthquake. Medical records of patients admitted to 95 hospitals within or surrounding the affected area during the first 15 days after the quake were reviewed. There were 2,702 traumatized patients. One-third of the patients were...
Article
Crush syndrome is a form of traumatic rhabdomyolysis characterized by systemic involvement, in which acute renal failure is potentially life-threatening. Clinical and laboratory data of 14 crush-syndrome patients transferred to a tertiary emergency department after the Hanshin-Awaji earthquake were analyzed. The patients were buried under collapsed...
Article
Background: Crush syndrome is a form of traumatic rhabdomyolysis characterized by systemic involvement, in which acute renal failure is potentially life-threatening. Methods: Clinical and laboratory data of 14 crush-syndrome patients transferred to a tertiary emergency department after the Hanshin-Awaji earthquake were analyzed. The patients were b...
Article
Background: Crush syndrome is a form of traumatic rhabdomyolysis characterized by systemic involvement, in which acute renal failure is potentially life-threatening. Methods: Clinical and laboratory data of 14 crush-syndrome patients transferred to a tertiary emergency department after the Hanshin-Awaji earthquake were analyzed, The patients were b...
Article
A 37-year-old pregnant woman at 35 weeks gestation was admitted to the OB-GYN service because of fever and sore throat. During hospitalization, she underwent artificial abortion because of fetal death. Since renal failure developed in addition to fever and sore throat, she was transferred to our hospital. After she receiving parenteral fluids and d...

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