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6
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Introduction
Additional affiliations
September 2022 - present
Institute for Stroke and Dementia Research (ISD)
Position
- PhD Student
Publications
Publications (6)
Background:
Hypertensive nephropathy (HN) is a high burden disorder and a leading cause of end-stage renal disorder. In spite of huge investigations, the underlying mechanisms are yet largely unknown. Systems biology is a promising approach to provide a comprehensive insight towards this complex disorder.
Methods:
Protein expression profiles of...
Motivation:
The recent availability of omics data allows the construction of holistic maps of interactions between numerous role-playing biomolecules. However, these networks are often static, ignoring the dynamic behavior of biological processes. On the other hand, dynamic models are commonly constructed on small scales. Hence, the construction o...
Background:
Diabetic nephropathy (DN) which refers to the cases with biopsy proven kidney lesions, is one of the main complications of diabetes all around the world; however, the underlying biological changes causing DN remain to be understood. Studying the alterations in gene expression profiles could give a holistic view of the molecular pathoge...
Background: Diabetic nephropathy (DN) which refers to the cases with biopsy proven kidney lesions, is one of the main complications of diabetes all around the world; However, the underlying biological changes causing DN remain to be understood. Studying the alterations in gene expression profiles could give a holistic view of the molecular pathogen...
Background
Modern medicine is equipped with huge amounts of big biological datasets and a wide range of computational methods to understand the molecular events underlying complex disorders. The recent availability of omics data allows a holistic view towards the interactions of various biomolecule types. However, the constructed maps are static, i...
Background
Hypertensive nephropathy (HN) is a high burden disorder and a leading cause of end-stage renal disorder. In spite of huge investigations, the underlying mechanisms are yet largely unknown. Systems biology is a promising approach to provide a comprehensive insight towards this complex disorder.
Methods
Protein expression profiles of kidn...