Yasemin Yavuz

• Ankara University

Purpose Adolescent Idiopathic Scoliosis negatively impacts chest wall development. Bracing and fusion surgery have shown varied effects on pulmonary outcomes. Vertebral Body Tethering presents a growth-sparing alternative that might mitigate these effects by reducing biomechanical disruptions. Aim was to evaluate changes in pulmonary functions duri...

Purpose Appendicular skeleton markers are commonly used for maturity assessment for Adolescent Idiopathic Scoliosis (AIS) patients. Traditionally, Risser has been a standard skeletal maturity assessment method. More recently, Sanders classification (SSMS), as a more comprehensive system, became popular, especially in decision-making for Vertebral B...

Objective Early-Onset Scoliosis Self-Report Questionnaire (EOSQ-SELF) is a recently developed self-reported questionnaire based on the widely adopted Early-Onset Scoliosis Questionnaire and evaluates health-related quality of life in children with early-onset scoliosis over 8 years of age. To date, the questionnaire does not have a validated versio...

Background EOSQ-24 is a parent proxy questionnaire designed to assess the health-related quality of life (HRQoL) of early-onset scoliosis (EOS) patients during their childhood years. EOSQ-SELF, a novel self-reported questionnaire, assesses HRQoL in older children (>8 y) and adolescents. So far, the same group of EOS patients has not been evaluated...

Objectives: Cardiopulmonary bypass cause microcirculatory alterations. Near infrared spectroscopic measurement of tissue oxygen saturation and vascular occlusion test are novel technologies for assessing the microcirculatory function of peripheral tissue specifically in patients undergoing cardiac surgery with cardiopulmonary bypass.Our study aime...

In response to sagittal malalignment, compensatory spinal and lower extremity mechanisms are recruited. Thoracolumbar realignment surgery has been shown to yield reciprocal changes in these compensations. Thus, whole-body radiographic assessment has come to the fore. This study aimed to evaluate the relationship between spinopelvic parameters and l...

Background Context There remains significant variability in the use of postoperative opioids. On one end, it is proven that appropriate pain control is a critical aspect of patient management; on the other end, past few decades have been associated with major increases in opioid-related overdoses and addiction treatment. We hypothesized that severa...

BACKGROUND CONTEXT There is a paucity of information on mid- to long-term clinical and radiographic outcomes of VBT surgery. PURPOSE The aim of the study was to report mid-term outcomes of thoracoscopic thoracic-only anterior VBT surgery. STUDY DESIGN/SETTING Retrospective analysis of prospectively collected data. PATIENT SAMPLE Twenty-three (22...

Introduction This study aimed to analyse the results of paediatric aortic valve repairs in our institution. Method The data of 57 patients under 18 years of age who underwent aortic valve repair between 2014 and 2019 were retrospectively analysed. Early postoperative reoperation and hospital mortality rates were evaluated based on the ages of the...

This study aimed to address the role of various inflammation-related blood indices for the assessment of in-hospital outcomes in subjects undergoing Glenn procedure. Subjects who underwent the Glenn procedure for hypoplastic left heart syndrome were analysed retrospectively. Subjects were divided into two groups: Group 1 consisted of 78 patients wh...

Background: This study aimed to examine the effects of theophylline use in preventing renal dysfunction in patients undergoing CHD surgery. Methods: A total of 94 patients aged 1-60 months were included in the study. Patients in the theophylline group were enrolled according to a pre-defined protocol for treatment administration, while controls...

Objective The aim of this study was to evaluate the relationship between preoperative nutritional status and the postoperative clinical outcomes of cardiac surgery performed in children with congenital heart disease (CHD). Methods This was a prospective observational study conducted between March 2019–2020, which included 80 patients with CHD. Pre...

Introduction In cardiac surgery,anesthesia induction causes significant haemodynamic changes. However, haemodynamic management routinely uses blood pressure and cardiac output targets, and this is supported by blood analyses but for this rarely employs microvascular monitoring [1]. However, macrohaemodynamics management following cardiac surgery is...

BACKGROUND CONTEXT Disc health after various growth modulation techniques have been assessed in animal models, and tethering was claimed to prevent degeneration due to its less rigid nature compared to other growth-friendly techniques. Yet, the results of animal studies wherein tethering is applied on healthy spines to create a deformity cannot be...

BACKGROUND CONTEXT There is a paucity of information on clinical and radiographical outcomes of vertebral body tethering (VBT) surgery. Current information is not yet strong enough to convince surgeons to include this surgical technique to their armamentarium. PURPOSE The aim of the study was to report clinical and radiographic outcomes of thoraco...

Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease. Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 mon...

Objectives: This study aims to investigate the relationship between anxiety levels and perceived caregiver burden in mothers of children who had undergone Congenital Heart Disease Surgery (CHDS) and who were followed up in the intensive care unit with the surgical type and clinical variables applied. Patients and Methods: The study was conducted wi...

Objectives: Extracorporeal membrane oxygenation (ECMO), whose use has increased with technological developments in pediatric heart surgery, is a life-saving treatment modality that is used in patients with cardiac or pulmonary insufficiency who are unresponsive to medical treatment. We investigated the effect of operation technique and cardiac morp...

Objectives: Infants and children with congenital heart disease may develop respiratory failure in association with cardiac surgery or as a result of heart disease. In fact, the postextubation period in this group of patients can be complex and the use of continuous positive airway pressure or non-invasive ventilation may be necessary if conventiona...

Introduction: The aim of this study was to evaluate the effects of intraoperative and postoperative theophyl- line infusion on inflammation in children who underwent open heart surgery with cardiopulmonary bypass (CPB) for congenital heart diseases. Patients and Methods: This randomized controlled study was carried out with 140 children who underwe...

Background: It is difficult to predict the complications and prognosis of ECMO, which is gaining widespread use in patients with pediatric surgery. Platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) are emerging inflammatory markers that can be calculated from complete blood count, which is a cheap and easily accessible la...

Background Context Vertebral body tethering (VBT), a flexible compression-based growth modulation technique, was claimed to prevent disc degeneration due to its less rigid nature compared to other growth-friendly techniques. Yet, the consequences of VBT surgery on discs and facet joints have not been precisely acknowledged. Purpose The purpose of...

The most common CHD in the adult patient population is an atrial septal defect due to its asymptomatic nature in early life. However, when diagnosis and treatment are delayed, pulmonary arterial hypertension may develop as a long-term complication, sometimes before adulthood. The presence of PAH adversely affects the results of surgical treatment a...

Stellate ganglion block is used as an adjunctive therapy method in various painful situations mediated by the sympathetic nervous system, especially complex regional pain syndrome. The process after medical and stellate ganglion block treatment in a 66-year-old female patient diagnosed with hypertension, ischemic heart disease, heart failure, Rayna...

Study design: Retrospective analysis of prospectively collected dataObjective. To report the follow-up curve behaviors in different Sanders staging groups. Summary of background data: Vertebral Body Tethering (VBT) is a growth modulation technique that allows gradual spontaneous follow-up curve correction as the patient grows. There is a lack of...

Objectives:The aim of this study was to determine whether there would be an increase in the need for intra-operative neuromuscular blocker consumption due to better preservation of body temperature in low flow anesthesia. In this study, the effects of minimal, low and medium flow anesthesia on intra-operative neuromuscular blocker consumption were...

Objectives:In this study, it was aimed to adapt the 17-item (37 sub-items) STROCSS (Strengthening the Reporting of Cohort Studies in Surgery) criteria published in 2017 by a group of experts to improve the reporting quality of cohort studies in the surgical field and to establish a standard.Materials and Methods:STROCSS criteria were translated to...

Introduction The microvascular dysfunction after cardiac surgery with cardiopulmonary bypass (CPB) and impaired tissue oxygen saturation (StO2) have been associated with adverse patient outcome.(1)Measuring StO2 using near-infrared spectroscopy (NIRS) with a reproducible vascular occlusion test (VOT) has shown to be a noninvasive method suitable fo...

Background Hypoplastic left heart syndrome is a lethal congenital heart malformation when untreated resulting in a 95% mortality in the first month of life. In this study, we aimed to investigate the newly introduced inflammatory biomarker, neutrophil–lymphocyte ratio, as a mortality predictor in postoperative hypoplastic left heart syndrome patien...

This study describes the R package kaphom, which is developed in order to easily perform four different homogeneity tests recommended to be used to test the homogeneity of intra-class kappa statistics, from multiple independent studies or a single stratified study. R package kaphom, contains Fleiss, Donner Goodness of Fit, Likelihood Score and Modi...

Objective: The aim of this study was to compare mandibular index values, including the mandibular cortical index (MCI), mental index (MI), and panoramic mandibular index (PMI), determined on the basis of cone beam computed tomography (CBCT) and panoramic reconstructed (PR) images. Study design: PR and CBCT images of 182 patients were retrospecti...

Betimleyici Çeviribilim temelli bu çalışmanın amacı, kültüre özgü bir öge olarak değerlendirilen çevre/doğa bilgisi içeren sözcüklerin kültürlerarası aktarımı sırasında geliştirilen çeviri yöntemlerinin dağılımlarını niceliksel verilerle tarihsel olarak belirlemek ve kültür ögelerinin çevrilmesi açısından çocuk edebiyatı kapsamında öncül bir yöntem...

Background context: Pelvic Tilt (PT) is used as an indicator of pelvic version with increased values indicating retroversion and disability. The concept of using PT solely as an absolute numerical value can be misleading, especially for the patients with Pelvic Incidence (PI) values near the upper and lower normal limits. Relative Pelvic Version (...

OBJECTIVE The subtraction of lumbar lordosis (LL) from the pelvic incidence (PI) offers an estimate of the LL required for a given PI value. Relative LL (RLL) and the lordosis distribution index (LDI) are PI-based individualized measures. RLL quantifies the magnitude of lordosis relative to the ideal lordosis as defined by the magnitude of PI. LDI...

Background: Postoperative mechanical ventilation is required in patients undergoing congenital heart surgery. However, the duration of mechanical ventilation may be extended as a result in some patients. Inflammation is a normal and expected process following surgery and the intensive care process. However, increased and prolonged inflammation incr...

Background: The restoration of normal sagittal alignment is a critical goal in adult spinal deformity surgery to achieve favorable outcomes and prevent mechanical complications. Schwab sagittal modifiers have been accepted as targets for appropriate alignment, but addressing these targets does not always prevent high mechanical complication or rev...

This study aims to address a simultaneous comparison of sensitivity and specificity of two different tests by taking into consideration of prevalence and clinical significance level of the tests under the condition that the result of the gold standard test is known. The proposed method involves the point and interval estimation of the weighted mean...

Objective: The aim of this study was to analyze the impact of treatment complications on outcomes in adult spinal deformity (ASD) using a decision analysis (DA) model. Methods: The study included 535 ASD patients (371 with non-surgical (NS) and 164 with surgical (S) treatment) from an international multicentre database of ASD patients. DA was st...

Objective Acute kidney injury after cardiac surgery is associated with mortality and morbidity. Therefore, strategies to prevent acute kidney injury are very important. The aim of this placebo-controlled randomized double-blind study was to compare the prophylactic efficacy of N-Acetylcysteine and dopamine administration in patients with pre-existi...

The purpose of this study was to compare the properties of a number of novel and a traditional measure to evaluate the predictive performance of a new marker. For that purpose, we analyzed data, which contains age, gender, hypertension, hyperlipidemia, and smoking and total cholesterol/high density lipoprotein as the clinical risk factors for the i...

Objective: Markers which are used for classification into two groups, such as patient / healthy, benign/malignant or prediction of optimal cut off value for diagnostic test and evaluating the performance of diagnostic tests is evaluated by Receiver Operating Characteristic (ROC) curve in the diagnostic test researches. In classification accuracy re...

Objective: Determine socioeconomic characteristics, prenatal care and maternal risk factors and to reveal the impact on newborn, in mothers who gave birth. Materials and Methods: A case-control study comparing the mothers whose babies admitted and whose babies not admitted to neonatal intensive care unit of a University Hospital. 200 women as a cas...

Objective: Determine socioeconomic characteristics, prenatal care and maternal risk factors and to reveal the impact on newborn, in mothers who gave birth. Materials and Methods: A case-control study comparing the mothers whose babies admitted and whose babies not admitted to neonatal intensive care unit of a University Hospital. 200 women as a cas...

Background Adult spinal deformity (ASD) is a major public health problem. There are pros and cons of the available treatment alternatives (surgical or non-surgical) and it had been difficult to identify the best treatment modality. Aim To construct a statistical DA model to identify the optimum overall treatment in ASD. Methods From an internationa...

The modelling of time-series and the evaluation of forecasts for the future: the case of the number of persons per physician in turkey between 1928 and 2010

Objective: To assess the in vitro diagnostic ability of CBCT images using 7 different display types in the detection of recurrent caries. Methods: Our study comprised 128 extracted human premolar and molar teeth. Eight (8) groups each containing 16 teeth were obtained as follows: 1: Black Class I (Occlusal) amalgam filling without caries; 2: Bla...

Introduction Treatment of adult spinal deformity (ASD) is known to be associated with a fairly high rate of complications whereas the impact of these complications on treatment outcomes is less well known. Aim of this study is to analyze the impact of treatment complications on outcomes in ASD using a decision analysis (DA) model. Material and Met...

Introduction Adult spinal deformity (ASD) is a major public health problem. There are pros and cons of the available treatment alternatives (surgical or non-surgical) and it had been difficult to identify the best treatment modality. Aim of this study is to construct a statistical decision analysis (DA) model to identify the optimum overall treatme...

The biological activity of a substance can be investigated through a series of experiments done with the increased or decreased dosage of it. One of the purposes of such studies is to determine the trend of responses based on dosage. In studies carried out for this purpose, appropriate sample size has an indisputable influence on the reliability of...

Objectives: Health professionals are very important for improving the health status of the society and maintaining a healthy life. The aim of the present study is to model the number of persons per physician via Box-Jenkins and exponential smoothing methods and trend models, to compare these models, and to make estimations for the future. ARIMA or...

In this study, an attempt was made to determine the degrees of bias in particular sampling sizes and methods. The aim of the study was to determine deviations from the median, the mean, and the standard deviation (SD) in different sample sizes and at different censoring rates for log-normal, exponential, and Weibull distributions in the case of ful...

Introduction Scimitar syndrome is a complex congenital disorder affecting the right lung. Diaphragma paralysis is one of the important causes of morbidity and mortality in congenital heart surgery especially under 2 years of age in pediatric cardiac surgery. Phrenic nerve injury is a complication which occurs after cardiothoracic surgery and causes...

Background: Previous studies demonstrated the adult spinal deformity (ASD) population is heterogeneous. Multiple parameters may affect health-related quality of life (HRQL). Aim: To understand the ranking of parameters affecting HRQL in ASD using multiple regression analysis. Patients and methods: A total of 483 patients enrolled in a prospect...

The aim of this study was to evaluate the additional diagnostic value of "inversion recovery" single-shot fast-spin echo (IR-SSFSE) sequence using the inversion time at the null point for hepatic hemangiomas as a supplement to standard T2-weighted (T2W) magnetic resonance imaging for the distinction of hemangiomas and cysts. A total of 228 lesions...

Early-onset scoliosis (EOS) can have negative effects on the developing thorax, lungs, and quality of life in general. Children with EOS can face various health problems and require recurring hospitalization and surgeries. Radiographic parameters are insufficient to evaluate the severity and efficacy of treatment in EOS. Early-onset Scoliosis Quest...

Abstract The use of joint models that are capable of handling different data types is becoming increasingly popular in biopharmaceutical practice. Evaluation of various statistical techniques that have been developed for mixed data in simulated environments requires joint generation of multiple variables. In this article, we propose a unified frame...

The main purpose in all experimental designs is to take into account the factors that are considered likely to have an effect on the response variable emphasized, and to minimize the error of experiment in this way. Bread, which is the staple human food, cannot have any negative effect on human beings as long as it is produced by using suitable mat...

zet Bu çalışmanın birinci amacı, Halliday'in (Halliday, 1994; Halliday ve Matthiesen 2004) Dizgeci İşlevsel Dilbilgisi modeli çerçevesinde sözlü çeviri öğrencileri tarafından oluşturulan sözlü çeviri metinlerindeki kip kaydırmalarını çeviri türü, yönlülük ve metin türü açısından karşılaştırmalı olarak incelemektir. İkinci amaç, söz konusu kaydırmal...

Aim: The aim of this study is translate the STARD (The STAndards for Reporting of Diagnostic Accuracy) criteria which were developed in 2003 by a group of epidemiologists and biostatisticians in order to establish a standard for planning and reporting the results of the diagnostic accuracy studies. Materials and Design: The STARD criteria that were...

BACKROUND: In this study, a BOX-BEHNKEN design (BBD) of response surface methodology was used to investigate the effects of the amount of bran, the amount of yeast and the fermentation time on the amount of phytic acid in bread. The goal of first order factorial experiment is to identify the optimum levels of independent variables for the dependent...

The evaluation of renal function in patients with decompensated cirrhosis is important for prognosis, dosage assessment of potentially nephrotoxic drugs and recognition of changes in glomerular filtration rate (GFR) to decide paracentesis and diuretic therapy. Patients with many different disorders of hepatic function can present with various abnor...