Yannick Legré

Yannick Legré
OPERAS

MSc.IT

About

61
Publications
5,241
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
602
Citations
Introduction
Yannick is the secretary general of OPERAS Research Infrastructure. Formerly he was the director of EGI.eu between until end of 2019, worked for the French CNRS and held various senior positions in several SMEs. He holds a Master of Science in Information Technology (MScIT) and a degree in Law (LL.L). Yannick has been involved in 50+ projects in e-Infrastructures, healthcare, biomedical, biodiversity and environmental research.

Publications

Publications (61)
Poster
Full-text available
Data produced by biodiversity research projects that evaluate and monitor Good Environmental Status have a high potential for use by stakeholders involved in [marine] environmental management. The lack of specific scientific objectives, poor organizational logic, and a characteristically disorganized collection of information leads to a decentraliz...
Presentation
Full-text available
Data produced by biodiversity research projects that evaluate and monitor Good Environmental Status have a high potential for use by stakeholders involved in [marine] environmental management. The lack of specific scientific objectives, poor organizational logic, and a characteristically disorganized collection of information leads to a decentraliz...
Conference Paper
Environmental research infrastructures (RIs) support their respective research communities by integrating large-scale sensor/observation networks with data curation services, analytical tools and common operational policies. These RIs are developed as pillars of intra-and interdisciplinary research, however comprehension of the complex, pathologica...
Article
Full-text available
Growing use of cloud computing in clinical trials prompted the European Clinical Research Infrastructures Network, a European non-profit organisation established to support multinational clinical research, to organise a one-day workshop on the topic to clarify potential benefits and risks. The issues that arose in that workshop are summarised and i...
Article
Full-text available
With this paper, EGI proposes the Open Science Commons as a new approach to digital research, tackling policy challenges and embracing open science as a new paradigm for knowledge creation and collaboration. EGI invites organisations from the research landscape to join it in this journey to develop these concepts, and through them to advance the im...
Article
Full-text available
Grids have emerged as a promising technology to handle the data and compute intensive requirements of many application areas. Digital medical image processing is a promising application area for grids. Given the volume of data, the sensitivity of medical information, and the joint complexity of medical datasets and computations expected in clinical...
Article
Full-text available
The European ENVRI project (Common operations of Environmental Research Infrastructures) is addressing common ICT solutions for the research infrastructures as selected in the ESFRI Roadmap. More specifically, the project is looking for solutions that will assist interdisciplinary users who want to benefit from the data and other services of more t...
Conference Paper
Full-text available
Frontier environmental research increasingly depends on a wide range of data and advanced capabilities to process and analyse them. The ENVRI project, "Common Operations of Environmental Research infrastructures" is a collaboration in the ESFRI Environment Cluster, with support from ICT experts, to develop common e-science components and services f...
Article
Full-text available
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also off...
Article
Full-text available
A New Dawn for environmental data networks - Environment - "International Innovation is the leading global dissemination resource for the wider scientific, technology and research communities, dedicated to disseminating the latest science, research and technological innovations on a global level. More information and a complimentary subscription of...
Article
Full-text available
A New Dawn for environmental data networks - Environment - "International Innovation is the leading global dissemination resource for the wider scientific, technology and research communities, dedicated to disseminating the latest science, research and technological innovations on a global level. More information and a complimentary subscription of...
Article
Full-text available
Overview In this paper, we present the g-INFO (Grid-based International Network for Flu Observation) project that aims at running and connecting various bioinformatics programs, recognized for their accuracy and speed, to continuously reconstruct a robust phylogenetic tree from a set of sequences publicly available and daily updated for the sake of...
Article
Full-text available
In this paper, we introduce a portal for monitoring Influenza A on a grid-based system. Influenza A keeps on being a major threat to public health worldwide; especially if one virus can mutate itself so that it acquires the capacity for human to human transmission of H1N1 as well as the high death rate of H5N1. The existing g-INFO (Grid-based Infor...
Article
In this paper, we introduce a flexible workflow to monitor the evolution of the avian flu virus. Indeed, avian flu remains a major threat to public health worldwide if it acquires the capacity for human to human transmission. The monitoring of H5N1 requires many steps of data analysis. We present here a workflow that can automate this procedure or...
Article
Full-text available
The 2009 H1N1 outbreak has demonstrated that continuing vigilance, planning, and strong public health research capability are essential defenses against emerging health threats. Molecular epidemiology of influenza virus strains provides scientists with clues about the temporal and geographic evolution of the virus. In the present paper, researchers...
Article
Full-text available
Grid technologies have proven their capabilities to settle challenging problems of medical data access. The grid ability to access distributed databases in a secure and reliable way while preserving data ownership opened new perspectives in medical data sharing and disease surveillance. This paper focuses on the implementation challenges of grid-po...
Article
Neuroscience is increasingly making use of statistical and mathematical tools to extract information from images of biological tissues. Computational neuroimaging tools require substantial computational resources and the increasing availability of large image datasets will further enhance this need. Many efforts have been directed towards creating...
Article
Full-text available
IGI-Global Medical Information Science Discoveries Research Award 2009
Article
The SHARE(1) project (http://www.eu-share.org) was asked to identify the key developments needed to achieve wide adoption and deployment of HealthGrids throughout Europe. The project was asked to organise these as milestones on a road map, so that all technical advances, social actions, economic investments and ethical or legal initiatives necessar...
Article
Full-text available
Recent developments of grid services for secured distributed data management open new perspectives for disease surveillance. In this paper, we report on our initiative to develop a surveillance network for breast cancer in the Auvergne region. The network gathers cytopathology laboratories, structures in charge of cancer screening and institutes in...
Chapter
The principal goal of this chapter is to elucidate the future requirements of healthgrids if they are to become the infrastructure of choice for biomedical research and healthcare. These require ments take many forms, technical, organizational and economic, with initiatives required in the domains of ethical and legal regulation. Thus, particular o...
Chapter
Grid technologies and infrastructures can contribute to harnessing the full power of computer-aided image analysis into clinical research and practice. Given the volume of data, the sensitivity of medical information, and the joint complexity of medical datasets and computations expected in clinical practice, the challenge is to fill the gap betwee...
Article
Full-text available
The paper describes a platform developed for the secure management and analysis of medical data and images in a grid environment. Designed for telemedicine and built upon the EGEE gLite middleware and particularly the metadata catalogue AMGA as well as the GridSphere web portal, the platform provides to healthcare professionals the capacity to uplo...
Article
Full-text available
The HealthGrid White Paper was published at the third annual conference in Oxford in 2005. Starting from the conclusions of the White Paper, the EU funded SHARE project (http://www.eu-share.org) has aimed at identifying the most important steps and significant milestones towards wide deployment and adoption of healthgrids in Europe. The project has...
Article
à paraître dans"Book of abstracts"
Article
à paraître dans "Book of abstracts"
Article
Large scale grids for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale virtual docking within the framework of the WISDOM initiative against malaria and avian influenza requiring about 100 years of CPU on the EGEE, Auvergrid and TWGrid in...
Article
Full-text available
Secure, flexible and efficient storing and accessing digital medical data is one of the key elements for delivering successful telemedical systems. To this end grid technologies designed and developed over the recent years and grid infrastructures deployed with their use seem to provide an excellent opportunity for the creation of a powerful enviro...
Article
We present the 'HealthGrid' initiative and briefly review work carried out in various European healthgrid projects. We report on joint work with numerous European collaborators. Since the European Commission's Information Society Technologies programme funded the first gridbased health and medical projects, the HealthGrid movement has flourished in...
Article
Full-text available
This paper proposes a 10-year roadmap to achieve the goal to offer to healthcare professionals an environment created through the sharing of resources, in which heterogeneous and dispersed health data as well as applications can be accessed by all users as a tailored information providing system according to their authorisation and without loss of...
Article
Full-text available
We present the 'HealthGrid' initiative and review work carried out in various European projects. Since the European Commission's Information Society Technologies programme funded the first grid-based health and medical projects, the HealthGrid movement has flourished in Europe. Many projects have now been completed and 'Healthgrid' consulted a numb...
Article
Full-text available
WISDOM is an international initiative to enable a virtual screening pipeline on a grid infrastructure. Its first attempt was to deploy large scale in silico docking on a public grid infrastructure. Protein-ligand docking is about computing the binding energy of a protein target to a library of potential drugs using a scoring algorithm. Previous dep...
Article
Full-text available
Large-scale grid infrastructures for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale in silico docking within the framework of the WISDOM initiative against Malaria and Avian Flu requiring about 105 years of CPU on the EGEE, Auvergrid an...
Article
PCSV, présenté par N. Jacq, transparents sur site, pas de proceedings
Article
Full-text available
WISDOM stands for World-wide In Silico Docking On Malaria. First step toward enabling the in silico drug discovery pipeline on a grid infrastructure, this CPU consuming application generating large data flows was deployed successfully on EGEE, the largest grid infrastructure in the world, during the summer 2005. 46 million docking scores were compu...
Article
Full-text available
With the regular progress of technology and infrastructures, a growing number of grid applications are developed and deployed for life science and medical research. At the last HealthGrid conference in April 2005 in Oxford, many groups described successful usage of grids for compute intensive calculations. Very large scale deployment of a biomedica...
Conference Paper
Full-text available
Large scale grids for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale virtual docking within the framework of the WISDOM initiative against malaria and avian influenza requiring about 100 years of CPU on the EGEE, Auvergrid and TWGrid in...
Article
Full-text available
Grids have emerged as a promising technology to handle the data and compute intensive requirements of many application areas. Digital medical image processing is a promising application area for grids. Given the volume of data, the sensitivity of medical information, and the joint complexity of medical datasets and computations expected in clinical...
Conference Paper
Full-text available
Digital medical image processing is a promising application area for grids. Given the volume of data, the sensitivity of medical information, and the joint complexity of medical datasets and computations expected in clinical practice, the challenge is to fill the gap between the grid middleware and the requirements of clinical applications. The res...
Article
Full-text available
RUGBI is an industrial and academic project to design and deploy on top of existing technologies a computing grid offering a set of grid and bioinformatics services to analyse proteins. It aims to support life sciences SMEs for computing and storage, to deploy an interregional grid for bioinformatics and to create a biologists community in a grid e...
Article
Full-text available
Background: The training of local clinicians is the best way to raise the standard of medical knowledge in developing countries. This requires transferring skills, techniques and resources. Objectives: Grid technology opens new perspectives for preparation and follow-up of medical missions in developing countries as well as support to local medi...
Article
Background: The training of local clinicians is the best way to raise the standard of medical knowledge in developing countries. This requires transferring skills, techniques and resources. Objectives: Grid technology opens new perspectives for preparation and follow-up of medical missions in developing countries as well as support to local medical...
Article
Full-text available
The European 1ST DataGrid project was a pioneer in identifying the medical imaging field as an application domain that can benefit from Grid technologies. This paper describes how and for which purposes medical imaging applications can be Grid-enabled. Applications that have been deployed on the DataGrid testbed and middleware are described. They r...
Conference Paper
Full-text available
The deployment of biomedical applications in a grid environment has started about three years ago in several European projects and national initiatives. These applications have demonstrated that the grid paradigm was relevant to the needs of the biomedical community. They have also highlighted that this community had very specific requirements on m...
Article
Full-text available
Monte Carlo simulations are increasingly used in medical physics. In scintigraphic imaging these simulations are used to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantization. In radiotherapy-brachytherapy the goal is to evaluate accurately the dosimetry in compl...

Network

Cited By

Projects

Projects (2)