Yann Devos

Yann Devos
EFSA European Food Safety Authority | EFSA · SCER Unit

PhD

About

139
Publications
28,886
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2,557
Citations
Citations since 2017
55 Research Items
1272 Citations
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Publications

Publications (139)
Article
Full-text available
Abstract Genetically modified maize GA21 × T25 was developed by crossing to combine two single events: GA21 and T25. The GMO Panel previously assessed the two single maize events and did not identify safety concerns. No new data on the single maize events were identified that could lead to modification of the original conclusions on their safety. T...
Article
Background On 21–24 June 2022, the European Food Safety Authority, together with the European Centre for Disease Prevention and Control, the European Chemicals Agency, the European Environment Agency, the European Medicines Agency, and the Joint Research Centre of the European Commission, held the “ONE – Health, Environment & Society – Conference 2...
Article
Engineered gene drives, which bias their own inheritance to increase in frequency in target populations, are being developed to control mosquito malaria vectors. Such mosquitoes can belong to complexes of both vector and nonvector species that can produce fertile interspecific hybrids, making vertical gene drive transfer (VGDT) to sibling species b...
Article
The online publication is available at: https://efsa.onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2022.e200505
Article
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Teosinte, wild maize relatives originating from Mexico and Central America, emerged as a noxious agricultural weed in France and Spain. In 2016, the European Food Safety Authority (EFSA) issued a technical report that assessed the available scientific information on teosinte for its relevance for the environmental risk assessment (ERA) and risk man...
Chapter
Genetic modification has been used for over 20 years to produce genetically modified plants (GMPs) and derived food and feed products. Recent scientific developments in molecular and synthetic biology enable the (targeted) engineering of new generation GMPs, and are widening the spectrum of plant species and traits that can be modified. While exist...
Chapter
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This chapter aims to introduce the reader to the basic principles of environmental risk assessment of chemicals and highlights the usefulness of tiered approaches within weight of evidence approaches in relation to problem formulation i.e., data availability, time and resource availability. In silico models are then introduced and include quantitat...
Article
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The ability to engineer gene drives (genetic elements that bias their own inheritance) has sparked enthusiasm and concerns. Engineered gene drives could potentially be used to address long-standing challenges in the control of insect disease vectors, agricultural pests and invasive species, or help to rescue endangered species. However, risk concer...
Article
Risk assessors, risk managers, developers, potential applicants, and other stakeholders at many levels discuss the need for new or further risk assessment guidance for deliberate environmental releases of gene drive-modified organisms. However, preparing useful and practical guidance entails challenges, to which we offer recommendations based on ou...
Article
Full-text available
Potential future application of engineered gene drives (GDs), which bias their own inheritance and can spread genetic modifications in wild target populations, has sparked both enthusiasm and concern. Engineered GDs in insects could potentially be used to address long-standing challenges in control of disease vectors, agricultural pests and invasiv...
Article
Since 1998, genetically engineered Bt maize varieties expressing the insecticidal Cry1Ab protein (i.e. event MON 810) have been grown in the European Union (EU), mainly in Spain. These varieties confer resistance against the European and Mediterranean corn borer (ECB and MCB), which are the major lepidopteran maize pests in the EU, particularly in...
Article
Full-text available
Oilseed rape 73496 was developed to confer tolerance to the herbicidal active substance glyphosate through the expression of the glyphosate acetyltransferase protein GAT4621. The molecular characterisation data and bioinformatic analyses identify no issues requiring food/feed safety assessment. None of the identified differences between oilseed rap...
Article
The European Commission mandated EFSA to complement its original scientific opinion on soybean MON 87769 × MON 89788 (EFSA‐GMO‐NL‐2010‐85) considering additional information on the human nutritional assessment of refined bleached deodorised oil produced from the two‐event stack soybean (RBD GM‐oil). The assessment was mainly based on a replacement...
Article
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This publication is linked to the following EFSA Supporting Publications article: http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2021.EN-6443/full.
Article
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Synthetic Biology (SynBio) is an interdisciplinary field at the interface of engineering and biology aiming to develop new biological systems and impart new functions to living cells. EFSA has been asked by the European Commission to evaluate SynBio developments in agri-food with the aim of identifying the adequacy of existing guidelines for risk a...
Article
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Maize 1507 × MIR162 × MON810 × NK603 (four-event stack maize) was produced by conventional crossing to combine four single events: 1507, MIR162, MON810 and NK603. The GMO Panel previously assessed the four single events and six of the subcombinations and did not identify safety concerns. No new data on the single events or the six subcombinations t...
Technical Report
Full-text available
The European Food Safety Authority (EFSA) carried out an online public consultation to receive input from interested parties/persons on the draft scientific opinion on the adequacy and sufficiency evaluation of existing guidelines for the molecular characterisation (MC), environmental risk assessment (ERA) and post-market environmental monitoring (...
Article
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Advances in molecular and synthetic biology are enabling the engineering of gene drives in insects for disease vector/pest control. Engineered gene drives (that bias their own inheritance) can be designed either to suppress interbreeding target populations or modify them with a new genotype. Depending on the engineered gene drive system, theoretica...
Article
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Soybean DAS-8419-2 × DAS-44406-6 was developed to provide protection against certain lepidopteran pests and tolerance to 2,4-dichlorophenoxyacetic acid and other related phenoxy herbicides, and glyphosate- and glufosinate ammonium-containing herbicides. The Genetically Modified Organisms (GMO) Panel previously assessed the two single soybean events...
Article
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Abstract Maize MZIR098 was developed to confer tolerance to glufosinate‐ammonium‐containing herbicides and resistance to certain coleopteran pests. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositio...
Article
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Abstract Oilseed rape MS11 has been developed to confer male sterility and tolerance to glufosinate‐ammonium‐containing herbicides. Based on the information provided in the application and in line with the scope of application EFSA‐GMO‐BE‐2016‐138, the genetically modified organism (GMO) Panel concludes that the molecular characterisation data and...
Article
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Abstract Soybean MON 87705 × MON 87708 × MON 89788 (three‐event stack soybean) was produced by conventional crossing to combine three single soybean events: MON 87705, MON 87708 and MON 89788. This combination is intended to alter the fatty acid profile in the seed (in particular increasing the levels of oleic acid) and tolerance to glyphosate‐base...
Article
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Genetically modified plants (GMPs) intended for market release can be designed to induce “gene silencing” through RNA interference (RNAi). The European Food Safety Authority (EFSA) and other international risk assessment bodies/regulatory agencies have taken several actions to determine whether the existing risk assessment approaches for GMPs are a...
Article
Full-text available
Recent advances in molecular and synthetic biology are enabling the engineering of gene drives that spread genes of interest through interbreeding populations at a frequency greater than the rate expected by simple Mendelian inheritance. At present, insects represent the most likely cases of gene drive modified organisms for deliberate release into...
Article
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Abstract The scope of application EFSA‐GMO‐DE‐2012‐111 is for food and feed uses, import and processing of genetically modified (GM) soybean SYHT0H2 in the European Union. Soybean SYHT0H2 was developed to confer tolerance to the herbicidal active substances mesotrione and other p‐hydroxyphenylpyruvate dioxygenase (HPPD)‐inhibiting herbicides and gl...
Article
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Abstract Background Ladybird beetles (Coleoptera: Coccinellidae) are abundant predatory species in many agroecosystems, are valued for their biological pest control functions, and have been recommended as test species for studies supporting the assessment of non-target effects of insect-resistant Bt crops. Although insecticidal Bt proteins are know...
Article
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Abstract Soybean MON 87751 × MON 87701 × MON 87708 × MON 89788 (four‐event stack soybean) was produced by conventional crossing to combine four single events: MON 87751, MON 87701, MON 87708 and MON 89788. The GMO Panel previously assessed the four single events and did not identify safety concerns. No new data on the single events have been identi...
Article
Full-text available
Soybean MON 877089MON 897889A5547-127 (three-event stack soybean) was produced byconventional crossing to combine three single events: MON 87708, MON 89788 and A5547-127. TheGMO Panel previously assessed the three single events and did not identify safety concerns. No newdata on the single events, leading to modification of the original conclusions...
Article
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Abstract Pre‐market/prospective environmental risk assessments (ERAs) contribute to risk analyses performed to facilitate decisions about the market introduction of regulated stressors. Robust ERAs begin with an explicit problem formulation, which involves among other steps: (1) formally devising plausible pathways to harm that describe how the dep...
Article
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Ecosystem services (ES) are the benefits that people obtain from ecosystems. Investigating the environment through an ES framework has gained wide acceptance in the international scientific community and is applied by policymakers to protect biodiversity and safeguard the sustainability of ecosystems. This approach can enhance the ecological and so...
Article
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Abstract From 18–21 September 2018, EFSA hosted its third Scientific Conference on Science, Food and Society in Parma, Italy. This paper summarises the overall recommendations on future actions and research priorities of the conference and complements the earlier multi‐authored papers in this issue. The conference started and closed with the plenar...
Article
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Abstract The interplay between science, risk assessment and risk management has always been complex, and even more so in a world increasingly characterised by rapid technical innovation, new modes of communication, suspicion about authorities and experts, and demands for people to have a say in decisions that are made on their behalf. In this chall...
Article
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Abstract Following a request from the European Commission, EFSA assessed the 2017 post‐market environmental monitoring (PMEM) report on the cultivation of Cry1Ab‐expressing maize event MON 810. Like previous years, partial compliance with refuge requirements is reported for Spain. European and Mediterranean corn borer populations collected from Nor...
Article
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The scope of application EFSA‐GMO‐DE‐2016‐133 is for food and feed uses, import and processing of genetically modified (GM) maize MZHG0JG in the European Union. Maize MZHG0JG was developed to confer tolerance to the herbicidal active substances glyphosate and glufosinate‐ammonium. The molecular characterisation data and bioinformatic analyses do no...
Article
The reporting of teosinte and maize × teosinte hybrid plants in maize fields in Spain and France has fuelled the continuing debate on the environmental risks and benefits of genetically modified (GM) crops in Europe. Concern has been expressed that GM maize may hybridise with teosinte or maize × teosinte hybrids, leading to the development of invas...
Article
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Abstract Following a request from the European Commission, EFSA assessed the annual post‐market environmental monitoring (PMEM) report for the 2016 growing season of the Cry1Ab‐expressing maize event MON 810 provided by Monsanto Europe S.A. Partial compliance with refuge requirements was reported in Spain, as observed in previous years. EFSA reiter...
Article
Full-text available
Maize 4114 was developed through Agrobacterium tumefaciens-mediated transformation to provide protection against certain lepidopteran and coleopteran pests by expression of the Cry1F, Cry34Ab1 and Cry35Ab1 proteins derived from Bacillus thuringiensis, and tolerance to the herbicidal active ingredient glufosinate-ammonium by expression of the PAT pr...
Article
Full-text available
Maize MON 87403 was developed to increase ear biomass at early reproductive phase through the expression of a modified AtHB17 gene from Arabidopsis thaliana, encoding a plant transcription factor of the HD-Zip II family. The molecular characterisation data and bioinformatic analyses did not identify issues requiring assessment for food and feed saf...
Article
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This document provides guidance for the risk assessment under Regulation (EC) No1829/2003 of the unintended, adventitious or technically unavoidable presence in food and feed of low level of genetically modified plant material intended for markets other than in the European Union. In this context, the presence at low level is defined to be maximum...
Article
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Following the submission of application EFSA-GMO-RX-004 under Regulation (EC) No 1829/2003 from Bayer CropScience, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) was asked to deliver a scientific risk assessment on the data submitted in thecontext of the renewal of authorisation application of the gene...
Article
Full-text available
Following a request from the European Commission, the Panel on Genetically Modified Organisms of the European Food Safety Authority (GMO Panel) assessed the annual post-market environmental monitoring (PMEM) report for the 2015 growing season of the Cry1Ab-expressing maize event MON 810 provided by Monsanto Europe S.A. The GMO Panel concludes that...
Technical Report
Guidance of the Panel on Genetically Modified Organisms (GMOs) of the European Food Safety Authority (EFSA) assists applicants in the preparation and presentation of their market registration applications by describing elements and information/data requirements for the risk assessment and monitoring of GMOs. This explanatory note to the guidance: (...
Article
Conventionally bred (CHT) and genetically modified herbicide-tolerant (GMHT) crops have changed weed management practices and made an important contribution to the global production of some commodity crops. However, a concern is that farm management practices associated with the cultivation of herbicide-tolerant (HT) crops further deplete farmland...
Technical Report
Full-text available
Following a request of the European Commission, the European Food Safety Authority (EFSA) assessed the available scientific information on teosinte for its relevance for the environmental risk assessment (ERA) of genetically modified (GM) maize MON810, Bt11, 1507 and GA21 for cultivation. The presence of teosinte in the European Union (EU) has been...
Article
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The potential risks that genetically modified plants may pose to non-target organisms and the ecosystem services they contribute to are assessed as part of pre-market risk assessments. This paper reviews the early tier studies testing the hypothesis whether exposure to plant-produced Cry34/35Ab1 proteins as a result of cultivation of maize 59122 is...
Technical Report
Full-text available
Following a request from the European Commission, the European Food Safety Authority (EFSA) assessed the relevance of the Hofmann et al. (2016) publication for the environmental risk assessment and risk management of the Bt-maize events MON810, Bt11 and 1507 for cultivation. Hofmann et al. (2016) reported data on pollen deposition on maize and weed...
Technical Report
Full-text available
Following a request from the European Commission, the European Food Safety Authority (EFSA) assessed the scientific publication by Bøhn et al. (2016), including its relevance for the environmental risk assessment of Bt-maize events MON810 and Bt11 for cultivation. In their publication, Bøhn et al. (2016) reported that the purified Cry1Ab protein is...
Article
Full-text available
The pre-market environmental risk assessment (ERA) of regulated products such as genetically modified organisms, plant protection products and feed additives is an important process to safeguard the desired level of protection of the environment and biodiversity. ERA evaluates the potential adverse effects on the environment of certain actions, and...
Conference Paper
Full-text available
The pre‐market environmental risk assessment (ERA ) of regulated products such as genetically modified organisms, plant protection products and feed additives is an important process to safeguard the desired level of protection of the environment and biodiversity. ERA evaluates the potential adverse effects on the environment of certain actions, an...
Article
Full-text available
Maintaining a healthy environment and conserving biodiversity are major goals of environmental protection. A challenge is that protection goals outlined in legislation are often too general and broad to be directly applicable for environmental risk assessment (ERA) performed by EFSA. Therefore, they need to be translated into specific protection go...
Article
Genetically modified (GM) plants and derived food and feed products are subject to risk assessment and regulatory approval before these can be marketed in the European Union (EU). This pre‐market risk assessment follows international standards to evaluate whether characteristics of the GM plant associated with the genetic modification are capable o...
Conference Paper
Full-text available
Future applications for the marketing of genetically modified organisms (GMOs) in the EU may include food/feed products derived from genetically modified (GM) animals, and the release of GM animals, including insects, into the environment. Efforts towards the development of GM insects to control insect vectors of human diseases and manage agricultu...
Technical Report
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Following a request from the European Commission, the European Food Safety Authority (EFSA) evaluated the documentation provided by Austria to support the prolongation of the safeguard clause measure prohibiting the placing on the market of genetically modified oilseed rape Ms8, Rf3 and Ms8×Rf3 for food and feed uses in Austria. EFSA assessed wheth...
Technical Report
Full-text available
Following a request from the European Commission, the European Food Safety Authority (EFSA) evaluated the documentation provided by Austria to support the prolongation of the safeguard clause measure prohibiting the placing on the market of genetically modified oilseed rape GT73 for food and feed uses in Austria. EFSA assessed whether the submitted...
Technical Report
Full-text available
The EFSA performs environmental risk assessment (ERA) for single potential stressors such as plant protection products, genetically modified organisms and feed additives, and for invasive alien species that are harmful to plant health. This ERA focusses primarily on the use or spread of such potential stressors in an agricultural context, but also...
Article
Full-text available
The EFSA performs environmental risk assessment (ERA) for single potential stressors such as plant protection products, genetically modified organisms and feed additives, and for invasive alien species that are harmful to plant health. This ERA focusses primarily on the use or spread of such potential stressors in an agricultural context, but also...
Technical Report
Full-text available
Following a request from the European Commission, the European Food Safety Authority (EFSA) assessed the findings reported by Trtikova et al. (2015). The relevance of these findings for the risk assessment of maize MON 810 and other Cry1Ab-expressing Bt-maize events for which the EFSA GMO Panel has already issued a scientific opinion was also asses...