Yan Zhang

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Verified

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• Professor
• Professor (Full) at Central South University

Line defects, dislocations, in ferroelectric materials can facilitate the nucleation of new domains and pin the motion of domain walls, leading to significant electromechanical responses. However, the mechanisms that how dislocations influence surrounding atoms and domains remains unclear. In this study, the influence of mechanically introduced {10...

Focused vector vortex beams (VVBs) offer significant potential for applications in nonlinear effects, quantum optics, and communications due to their symmetric intensity patterns, phase singularities, and structured polarization profiles. Nevertheless, the emerging frontier of dynamically tunable VVBs in the THz regime faces critical limitations in...

Terahertz vortex beams, carrying orbital angular momentum (OAM), are quite desirable for enhancing data transmission capability in telecommunication. However, it faces fundamental and technical challenges in a single metasurface to simultaneously generate orthogonal basis vortices with linear polarization ( x - and y -polarity) and circular polariz...

Studying organelles’ interactome at system level requires simultaneous observation of subcellular compartments and tracking their dynamics. Conventional multicolor approaches rely on specific fluorescence labeling, where the number of resolvable colors is far less than the types of organelles. Here, we use a lipid-specific dye to stain all the memb...

Terahertz (THz) microscopy has become an important far-infrared inspection method because it possesses a high spatial resolution and retains THz spectral information. For further exploiting applications of THz microscopy, we propose an air-plasma dynamic aperture-based THz near-field technique to achieve sub-wavelength THz imaging without approachi...

With the rapid development of the Internet of Things, there exists an urgent necessity for high performance piezoelectric energy harvesters to facilitate the construction of more efficient wireless sensor systems....

Neutrophil extracellular traps (NETs) play a critical role in acute myocardial infarction (AMI) and the externalization of S100 family members. Here, we show the effects of S100A12 on NETs formation and myocardial injury following AMI. S100A12 expression increases rapidly in neutrophils and peaks on day 1 after AMI, promoting NETs production and ex...

Substantial progress is made in the past two decades in improving the room‐temperature piezoelectric coefficient of lead‐free (K, Na)NbO3 (KNN) based ferroelectric ceramics, allowing them to rival commercial lead zirconate titanate. However, within the theoretical framework, the role of key element antimony (Sb) for the enhanced piezoelectricity ha...

Bismuth‐layered ferroelectric nanomaterials exhibit great potential for piezo‐photocatalysis. However, a major challenge lies in the difficulty of recovering the catalytic powders, raising concerns regarding secondary pollution of water. In this work, a novel hierarchical porous ferroelectric ceramic containing {110} surface‐exposed Bi3.15Nd0.85Ti3...

Next-generation advanced high/pulsed power capacitors rely heavily on dielectric ceramics with high energy storage performance. Although high entropy relaxor ferroelectric exhibited enormous potential in functional materials, the chemical short-range order, which is a common phenomenon in high entropy alloys to modulate performances, have been paid...

The Na/Sm co-doped CaBi 2 Nb 2 O 9 textured ceramics with a high texture degree of 95–98% were successfully prepared by improved grain growth method, achieving the highest piezoelectric coefficient ( d 33 > 30 pC N ⁻¹ ) in the CaBi 2 Nb 2 O 9 systems.

It has been widely accepted that resistant starch (RS) provides numerous health benefits for human. In this research, we aimed at evaluating the performance of novel starch-lipid complexes, RS5, in comparison with RS2 on physical features, glucolipids metabolism, inflammation, and gut microbiota profiles of type 2 diabetes mellitus (T2DM) rats. The...

The rapid development of society has exacerbated energy scarcity, making water splitting a promising solution for humanity to produce green hydrogen. Therefore, enhancing the relatively low catalytic performance of piezoelectric bulk catalysts is crucial to unlocking their potential for broader practical applications and potentially alleviating con...

Advances in wireless communication systems require multifunction‐integrated optical devices to increase information capacities. However, the wavefront‐shaping metasurfaces thus far face challenges in manipulating orthogonal polarization independently and achieving versatile wavefront shaping simultaneously. Here, the scheme of chip‐integrated multi...

β-Hydroxybutyrate (β-OHB), the primary ketone body, is a bioactive metabolite that acts as both an energy substrate and a signaling molecule. Recent studies found that β-OHB inhibits the production of pro-inflammatory cytokines in macrophages, but its underlying molecular mechanisms have not yet been fully elucidated. Lysine β-hydroxybutyrylation (...

Currently, reported physical or chemical methods to produce flexible perovskite thin films rely on the use of expensive single crystal substrates or large‐scale precision equipment. Here, a high‐performance ultrasensitive piezoelectric sensor via a cost‐effective strategy is developed to enable the release of lead zirconate titanate (PZT) thin film...

Bismuth ferrite (BiFeO3)‐based high‐temperature piezoelectric ceramics have high Curie temperatures and excellent thermal stability; however, their applications are limited by inadequate piezoelectric performance due to large coercive fields and high leakage conduction. This study investigates the impact of MnO2 doping on the phase transition, defe...

The trade-off between electrostrain and strain hysteresis for piezo/ferroelectric materials largely restrains the development of high precision actuators and remains unresolved over the past few decades. Here, a simple composition of (Bi0.5Na0.5)1-x/100Srx/100TiO3 in the ergodic relaxor state is collaboratively designed through the segregated domai...

Cardiac lymphatics play an important role in myocardial edema and inflammation. This study integrated single-cell sequencing data and spatial transcriptome data from mouse heart tissue at different time points post-myocardial infarction (MI), and identified four transcriptionally distinct subtypes of lymphatic endothelial cells(LECs) and localized...

Effective synthesis and application of single-atom catalysts on supports lacking enough defects remain a significant challenge in environmental catalysis. Herein, we present a universal defect-enrichment strategy to increase the surface defects of CeO2-based supports through H2 reduction pretreatment. The Pt catalysts supported by defective CeO2-ba...

Ubiquitous noise pollution has been associated with significant negative impacts on human health. However, current porous sound‐absorbing materials encounter considerable obstacles such as thick density, narrow absorbing band, and limited function. Here, a facile‐producing method for lightweight and efficiently sound‐absorbing aerogels made from ba...

As a novel terahertz (THz) source, a spintronic THz emitter (STE) has become a research hot topic recently due to its ultra-broadband emission, powerful scalability, simple fabrication, and ultrawide pump-wavelength range. To optimize the performance of a STE, its spintronic heterostructure has been extensively investigated and its accessories have...

Therapeutic resistance represents a bottleneck to treatment in advanced gastric cancer (GC). Ferroptosis is an iron-dependent form of non-apoptotic cell death and is associated with anti-cancer therapeutic efficacy. Further investigations are required to clarify the underlying mechanisms. Ferroptosis-resistant GC cell lines are constructed. Dysregu...

Metasurface has the ability to flexibly modulate the wavefront and detect the polarization states, thus receiving widespread research attention. The combination of polarization multiplexing techniques and focused beams with polarization information provides a new approach to compact polarization detection behavior. Here, an all-dielectric metasurfa...

Protein S-acylation catalyzed by protein S-acyl transferases (PATs) is a reversible lipid modification regulating protein targeting, stability, and interaction profiles. PATs are encoded by large gene families in plants, and many proteins including receptor-like cytoplasmic kinases (RLCKs) and receptor-like kinases (RLKs) are subject to S-acylation...

Intervertebral disc degeneration (IDD) is widely recognized as the primary culprit of chronic low back pain. Restoring deteriorated intervertebral disc (IVD) and alleviating IDD‐induced low back pain are remaining enormous challenges. There is a genetic susceptibility to IDD, and gene therapy has some therapeutic potential. However, traditional gen...

Previous studies have shown that advanced glycation end products (AGEs) are implicated in the occurrence and progression of numerous diseases, with dietary AGEs being particularly associated with intestinal disorders. In this study, methylglyoxal-beta-lactoglobulin AGEs (MGO-β-LG AGEs) were utilized as the exclusive nitrogen source to investigate t...

Stretchable self‐powered sensors are of significant interest in next‐generation wearable electronics. However, current strategies for creating stretchable piezoelectric sensors based on piezoelectric polymers or 0–3 piezoelectric composites face several challenges such as low piezoelectric activity, low sensitivity, and poor durability. In this pap...

Powder‐based piezo‐catalysis, as an effective approach to degrade wastewater and produce hydrogen from water splitting, has been widely used in the field of energy conservation and pollution reduction. However, these hard‐to‐recycle powders pose a challenge of secondary pollution in the environment. As a result, this paper provides an alternative s...

658 Background: Metastatic pancreatic cancer is a leading cause of cancer death worldwide with limited treatment options. Durvalumab, the anti- PD-L1 inhibitor has revealed remarkable efficacy in solid malignancies including hepatobiliary cancers. We conducted a study to evaluate the efficacy and safety of a combination therapy of Durvalumab, Album...

504 Background: BTCs are a heterogeneous group of malignancies with a poor prognosis. Despite the improved outcome achieved by the addition of the anti-PD-L1 antibody durvalumab to standard chemotherapy, the benefits were modest and cannot satisfy the clinical demands adequately. This study aimed to evaluate the efficacy and safety of the combinati...

A recently proposed method is upgraded to convert two amplitude phase modulation systems (APMSs) to pure phase elements (PPEs), for generating the stable propagation Bessel beam and the axial multifoci beam, respectively. Phase functions of the PPEs are presented analytically. Numerical simulations by the complete Rayleigh–Sommerfeld method demonst...

A series of barium zirconate modified potassium sodium niobate-based lead-free piezoelectric ceramics [(0.97-x)(K0.45Na0.55)(Nb0.97Sb0.03)O3-0.03Bi0.5K0.075Na0.425ZrO3-xBaZrO3, KNNS–BKNZ–xBZ, x = 0 ~ 0.02] were prepared by the traditional solid-state method. The effect of BZ on the phase structure and electrical properties was systematically studie...

Polarization is crucial in various fields such as imaging, sensing, and substance detection. A compact, fast, and accurate polarization detection device is vital for these applications. Herein, we demonstrate a multifocus metalens for terahertz polarization detection that requires only a single measurement to obtain complete polarization parameters...

Experiments and calculations reveal the key role of Nd in piezoelectric property enhancement and bandgap reduction, which unveil piezo-photocatalysis mechanisms.

Powder-based piezoelectric catalysts have been widely examined due to their high catalytic activity for applications such as water treatment and dye degradation. However, challenges remain which are associated with secondary...

An optically rewritable and electrically erasable terahertz (THz) wavefront modulator based on indium oxide (In2O3) and DMSO-doped PEDOT:PSS is proposed. The modulator has a three-layer structure of In2O3/PEDOT:PSS/quartz, which can weaken the THz transmission under the action of light excitation. Optically written THz Fresnel plates, which can foc...

The manipulation and detection of polarization states play a crucial role in the application of 6G terahertz communication. Nonetheless, the development of compact and versatile polarization detection devices capable of detecting arbitrary polarizations continues to be a challenging endeavor. Here, we demonstrate a terahertz polarization detection...

Importance Sex disparities in the management and outcomes of acute coronary syndrome (ACS) have received increasing attention. Objective To evaluate the association of a quality improvement program with sex disparities among patients with ACS. Design, Setting, and Participants The National Chest Pain Centers Program (NCPCP) is an ongoing nationwi...

We propose what we believe to be a new kind of diffractive phase element, i.e., vortex phase plate (VPP) with phase singularities along the azimuth direction. Phase function of the proposed VPP is given analytically. Axial intensity oscillations of propagating Bessel beams are ideally suppressed by using the proposed VPP. Compared with the traditio...

Metasurfaces have demonstrated unprecedented capabilities in modulating the polarization and phase of electromagnetic waves and formed an emerging field of research, driving the exploitation of versatile compact devices. In this work, one transmission‐mode, multichannel all‐silicon metasurface platform that can implement functionalities separately...

Introduction: The main aim of this study was to investigate the impact of isolated coronary microvascular disease (CMD) as diagnosed via various modalities on prognosis. Method: A systematic literature review of PubMed, Embase, and Cochrane library databases was conducted to identify relevant studies published up to March 2023. Included studies...

Background Hypertension (HT) and cardiac damage are the most common complications in pheochromocytoma and paraganglioma (PPGL). Although cardiovascular manifestations have been concerned in previous studies, the profile of HT and cardiac structure and function alteration in a large cohort of PPGL were rarely reported. In this study, we focused on H...

Reuterin can be produced from glycerol dehydration catalyzed by glycerol dehydratase (GDHt) in Lactobacillus reuteri and has broad application prospects in industry, agriculture, food, and other fields as it is active against prokaryotic and eukaryotic organisms and is resistant to proteases and lipases. However, high concentrations of glycerin inh...

CoO has attracted increasing attention as an electrochemical energy storage owing to its excellent redox activity and high theoretical specific capacitance. However, its low inherent electrical conductivity results in sluggish reaction kinetics, and the poor rate capability of CoO limits its widespread applications. Herein, a multiple-defect strate...

The gluten protein content in whole-wheat flour is low, which affects the elasticity and viscosity of dough. Enzymatic modification of the protein may result in a network that mimics gluten, which plays an important role in the processing of whole-wheat foods. In this study, the effects of Halomonas alkaliantartica laccase (LacHa) on the quality pa...

Currently, kinase inhibitors have been applied in the diagnosis or treatment of cancer with their unique advantages. It is of great significance to develop some comprehensive theranostic reagents based on kinase inhibitors to improve the performance of reagents for biomedical applications. Besides, tracking changes in the intracellular environment...

Lipid oxidation can produce lipid oxidation products (LOPs), which further react with proteins and affect their structure and digestibility, although the underlying mechanism remains unclear. Herein, we investigated the conformation and digestibility of proteins induced by LOPs after thermal treatment. Digestibility of myoglobin (Mb) affected by tr...

Perioperative neurocognitive disorder (PND) is a common complication of surgery and anesthesia, especially among older patients. Microglial activation plays a crucial role in the occurrence and development of PND and transforming growth factor beta 1 (TGF-β1) can regulate microglial homeostasis. In the present study, abdominal surgery was performed...

In this study, direct ink writing (DIW) was applied to preparing polyvinylidene fluoride (PVDF) film. The rheological properties of inks were studied, and the influence of process parameters on material properties was systematically investigated by SEM, FTIR, DSC, dielectric, ferroelectric and piezoelectric properties testing. The results show that...

The µW‐level power density of flexible piezoelectric energy harvesters (FPEHs) restricts their potential in applications related to high‐power multifunctional wearable devices. To overcome this challenge, a hierarchical design strategy is proposed by forming porous piezoceramics with an optimum microstructure into an ordered macroscopic array struc...

The binary amplitude filter (BAF) is employed to generate stable propagation Bessel beams and axial multifoci beams, rather than the traditional continuous amplitude filter (CAF). We introduce a parameter along the azimuth direction, i.e., angular order of the BAF, to weaken transverse intensity asymmetry. Numerical simulations reveal that the BAF...

Introduction Laccase is a copper-containing polyphenolic oxidase widely found in bacteria, archaea, fungi, animals, and plants. As a green biocatalyst with considerable potential for numerous environmental and industrial applications, the enzyme production efficiency of laccase in nature is low, and the cost is high. Purpose To examine the charact...