Xuchun Qiu

• PhD
• Professor at Jiangsu University

This study investigated temporal variations in the potential maximum quantum yield of photosystem II (F(v)/F(m) ratio) and growth-phase dependent cellular protein expressions of Chattonella antiqua under laboratory conditions. Despite the culture conditions, significant positive correlations between the F(v)/F(m) ratio and daily growth rate were ob...

The behavioral and biochemical responses of Japanese medaka (Oryzias latipes) to acute and subacute (sublethal) levels of chlorpyrifos were studied. In the acute exposure test, medaka were exposed to 0.018, 0.055, 0.166, or 0.500mgL(-1) chlorpyrifos for 4d. As a result, fish showed hypoactivity compared to the control (at 0.018, 0.055, and 0.166mgL...

We investigated the growth interactions between the raphidophyte Chattonella antiqua and the dinoflagellate Akashiwo sanguinea by using bi-algal cultures under axenic conditions. When initial cell densities of C. antiqua and A. sanguinea both were 1 × 102 cells ml−1, C. antiqua grew faster and its growth inhibitory effect on A. sanguinea was strong...

The coexistence of microplastics and hydrophobic organic chemicals is ubiquitous in the environment. Microplastics may act as vectors for the transmission of organic pollutants to organisms. In the present study, we co-exposed 33 adult medaka sh to a mixture of chlorobenzenes (CBs; trichlorobenzene, tetrachlorobenzene, penta-chlorobenzene, and hexa...

Diurnal rhythms in physiological functions contribute to homeostasis in many organisms. Although relationships between molecular biology and diurnal rhythms have been well studied in model organisms like higher plants, those in harmful algal bloom species are poorly understood. Here we measured several physiological parameters and the expression pa...

Climate change and CO2 emissions are critical challenges for the environment and humanity. There is extensive literature on greenhouse gas (GHG) emissions, in particular CO2 emissions. However, comprehensive analyses focusing on electric vehicles (EVs) and their impact are lacking. This study fills this gap by conducting a bibliometric analysis of...

Microplastics and antibiotics are emerging as ubiquitous contaminants in farmland soil, harming crop quality and yield, and thus threatening global food security and human health. However, few studies have examined the individual and joint effects of degradable and/or non-degradable microplastics and antibiotics on crop plants. This study examined...

Microplastics have been detected in a variety of aquatic ecosystems, and the combined effect of microplastics and chemical pollutants has become a matter of increasing concern. We conducted a 12-d co-exposure test of anthracene and spherical or fragmented polyethylene microplastics (size 200 µm) on Java medaka (Oryzias javanicus). The accumulation...

Solar‐driven reduction of nitrogen to ammonia is a promising green approach and is considered as a sustainable alternative to the Haber–Bosch process. Carbon nitride (g‐C3N4) is an ideal non‐metallic semiconductor photocatalyst for photocatalytic N2 reduction reaction (p‐NRR). In this work, we designed a simple supramolecular self‐assembly method t...

Pollution by microplastics in aquatic ecosystems is a worldwide problem, and the role of microplastics as vectors of pollutants has been a concern. Although small microplastics are thought to have a greater effect than large microplastics as vectors of pollutants, the impact of the size of microplastics on their ability to serve as vectors of pollu...

Zeolitic imidazolate framework-8 nanoparticles (ZIF-8 NPs) are typical metal–organic framework (MOF) materials and have been intensively studied for their potential application in drug delivery and environmental remediation. However, knowledge of their potential risks to health and the environment is still limited. Therefore, this study exposed fem...

It was urgent to improve the intuitive, portable, sensitive and multi-modal detection method for small molecules. In this study, a tri-modal readout of plasmonic colorimetric immunosensor (PCIS) for small molecule (zearalenone, ZEN, as an example) had been established based on the Poly-HRP amplification and gold nanostars (AuNS) etching. The immobi...

The potential toxicity of microplastics (MPs) and hydrophilic pharmaceuticals to aquatic organisms has recently raised great public concern, yet their combined effects on aquatic organisms remain largely unknown. Herein, the combined effects of MPs and the commonly prescribed amitriptyline hydrochloride (AMI) on the intestinal tissue and gut microb...

Emissions play a crucial role in sustainable development since they are the primary cause of climate change, which has a significant impact on the environment. Emissions are connected with many sustainable development goals (SDGs) set by the United Nations. Reducing emissions may contribute to climate change mitigation, clean energy delivery, and t...

Endocrine-disrupting chemicals (EDCs) are now ubiquitously distributed in the environment. Tetrabromobisphenol A bis(2-hydroxyethyl) ether (TBBPA-DHEE) pollution in environment media poses a significant threat to humans and aquatic organisms as a result of its potential neurotoxicity and endocrine-disrupting effect. The endocrine-disrupting effects...

This study investigated the changes in the sinking rates and physiochemical characteristics of the planktonic marine diatom, Thalassiosira pseudonana, caused by 72 h exposure to antifouling agent tributyltin (TBT) at 1.0 µg L⁻¹ (72-h 10% effective concentration for growth rate, EC10), and 1.7 µg L⁻¹ (EC50). After 72 h of exposure, the sinking rates...

It is desired and urgently needed to improve the sensitivity of immunochromatography assay (ICA) for hazardous chemicals. In this work, an enhanced ICA strip was established and evaluated for simultaneous, semi-quantitative and quantitative detection of ochratoxin A (OTA) and aflatoxin B1 (AFB1). The signal strategy based on gold growth on the surf...

The combined effect of microplastics and pharmaceuticals on aquatic organisms is an issue of concern. In this laboratory study, we evaluated the combined effect of polystyrene microplastics (2-μm diameter) and diazepam on the social behavior of medaka (Oryzias latipes) by using the shoaling behavior test with five treatment groups: solvent control,...

Amitriptyline (AMI), the most commonly prescribed tricyclic antidepressant, is widely detected in water environments. Exposure to AMI may lead to diverse adverse effects on aquatic organisms, but little is known about the effect of short-term exposure to AMI on the gut microbiota of aquatic organisms and their recovery characteristics. In the prese...

Cetylpyridinium chloride (CPC) is a cationic surfactant that has been widely used as an antibacterial ingredient in pharmaceutical and personal care products. Due to its high residue in surface waters, there is increasing concern over the potential risk of CPC to aquatic ecosystems. However, knowledge of its impacts on fish is still limited. Theref...

The overuse of chromium (Cr) has significantly negatively impacted human life and environmental sustainability. Recently, the employment of nano zero-valent iron (nZVI) for Cr(VI) removal is becoming an emerging approach. In this study, carbonized melamine foam-supported nZVI composites, prepared by a simple impregnation–carbonization–reduction met...

An energy-efficient and environmentally friendly nitrogen fixation process is urgently needed to solve problems of high energy consumption and high emissions in the traditional ammonia industry. In this work, a Z-scheme porous g-C3N4/ZnFe2O4 photocatalyst was synthesized, characterized and employed for N2 photofixation. Temperature programmed desor...

An ultrasensitive fluorometric oligonucleotide immunoassay (UFOIA) based on a fluorometric oligonucleotide and magnetic separation was proposed for the simultaneous detection of two mycotoxins. Two kinds of magnetic nanoparticle (MNP) probes and their corresponding fluorometric oligonucleotide probes were prepared. After the immune reaction, Cy5-li...

The combined application of nanoparticles and surfactants has attracted tremendous attention in basic research and industry. However, knowledge of their combined toxicity remains scarce. In this study, we exposed zebrafish embryos to cetylpyridinium chloride (CPC, a cationic surfactant, at 0 and 20 μg/L), zeolitic imidazolate framework nanoparticle...

Cetylpyridinium chloride (CPC) is a widely used surfactant that has been detected in various water ecosystems. However, knowledge on the toxicity of CPC to fish remains scarce. Here, we examined the survival, development, behavior, and oxidative stress in the early life stages of zebrafish exposed to CPC (0, 4, 40, 400, and 1200 μg/L) until 120 h p...

Discontinuation of amitriptyline (AMI) has been demonstrated to induce long-term withdrawal syndromes in mammals. However, no studies have focused on the persistent impacts of short-term AMI exposure on teleosts. Here, following exposure to AMI (2.5 and 40 μg/L) for 7 days (E7), zebrafish were transferred into AMI-free water to recover for 21 days...

The widely used compound tributyltin (TBT), which can be continuously detected in aquatic species and seafood, may induce diverse adverse effects on aquatic organisms. However, little is known regarding the mechanistic links between behavioral abnormality and oxidative stress in different fish tissues in response to oral TBT exposure. Herein, juven...

Tetrabromobisphenol S (TBBPS), an emerging brominated flame retardant (BFR) has been widely detected in the environment, and may potentially pose environmental risks. However, data on the occurrence and toxic effects of TBBPS are limited. Circadian rhythms govern multiple behavioral and physiological processes, and their disruption is closely assoc...

Z-scheme nitrogen-deficient graphitic carbon nitride/ferric oxide (GCNx/FO) photocatalysts were obtained by a one-step calcination method. The number of nitrogen defects was tuned by the application of KOH, while the ferric oxide phase and magnetism was controlled by the usage of ferrous oxalate. Interconversion between the hematite (α) and maghemi...

The widely used antifoulant tributyltin chloride (TBT) is highly toxic to aquatic organisms. In the present study, four-week-old Japanese medaka (Oryzias latipes) juveniles were orally exposed to TBT at 1 and 10 ng/g bw/d for 1, 2, and 4 weeks, respectively. Half of the tested medaka juveniles showed bone morphology alterations in both 1 and 10 ng/...

Dibutyl phthalate (DBP) and diisobutyl phthalate (DiBP) have been reported to exhibit reproductive toxicity in vertebrates. However, the combined effect of DBP and DiBP on offspring of exposed parents remains unclear, especially for aquatic organisms such as fish. The aims of this study were to assess the effects of parental co-exposure to DBP and...

We investigated the pollution levels of 6 heavy metals and 29 dioxins (polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (DL-PCBs)) in intertidal and supratidal zones by using wharf roaches (Ligia spp.) collected from 12 sampling sites on the coast of Northeast Japan from Nov...

BACKGROUND The ultrasensitive monitoring strategy of zearalenone (ZEN) is essential and desirable for food safety and human health. In the present study, a coupling of gold nanoparticles‐DNA barcode and direct competitive immunoassay‐based real‐time polymerase chain reaction signal amplification (RT‐IPCR) for ZEN close to the sensitivity of PCR‐lik...

Microplastic (MP) pollution and the related impacts on aquatic species have drawn worldwide attention. However, knowledge of the kinetic profiles of MPs in fish remains fragmentary. In this study, we conducted exposure and depuration tests of the following fluorescent-labeled MPs: polyethylene (PE; sphere with 200 or 20 µm diameter) and polystyrene...

Peroxiredoxin (Prx) is a relatively recently discovered antioxidant enzyme family that scavenges peroxides and is known to be present in organisms from biological taxa ranging from bacteria to multicellular eukaryotes, including photosynthetic organisms. Although there have been many studies of the Prx family in higher plants, green algae, and cyan...

Di-(2-ethylhexyl) phthalate (DEHP), one of the most common plasticizers, is closely associated with a high prevalence of pubertal type 2 diabetes mellitus (T2DM). Numerous studies have indicated that DEHP-induced metabolic toxicity exhibits sex differences. In this study, the sex differences in the effect of DEHP on pubertal T2DM (P-T2DM) mice, the...

Residues of the psychoactive drug diazepam (DZP) may pose potential risks to fish in aquatic environments, especially by disrupting their behavioral traits. In this study, female and male zebrafish were subjected to chronic exposure (21 days) to sublethal doses (120 and 12 µg/L) of DZP, aimed to compare the characteristics of their behavioral respo...

Selection of suitable reference genes is important for relative quantification in quantitative PCR (qPCR). We investigated the expression stability of candidate reference genes for qPCR in the raphidophyte Chattonella marina at different irradiance, temperature, and oxidative stress conditions, and in different growth phases. Nine candidate referen...

Tributyltin-binding protein type 2 (TBT-bp2), a homolog of α1-acid glycoprotein, may contribute to both accumulation and detoxification of TBT in fish. In this study, we conducted acute TBT exposure tests using both wide-type (WT) and TBT-bp2−/− (KO) strains of medaka and compared their responses in survival time and accumulation of TBT. Deficiency...

This study was performed to elucidate the uptake and bioaccumulation of polystyrene microplastics (PS-MPs) in Japanese medaka (freshwater fish) and Java medaka (marine fish), and to assess its impacts on the survival, reproduction, and gene expression of Japanese medaka. Both species were exposed to 2-μm fluorescent PS-MPs (10⁷ beads/L) for 3 weeks...

An energy-efficient and environmentally friendly nitrogen fixation process is urgently needed for cleaner ammonia production. In this study, a Z-scheme single-layer g-C3N4/ZnFe2O4 photocatalyst was designed, characterized and used for the cleaner production of ammonia by N2 photofixation. From the N2 photofixation evaluation experiments, the ammoni...

Many biological features of Chattonella species display diurnal oscillations, but little is known about the corresponding cellular responses at the proteome level. In the present study, we hypothesized that the abundance of certain proteins would periodically fluctuate to suit the diurnal changes of biological processes in Chattonella cells. To tes...

Environmental pollution by the psychoactive drug diazepam (DZP) has been suggested to disrupt various behavioral traits of fishes. Exposure to DZP in natural waters may be of episodic duration, but there are few reports on the persistence of abnormal behaviors of fishes caused by such acute exposure. In the current study, we exposed juvenile zebraf...

In the present study, the neurotoxicity and mechanisms of di-(2-ethylhexyl) phthalate (DEHP) exposure on pubertal normal (P-normal) and pubertal type 2 diabetes mellitus (P-T2DM) mice were investigated by typical neurobehavioral methods and transcriptome analysis. Pubertal male ICR mice were orally exposed to DEHP (0.18, 1.8, 18 and 180 mg/kg/d) fo...

Chattonella spp. are known to produce large amounts of reactive oxygen species (ROS); however, little is known about the mechanisms involved in mitigating the intracellular accumulation of ROS. In this study, a time-series of biological responses in C. marina var. antiqua under different oxidative stress conditions, induced by adding H2O2 at the in...

Being the precursor of serotonin and melatonin, dietary supplementation with tryptophan (TRP) may modulates behavior, stress responses, and antioxidant capacity in fish. In this study, effects of Chattonella exposure on the swimming behavior and brain monoamine metabolism of yellowtail fed a commercial diet (control diet) or that enriched by 1.5% L...

The prevalence of adolescent type 2 diabetes mellitus (A-T2DM) is increasing year by year. Di-(2-ethylhexyl)phthalate (DEHP), a widely used plasticizer, could exacerbate type 2 diabetes mellitus (T2DM). The study aimed to investigate the metabolic toxicity, susceptibility and mechanism of DEHP exposure to A-T2DM. DEHP was administered orally (0, 0....

Phthalate esters (PAEs), which are notable plasticizers, can be prolific contaminants in aquatic environments, and have been shown to induce reproductive toxicity. However, the studies concerning their toxicity towards aquatic species are based on individual chemicals, and the combined toxicity of PAEs to aquatic organisms remains unclear. The aim...

Antioxidant enzymes are essential proteins that maintain cell proliferation potential by protecting against oxidative stress. They are present in many organisms including harmful algal bloom (HAB) species. We previously identified the antioxidant enzyme 2-Cys peroxiredoxin (PRX) in the raphidophyte Chattonella marina. This enzyme specifically decom...

Tributyltin (TBT) and polychlorinated biphenyls (PCBs) are typical organic pollutants that co-exist in the aquatic environment. Despite increasing awareness of their combined impacts, knowledge about their potential interactive effects remains limited. In this study, we investigated the effects of TBT-PCBs mixtures on the survival, development, and...

By combining photopolymerization method with surface imprinting techniques, the magnetic photocatalyst modified with the POPD-CdS heterojunction embedded imprinted layer (POPD-CdS heterojunction embedded magnetic imprinted photocatalyst) was successfully prepared. And ciprofloxacin (CIP) can be recognized and degraded by the POPD-CdS heterojunction...

In this study, an OJIP-test of two marine diatom species, Thalassiosira pseudonana (single-celled species) and Skeletonema marinoi-dohrnii complex (chain-forming species), were exposed to EC10 and EC50 levels of diuron and tributyltin (TBT) for 72 h. Increased tendency of relative fluorescence intensity (Ft/Fo value) at 300 μs and J step (2 ms) and...

https://authors.elsevier.com/c/1YJr7AOM9lXPN this paper can be downloaded freely within 50 days (before February 19, 2019), by clicking the above Share Link. The ubiquitous environmental obesogens tributyltin (TBT) and perfluorooctane sulfonate (PFOS) may accumulate in parent and be transferred to their offspring, resulting in trans-generational a...

The present study investigated how principal environmental factors such as temperature and light intensity change the toxicological properties of thiobencarb (TB) herbicide to the green alga, Raphidocelis subcapitata. At first, we investigated the inhibitory effect of TB (0, 15.6, 31.2, 62.4, and 125 μg L-1) on growth of R. subcapitata at five temp...

We investigated polycyclic aromatic hydrocarbon (PAH) pollution of the intertidal and supratidal zone using the wharf roach (Ligia sp.) as a novel environmental indicator. PAH and alkylated PAH (alkPAH) concentrations in wharf roaches collected from nine sampling sites on the central and northern coast of Japan in November 2011 were analyzed. Total...

Chlorpyrifos (CPF) is one of the most widely used insecticides and has been found in both urban and rural water bodies. In this study, we studied variations in the social behavioral patterns, swimming behavior, and brain acetylcholinesterase (AChE) activity of Japanese medaka exposed to lethal (0.12 mg/L) and sublethal (0.012 mg/L) concentrations o...

Bisphenol A (BPA) and di-n-butyl phthalate (DBP) are well-known endocrine-disrupting chemicals (EDCs) that have human health risks. Chronic exposure to BPA and DBP increases the occurrence of human disease. Despite the potential for exposure in embryonic development, the mechanism of action of BPA and DBP on vertebrate development and disease still...

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Time series variations in protein expression profiles in field Chattonella marina cells were investigated during a HAB occurred in the inner part of Ariake Sea, Japan (5-14 September, 2012). This study aimed to gather information on the molecular mechanisms underlying the physiological responses in field C. marina population during HAB. Proteomic a...

We exposed pen shells (Atrina lischkeana) to repeated periods of low-oxygen for 30 d and measured their survival, behavior, glycogen content, and organic acid concentration. Exposure to low-oxygen had no effect on survival. Animals moved upward above the sediment under low-oxygen conditions and downward under aerobic conditions, repeating these mov...

We investigated the gene structure and predicted amino acid sequence of the antioxidant enzyme 2-Cys peroxiredoxin (2-Cys Prx) in the raphidophyte Chattonella marina, which is a harmful algal bloom (HAB) species. The open reading frame of 2-Cys Prx was 585 bp long and encoded a protein consisting of 195 amino acids. The putative amino acid sequence...

Organisms in natural environments are often exposed to a broad variety of chemicals, and the multi-chemical mixtures exposure may produce significant toxic effects, even though the individual chemicals are present at concentrations below their no-observed-effect concentrations. This study represents the first attempt that uses the accelerated failu...

To provide an overview of anthropogenic contaminants in liquid organic fertilizers (LOFs), products from four biogas plants in Kyushu, Japan, were analyzed for a wide range of contaminants, including copper, cadmium, tributyltin (TBT), dibutyltin (DBT), perfluorooctane sulfonate, 952 semi-volatile organic compounds, and 89 antibiotics. The highest...

This study is the first to report sound production in Japanese medaka (Oryzias latipes). Sound production was affected by exposure to the carbamate insecticide (aldicarb) and heavy-metal compound (copper sulfate). Medaka were exposed at four concentrations (aldicarb: 0, 0.25, 0.5, and 1 mg L⁻¹; copper sulfate: 0, 0.5, 1, and 2 mg L⁻¹), and sound ch...

The present research investigated the effect of diuron on sinking rate and the physiochemical changes in two marine diatoms, Thalassiosira pseudonana (single-celled species) and Skeletonema marinoi-dohrnii complex (chain-forming species). The results revealed that the sinking rate of both diatoms exposed to diuron at a level of 50% effective concen...

We investigated the growth and chlorophyll-related parameters of the marine diatom Skeletonema marinoi-dohrnii complex （NIES-324） exposed to tributyltin （TBT） or photosystem （PS） II inhibitor Irgarol as a reference chemical for elucidating the effect of TBT on photosynthetic activity. Fifty percent effective concentrations for growth （EC50） were 2....

Benzo[c]phenanthrene (BcP) is a highly toxic polycyclic aromatic hydrocarbon (PAHs) found throughout the environment. In fish, it is metabolized to 3-hydroxybenzo[c]phenanthrene (3-OHBcP). In the present study, we observed the effects of 1 nM 3-OHBcP on the development and gene expression of Japanese medaka (Oryzias latipes) embryos. Embryos were n...

We evaluated the effects of calcium (Ca(2+)) and magnesium (Mg(2+)) ions on copper (Cu) toxicity to glochidia and newly-transformed juvenile mussels (age 1-2 days) of the Chinese pond mussel (Anodonta woodiana). Acute Cu toxicity tests were performed with glochidia for 24 h and juveniles for 96 h with measured Ca(2+) concentrations of 1.1, 14, 26,...

Time series variations in the potential maximum quantum yield of photosystem II (Fv/Fm ratio) and growth rate of field Chattonella marina cells were investigated during a HAB occurred in the inner part of Ariake Sea, Japan (5-14 September, 2012). This study aimed at investigating the usability of Fv/Fm ratio in evaluating the growth of C. marina an...

Radionuclide concentrations in wharf roaches inhabiting coastal areas of Honshu, Japan, were investigated in October 2011 and June 2012. Relative high concentrations of 110mAg (2.1–127 Bq kg-wet−1), 134Cs (2.6–61 Bq kg-wet−1), and 137Cs (3.5–92 Bq kg-wet−1) were detected in specimens from the eastern Honshu areas. Significantly lower 137Cs concentr...

This study was designed to determine the pharmacokinetics of (-)-Epigallocatechin gallate (EGCG) in yellowtail marine fish following oral gavage or intraperitoneal (IP) administration. After IP administration at a dose of 10 mg/kg body-weight, EGCG was detected in all plasma samples collected at 2 h post-dosing (2.22±1.46μg/ml). It was markedly low...

We investigated the allelopathic effects of Skeletonema spp. on growth and interspecific competition of the co-occurring flagellates Akashiwo sanguinea, Chattonella spp., and Heterosigma akashiwo, by reviewing field data on fluctuations in their cell densities and through laboratory experiments. From 29 June to 3 September, 2007, three dense blooms...

We investigated the effects of the herbicide thiobencarb on the growth, photosynthetic activity, and expression profile of photosynthesis-related proteins in the marine diatom Thalassiosira pseudonana. Growth rate was suppressed by 50% at a thiobencarb concentration of 1.26 mg/L. Growth and photosystem II activity (Fv /Fm ratio) were drastically de...