Xiaojun df Yan

• Professor at Ningbo University

The Kuroshio, the North Pacific Ocean's most robust western boundary current, brings a rich infusion of nutrients (especially phosphate) and warm‐water species into the East China Sea (ECS), profoundly shaping its environmental conditions and ecological processes. However, the precise impact of Kuroshio intrusion on the composition and distribution...

The diversity of fish coloration is a fascinating scientific question. The pawak croaker (Pennahia pawak) is distinguished by its silver-white colour, setting it apart from other Sciaenidae species. However, the genomic information of this genus remains largely unexplored. This study aims to advance our understanding by assembling and annotating th...

The aim of this study was to clarify the taxonomic identification of a hemoflagellate and assess the effect of trypanosome infection on Larimichthys crocea. Giemsa staining showed the presence of three morphotypes of trypomastigotes. The trypanosomes had the following morphological characteristics: a slender body with a long flagellum at the front;...

Dunaliella salina is an important source of natural β-carotene (containing 9-cis and all trans isomers) for industrial production. The phytohormone salicylic acid (SA) has been proven to have impacts on the stress resistance of higher plants, but research on microalgae is currently unclear. In this study, the effects of SA on the growth, biochemica...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by neuroinflammation and cognitive impairments. Although short-term treatment of fucoxanthin, a marine carotenoid with anti-neuroinflammation activity, was reported to prevent cognitive...

This study applied high-resolution satellite data to address the siting and evaluation challenges for potential cage aquaculture areas of large yellow croaker in Zhejiang Province. A typical template of water environmental factors for large yellow croaker cage aquaculture was developed, incorporating various environmental parameters and considerati...

Continuous cropping decreases soil nutrients and destroys microbial community structure, so the development of eco-friendly and effective biofertilizers is necessary under present conditions. In this study, the preserving microalgal strain Tribonema sp. (H) was firstly selected to be combined with agroforestry waste (shell powder, straw fermentatio...

Light sensitivity is important for marine benthic invertebrates, and it plays a vital role in the marine bivalves settling. Animal visual systems are enormously diverse; their development appears to be controlled by a set of conserved retinal determination genes (RDGs). Eyespots, as the simplest animal eyes, their appearance indicates the important...

The large yellow croaker, an endemic migratory species in China’s coastal waters, holds considerable economic importance. It is very necessary and significant to study the spatio-temporal evolution of large yellow croaker fishery based on environmental factors. In this paper, the HY-1C/D Coastal Zone Imager was applied to reveal distributional deta...

Chemokines play a crucial role in immune responses by facilitating the migration of cells expressing corresponding chemokine receptors along concentration gradients. Photobacterium damselae subsp. Damselae (PDD) and Nocardia seriolae (NS) are known to induce substantial mortality in silver pomfret populations, yet there exists a dearth of research...

There has been an emergence of a diversity of microalgal mixotrophic synergistic mechanisms due to substrate differences. In this study, the effects of the mixotrophic culture of Chlorella vulgaris were examined. The maximum values of cell density, specific growth rate, and cell dry weight of Chlorella vulgaris were 3.52*10⁷ cells/mL, 0.75 d⁻¹, and...

The growth and nutrients of photosynthetic organisms are significantly influenced by light spectra, yet this relationship is not well-understood in microalgae. Herein, we studied three microalgae species—Chaetoceros sp., Isochrysis galbana, and Tetraselmis helgolandica—distinguished by their pigments. We exposed them to seven light spectra, includi...

Lipoxygenases (LOXs) from lower organisms have substrate flexibility and function versatility in fatty acid oxidation, but it is not clear how these LOXs acquired the ability to execute multiple functions within only one catalytic domain. This work studied a multifunctional LOX from red alga Pyropia haitanensis (PhLOX) which combined hydroperoxidel...

Pampus argenteus is a highly commercial marine fish whose population is declining sharply. Here, we generated a female P. argenteus genome, spanning 536.33 Mb with contig N50 of 1.79 Mb; 24070 genes (99.50% of 24,182) were functionally annotated. To improve quality of it, we assembled a 553.79 Mb genome of male fish with contig N50 of 24.75 Mb thro...

Pampus argenteus demonstrates a preference for Rhopilema esculentum as prey, yet the ramifications of consuming supplemental medusa on fish microbiota and metabolism remain elusive. To elucidate these effects, 300 juvenile fish were divided into two groups: control group (C, given commercial food only) and supplemental medusa (SM) group (given supp...

Global fish production exceeds 170 million tons in 2023, and provides a high‐quality protein source for humans. However, various factors may contribute to hypoxic stress and anemia, which contribute to yield loss in fish production. Elevated red blood cell counts or activation of erythropoiesis are well‐known responses to anemia and hypoxia stress...

Isochrysis galbana is valuable in aquaculture due to its production of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). However, achieving high yields of polyunsaturated fatty acids (PUFAs) presents challenges, leading to exploration of innovative approaches. This study investigated the influence of Bacillus jeotgali on the growth of I....

Hatchery release of rock bream (Oplegnathus fasciatus) is common in the Zhoushan Sea region of the East China Sea as an efficient method for stock enhancement. Clarifying the genetic effects of farm-raised populations on wild ones is important for understanding the health of fish stocks. Thus, this study collected six rock bream stocks (two wild, t...

The razor clam Sinonovacula constricta, a commercially important and nutritionally valuable bivalve species, has been found to display notable responses to different light spectra. While previous research has highlighted the influence of light spectra on the growth, feeding rate, and various physiological characteristics of S. constricta, its impac...

Marine natural products offer a promising source in the development of new antibiotic drugs. Two previously undescribed compounds, including one sulfur-bearing alkaloid named quinosumycin (1) along with one chromone derivative namely chromycone (2), were discovered from an ethyl acetate (EtOAc) extract of marine Streptomyces diastaticus NBU2966 thr...

Fish skeletal muscle is composed of well-defined fiber types. In order to identify potential candidate genes affecting muscle growth and development under epigenetic regulation. Bisulfite sequencing was utilized to analyze and compare the muscle DNA methylation profiles of Larimichthys crocea inhabiting different environments. The results revealed...

The poly(butylene succinate-co-adipate) (PBSA) is emerging as environmentally sustainable polyester for applications in marine environment. In this work the capacity of microbiome associated with marine plankton culture to degrade PBSA, was tested. A taxonomic and functional characterization of the microbiome associated with the copepod Acartia ton...

Gamma-aminobutyric acid (GABA), widely existing in different organisms, is rapidly accumulated in plants in response to environmental stresses. The main biosynthesis and degradation pathways of GABA constitute the GABA shunt, which is tied to the tricarboxylic acid (TCA) cycle. GABA transaminase (GABA-T) and succinate semialdehyde dehydrogenase (SS...

Extracellular vesicles (EVs) are nano-sized particles involved in intercellular communications that intrinsically possess many attributes as a modern drug delivery platform. Haematococcus pluvialis-derived EVs (HpEVs) can be potentially exploited as a high-value-added bioproduct during astaxanthin production. The encapsulation of HpEV cargo is a cr...

Redox regulation is a fundamental physiological phenomenon related to oxygen-dependent metabolism, and skeletal muscle is mainly regarded as a primary site for oxidative phosphorylation. Several studies have revealed the importance of reactive oxygen and nitrogen species (RONS) in the signaling process relating to muscle adaptation during exercise....

Mussel aquaculture and large yellow croaker aquaculture areas and their environmental characteristics in Zhoushan were analyzed using satellite data and in-situ surveys. A new two-step remote sensing method was proposed and applied to determine the basic environmental characteristics of the best mussel and large yellow croaker aquaculture areas. Th...

Growth is a fundamental aspect of aquaculture breeding programs, pivotal for successful cultivation. Understanding the mechanisms that govern growth and development differences across various stages can significantly boost seedling production of economically valuable species, thereby enhancing aquaculture efficiency and advancing the aquaculture in...

Background Microalgae-derived extracellular vesicles (EVs), which transfer their cargos to the extracellular environment to affect recipient cells, play important roles in microalgal growth and environmental adaptation. And, they are also considered as sustainable and renewable bioresources of delivery nanocarrier for bioactive molecules and/or art...

Microalgae are considered to be natural producers of bioactive pigments, with the production of pigments from microalgae being a sustainable and economical strategy that promises to alleviate growing demand. Chlorophyll, as the main pigment of photosynthesis, has been widely studied, but its medicinal applications as an antioxidant, antibacterial,...

Fucoxanthin, a natural carotenoid that has substantial pharmaceutical value due to its anticancer, antioxidant, antiobesity, and antidiabetic properties, is biosynthesized from glyceraldehyde‐3‐phosphate (G3P) via a series of enzymatic reactions. However, our understanding of the transcriptional mechanisms involved in fucoxanthin biosynthesis remai...

Copepods are the most abundant organisms in marine zooplankton and the primary components of the food chain. They are hotspots for highly adaptable microorganisms, which are pivotal in biogeochemical cycles. The microbiome, encompassing microorganisms within and surrounding marine planktonic organisms, holds considerable potential for biotechnologi...

Phototransduction is based on opsins that drive distinct types of Gα cascades. Although nonvisual photosensitivity has long been known in marine bivalves, the underlying molecular basis and phototransduction mechanism are poorly understood. Here, we introduced the eyeless razor clam Sinonovacula constricta as a model to clarify this issue. First, w...

The nuclear factor erythroid 2-related factor 2 (Nrf2) is a pivotal regulator of antioxidant gene expression in mammals, forming heterodimer complexes with small Maf proteins through its BZip domain. However, the underlying mechanism of Nrf2 action in molluscs remains poorly understood. The thick shell mussel, Mytilus coruscus, represents a model o...

Mytilus coruscus is an economically important marine bivalve mollusk found in the Yangtze River estuary, which experiences dramatic pH fluctuations due to seasonal freshwater input and suffer from shell fracture or injury in the natural environment. In this study, we used intact-shell and damaged-shell M. coruscus and performed metabolomic analysis...

Mytilus coruscus is an economically important marine calcifier living in the Yangtze River estuary sea area, where seasonal fluctuations in natural pH occur owing to freshwater input, resulting in a rapid reduction in seawater pH. In addition, Mytilus constantly suffers from shell fracture or injury in the natural environment, and the shell repair...

To effectively utilize the by-products of skipjack tuna (Katsuwonus Pelamis) for the preparation of peptides with lipid-lowering activity, alkaline proteinase was selected from six commercial proteases to hydrolyze dark muscle. An L16 (5⁴) orthogonal design was employed to optimize the hydrolysis conditions, resulting in the production of a high-pe...

Compensatory growth (CG) in fish is heavily influenced by nutrient metabolism. However, there are limited studies examining how nutrient metabolism is regulated during this process. For silver pomfret, an important commercial marine fish, it's crucial to establish effective starvation and re-feeding strategies to ensure good water quality and fast...

The hard-shell mussel (Mytilus coruscus) is widespread in the temperate coastal areas of the northwest Pacific and holds a significant position in the shellfish aquaculture market in China. However, the natural resources of this species have been declining, and population genetic studies of M. coruscus are also lacking. In this study, we conducted...

We cultured silver pomfret for 20 days, decreasing water temperature from 18 to 8 ℃, and sampled muscle every 5 days. Muscle fiber degeneration and apoptosis began to increase at 13 ℃ detected by HE and TUNEL staining. Further analysis of transcriptome revealed that several apoptosis-related pathways were highly enriched by differentially expressed...