Xiaojun Chen

Xiaojun Chen
Shanghai Jiao Tong University | SJTU · Department of Mechanical Engineering (ME)

Professor

About

146
Publications
29,611
Reads
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1,854
Citations
Citations since 2016
104 Research Items
1707 Citations
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
20162017201820192020202120220100200300400
Introduction
Additional affiliations
December 2018 - present
Shanghai Jiao Tong University
Position
  • Professor
Description
  • His research focuses on biomedical engineering and computer assisted surgery, including biomedical image analysis, image-guided interventions, artificial intelligence in biomedical physics and analysis, VR/AR/MR technology in medicine, medical robotics, biomedical manufacturing, etc.

Publications

Publications (146)
Article
PurposeFree fibula flap is the gold standard for the treatment of mandibular defects. However, the existing preoperative planning protocol is cumbersome to execute, costly to learn, and poorly collaborative with the robot-assisted cutting of the fibular osteotomy plane.MethodsA surgical planning system for robotic assisted mandibular reconstruction...
Preprint
Full-text available
Fibula osteotomy needs to be performed precisely and safely in mandibular reconstruction with free fibula flap (FFF). However, current clinical methods, such as template-guided osteotomy, have potential for damage to fibular vessels. To address the challenge, this paper introduces the development of the surgical robot for fibula osteotomies in mand...
Article
As the number of people suffering from cardiovascular diseases increases every year, it becomes essential to have an accurate automatic electrocardiogram (ECG) diagnosis system. Researchers have adopted different methods, such as deep learning, to investigate arrhythmias classification. However, the importance of ECG waveform features is generally...
Article
Introduction With the widespread availability of portable electrocardiogram (ECG) devices, there will be a surge in ECG diagnoses. Traditional computer-aided diagnosis of arrhythmia mainly relies on the rules of medical knowledge, which are insufficient due to the limitations of data quality and human expert knowledge. The research of arrhythmia de...
Article
Full-text available
Head and neck surgery is a fine surgical procedure with a complex anatomical space, difficult operation and high risk. Medical Image Computing (MIC) that enables accurate and reliable preoperative planning is often needed to reduce the operational difficulty of surgery and to improve patient survival. At present, Artificial Intelligence (AI), espec...
Conference Paper
There are inevitable risks during zygomatic implant placement surgery, particularly due to the complex anatomical structure of the zygomatic maxillary and the limited operating space. In this study, we present a haptic based simulation system for trainees to rehearse the process of zygomatic implant placement surgery, providing them with a multi-di...
Article
Objectives To compare the accuracy of dental implant placement using dynamic navigation system and robotic systems. Methods Eighty three-dimensional (3D) printed phantoms, including edentulous and partially edentulous jaws, were assigned to two groups: a dynamic navigation system (Beidou-SNS) group and a robotic system (Hybrid Robotic System for D...
Article
Full-text available
Purpose: Precise determination of target is an essential procedure in prostate interventions, such as prostate biopsy, lesion detection, and targeted therapy. However, the prostate delineation may be tough in some cases due to tissue ambiguity or lack of partial anatomical boundary. In this study, we proposed a novel supervised registration-based...
Article
Purpose: Reverse shoulder arthroplasty (RSA) is an effective surgery for severe shoulder joint diseases. Traditionally, the preoperative planning procedure of RSA is manually conducted by experienced surgeons, resulting in prolonged operating time and unreliable drilling paths of the prosthetic fixation screws. In this study, an automatic surgical...
Article
Objective: Cervical pedicle screw (CPS) placement surgery remains technically demanding due to the complicated anatomy with neurovascular structures. State-of-the-art surgical navigation or robotic systems still suffer from the problem of hand-eye coordination and soft tissue deformation. In this study, we aim at tracking the intraoperative soft t...
Article
Full-text available
Objective To realize the three-dimensional visual output of surgical navigation information by studying the cross-linking of mixed reality display devices and high-precision optical navigators. Methods Applying quaternion-based point alignment algorithms to realize the positioning configuration of mixed reality display devices, high-precision opti...
Article
Full-text available
In traditional orthognathic surgery, the dental splint technique is typically used to assist surgeons to reposition the maxilla or mandible. However, the design and manufacturing of dental splints is time-consuming and labor-intensive, and the templates may not applicable for some complicated cases due to the anatomic intricacies in the maxillofaci...
Article
Full-text available
In this article, we present a skull database containing 500 healthy skulls segmented from high-resolution head computed-tomography (CT) scans and 29 defective skulls segmented from craniotomy head CTs. Each healthy skull contains the complete anatomical structures of human skulls, including the cranial bones, facial bones and other subtle structure...
Article
Real-time augmented reality (AR) for minimally invasive surgery without extra tracking devices is a valuable yet challenging task, especially considering dynamic surgery environments. Multiple different motions between target organs are induced by respiration, cardiac motion or operative tools, and often must be characterized by a moving, manually...
Article
Mandibular reconstruction is a very complex surgery that demands removing the tumor and reconstructs the defective mandible. Accurate segmentation of the mandible plays an important role in its preoperative planning. However, there are many segmentation challenges including the connected boundaries of upper and lower teeth, blurred condyle edges, m...
Article
Background The accurate distal locking of intramedullary (IM) nails is a clinical challenge for surgeons. Although many navigation systems have been developed, a real-time guide method with free radiation exposure, better user convenience, and high cost performance has not been proposed. Methods This paper aims to develop an electromagnetic naviga...
Article
Patient-specific mandibular reconstruction plate (PSMRP), as one of the patient-specific implants (PSIs), offers a host of benefits to mandibular reconstruction. Due to the limitation of fabricating screw hole threads in the PSMRP, 3D printed PSMRP is applied to the non-locking system directly in the mandibular reconstruction with bone graft regard...
Article
PurposeDental implant surgery is an effective method for remediating the loss of teeth. Robot is expected to increase the accuracy of dental implant surgery. However, most of them are industrial serial robot, with low stiffness and non-unique inverse kinematic solution, which may reduce the success rate and safety of robotic surgery. Compared to se...
Article
Introduction: Researchers and engineers have found their importance in healthcare industry including recent updates in patient-specific implant (PSI) design. CAD/CAM technology played an important role in the design and development of Artificial Intelligence (AI) based implants. The across the globe have their interest focused on the design and man...
Article
Purpose: In cranio-maxillofacial surgery, it is of great clinical significance to segment mandible accurately and automatically from CT images. However, the connected region and blurred boundary in teeth and condyles make the process challenging. At present, the mandible is commonly segmented by experienced doctors using manually or semi-automatic...
Article
A fast and fully automatic design of 3D printed patient-specific cranial implants is highly desired in cranioplasty - the process to restore a defect on the skull. We formulate skull defect restoration as a 3D volumetric shape completion task, where a partial skull volume is completed automatically. The difference between the completed skull and th...
Article
Virtual reality-based surgery simulation is becoming popular with the development of minimally invasive abdominal surgery, where deformable soft tissue is modelled and simulated. The mass-spring model (MSM) and finite element method (FEM) are common methods used in the simulation of soft tissue deformation. However, MSM has an issue concerning accu...
Article
Sinus floor elevation with a lateral window approach requires bone graft (BG) to ensure sufficient bone mass, and it is necessary to measure and analyse the BG region for follow-up of postoperative patients. However, the BG region from cone-beam computed tomography (CBCT) images is connected to the margin of the maxillary sinus, and its boundary is...
Article
The aim of this paper is to provide a comprehensive overview of the MICCAI 2020 AutoImplant Challenge1. The approaches and publications submitted and accepted within the challenge will be summarized and reported, highlighting common algorithmic trends and algorithmic diversity. Furthermore, the evaluation results will be presented, compared and dis...
Article
Background and Objective The distal interlocking of intramedullary nail remains a technically demanding procedure. Existing augmented reality based solutions still suffer from hand-eye coordination problem, prolonged operation time, and inadequate resolution. In this study, an augmented reality based navigation system for distal interlocking of int...
Article
Full-text available
The patient‐specific templates for osteotomy often have complex surface features. Using current commercial software to design such templates is quite complicated, tedious and unrepeatable. In this study, a novel surgical planning system for oral and maxillofacial surgery named EasyTemplate is developed, aiming to help doctors shorten the modeling t...
Article
Full-text available
Background: Dental implant placement navigation systems based on optical tracking have been widely used in clinics. However, Electromagnetic (EM) navigation method that does not suffer from problems of hidden line-of-light has not yet been described. Methods: This work proposes an EM-guided navigation method named TianShu-ESNS with virtual calibra...
Article
Background: Research proves that the apprenticeship model, which is the gold standard for training surgical residents, is obsolete. For that reason, there is a continuing effort toward the development of high-fidelity surgical simulators to replace the apprenticeship model. Applying Virtual Reality Augmented Reality (AR) and Mixed Reality (MR) in s...
Chapter
Cranial implant design can be thought as a 3D shape completion task predicting the missing part of a defective cranium, which is a time-consuming task in traditional methods. This paper proposes a deep convolutional neural network (CNN) based method which predicts the implant from a binary voxel image of a defective skull. Three networks with the s...
Conference Paper
Full-text available
Zygomatic implant technology has been successfully applied to the repair of atrophic maxilla to avoid a large number of grafting surgery and shorten the recovery time. However, because of the long trajectories of zygomatic implant placement, the destruction of normal anatomical landmark and the narrow operating space, it is difficult to operate and...
Article
Purpose: The use of an optical see-through head-mounted display (OST-HMD) in augmented reality (AR) has significantly increased in recent years, but the alignment between the virtual scene and physical reality is still a challenge. A fast and accurate calibration method of OST-HMD is important for augmented reality in the medical field. Methods:...
Article
Full-text available
PurposeRobot-world calibration, used to precisely determine the spatial relation between optical tracker and robot, is regarded as an essential step for optical-navigated surgical robot system to improve the surgical accuracy. However, these methods are complicated with numerous computation. Therefore, a more efficient method of a robot-world calib...
Preprint
Precise determination of target is an essential procedure in prostate interventions, such as the prostate biopsy, lesion detection and targeted therapy. However, the prostate delineation may be tough in some cases due to tissue ambiguity or lack of partial anatomical boundary. To address this problem, we proposed a weakly supervised registration-ba...
Article
PurposeThe analysis of the maxillary sinus (MS) can provide an assessment for many clinical diagnoses, so accurate CT image segmentation of the MS is essential. However, common segmentation methods are mainly done by experienced doctors manually, and there are some challenges such as low efficiency and precision. As for automatic methods, the initi...
Article
Aortic dissection (AD) is a condition of the main artery of the human body, resulting in the formation of a new flow channel, or false lumen. The disease is usually diagnosed with a computed tomography angiography scan during the acute phase. A better understanding of the causes of AD requires knowledge of the aortic geometry (segmentation), includ...
Article
The porous structure of the implant contributes significantly to prosthetic osseointegration in cranio‐maxillofacial defect repair surgeries.this study establishes a system called EasyImplant that can easily and efficiently design customized cranio‐maxillofacial implant with porous structure.Healthy side of the skull model is used to obtain the ini...
Article
Introduction: Various prefabricated maxillofacial implants are used in the clinical routine for the surgical treatment of patients. In addition to these prefabricated implants, customized CAD/CAM implants become increasingly important for a more precise replacement of damaged anatomical structures. This paper reviews the design and manufacturing of...
Poster
Full-text available
Given underlying computer simulations, this work provides a way to visualize Aortic Dissection (AD) in a realistic manner. Based on Virtual Reality (VR), the solution provides a visual user experience that is immersive: while conservative methods might require a researcher to sight a huge amount of medical images, VR allows the researcher to examin...
Conference Paper
Full-text available
The human organism is a highly complex system that is prone to various diseases. Some diseases are more dangerous than others, especially those that affect the circulatory system or the aorta in particular. The aorta is the largest artery in the human body. Its wall comprises several layers. When the intima, i.e. the innermost layer of the aortic w...
Conference Paper
Volumetric examinations of the aorta are nowadays of crucial importance for the management of critical pathologies such as aortic dissection, aortic aneurism, and other pathologies, which affect the morphology of the artery. These examinations usually begin with the acquisition of a Computed Tomography Angiography (CTA) scan from the patient, which...
Article
Full-text available
With age, our blood vessels are prone to aging, which induces cardiovascular disease. As an important basis for diagnosing heart disease and evaluating heart function, the electrocardiogram (ECG) records cardiac physiological electrical activity. Abnormalities in cardiac physiological activity are directly reflected in the ECG. Thus, ECG research i...
Article
Full-text available
Medical augmented reality (AR) is an increasingly important topic in many medical fields. AR enables x-ray vision to see through real world objects. In medicine, this offers pre-, intra- or post-interventional visualization of “hidden” structures. In contrast to a classical monitor view, AR applications provide visualization not only on but also in...
Article
Full-text available
This paper presents a high precision and low computational complexity premature ventricular contraction (PVC) assessment method for the ECG human-machine interface device. The original signals are preprocessed by integrated filters. Then, R points and surrounding feature points are determined by corresponding detection algorithms. On this basis, a...
Article
Purpose Analyses of the morphology of proximal femora are essential for preoperative planning and designing customized femoral stems in total hip arthroplasty as well as intramedullary nailing fixation. Various studies reported measurements and analyses on the general geometry of proximal femora three-dimensionally. However, the modeling and measur...
Article
Full-text available
Zygomatic implant technology has been regarded as an alternative treatment to massive grafting surgery in the severe atrophic maxillary. Nowadays, the assistant method with a real-time surgical navigation has been applied to reduce the risks of zygomatic implant placement. However, the accuracy of the complex operation is highly dependent on the ex...
Article
Introduction: At present, cancer imaging examination relies mainly on manual reading of doctors, which requests a high standard of doctors’ professional skills, clinical experience and concentration. However, the increasing amount of medical imaging data has brought more and more challenges to radiologists. The detection of digestive system cancer...
Article
Purpose Image-guided surgical navigation system (SNS) has proved to be an increasingly important assistance tool for mini-invasive surgery. However, using standard devices such as keyboard and mouse as human–computer interaction (HCI) is a latent vector of infectious medium, causing risks to patients and surgeons. To solve the human–computer intera...
Article
Full-text available
In practice, 3D modelling software, such as UG and Pro/E, are commonly adopted to design porous scaffolds within given contours. However, this manual method is quite time‐consuming and complicated with poor adaptability. In this study, a novel facial algorithm is proposed for smart scaffold design. By forming a dendritic fractal network, the second...
Article
Full-text available
Purpose Surgical navigation system (SNS) has been an important tool in surgery. However, the complicated and tedious manual selection of fiducial points on preoperative images for registration affects operational efficiency to large extent. In this study, an oral and maxillofacial navigation system named BeiDou-SNS with automatic identification of...
Article
Purpose In the dental implant surgery, there are inevitable risks due to the anatomically complex operation in the cranio-maxillofacial region. Therefore, there is a trend to use computer-aided technology to simulate the process of the implant surgery. In this study, we present a haptic simulator for trainees to study and rehearse the drilling perf...
Article
Introduction: Traditional medical training in oral and maxillofacial surgery may be limited by its low efficiency and high price due to the shortage of cadaver resources. With the combination of visual rendering and feedback force, surgery simulators become increasingly popular in hospitals and medical schools as an alternative to the traditional t...
Article
Full-text available
Introduction Computer assisted technologies based on algorithmic software segmentation are an increasing topic of interest in complex surgical cases. However—due to functional instability, time consuming software processes, personnel resources or licensed-based financial costs many segmentation processes are often outsourced from clinical centers t...
Article
Full-text available
Optical coherence tomography (OCT) has been widely applied to the diagnosis of eye diseases during the past two decades. However, valid evaluation methods are still not available for the clinical OCT devices. In order to assess the axial resolution of the OCT system, standard model eyes with micro-scale multilayer structure have been designed and m...
Chapter
Over the past decades, the surgical guides or templates as the high-precision technologic tools have been applied for various surgeries such as the oral implantology, oncology, nasal prosthesis implant placement, cervical or lumbar pedicle screw placement, total hip arthroplasty (THA), treatment of sacroiliac joint fracture, total knee arthroplasty...
Article
Accurately determining the spatial relationship between the pelvis and acetabulum is challenging due to their inherently complex three-dimensional (3D) anatomy. A standardized 3D pelvic coordinate system (PCS) and the precise assessment of acetabular orientation would enable the relationship to be determined. We present a surface-based method to es...
Article
Full-text available
Spinal diseases are very common; for example, the risk of osteoporotic fracture is 40% for White women and 13% for White men in the United States during their lifetime. Hence, the total number of surgical spinal treatments is on the rise with the aging population, and accurate diagnosis is of great importance to avoid complications and a reappearan...
Conference Paper
Apart from the applications in surgical navigations, virtual surgery has become a new feasible method for training young surgeons. Since 2006 virtual simulation has been performed in selected patient cases affected by complex craniomaxillofacial disorders (n = 8) in addition to standard surgical planning based on patient specific 3d-models. Althoug...
Conference Paper
The haptic-based virtual reality simulation which can create a visual and tactile fusion in virtual environment for operators is an important application in surgical training. The catheter’s deformation and force feedback are key techniques in the catheter interventional simulator. The simulation of catheter interventional surgery is developed with...
Poster
Full-text available
Apart from the applications in surgical navigations, virtual surgery has become a new feasible method for training young surgeons. Since 2006 virtual simulation has been performed in selected patient cases affected by complex craniomaxillofacialdisorders (n = 8) in addition to standard surgical planning based on patient specific 3d-models. Although...
Poster
Full-text available
Augmented Reality (AR)-guided intraoperative Navigation
Conference Paper
Full-text available
The manual outlining of hepatic metastasis in (US) ultrasound acquisitions from patients suffering from pancreatic cancer is common practice. However, such pure manual measurements are often very time consuming, and the results repeatedly differ between the raters. In this contribution, we study the in-depth assessment of an interactive graph-based...
Article
Full-text available
In this contribution, a software system for computer-aided position planning of miniplates to treat facial bone defects is proposed. The intra-operatively used bone plates have to be passively adapted on the underlying bone contours for adequate bone fragment stabilization. However, this procedure can lead to frequent intra-operatively performed ma...