Xiao Liu

University of Adelaide · School of Electrical and Electronic Engineering

Objective To investigate the effect of adenotonsillectomy on OSAS symptoms based on a data-driven approach and thereby identify criteria that may help avoid unnecessary surgery in children with OSAS.Methods In 323 children enrolled in the Childhood Adenotonsillectomy Trial, randomised to undergo either early adenotonsillectomy (eAT; N = 165) or a s...

Sleep disordered breathing (SDB) is a common pediatric disorder, which results in increasing respiratory workload during sleep, restless night time sleep and excessive daytime sleepiness. It has significant negative effects on children with SDB on their physical growth and cognitive related developments. Chronic autonomic activation was suggested t...

Objective To assess the effect of adenotonsillectomy for relieving OSAS symptoms in children on cardiac autonomic modulation. Methods In 354 children enrolled in the Childhood Adenotonsillectomy Trial, randomized to undergo either early adenotonsillectomy (eAT; N=181) or a strategy of watchful waiting with supportive care (WWSC; N=173), nocturnal...

Study objectives To assess cardiovascular control during sleep in children with sleep disordered breathing (SDB) and the effect of adenotonsillectomy in comparison to healthy non-snoring children. Methods Cardiorespiratory signals obtained from overnight polysomnographic recordings (PSG) of 28 children with SDB and 34 healthy non-snoring children...

The efficacy of adenotonsillectomy for treating obstructive sleep apnoea syndrome (OSAS) in children has been established, but its precise effects on inspiratory effort are not well documented. In 353 children enrolled in the Childhood Adenotonsillectomy Trial, randomised to undergo either early adenotonsillectomy (n=182) or a strategy of watchful...