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Xabier Vázquez-Campos

Xabier Vázquez-Campos
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Xabier verified their affiliation via an institutional email.
UNSW Sydney | UNSW · School of Biotechnology and Biomolecular Sciences (BABS)

PhD

About

55
Publications
90,499
Reads
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952
Citations
Introduction
My research interests are focused mainly in the microbiology implied in environmental processes such biomineralisation, redox transformations, or the degradation of pollutants either in natural or engineered systems, with special interest on extremophiles. From metabolic processes to community functioning, taxonomic novelties and new culturing methods. Also interested in astrobiology.
Additional affiliations
January 2023 - July 2023
UNSW Sydney
Position
  • Casual Research Assistant
January 2022 - December 2022
UNSW Sydney
Position
  • Senior Research Associate
February 2017 - December 2021
UNSW Sydney
Position
  • Research Associate
Education
July 2011 - March 2015
UNSW Sydney
Field of study
  • Civil and Environmental Engineering
October 2007 - September 2008
Autonomous University of Madrid
Field of study
  • Microbiology
September 2005 - July 2007
University of Vigo
Field of study
  • Biotechnology

Publications

Publications (55)
Article
Full-text available
Seven acidophilic/acidotolerant fungal strains were characterized from samples of process waters (raffinate) at one of Australia's largest uranium mines, the Ranger Mine in Northern Territory. They were isolated from raffinate, which typically were very acidic (pH 1.7-1.8) and contained high concentrations of total dissolved/colloidal salts (> 100...
Article
Full-text available
The uptake and binding of uranium [as (UO2)2+] by a moderately acidophilic fungus, Coniochaeta fodinicola, recently isolated from a uranium mine site, is examined in this work in order to better understand the potential impact of organisms such as this on uranium sequestration in hydrometallurgical systems. Our results show that the viability of th...
Article
Full-text available
During the 1960s, small quantities of radioactive materials were co-disposed with chemical waste at the Little Forest Legacy Site (LFLS, Sydney, Australia). The microbial function and population dynamics in a waste trench during a rainfall event have been previously investigated revealing a broad abundance of candidate and potentially undescribed t...
Article
Full-text available
Recent discoveries of isoprene-metabolizing microorganisms suggest they might play an important role in the global isoprene budget. Under anoxic conditions, isoprene can be used as an electron acceptor and is reduced to methylbutene. This study describes the proteogenomic profiling of an isoprene-reducing bacterial culture to identify organisms and...
Article
Significant recent advances in structural biology, particularly in the field of cryoelectron microscopy, have dramatically expanded our ability to create structural models of proteins and protein complexes. However, many proteins remain refractory to these approaches because of their low abundance, low stability, or-in the case of complexes-simply...
Article
Translation elongation factor 1A (eEF1A) is an essential and highly conserved protein required for protein synthesis in eukaryotes. In both Saccharomyces cerevisiae and human, five different methyltransferases methylate specific residues on eEF1A, making eEF1A the eukaryotic protein targeted by the highest number of dedicated methyltransferases aft...
Article
Background: Despite compositional alterations in gastrointestinal microbiota being purported to underpin some of the therapeutic effects of ginger, the effect of a standardized ginger supplement on gut microbiota has not been tested in humans. Aims: To determine the effect of a standardized ginger (Zingiber officinale) root powder, compared to p...
Article
Full-text available
Dichloromethane (DCM; CH 2 Cl 2 ) is a widespread pollutant with anthropogenic and natural sources. Anaerobic DCM-dechlorinating bacteria use the Wood–Ljungdahl pathway, yet dechlorination reaction mechanisms remain unclear and the enzyme(s) responsible for carbon-chlorine bond cleavage have not been definitively identified. Of the three bacterial...
Preprint
Full-text available
Recent discoveries of isoprene-metabolizing microorganisms suggest they might play an important role in the global isoprene budget. Under anoxic conditions, isoprene can be used as an electron acceptor and is reduced to methylbutene. This study describes the proteogenomic profiling of an isoprene-reducing bacterial culture to identify organisms and...
Preprint
Full-text available
Significant recent advances in structural biology, particularly in the field of cryo-electron microscopy, have dramatically expanded our ability to create structural models of proteins and protein complexes. However, many proteins remain refractory to these approaches because of their low abundance, low stability or - in the case of complexes - sim...
Article
Numerous legacy near-surface radioactive waste sites dating from the mid 20th century have yet to be remediated and present a global contamination concern. Typically, there is insufficient understanding of contaminant release and redistribution, with invasive investigations often impractical due to the risk of disturbing the often significantly rad...
Article
Full-text available
Background This study examines longitudinal bio-psychological dynamics and their interplay in IBD patients undergoing conventional and biological therapies. Methods Fifty IBD participants (24 UC, 26 CD) in clinical remission were followed for 12 months. Complete longitudinal datasets, biological samples, validated scores of psychological status we...
Article
Full-text available
Recent acknowledgment that multidrug resistant Stenotrophomonas maltophilia strains can cause severe infections has led to increasing global interest in addressing its pathogenicity. While being primarily associated with hospital-acquired respiratory tract infections, this bacterial species is also relevant to ophthalmology, particularly to contact...
Article
Results of investigations into factors influencing contaminant mobility in a replica trench located adjacent to a legacy radioactive waste site are presented in this study. The trench was filled with nonhazardous iron- and organic matter (OM)-rich components, as well as three contaminant analogues strontium, cesium, and neodymium to examine contami...
Article
Background Therapeutic aims in IBDs are to induce remission through rapidly effective treatment. Conventional therapeutic methods including immunosuppression have been available for more than half a century with biological therapies the treatment of choice in patients who fail immunosuppressive drugs. There has been little attempt to longitudinally...
Article
Full-text available
Biological soil crusts or biocrusts have critical ecological roles in dryland ecosystems including soil stabilization, erosion control and nutrient cycling. Global environmental changes are expected to impact terrestrial ecosystems, including biocrust communities. Thus, a growing number of studies have focused on investigating the diversity of bioc...
Article
Big data abound in microbiology, but the workflows designed to enable researchers to interpret data can constrain the biological questions that can be asked. Five years after anvi’o was first published, this community-led multi-omics platform is maturing into an open software ecosystem that reduces constraints in ‘omics data analyses.
Article
Full-text available
The polyphyletic group of black fungi within the Ascomycota (Arthoniomycetes, Dothideomycetes, and Eurotiomycetes) is ubiquitous in natural and anthropogenic habitats. Partly because of their dark, melanin-based pigmentation, black fungi are resistant to stresses including UV-and ionizing-radiation, heat and desiccation, toxic metals, and organic p...
Article
Full-text available
Background: Repetitive-PCR (rep-PCR) using BOXA1R and BOXA2R as single primers was investigated for its potential to genotype bacteriophage. Previously, this technique has been primarily used for the discrimination of bacterial strains. Reproducible DNA fingerprint patterns for various phage types were generated using either of the two primers. R...
Article
Background Therapeutic aims in IBDs are to induce remission through rapidly effective treatment. Conventional therapeutic methods including immunosuppression have been available for more than half a century with biological therapies the treatment of choice in patients who fail immunosuppressive drugs. There has been little attempt to longitudinally...
Preprint
Full-text available
During the 1960s, small quantities of radioactive materials were co-disposed with chemical waste at the Little Forest Legacy Site (LFLS, Sydney, Australia). The microbial function and population dynamics during a rainfall event using shotgun metagenomics has been previously investigated. This revealed a broad abundance of candidate and potentially...
Article
Background While there is a literature suggesting associations between gut microbiota, physiological factors, psychological state, immune modulation and IBD, there has been little attempt to integrate these factors over time and assess their interdependence with IBD disease activity. This study pursued longitudinal monitoring in IBD, examining inte...
Data
Coloured figures for the paper: Disentangling the drivers of functional complexity at the metagenomic level in Shark Bay microbial mat microbiomes
Article
Full-text available
The functional metagenomic potential of Shark Bay microbial mats was examined for the first time at a millimeter scale, employing shotgun sequencing of communities via the Illumina NextSeq 500 platform in conjunction with defined chemical analyses. A detailed functional metagenomic profile has elucidated key pathways and facilitated inference of cr...
Article
Full-text available
During the 1960s, small quantities of radioactive materials were codisposed with chemical waste at the Little Forest Legacy Site (Sydney, Australia) in 3-meter-deep, unlined trenches. Chemical and microbial analyses, including functional and taxonomic information derived from shotgun metagenomics, were collected across a 6-week period immediately a...
Preprint
During the 1960s, small quantities of radioactive materials were co-disposed with chemical waste at the Little Forest Legacy Site (Sydney, Australia) in three-metre-deep, unlined trenches. Chemical and microbial analyses, including functional and taxonomic information derived from shotgun metagenomics, were collected across a six-week period immedi...
Article
The biogeochemistry of the acid leaching of a non-sulfidic, weathered uranium ore from Ranger Mine (Australia) in relation to varied iron concentrations and Fe(III)/Fe(II) ratios was examined in this work. Controlled column studies which simulate a heap-leaching process, showed rapid uranium leaching during the initial stages of operation. This was...
Thesis
Full-text available
Microorganisms are everywhere. Anthropogenic industrial environments are no exception, even when operating under extreme conditions. The mining of uranium by acid-leaching creates a suitable habitat for those organisms unconstrained by such conditions. This thesis approaches relevant aspects of the microbiology thriving in such systems and the pote...
Article
Full-text available
X. (2015): Acidotolerant genus Fodino-myces (Ascomycota: Capnodiales) is a synonym of Acidiella. – Czech Mycol. 67(1): 37–38. A new combination, Acidiella uranophila (X. Vázquez-Campos) M. Kolařík, Hujslová & X. Vázquez-Campos is provided for Fodinomyces uranophilus X. Vázquez-Campos based on similarity in phenotype and genotype. X. (2015): Acidoto...
Conference Paper
Full-text available
Although the presence of fungi in acidic mining systems has been widely established and attention paid to the problems created by their growth, limited consideration has been given to their role in community functioning. Seven acidophilic/acid-tolerant fungal strains were characterised from the process waters at one of Australia's largest uranium m...
Article
Full-text available
In the present work, several samples from lab waste containers polluted with polycyclic aromatic hydrocarbons (PAHs) and heavy metals were investigated as potential sources of PAH-degrading microorganisms. After isolating, two fungal strains were selected as the best degrading microorganisms. Genetic identification by sequencing was carried out and...
Article
Full-text available
La lixiviación microbiana o biolixiviación es un proceso mediante el cual, utilizando microorganismos, se extraen los metales a partir de las rocas que los contienen. Consiste en la conversión de un metal insoluble, normalmente en forma de sulfuro, en una forma soluble, normalmente como sulfato. Es un proceso complejo llevado por una comunidad micr...

Questions

Questions (11)
Question
We've done metaproteomics on a very simple enrichment culture (2 spp.) for differential expression. The data analysis basically shows functional changes in the community as a whole. Some reviewers have been suggesting us to partition the data and split the analysis between the 2 spp. in the system so we can evaluate the different responses of each organism without the bias introduced by changes in the community (there is an important change in the proportions of the 2 spp in the treatment vs control). Any takes on this? Would that really be appropriate?
PD: I've seen something called taxon-specific normalisation that it's supposed to remove this bias in metatranscriptomic data, any experience on that?

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