Willem Ravensberg

Willem Ravensberg
Koppert B.V. · Regulatory Affairs

PhD

About

42
Publications
8,510
Reads
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1,967
Citations
Additional affiliations
January 2013 - December 2015
Koppert Biological Systems
Position
  • Governmental and Regulatory Affairs Manager

Publications

Publications (42)
Chapter
Microbial bioprotectants have the potential to play a major role in the future of crop protection. Agriculture needs to become more sustainable and still provide food security within planetary borders. New technologies and scientific discoveries can unravel the interactions between the plant, the microbiome and the soil and provide new opportunitie...
Chapter
Microbial bioprotectants, like chemical pesticides, are required to pass a risk assessment and risk management procedure prior to use in plant protection, which in many countries is an obstacle for market access, in particular, the European Union. Administrative issues and data requirements, adapted from those used for chemicals, cause issues for b...
Chapter
First we describe the different types of biocontrol used in greenhouses and present examples of each type. Next we summarize the history of greenhouse biocontrol, which started in 1926, showed a problematic period when synthetic chemical pesticides became available after 1945, and flourished again since the 1970s. After 1970, the number of natural...
Article
Full-text available
Microbial biological control agents (MBCAs) against pests and diseases in crops are regarded as sustainable tools in integrated pest management. In the European Union, biological control should be preferred to conventional chemical methods if they provide satisfactory pest reduction. There is no reason to believe that all forms of biocontrol are in...
Article
Full-text available
Microbial biological control agents (MBCAs) are applied to crops for biological control of plant pathogens where they act via a range of modes of action. Some MBCAs interact with plants by inducing resistance or priming plants without any direct interaction with the targeted pathogen. Other MBCAs act via nutrient competition or other mechanisms mod...
Article
Full-text available
In augmentative biological control (ABC), invertebrate and microbial organisms are seasonally released in large numbers to reduce pests. Today it is applied on more than 30 million ha worldwide. Europe is the largest commercial market for invertebrate biological control agents, while North America has the largest sales of microbials. A strong growt...
Chapter
Microbes are used in biopesticides and biostimulants. The definition of biopesticides includes microorganisms, and beneficial arthropods; biopesticides are developed for the control of biotic stresses which are caused by pests and diseases. Biostimulants influence the plant’s responses to abiotic stresses. The market for both categories of products...
Conference Paper
ENZICUR is a product registered in the Netherlands in 2007. The registration file was submitted in France in april 2010. It contains two active substances: potassium iodide and potassium thiocyanate. This new natural fungicide has been developed on the basis of the so-called Lactoperoxidase (LP)-system, an anti-microbial system active in bovine mil...
Article
Several regulations apply to the handling and the use of microbial pest control agents. Microorganisms used for control of pests are subject to registration as a “plant protection product”. The history of the development of data requirements for entomopathogens is presented. Current registration requirements are reviewed, particularly for the Europ...
Article
The development of a microbial pest control product requires a structured project plan. The building blocks of the entire process are identified and essential aspects highlighted. The roadmap to successful development and commercialization of a microbial pest control product is amply illustrated in newly designed flow diagrams. Diagrams are present...
Article
Key factors to cost-effective implementation of a microbial pest control product are application strategy, compatibility, and knowledge transfer to the user. This requires the design of a comprehensive integrated pest management programme in which the microbial pest control product is to be incorporated. The first element is an optimal application...
Article
The feasibility of economic mass production of the selected strain and the development of a stable product are key factors to a successful microbial pest control product. Two phases are distinguished, the development of the production process, and the development of the product, including formulation, packaging and field testing. The critical techn...
Article
Commercialization is the final and most difficult step in the development and the introduction to the market of a microbial pest control product. The critical factors that determine success or failure are identified for a company as well as for a product, and recommendations are provided that will facilitate success. The history of the biopesticide...
Article
Microbial pesticides have been developed for a 100 years, but many of these crop protection products have not been successful in the market. The history of microbial pest control products is summarized, the companies involved are reviewed, and the reasons for success and failure are briefly described. The need for a model that facilitates the devel...
Chapter
Quality control can de divided in production control, process control, and product control. The first two refer to internal quality control of the production of a microbial pest control product, and ensure a stable production process with a minimum of failures. Product control refers to the quality of the final product that leaves the factory and w...
Chapter
From a comparison between academic research and industrial research with regard to the finding and the development of a microbial pest control agent, it is concluded that there is a need for well-defined selection criteria and a complete process description for the entire development of a microbial pest control product. This chapter discusses the e...
Article
Mass spectrometry was applied to the identification of the destruxins (dtxs), cyclic peptides that are commonly produced by the fungal insect-pathogen, Metarhizium anisopliae. The aim of the study was to optimise a methodology in order to firstly determine whether these compounds were present in other species and to determine the effect of differin...
Article
Since the appearance of the western flower thrips, Frankliniella occidentalis, in European glasshouses, many attempts have been made to improve the biological methods for thrips control, originally based on the control of Thrips tabaci. Introductions of Neoseiulus (Amblyseius) cucumeris have been increased with respect to both numbers per introduct...
Article
Plant Research International (PRI) in Wageningen deed onderzoek naar endofyten: bacteriën die van nature in planten voorkomen. Enkele bacteriesoorten bleken effectief trips en spint te doden. Een project werd opgezet met als doel de waarde van deze bacteriën te onderzoeken voor de praktijk en er vervolgens biopesticiden van te maken
Article
In dit project worden enkele veelbelovende bacteriestammen gescreend op hun parasitaire werking tegen trips (Frankliniella occidentalis) en spint (Tetranychus urticae). In de loop van het onderzoek zijn verschillende bacterie-isolaten onderzocht en steeds is getoetst of deze isolaten qua werking en veiligheid voldoende perspectief boden als mogelij...
Article
Biological control agents (BCAs) are potential alternatives for the chemical fungicides presently used in agriculture to fight plant diseases. Coniothyrium minitans is an example of a promising fungal BCA. It is a naturally occurring parasite of the fungus Sclerotinia sclerotiorum, a wide-spread pathogen which substantially reduces the yield of man...
Article
Full-text available
The predatory mite Phytoseiulus persimilis is frequently reported to perform poorly on greenhouse tomatoes. As the predators are mass-reared on another host plant (bean), we supposed that they are poorly adapted to tomato, a plant densely packed with poisonous and sticky glandular hairs. This hypothesis was tested by comparing the control capacity...
Chapter
The use of beneficial insects and mites for the biological control of pests has increased significantly in the past thirty years. Bumblebees have been incorporated into protected crop production since the late 1980’s for the pollination of vegetable crops and this stimulates greater use of natural enemies. Also the number of producers of beneficial...

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Projects

Projects (3)
Project
To obtain a much larger area under biological control wordwide by replacing synthetic pesticides with biocontrol agents, and thus, realize healthier food, a cleaner environment and improved instead of impoverished biodiversity.
Project
To develop a set of criteria by which useless or even risky biological control candidates can be quickly identified and dismissed from further research. Improvement of sets of criteria for different types of biological control.