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Willem Peter Bekkering

Willem Peter Bekkering
Princess Máxima Center for Paediatric Oncology · Máxima sports & movement center

PhD, PT

About

34
Publications
3,173
Reads
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476
Citations
Additional affiliations
August 2016 - July 2019
Princess Máxima Center for Paediatric Oncology
Position
  • PostDoc Position
September 2012 - present
Academisch Medisch Centrum Universiteit van Amsterdam
Position
  • Academisch Medisch Centrum
January 2001 - present
Leids Universitair Medisch Centrum
Education
November 2011
Leiden University
Field of study
  • Quality of life, functional ability and physical activity in children and adolescents after lower extremity bone tumour surgery
May 1992
Hogeschool Utrecht
Field of study
  • Paediatric physical therapy

Publications

Publications (34)
Article
Full-text available
The purpose of this study was to translate the English bone tumour DUX (Bt-DUX-Eng) questionnaire for lower extremity bone tumour patients, a disease-specific quality of life (QoL) instrument, into Italian and then examine the validity of the Italian version of Bt-DUX (Bt-DUX-It). The adaptation and translation process included forward translation,...
Article
Full-text available
Background Over the last decades the number of childhood cancer survivors has increased. However, a significant number of childhood cancer survivors suffer from side effects of treatment. This results in a lower quality of life, reduced physical activity (PA), decreased muscle strength and cardiorespiratory fitness compared to healthy peers. To imp...
Article
Question Which is the best strategy to achieve (drug-free) inactive disease in juvenile idiopathic arthritis (JIA)? Methods In a randomised, single-blinded, study in disease-modifying anti-rheumatic drug (DMARD)-naive patients with JIA, three treatment-strategies were compared: (1) sequential DMARD-monotherapy (sulfasalazine or methotrexate (MTX))...
Conference Paper
Full-text available
Background In rheumatoid arthritis treatment, targeted treatment has shown to improve disease outcomes including the option of drug tapering and discontinuation. In non-systemic juvenile idiopathic arthritis (nsJIA) this has not been tried in a trial. Objectives To investigate which of three treatment strategies, targeting at drug-free inactive di...
Article
Full-text available
Background and objectives: In a previous conducted study functional outcome of young patients with bone sarcoma located around the knee was longitudinally evaluated during the first 2 years postoperatively. Functional outcome improved significantly over the first 2 years. The purpose of this descriptive study was to evaluate the functional outcome...
Article
Full-text available
Background Combination therapy with prednisone or etanercept may induce earlier and/or more improvement in disease activity in Disease Modifying Anti Rheumatic Drug (DMARD) naïve non-systemic Juvenile Idiopathic Arthritis (JIA) patients. Here we present three months clinical outcome of initial treatments of the BeSt-for-Kids study. Methods Included...
Article
Full-text available
It remains unclear if quality of life (QoL) improvements could be expected in young patients after malignant bone tumour surgery after 2 years. To assess the course of QoL over time during a long-term follow-up, malignant bone tumour survivors of a previous short-term study were included. Assessments were done at least 5 years after surgery. QoL wa...
Article
Full-text available
Purpose: Shoulder function in children with Neonatal Brachial Plexus Palsy (NBPP) can be impaired. Functional gain is possible by an internal contracture release and muscle tendon transfer (ICL+MTT) for external rotation. This study evaluates the functional results of this intervention. Methods: Assessments were done pre-operatively and 3, 6 and...
Article
Background In the BeSt for Kids (a three-armed treatment strategy study in juvenile idiopathic arthritis (JIA)) time to inactive disease, time to flare after Disease Modifying Anti Rheumatic Drug (DMARD) discontinuation, ACRpedi scores, functional ability, safety, and radiological damage are compared. Follow up will be 2 years. Here we present the...
Article
Purpose: To translate the Dutch DUX questionnaire for lower extremity bone tumor patients (Bt-DUX), a disease-specific quality of life (QoL) instrument, into the English (UK) language and preliminary validate the English version in patients who were treated for lower-extremity bone tumors. Methods: Adaptation and translation process included for...
Article
Few longitudinal data are available concerning quality of life (QoL) and functioning of young patients undergoing surgical procedures for malignant bone tumors around the knee joint. Aim of the present study was to evaluate patients' quality of life, functional ability, and physical activity during a 2-year postoperative period. This prospective st...
Article
To systematically review published studies comparing Quality of Life (QoL), functional ability and/or physical activity between different surgical interventions due to a malignant bone tumour of the leg. A systematic literature search, covering the years 2000-2010 was performed using the PubMed, Embase, Web of science and Cochrane databases. Studie...
Article
Aim of our study was to compare functional ability and physical activity in children and young adults who underwent surgery for a malignant bone tumor that was located around the knee. This cross-sectional study included 82 patients aged 8-25 years with a follow-up of 1-5 years. The functional ability and the amount of physical activity were evalua...
Article
This study aimed to compare the health related quality of life (HRQoL) of children and adolescents after malignant bone tumor surgery of the leg with healthy controls. Patients between 8 and 25 years old were cross-sectional recruited. Patients under 16 years of age received the TNO (Netherlands Organization for Applied Scientific Research) and AZL...
Article
Full-text available
The Childhood Health Assessment Questionnaire (CHAQ30) is the most commonly used physical functioning questionnaire for children with Juvenile Idiopathic Arthritis (JIA). By revising the CHAQ30 Lam et al. succeeded in decreasing the ceiling effect of this questionnaire in a North American population of children with diverse musculoskeletal diseases...
Article
To examine the practical applicability, internal consistency, and validity of the Bt-DUX, a disease-specific Health Related Quality of Life (HRQoL) instrument. The Bt-Dux was developed to examine patients' individual values of their life after a malignant bone tumor of the lower extremity at four domains (cosmetic, social, emotional, and functional...
Article
Full-text available
Background Adding 8 more demanding items to the original Childhood Health Assessment Questionnaire(CHAQ) lowers the ceiling effect of this questionnaire [1]. In this cross sectional study the score distribution of two categorical response options of the revised CHAQ was explored. Materials and methods Five Dutch tertiary centres for paediatric rheu...
Conference Paper
Full-text available
Development of a video information program for children before lower limb amputation or rotationplasty. Willem P Bekkering1), Eva B. Toele2), Lilian MM v/d Meer2), Frans JW Smiers2), Antonie HM Taminiau3). Departments of Physical Therapy1), Pediatrics2) and Orthopedics3) of the Leiden University Medical Center, The Netherlands. Purpose : There is...
Article
Full-text available
We compared the measurement properties of a performance test (Juvenile Arthritis Functional Assessment Scale; JAFAS) with a questionnaire-based instrument (Childhood Health Assessment Questionnaire; CHAQ) to measure functional ability in patients with juvenile idiopathic arthritis on the level of individual items. In 28 consecutive children visitin...
Article
To assess the safety and efficacy of intensive immunosuppression followed by T cell-depleted autologous hematopoietic stem cell transplantation (ASCT) for induction of disease remission in children with refractory progressive juvenile idiopathic arthritis (JIA). Twenty-two patients with progressive refractory JIA were followed up over a median peri...
Conference Paper
Full-text available
The value of the DUX-BT as a subjective measure of health related quality of life in patients who underwent surgery for a lower extremity malignant bone tumour Willem P Bekkering1), Theodora P.M. Vliet Vlieland 1), Jacob K. Anninga 2),H.M. Koopman 2), Gerard.R. Schaap 3), Auke. Beishuizen 4), Antonie HM Taminiau 5). Departments of Physical Therapy...
Chapter
Juveniele dermatomyositis (jdm) is een auto-immuunaandoening die gepaard gaat met ontstekingen van de kleine bloedvaatjes (vasculitis). Primair zijn spieren en huid aangedaan, maar het ziekteproces kan zich ook in andere organen manifesteren.
Article
In rheumatic diseases the use of corticosteroids (CS), immobility, or the disease itself, may cause osteoporosis and growth retardation. We evaluated bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA), growth and physical activity in 27 children with rheumatic disease, all treated with high dose CS for at least one year, in a cros...
Article
Full-text available
Knowledge about the impact of joint impairment on functional ability is needed in planning care and setting treatment goals in children with juvenile idiopathic arthritis (JIA). We investigated the relationship between joint impairments and upper and lower limb function. Twenty-one children with systemic JIA with an average age of 9.2 years and a m...
Article
Full-text available
Pearson's correlation coeYcients (r) ranging from 0.48 to 0.92 (n=18) and from 0.63 to 0.88 (n=13), respectively, p<0.05). Patients with JA had lower levels of physical wellbeing (mean physical score (PhS) 41.7 v 56.0, p<0.001) and emotional and social wellbeing (mean psychosocial summary score (PsS) 50.4 v 55.7, p<0.001) than controls. At base-lin...

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