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I am a PhD student studying transcriptional regulation in plants under the mentorship of Dr. Carol Huang and Dr. Gloria Coruzzi in the NYU GSAS Biology program. I previously conducted research under the mentorship of Dr. Judy Brusslan at CSULB. With funding from NIH RISE, I studied leaf senescence in Arabidopsis thaliana. I also interned with Dr. Alison DeLong at Brown University to study how protein phosphatases regulate Arabidopsis plant size.
August 2019 - December 2019
- Students enrolled in this and met with me in a classroom setting twice a week to work on class material. I created an interactive learning environment to promote collaborative learning that empowered students to develop life-long study skills.
June 2019 - August 2019
Leadership Alliance Summer Internship at Brown University
- I interned in Dr. Alison DeLongs Plant Biology lab. I studied the affect that a particular protein phosphatase has on plant growth. I learned how to grow plants in sterile media and expose them to varying doses of pharmacological treatments. I learned how to stain and visualize different cell types under a microscope. I learned how to measure certain plant tissues using ImageJ. I also interrogated online datasets for publicly available gene expression data.
January 2019 - December 2019
Nutrient remobilization during leaf senescence nourishes the growing plant. Understanding the regulation of this process is essential for reducing our dependence on nitrogen fertilizers and increasing agricultural sustainability. Our laboratory is interested in chromatin changes that accompany the transition to leaf senescence. Previously, darker g...
In plants, the vegetative to reproductive phase transition (termed bolting in Arabidopsis) generally precedes age-dependent leaf senescence (LS). Many studies describe a temporal link between bolting time and LS, as plants that bolt early, senesce early, and plants that bolt late, senesce late. The molecular mechanisms underlying this relationship...
Statement of contributions to field: While it is widely accepted that early bolting generally confers early leaf senescence, the molecular basis of this temporal relationship has not been explored. Arabidopsis shows leaf senescence related gene expression changes in older rosette leaves associated with the transition to bolting at the shoot apical...
Nutrient remobilization during leaf senescence nourishes the growing plant. Understanding the regulation of this process is essential for reducing our dependence on nitrogen fertilizers and increasing agricultural sustainability. Our lab is interested in chromatin changes that accompany the transition to leaf senescence. Previously, darker green le...
In plants, the vegetative to reproductive growth phase transition (bolting) precedes age-dependent leaf senescence (LS). During LS, nitrogen and other macromolecules are recycled from dying leaves and relocated to reproductive organs (fruits/seeds), which in many species are then harvested for human consumption. Many studies describe a temporal link between bolting time and LS, as plants that bolt early, senescence early, and plants that bolt late, senesce late. Understanding the timing of bolting and its molecular connection to LS is agriculturally important, as understanding the molecular causes of coupling may allow for the development of crops that can overcome stress-related early LS caused by early bolting. Homozygous Arabidopsis trithorax (ATX) triple T-DNA insertion mutants (atx1 atx3 atx4) display significantly early bolting coupled to significantly early LS, thus we used this line as a model to study the coupling of these developmental stages. We completed an RNA-seq time-course experiment that revealed 121 genes with differential expression (DEGs) in early bolting atx triple mutants relative to vegetative wildtype plants of the same age. We hypothesize that some of these DEGs, which change expression during bolting, are signaling the onset of LS. If a gene is responsible for coupling, then a plant carrying a null mutant copy of that gene should display an uncoupled phenotype. Twenty genes from this list contain predicted regulatory domains, likely having a role in some type of signaling. To test our hypothesis, T-DNA insertion mutants for 17 of the 20 potential regulatory genes were isolated to screen for mutations that uncouple bolting and LS. Preliminary data from the candidate screen show four mutants that display uncoupled bolting and LS phenotypes. Currently, data support the hypothesis that there are bolting-time specific expression changes of senescence-regulating genes. Further study of the four regulatory gene candidate mutants may elucidate the molecular connection between bolting and age-dependent leaf senescence.