Widya Dwi Aryati

• University of Indonesia

The search for new antibiotics against drug-resistant microbes has been expanded to marine bacteria. Marine bacteria have been proven to be a prolific source of a myriad of novel compounds with potential biological activities. Therefore, this review highlights novel and bioactive compounds from marine bacteria reported during the period of January...

Objective: New psychoactive substances (NPS) have been rapidly developed to avoid legal entanglement. In 2013–2018, the number of cathinonederivedcompounds increased from 30 to 89. In 2016, of 56 NPS compounds, 21 were identified as cannabinoid-derived; only 43 were regulated inthe narcotics law. Artificial intelligence, such as machine and deep le...

Adenosine is a neuromodulator that regulates the body's response to dopamine and another neurotransmitter in the brain that is responsible for motoric, emotion, learning, and memory function. Adenosine is a G-protein-coupled receptor and has four subtypes, which are A 1, A 2A , A 2B , and A 3. Adenosine A 2A is located in the striatum of the brain....

Objective: Human immunodeficiency virus (HIV-1) is a virus that causes acquired immunodeficiency syndrome, a disease considered to be one of themost dangerous because of its high mortality, morbidity, and infectivity. The emergence of mutant HIV strains has led treatment to target proteaseas reverse transcriptase and integrase enzyme become less ef...