Wenli Sun

Chinese Academy of Agricultural Sciences | CAAS · Institute of Biotechnology (IB)

Natural products have a broad range of diversity of multidimensional chemical formation which play an important role, and indicate the crucial nature as a golden source for gaining herbal drug discovery. Thymoquinone performs various functions and has anticancer, anti-inflammatory, antioxidant, and anti-diabetic, impacts. It shows the significant i...

Natural products have been considered a potential resource for the development of novel therapeutic agents, since time immemorial. It is an opportunity to discover cost-effective and safe drugs at the earliest, with the goal to hit specific targets in the HIV life cycle. Natural products with inhibitory activity against human immunodeficiency virus...

Traditional Iranian medicine is usually used for both prevention and relief of cold and flu symptoms in China, Iran, and many other Asian countries all over the world. There are 4 kinds of influenza viruses. Unlike type B, which may cause seasonal epidemics, type A viruses can cause pandemics, and influenza C may lead to mild human infection with l...

In addition to the economic losses because of insect pests, a significant part of insect pests can instantly lead to the deterioration and mildew of agricultural products, which all have great hidden hazards to human health. In view of insect pests, the principle means of control and prevention in China is spraying chemical agents. Nevertheless, sp...

Traditional Chinese medicines (TCM) have been considered an important source of curative remedy for many years due to their potential chemical components which can promote health and prevent diseases. According to TCM, influenza is differentiated into two kinds, namely, wind-cold syndrome and wind-heat syndrome. Many traditional Chinese medicinal p...

Traditionally, Middle Eastern herbal medicines, especially traditional Iranian medicines (TIM), have been used by cancer patients both during and after active cancer treatments. Medicinal plants and herbs which are common in traditional Iranian medicine are considered to be less toxic and less expensive than chemical drugs. Alkaloid anti-cancer com...

Traditional the Middle Eastern herbal medicines, especially traditional Iranian medicines (TIM) always used by cancer patients both during and after active cancer treatments. Medicinal plants and herbs which are common in traditional Iranian medicine considered to be less toxic, and less expensive than chemical drugs. Alkaloid anti-cancer compounds...

Peganum harmala is a perennial herbaceous, glabrous plant mainly found in North Africa, the Middle East, and Central Asia. Its seeds showed that alkaloids belonging to the β-carboline family such as harmaline, harmine, harman, harmalol, and harmol which are responsible for a wide range of pharmacological impacts. The main components from its seeds...

Traditional Chinese medicines (TCM) have been considered as an important source of curative remedy for many years, due to their potential chemical components which can promote health and prevent diseases. According to TCM, influenza is differentiated into 2 kinds, namely, wind-cold syndrome and wind-heat syndrome. Many traditional Chinese medicinal...

Leek is one the main vegetable which can promote good health and serves as a primary defense mechanism against different diseases. Leek (Allium ampeloprasum) is a robust, winter-hardy biennial plant which does not form a hard bulb like garlic or onion, and they are grown for their thick and long white stem. One of the most important herbal food whi...

One of the most tea catechin in epigallocatechin gallate. It is the principle plentiful tea 9 polyphenol, accompained by other polyphenols such as epigallocatechin, epicatechin-3-gallate, epi-10 catechin, and catechin. The principle notable pharmacological characteristics of Epigallocatechin 11 gallate are HIV infection, antineoplastic, hypertensio...

Pomegranate is native to Mediterranean regions and Iran which have been extensively used in different cultures and countries. Nutrient components of pomegranate peel is moisture, total solid, protein, total sugars, reducing sugars, fat contents, ash, and crude fiber. Fatty acids identified in pomegranate seed are punicic acid, caproic acid, myristi...

Basil (Ocimum basilicum L.) is one of the most important member of Ocimum genus. The dominant volatile components of basil are eugenol, methyl chavicol, linalool, methyl cinnamate and bergamotene. It is an important part cuisines in countries like Iran, China and India. The main phe-nolic components of basil are phenolic acids and flavonol-glycosid...

Biostimulant application can be considered an effective, practical, and sustainable nutritional crop supplementation and may lessen the environmental problems related to excessive fertilization. Biostimulants provide beneficial properties to plants by increasing plant metabolism, which promotes crop yield and improves the quality of crops; protecti...

The most abundant protein found in mammals is collagen, and there are around 28 different types of collagen found in the human body, but there are five types, namely, Type I, Type II, Type III, Type V, and Type X, most generally applied in supplements, and the five common types of collagen are available in various forms and form different sources,...

Introduction: Traditional Chinese medicine is an ancient system of wellness and health that has been used in almost all countries of the world, specially in Asia for thousands of years. Method: The growth, development, final yield and chemical compounds of medicinal plants can be negatively influenced by different kinds of biotic and abiotic stres...

Fermentation is being utilized since ages as a safe process for food preservation. Fermentation in winemaking is the process which converts grapes juice into wine. Alcoholic fermentation is the principle for the manufacturing of alcoholic beverages like wine and beer. Several by-products are produced by the alcoholic fermentation of organic carbon...

Medicinal and aromatic plants are gaining more importance because of their potential application in food, pharmaceutical and fragrance industry. Medicinal and aromatic plants have been used in cosmetics, perfumery, pharmaceuticals and food flavoring since ancient times, because of the presence of essential oils and different components. Seeds are o...

Knowledge about the pharmacological benefits of different seeds is an important factor for the cultivation and application of medicinal herbs and plants. The seeds of medicinal plants are stores of valuable and active secondary metabolites that have been commercially and economically beneficial and helpful for medicine and pharmacy. The major param...

Chitosan is illustrated in research as a stimulant of plant tolerance and resistance that promotes natural defense mechanisms against biotic and abiotic stressors, and its use may lessen the amount of agrochemicals utilized in agriculture. Recent literature reports indicate the high efficacy of soil or foliar usage of chitin and chitosan in the pro...

Background: Turmeric (Curcuma longa L.), belonging to the Zingiberaceae family, is a perennial rhizomatous plant of tropical and subtropical regions. The three major chemical components responsible for the biological activities of turmeric are curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Method: The literature search included review ar...

Knowledge about pharmacological benefits of different seeds is an important factor for cultivation and application of medicinal herbs and plants. The seeds of medicinal plants are stores of valuable and active secondary metabolites that have been commercially and economically beneficial and helpful for medicine and pharmacy. The major parameter of...

Cholesterol was first found in gallstones as an animal sterol; hence it is called cholesterol. Cholesterol oxidase is the chief enzyme in the process of cholesterol degradation. Its role is obtained by the coenzyme FAD, which catalyzes the isomerization and oxidation of cholesterol to produce cholesteric 4-ene-3-ketone and hydrogen peroxide at the...

Background Polymerase chain reaction is an approach to make numerous copies of specific DNA. PCR has been applied for the investigation of infectious sicknesses caused by viral, protozoan, bacterial, fungal, or other infectious factors. Objective This review manuscript aims to survey the usage of PCR, LAMP, RPA, and RAA in rapid detection and high...

Biostimulants are one of the most important substancesfor improving productivity, growth and yield of plants as well as heavy metal detoxification, and stimulating natural toxins, controlling pests and diseases and boosting both water and nutrient efficiency. Google Scholar, Science Direct, CAB Direct, Springer Link, Scopus, Web of Science, Taylor...

Multi-omics approaches have developed as a profitable technique for plant systems, a popular method in medical and biological sciences underlining the necessity to outline new inte-grative technology and functions to facilitate the multi-scale depiction of biological systems. Understanding a biological system through various omics layers reveals su...

Background Natural herbal medicines may contribute to prevent and treat various diseases, and they have substantial medicinal properties. Objective The goal of this manuscript is to survey natural benefits, chemical components, and medicinal values of pennyroyal. Methods The goal of this manuscript was to outline the most notable advantages and p...

Traditional medicines are considered as both food items and medicine which have been used a history of thousands years. They have contained active ingredients aerial, underground parts of plants and they contain variety of pharmacological active plant constituents. The aim of this study was to summarize and highlight the most important traditional...

Wine production is the result of the interaction between various strains and grapes, and its good quality is also affected by many factors. Aureobasidium, Cladosporium, Candida, Filobasidium, Hanseniaspora, Hannaella, Saccharomyces, Wickerhamomyce, Alternaria, Starmerella, Acetobacter, Papiliotrema, Bradyrhizobium, Leuconostoclia, Gluconobacter, Co...

Background Longan (Dimocarpus longan Lour.) is a characteristic Sapindaceae fruit native to China and is a seasonal non-climacteric fruit with unique flavor, rich nutrients, and high economic value. Longan was used as a traditional Chinese medicine for various purposes, such as soothing nerves, relieving insomnia and increasing blood metabolism. Lo...

Background In this mini-review article, two important dairies which can be considered as functional foods from west and center of Asia, particularly Iran, have been discussed. Doogh and kashkh are considered as national drinks in Iran, and have tremendous health benefits. Objective The goal of this manuscript is to survey the principal roles of Do...

Background Medicinal plants have become the focus of intense researches through the identification and determination of their pharmacological benefits with their different chemical constituents. Objective The aim of this mini-review is to highlight the most important health benefits of Syrian bean caper and parsnip. Methods The manuscript consist...

Phenolic compounds and flavonoids are potential substitutes for bioactive agents in pharmaceutical and medicinal sections to promote human health and prevent and cure different diseases. The most common flavonoids found in nature are anthocyanins, flavones, flavanones, flavo-nols, flavanonols, isoflavones, and other sub-classes. The impacts of plan...

Sustainable farming of horticultural plants has been the focus of research during the last decade, paying significant attention to alarming weather extremities and climate change, as well as the pressure of biotic stressors on crops. Microbial biostimulants, including plant growth-promoting bacteria (PGPB) and arbuscular mycorrhizal fungi (AMF), ha...

Background Plants have played an essential role in the search for new compounds for the most diverse therapeutic purposes. Recently, more attention is paid to natural antioxidants because of the possible insecurity of synthetic antioxidants Objective The review is aimed at summarizing the most important and common natural antioxidants and their re...

The review aims to summarize the major and dominant natural antioxidants and their resources from medicinal and herbal plants with antiviral, anti-inflammation and antimicrobial activities. For this review manuscript, online databases, including Web of Science, Scopus, PubMed, and Science Direct, were searched for papers published from 1960 to Nove...

Background Virus is a tiny agent, around one-hundredth the size of a bacterium which can infect cells of plants and animals. Seven coronaviruses are known to infect humans, three of them are serious, namely, SARS (severe acute respiratory syndrome, China, 2002), MERS (Middle East respiratory syndrome, Saudi Arabia, 2012), and SARS-CoV-2 (COVID-19)...

The world needs a paradigm change from the current views on many plants to secure both future food and nutrition. Many neglected and underutilized plants, specially medicinal and aromatic plants, are nutrient dense, appropriate in diversifying diets, provide enough vitamins and micronutrients for people, high resistant to diseases and pests, and ca...

Fermentation has been used for ages as a safe technique for food preservation, and it uses minimal resources. Fermentation is related to a wide range of catabolic biochemical procedures in both eukaryotes and prokaryotes. Yeasts are eukaryotes; they can use oxygen while also having the ability to live without oxygen. The lactate fermentation proces...

Background The review aims to summarize the most important and common natural antioxidants and their resources from medicinal plants, as the vast majority in the world have always applied medicinal plants for the prevention and treatment of various diseases. Keywords were searched in PubMed/MEDLINE, Scopus, and the Institute for Scientific Informat...

Introduction Biostimulants consist of natural ingredients, metabolites of fermentation, micro-organisms, algae or plant extracts, bacteria, mushrooms, humus substances, amino acids, biomolecules, etc. Methods In this study, all relevant English-language articles were collected. The literature was reviewed using the keywords of biostimulant, medici...

Asian scholars especially from Iran and China preserved most of the wisdom and knowledge of antiquity in their writing and they had great influence even on both European traditional and modern medical sciences. The current searching was done by the keywords in main indexing systems including PubMed/MEDLINE, Scopus and Institute for Scientific Infor...

The ability of adaptation of Rhizobia in diverse environment namely, soil, rhizosphere and grown within legume roots may lead to nitrogen fixation, in a complicated process which contain a coordinated exchange of signal between plants and the symbionts. Green manures, cash and cover crops have significant role in soil fertility. Green manuring tech...

Asparagus (Asparagus officinalis L.), belonging to the Asparagaceae family and has substantial medicinal properties. The name for asparagus comes from the Greek meaning sprout or shoot. This review aims to summarize the most important traditional and modern health benefits and pharmaceutical advantages of asparagus. This manuscript included randomi...

Different compounds with bioactive constitutents can be applied as biostimulants to increase plant growth and development under both normal and stressful conditions. Biostimulants utilization can be considered as a sustainable and beneficial nutritional crop management, and may decrease the negative impacts associated with excessive chemical fertil...

The aim of this review was to summarize the most important traditional medinical herbs and plants that are being used in different parts of the world with a focus on a green anti-cancer approach. The most important impacts of medicinal plants on cancer treatments are prevention of cancer occurrence, decreased side effects, ameliorated post-operativ...

Nutrition therapy on the basis of traditional medicinal plants and herbs is common in many Asian countries, especially Iran and China. Rheum species, especially rhubarbs, belong to plant medicines recognized in 2500 BC. An online search of the literature was carried out at Pub-med/Medline, Scopus, and Google scholar, covering all years until April...

The review is aimed at summarizing the most important and common natural antioxidants and their resources from traditional Iraniand Chinese medicinal sciences. The most important medicinal plants with antioxidant activities in Iran are Artemisia, berberry fruit, borage, calendula, coriander, cumin, green tea, hawthorn, jujube, pomegranate, rose, ro...

Biostimulants which contain substances or products including natural compounds, special formulation and microorganisms have gained a considerable attention as sustainable method for heavy metal detoxification, stimulate natural toxins, controlling diseases and pests, may increase both water and nutrient efficiency. Biostimulants are important produ...

Different isothermal amplification methods are the signal amplification assays, the probe amplification assays, and the target amplification assays. Molecular techniques used for recognition of quinolone resistance consist of the use of various techniques such as polymerase chain reaction fragment length polymorphism, PCR, single-strand conformatio...

Background Medicinal plants and natural feed additives are the most important alternatives in animal production, especially broiler production, due to the ban on the use of certain antibiotics, their cost-effectiveness and harmful residual effects. Objective In this mini-review article, some important medicinal herbs and plants with positive effec...

Sumac is the wine-colored ground spice, belonging to the cashew family (Anacardiaceae). The most important components of sumac ethanolic extract obtained from sumac are Trans-Caryophyllene, diethyl ester, Butanedioic acid, Cembrene, 1,7-Nonadien-4-ol,4,8-dimethyl, Malate, Palmitate, 9-Octadecenoic acid, Ethyl Linoleic acid, Phytol and Ethyl Linolea...

Background The most important advantages of foliar fertilization are to improve plant growth and crop quality, appropriately manage the nutritional status of plants, enhance disease resistance and regulate nutrient deficiencies. Main body The aim of this manuscript is to outline and emphasize the importance of foliar application of nutrients in or...

In this mini-review article, we have mentioned the key roles of some of the most important herbal plants medicines containing flavonoids and phytochemicals with antiviral activities. All relevant information was searched for terms of influenza, phytochemicals, SARS, SARS-Cov-2, flavonoids, and traditional medicinal plants uses from reliable databas...

Background Ginkgo (Ginkgo biloba) is a living fossil and a deciduous tree, which has extracts with antidiabetic, antioxidant anticancer, antihypertensive, immunestimulative, hepato-protective and antimicrobial activities, memory enhancement efficiency and beneficial effects against neurodegenerative disease. Objective The goal of this manuscript i...

Medicinal plants, particularly edible plants have long been used as traditional knowledge to treat and prevent obesity, especially in Asian countries, because various bioactive compounds from both herbs and fruits have been found useful for anti-obesity drug discovery and development processes. Obesity is an important problem for normal growth in c...

Ajwain oil contributed to a wide range of medicinal applications, such as antibacterial, antifungal, anti-inflammatory, antioxidant, antibacterial, cytotoxic, anti-lithiasis, nematicidal, anthelmintic, and antifilarial activities. The seeds can be used as stimulant, sialagogue, stomachic, carminative, aromatic, antiseptic, antihypertensive, antispa...

The functional food industry has been developing rapidly in recent years. Great progress has been made in this industry, especially in the number the claims related and the quality of the functional foods. The most important pharmacological properties of jujube are antidiabetic effects, hypnotic-sedative and anxiolytic effects, neuroprotective acti...

Sumac is a small tree or shrub with thick branches and smooth gray bark. It has large, deciduous, compound leaves with 11–31 hairless sawtooth leaflets. Dense cone-shaped clusters of whitish male and female flowers grown on separate plants. The fruits are dark red fuzzy berries in similar dense clusters. The most important medicinal properties of t...

The increasing importance of organic food production is due to better environmental performance than conventional farming. Organic farming is a system that aligns well with sustainability. In many countries, especially developed countries, functional foods are considered to be and are ranked as one of the critical state policies, since adequate nut...

Pulses make up a major share of the human diet in many regions of the world and play a significant role in human nutrition as a source of protein, vitamins, minerals, dietary fiber, and folic acid. Grain pulses also contain certain biologically active components, including enzyme inhibitors, lectins, phytates, oligosaccharides, and phenolic compoun...

The adzuki bean (Vigna angularis) is a traditional legume crop that plays a crucial role in both the sustainability of agricultural systems and the supply of food protein. Having been used for thousands of years in China as traditional Chinese medicine and food, the adzuki bean has a great potential to be a drug candidate or functional food. Adzuki...

Legumes in traditional medicine play a key role in the world. In majority of countries, especially in Iran and China, western and traditional medicine has been practiced side by side of each other. The aim of this study is to review bioactive components and chemical constituents of some important legumes in East of Asia. All relevant papers in Engl...

Asian scholars especially from Iran preserved most of the wisdom and knowledge of antiquity in their writing and they had great influence even on both European traditional and modern medical sciences. Avicenna famous book was Canon, which reviewed all medical knowledge studied by the ancient Greek and Muslim scientists. Avicenna has introduced many...

Fenugreek (Trigonella foenum-graecum L.) belongs to the botanical family Papilionaceae, and its native geographic range is the area extending from Iran to Northern India, but it is presently cultivated also in other regions of the world. Historically, fenugreek has been used as an important traditional, multipurpose medicinal herb in Iranian, India...

Traditional medicinal plants contain various ranges of chemical contents and they have become popular because of effectiveness, frequently inadequate provision of modern medicine, preferences and cultural beliefs. Pomegranate belongs to the family of Punicaceae, and its various pharmacological activities are due to presence of wide range of bioacti...

Chlorophyll is a green photosynthetic pigment, and photosynthesis drives the global carbon cycle. The reduction of protochlorophyllide (Pchlide) to chlorophyllide (Chlide) in the penultimate stage of biosynthesis of chlorophyll (Chl) is catalyzed by light-independent protochlorophyllide reducatse (DPOR), and the light-dependent protochlorophyllide...

Rhizobia which are soil bacteria capable of symbiosis with legume plants in the root or stem nodules and perform nitrogen fixation. Rhizobial genera include Agrobacterium, Allorhizobium, Aminobacter, Azorhizobium, Bradyrhizobium, Devosia, Mesorhizobium, Methylobacterium, Microvirga, Ochrobacterum, Phyllobacterium, Rhizobium, Shinella and Ensifer (S...

Overweight and obesity have become global epidemics, especially during the lockdown due to the COVID-19 pandemic. The potential of medicinal plants as a better and safe option in treating obesity and overweight has gained attention in recent years. Obesity and overweight has become a major public health concern, and its incidence rising at an alarm...

Background Caper ( Capparis spinosa L.) is a common member of the genus Capparis , which is a perennial shrub and thorny, and a common aromatic plant in many parts of the world, especially the Mediterranean regions. Main body The aim of this mini-review was to outline the most significant health benefits of caper in both traditional and modern pha...

Herbs are natural products and herbal medicine has become a popular form of healthcare. Herbal-derived remedies may increase pharmacological qualities and improve prevention and treatment of several diseases. In this study, all relevant articles in English language were collected. Keywords of milk thistle, myrrh, mint and natural products were sear...