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Introduction
Additional affiliations
January 1999 - present
Position
- Head of the cochlear implant team (adults), research, patient selection
Publications
Publications (70)
Objective:
This study aimed to evaluate long-term cochlear implant (CI) outcomes in individuals with mono-allelic pathogenic variants in WFS1, which is associated with both Wolfram-like syndrome and DFNA6/14/38.
Design:
Retrospective case series.
Study sample:
Seven CI recipients, ranging from eight months to 58 years of age, were included in...
Introduction
Various factors, including an aging population and expanding eligibility criteria, may increase the demand for cochlear implants (CIs), potentially resulting in longer waiting times. In most Dutch CI centers, the time between referral and surgery exceeds 6 months. Clinical experience suggests that during the waiting period for cochlear...
Purpose
This study assessed whether the Fazekas score could account for the variability in cochlear implantation (CI) outcomes among individuals with DFNA9 and evaluated signal loss in the semicircular canals (SCCs) on magnetic resonance imaging (MRI) among individuals with DFNA9.
Method
This retrospective cross-sectional study included CI recipie...
Objectives
Usher syndrome (USH), characterized by bilateral sensorineural hearing loss (SNHL) and retinitis pigmentosa (RP), prompts increased reliance on hearing due to progressive visual deterioration. It can be categorized into three subtypes: USH type 1 (USH1), characterized by severe to profound congenital SNHL, childhood-onset RP, and vestibu...
Background
The role of patients in healthcare research is slowly evolving, although patient roles in the research process are limited. This paper reports on a patient‐led research project aiming to develop a musical hearing training programme for patients with a cochlear implant (CI): the Musi‐CI programme. A CI is an inner ear prosthesis that allo...
Background: Traditional speech recognition testing in Cochlear Implant (CI) care primarily captures aggregate speech recognition performance, often overlooking detailed phoneme identification errors. This feasibility study introduces a fitting approach focusing on individual CI users' phoneme difficulties identified through self-testing paradigms.M...
Purpose: Current clinical measures used in cochlear implantation (CI) provide a broader view of speech recognition ability at word-level, often missing granular details contained at phoneme-level that may be valuable for CI mapping. This study evaluates how outcomes of Phoneme Recognition in Quiet tests (PRQ) differ from those of more commonly used...
Background
The spiral ganglion hypothesis suggests that pathogenic variants in genes preferentially expressed in the spiral ganglion nerves (SGN), may lead to poor cochlear implant (CI) performance. It was long thought that TMPRSS3 was particularly expressed in the SGNs. However, this is not in line with recent reviews evaluating CI performance in...
Purpose
This study describes a protocol for a novel individualized phoneme training program for adult cochlear implant (CI) users, based on individual phoneme confusion errors. The protocol is underpinned by a literature review on phoneme training and a focus group with adult CI users.
Method
After a literature search, five studies were included f...
Objective:
The variability in outcomes among adult cochlear implant (CI) users poses challenges for clinicians in accurately predicting the benefits of the implant for individual candidates. This study aimed to investigate the accuracy and confidence of clinicians in predicting speech perception outcomes for adult CI users one-year post-implantati...
A cochlear implant (CI) is a prosthesis that allows people with severe to profound hearing loss to understand speech in quiet settings. However, listening to music presents a challenge to most CI users; they often do not enjoy music or avoid it altogether. The Musi-CI training course was developed for CI users with the goal of reducing music aversi...
Purpose
Programming a cochlear implant (fitting) is an essential part of a user’s post-implantation journey, defining how sound will be translated into electrical stimulation and aiming to provide optimal speech perception outcomes. Currently, there are no established, evidence-based guidelines for fitting cochlear implant users, leading to a high...
Objectives:
The stability of remote testing in cochlear implant care was studied by testing the influence of time-of-day, listener fatigue, and motivation on the outcomes of the aided threshold test (ATT) and digit triplets test (DTT) in cochlear implant (CI) recipients using self-tests at-home on a smartphone or tablet.
Design:
A single-center...
Objectives: The stability of remote testing in cochlear implant care was studied by testing the influence of time-of-day, listener fatigue, and motivation on the outcomes of the aided threshold test (ATT) and digit triplets test (DTT) in cochlear implant (CI) recipients using self-tests at-home on a smartphone or tablet. Design: A single-center rep...
Objectives:
Current surgical techniques aim to preserve intracochlear structures during cochlear implant (CI) insertion to maintain residual cochlear function. The optimal technique to minimize damage, however, is still under debate. The aim of this study is to histologically compare insertional trauma and intracochlear tissue formation in humans...
Introduction
Cochlear implantation (CI) is a (cost-)effective intervention for people with severe or profound hearing loss. Since its introduction experience increased and the technology evolved, leading to better results and relaxation of CI eligibility criteria. Meanwhile, with national healthcare costs increasing there is a need for evidence of...
Background
Cochlear implants (CIs) are considered an effective treatment for severe-to-profound sensorineural hearing loss. However, speech perception outcomes are highly variable among adult CI recipients. Top-down neurocognitive factors have been hypothesized to contribute to this variation that is currently only partly explained by biological an...
Objectives. The stability of remote testing in cochlear implant care was studied by testing the influence of time-of-day, listener fatigue, and motivation on the outcomes of the aided threshold test (ATT) and digit triplets test (DTT) in CI recipients using self-tests at-home on a smartphone or tablet.Design. A single-center repeated measures cohor...
Introduction
When Cochlear implants (CI) were first introduced, only postlingually, profoundly hearing impaired individuals were implanted unilaterally. As experience grew, eligibility was followed by prelingual deaf children, and a second contralateral CI was being considered. Due to surgical and technological improvements, eligibility criteria fo...
Objectives:
Eligibility criteria for cochlear implantation (CI) are shifting due to technological and surgical improvements. The aim of this study was to explore the impact of further expanding unilateral CI criteria in those with severe hearing loss (HL) (61-80 dBHL) in terms of number of CI recipients, costs, quality of life, and cost-effectiven...
Purpose
The aim of this study was to evaluate the intracochlear position of the Slim Modiolar Electrode (SME) after insertion via the extended Round Window (eRW) approach, and to correlate this with residual hearing preservation and speech perception outcomes.
Methods
Twenty-three adult participants, consecutively implanted with the SME via the eR...
Background Histopathologic studies reported that cochlear implantation, a well-established means to treat severe-to-profound sensorineural hearing loss, may induce inflammation, fibrosis, and new bone formation (NBF) with possible impact on loss of residual hearing and hearing outcome. Purpose To assess NBF in vivo after cochlear implantation with...
Purpose
This scoping review examines the available evidence on the effect of unilateral cochlear implantation (CI) in adults with postlingual bilateral hearing loss on societal-related outcomes in terms of work, autonomy and participation.
Methods
Five databases were searched (Pubmed, Web of Science, Embase, PsycINFO and Cochrane Library). Publica...
Objective:
The aim of this study was to compare Transimpedance Matrix (TIM-) measurement and X-ray fluoroscopy for the intraoperative detection of electrode array tip fold-over in cochlear implant recipients.
Study design:
Retrospective agreement study.
Setting:
Tertiary referral hospital.
Patients:
Forty-two patients (47 ears) consecutively...
The global digital transformation enables computational audiology for advanced clinical applications that can reduce the global burden of hearing loss. In this article, we describe emerging hearing-related artificial intelligence applications and argue for their potential to improve access, precision, and efficiency of hearing health care services....
Objectives:
The primary objective of this study is to identify the biographic, audiologic, and electrode position factors that influence speech perception performance in adult cochlear implant (CI) recipients implanted with a device from a single manufacturer. The secondary objective is to investigate the independent association of the type of ele...
Purpose
Some cochlear implant (CI) patients lose their residual hearing during surgery. Two factors that might play a role in residual hearing loss are the change in intracochlear hydraulic pressure and force on the cochlear wall during electrode insertion. The aim of this study is to investigate whether a difference in peak hydraulic pressure and...
Objectives:
The aim of this study is to report on our preliminary experience with Transimpedance Matrix (TIM)-measurement for the detection of cochlear implant electrode tip foldovers compared with intraoperative imaging in patients implanted with the slim modiolar electrode (SME).
Study design:
Proof of concept study.
Setting:
Tertiary univer...
The global digital transformation enables computational audiology for advanced clinical applications that have the potential to impact the global burden of hearing loss. In this paper we describe emerging hearing-related artificial intelligence applications and argue for their potential to improve access, precision and efficiency of hearing health...
Purpose
In cochlear implantation (CI), the two factors that are determined by the surgeon with a potential significant impact on the position of the electrode within the cochlea and the potential outcome, are the surgical technique and electrode type. The objective of this prospective study was to evaluate the position of the slim, perimodiolar ele...
Background and objective:
Performing patient-specific, pre-operative cochlea CT-based measurements could be helpful to positively affect the outcome of cochlear surgery in terms of intracochlear trauma and loss of residual hearing. Therefore, we propose a method to automatically segment and measure the human cochlea in clinical ultra-high-resoluti...
Objectives: The aim of this study is to investigate short and long term residual hearing preservation (HP), corrected for the natural progress of hearing loss, in cochlear implant (CI) patients receiving a straight electrode array using a round window (RW) approach.
Methods: A retrospective and cross-sectional analysis on patients who received a CI...
Objectives
To report on a retrospective cohort study on the effects of expanding inclusion criteria for application of cochlear implants (CIs) on the performance 1-year post-implantation.
Methods
Based on pre-implantation audiometric thresholds and aided speech recognition scores, the data of 164 CI recipients were divided into a group of patients...
Objective:
By discussing the design, findings, strengths, and weaknesses of available studies investigating the influence of angular insertion depth on speech perception, we intend to summarize the current status of evidence; and using evidence based conclusions, possibly contribute to the determination of the optimal cochlear implant (CI) electro...
Objective: The primary aim of this study was to longitudinally compare the behavioral and self-reported outcomes of simultaneous bilateral cochlear implantation (simBiCI) and sequential BiCI (seqBiCI) in adults with severe-to-profound postlingual sensorineural hearing loss.
Design: This study is a multicenter randomized controlled trial with a 4-ye...
Objective(s):
The aim of the present meta-analysis is to assess the effects of hearing preservation (HP) methods on residual hearing in patients undergoing cochlear implant (CI) surgery and to look at the effect of follow-up time on HP outcome.
Data sources:
A systematic search was conducted in PubMed, Embase, and Cochrane Library. Only articles...
ImportanceThere is an ongoing global discussion on whether or not bilateral cochlear implantation should be standard care for bilateral deafness. Contrary to unilateral cochlear implantation, however, little is known about the effect of bilateral cochlear implantation on tinnitus.Objective
To investigate tinnitus outcomes 1 year after bilateral coc...
Prolonged deprivation of auditory feedback may negatively affect speech production accuracy, as shown by reports of reduced vowel space, changed formant values and reduced sound contrasts for challenging sounds such as sibilants in post-lingually deafened adults, compared to normal-hearing controls (e.g. Waldstein, 1990; Lane and Webster, 1990). Po...
Importance:
To date, no randomized clinical trial on the comparison between simultaneous and sequential bilateral cochlear implants (BiCIs) has been performed.
Objective:
To investigate the hearing capabilities and the self-reported benefits of simultaneous BiCIs compared with those of sequential BiCIs.
Design, setting, and participants:
A mul...
Objectives:
Usher syndrome type IIa (USH2a) is characterized by congenital moderate to severe hearing impairment and retinitis pigmentosa. Hearing rehabilitation starts in early childhood with the application of hearing aids. In some patients with USH2a, severe progression of hearing impairment leads to insufficient speech intelligibility with hea...
Objectives/hypothesis:
To investigate hearing capabilities and self-reported benefits of simultaneous bilateral cochlear implantation (BiCI) compared with unilateral cochlear implantation (UCI) after a 2-year follow-up and to evaluate the learning effect of cochlear implantees over time.
Study design:
Multicenter randomized controlled trial.
Me...
Objectives:
To investigate whether a squelch effect occurs in the first 3 years after simultaneous bilateral cochlear implantation and to investigate whether this effect increases during follow-up.
Study design:
Prospective study as part of a multicenter randomized controlled trial that compares simultaneous bilateral cochlear implantation to se...
Importance
The cost of bilateral cochlear implantation (BCI) is usually not reimbursed by insurance companies because of a lack of well-designed studies reporting the benefits of a second cochlear implant.Objective
To determine the benefits of simultaneous BCI compared with unilateral cochlear implantation (UCI) in adults with postlingual deafnes...
OBJECTIVE:
To study the cost-utility of simultaneous bilateral cochlear implantation (CI) versus unilateral CI.
STUDY DESIGN:
Randomized controlled trial (RCT).
SETTING:
Five tertiary referral centers.
PATIENTS:
Thirty-eight postlingually deafened adults eligible for cochlear implantation.
INTERVENTIONS:
A cost-utility analysis was performed from a...
To evaluate the benefit of cochlear implantation in patients with Pendred syndrome.
A retrospective study was conducted on patients who underwent cochlear implantation in our tertiary center. Speech perception was measured using a phonetically balanced wordlist at a sound pressure level of 65dB. Post-operative phoneme scores at one year for adults...
Objectives/HypothesisTo determine the effect of cochlear implantation on tinnitus perception in patients with severe bilateral postlingual sensorineural hearing loss and to demonstrate possible differences between unilateral and bilateral cochlear implantation.Study DesignProspective study.Methods
Thirty-eight adult patients were included in this p...
Poster presented at CHScom 2015 in Linköping Sweden
With expanding inclusion criteria for cochlear implantation, the number of prelingually deafened persons who are implanted as adults increases. Compared with postlingually deafened adults, this group shows limited improvement in speech recognition. In this study, the changes in health-related quality of life in late-implanted prelingually deafened...
Met de komst van evidence-based handelen is effectonderzoek steeds belangrijker geworden. Evidence-based handelen betekent ‘het gewetensvol, expliciet en oordeelkundig gebruik van het huidige beste bewijsmateriaal om beslissingen te nemen voor individuele patiënten’ (Offringa e.a., 2003) en vloeit voort uit de in de jaren tachtig ontwikkelde wetens...
Cochleaire implantatie (CI) heeft de afgelopen decennia een enorme ontwikkeling doorgemaakt. We weten dat de resultaten met CI variëren naargelang de voorgeschiedenis van de patiënt. De patiënt doorloopt binnen een multidisciplinaire setting een uitvoerige indicatiefase alvorens een uitspraak over de mogelijke meerwaarde van een CI kan worden gedaa...
The validity of a simple and not time-consuming self-assessment (SA) Scale was tested to establish progress after or during stuttering therapy.
The scores on the SA scale were related to (1) objective measures (percentage of stuttered syllables, and syllables per minute) and (2) (self-)evaluation tests (self-evaluation questionnaires and perceptual...
Unlabelled:
There is a need to evaluate the effectiveness of stuttering treatment programs delivered in domestic and international contexts and to determine if treatment delivered internationally is culturally sensitive. Evaluation of the effectiveness of the ISTAR Comprehensive Stuttering Program (CSP) within and across client groups from the Net...
In order to identify factors that are associated with voice problems and voice-related absenteeism in teachers, 1,878 questionnaires were analysed. The questionnaires inquired about personal data, voice complaints, voice-related absenteeism from work and conditions that may lead to voice complaints and absenteeism. Different factors play a role in...
In order to assess voice complaints and absence from work due to voice problems among teachers of primary and secondary education, as well as among a control group, 2,117 questionnaires were analysed. The total group consisted of 1,878 teachers and 239 controls. Female teachers more frequently reported voice complaints and absence from work due to...
Unlabelled:
A procedure for subtyping individuals who stutter and its relationship to treatment outcome is explored. Twenty-five adult participants of the Comprehensive Stuttering Program (CSP) were classified according to: (1) stuttering severity and (2) severity of negative emotions and cognitions associated with their speech problem. Speech cha...
The aim of this study was to investigate the relationship between extrinsic laryngeal muscular hypertonicity and deviant body posture on the one hand and voice handicap and voice quality on the other hand in teachers with persistent voice complaints and a history of voice-related absenteeism. The study group consisted of 25 female teachers. A voice...
Het meten van effecten is een normale activiteit in wetenschappelijke disciplines; per discipline verschilt de manier waarop. In de praktijk van de stem-, spraak- en taaltherapie moeten effecten van behandelingen worden gemeten. Wanneer zowel de therapeut als de patiënt tevreden is, zal gesproken worden van een positief effect. In de disciplines di...
Unlabelled:
This study was designed to investigate if persons who stutter differ from persons who do not stutter in the coproduction of different types of consonant clusters, as measured in the number of dysfluencies and incorrect speech productions, in speech reaction times and in word durations. Based on the Gestural Phonology Model of Browman a...
Three experiments tested the hypothesis that the deficit underlying agrammatic sentence production difficulties can be characterized as a limitation of computational resources and that these resources are not restricted to syntactic processing. This hypothesis was tested by eliciting subject-verb agreement errors in a sentence fragment completion p...
1. Inleiding De verhouding tussen het Standaard-Nederlands (SN) in Vlaanderen en Nederland en het ontstaan en de normering van variatiepatronen vormen al decennia lang het onderwerp van speculaties en weinig gefundeerde beschouwingen. De verschillen en overeen- komsten tussen en in de beide gebieden hebben dan ook onmiskenbaar tot een boeiend en ge...
With bibliogr., with a summary in Dutch. - Dissertation Radboud University Nijmegen.
