Wen Chen

Wen Chen
National Yunlin University of Science and Technology

About

456
Publications
20,795
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12,096
Citations
Citations since 2017
22 Research Items
2472 Citations
20172018201920202021202220230100200300400
20172018201920202021202220230100200300400
20172018201920202021202220230100200300400
20172018201920202021202220230100200300400

Publications

Publications (456)
Article
Full-text available
Unacceptable sagittal alignment and cement leakage are major concerns of percutaneous vertebroplasty when treating patients with painful vertebral osteoporotic compression fractures. To maintain the restored vertebral height and reduce the reliance on cement as the major stabilizer, an expandable vertebral augment system (EVA®) made of titanium all...
Preprint
Study design Reliability and agreement study Background Clinical evaluation of adolescent idiopathic scoliosis requires serial radiographic examinations. The purpose of this study was to determine whether image magnification can improve interobserver and intraobserver reliability and accuracy in the measurement of radiographic parameters of adolesc...
Article
Objective: Decreased bone mineral density as measured by dual-energy x-ray absorptiometry (DEXA) has been reported to be associated with cage subsidence following transforaminal lumbar interbody fusion (TLIF). However, DEXA is not often available or routinely performed before surgery. A novel MRI-based vertebral bone quality (VBQ) score has been d...
Article
Full-text available
When patients presenting with subjective lower limb weakness (SLLW) are encountered, it is natural to suspect a lumbar pathology and proceed with related clinical examination, investigations and management. However, SLLW could be a sign of degenerative cervical myelopathy (DCM) due to an evolving cord compression. In such circumstances, if symptoms...
Article
Background: Multiple percutaneous vertebral cement augmentation may create sandwich vertebrae. Whether the sandwich vertebra is at higher risk of further fracture remains unknown. Objective: To compare the incidence of further fractures of sandwich vertebrae and adjacent vertebrae and to identify potential risk factors for sandwich vertebral fra...
Article
Full-text available
Indium tin oxide (ITO) film is the most widely used as front electrodes in solar cells with a copper metallization scheme. No work has focused on the barrier properties of the ITO layer on the textured silicon for solar cells. In this work, a thin indium tin oxide barrier layer and copper metal layer were deposited on textured (001) silicon by a sp...
Article
Full-text available
The authors would like to acknowledge the following funding information that was missing in the original article. This study was funded by Chang-Gung Memorial Hospital (Grant CORPG3H0261, representing hospital funding). The funding body did not have any role in the design of the study or in data collection, analysis and interpretation or in writing...
Preprint
Full-text available
Background We investigated whether spinopelvic parameters are important prognostic factors causing adjacent segment degeneration (ASD) after long instrumented spinal fusion for degenerative spinal disease. Methods This uncontrolled, randomized, single arm retrospective study included patients who underwent long instrumented lumbar fusion (fusion le...
Preprint
Full-text available
Purpose We investigated whether spinopelvic parameters are important prognostic factors for adjacent segment degeneration after long instrumented spinal fusion for degenerative spinal disease. Methods This uncontrolled, randomized, single arm retrospective study included patients who underwent long instrumented lumbar fusion (fusion levels≥ 4) in t...
Article
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Background: The optimal anchor density in adolescent idiopathic scoliosis (AIS) surgery to achieve good curve correction remains unclear. The purpose of the study is to analyze the correlations between three-dimensional curve correction and anchor density in the pedicle screw-based posterior fusion of AIS. Methods: One hundred and twenty-seven A...
Article
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Background: The risk of posterior cage migration (PCM) exists when a fusion cage is used for transforaminal lumbar interbody fusion (TLIF). This complication is influenced by contact pressure between the endplate and the cage. Previous reports demonstrated that anteriorly located cages bore more load and had greater strain than posteriorly located...
Article
Background: The postoperative infection rates for transforaminal lumbar interbody fusion (TLIF) have ranged from <2% to 4%. However, no consensus has been reached on the treatment strategies. TLIF cage preservation or revision surgery for lumbar spine reconstruction are 2 possible treatments. We aimed to determine the most effective method for org...
Article
Full-text available
Purpose Tandem spinal stenosis (TSS) refers to lumbar and cervical spinal canal stenosis. Staged surgery is often chosen, but sometimes, mere decompression of one stenosis is adequate to relieve symptoms. Therefore, we intend to analyze whether starting with the cervical or the lumbar region is the most logical option. Methods We retrospectively r...
Article
Full-text available
Background Cervical spine infections are uncommon but potentially dangerous, having the highest rate of neurological compromise and resulting disability. However, the factors related to surgical success is multiple yet unclear. Methods We retrospectively reviewed the medical records of 27 patients (16 men and 11 women) with cervical spine infectio...
Article
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Background Traditionally, nonoperative management with long-term antibiotics and bed rest has been recommended as first-line treatment for most patients with postoperative discitis. A recent trend in treatment under a limited range of indications has been to perform surgical débridement followed by long-term administration of antibiotics. This desc...
Article
Full-text available
Background Correcting the scoliosis and stabilizing the spine in the corrected position is the basis of treatment for adolescent idiopathic scoliosis (AIS). Spinal instrumentation and derotation are the principle steps of surgery for any type of AIS. A perspicuous understanding needs to be attained regarding derotation maneuvers in practice; theref...
Article
Full-text available
Background Adolescent idiopathic scoliosis, in which obvious curves are visible in radiographic images, is also seen in combination with lumps in the back. These lumps contribute to inclination, which can be measured by a scoliometer. To the authors’ knowledge, there are no previous formulas combining thoracic and lumbar scoliometer values simultan...
Article
Pure TiO2 nanoparticles, TiO2/9 wt %CNT and TiO2/18 wt %CNT nanocomposites were fabricated by sol-gel method and the CNTs in TiO2/CNT nanocomposite were grown under the catalysis of Ni film in thermally chemical deposition process. The TiO2/CNT was characterized and analyzed by field-emission scanning electron microscope, transmission electron micr...
Article
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In this work, nickel thin films were deposited on texture silicon by electroless plated deposition. The electroless-deposited Ni layers were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive x-ray spectroscopy (EDS), X-ray diffraction analysis (XRD), and sheet resistance measurement. The...
Conference Paper
Full-text available
Introduction: Elderly patients with chronic un-resolving symptoms due to degenerative spine disease are more prone to have poor surgical outcomes. They also predispose for hardware related complications, especially following long spinal fusions. Considering the possibility of poor outcomes, treating these conditions cannot be ignored but rather a p...
Article
In this study, the hydrothermal method was used for synthesizing ZnSe/graphene nanocomposites with the amount of graphene oxide (GO) and hydrazine. Obtained ZnSe/graphene photocatalysts were characterized by X-ray diffraction analysis (XRD) and transmission electron microscope (TEM). Photocatalytic activity under visible light is evaluated in methy...
Article
Full-text available
Based on our previous finding of a seven-miRNA (hsa-miR-34a, miR-449a, miR-564, miR-432, miR-548d, miR-572 and miR-652) signature as a potential biomarker for schizophrenia, this study aimed to examine if hospitalization could affect expressions of these miRNAs. We compared their expression levels between acute state and partial remission state in...
Article
In this work, the hydrothermal method was used for synthesizing Pt-TiO2/graphene nanocomposites. Obtained Pt-TiO2/graphene photocatalysts were characterized by Raman spectroscopy, X-ray diffraction analysis (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FTIR) spectroscopy, photolum...
Article
In this work Pt nanoparticles on graphene (PtNPs/GN) were formed from graphite oxide by two routes (one-step and two-step routes). For one-step route, a fixed weight of graphene oxide (GO) and a variable weight of H2PtCl6·6H2O were put in ethylene glycol for a reflux at 120 and 150 °C for 3, 6, 12 and 24 h, respectively. For the two-step route, the...
Article
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Background: Elevated plasma C-reactive protein (CRP) levels can be used to predict an increased risk of future atrial fibrillation (AF). However, several single polynucleotide polymorphisms (SNPs) in the CRP gene affect CRP levels. This study aims to elucidate the correlation between CRP gene polymorphisms and the risk of AF among a Chinese popula...
Conference Paper
In this work, we compared the decouple plasma nitridation (DPN) and post nitridation anneal (PNA) processes for equivalent oxide thickness (EOT) scaling of ALD hafnium zirconate (HfZrO2) gate dielectric. Detailed physical, optical and MOSCAP electrical characteristics of HfZrON film were studied. It is found that DPN power parameter tuning could yi...
Article
Zinc oxide thin films were prepared in electrodeposition baths with three electrodes. The work electrode is a silicon substrate coated with Pd metal by sensitization and activization process. The work electrode is kept at -1.9 voltage v.s saturated calomel electrode. The electrodeposition baths contain ZnCl2 (4 mM) and KCl (50 mM) as host compositi...
Article
In this letter, we have demonstrated that cryogenic implant in the source and drain formation offers advantages for reducing the threshold voltage mismatch in pMOSFET. A discrete dopant profiling method is used to verify the presence of boron out-diffusion from the drain, which further induces the random dopant fluctuation. Results show that this b...
Article
To develop and validate prediction rules to identify the risk of methicillin-resistant Staphylococcus aureus (MRSA) infection among community patients who have healthcare-associated (HA) exposure and S. aureus bacteremia. A total of 1,166 adults with community-onset S. aureus bacteremia were retrospectively enrolled. The background prevalence of co...
Conference Paper
Advanced junction scaling with device performance gain, leakage reduction and reduced threshold voltage (Vth) variation are critical for CMOS 28nm node and future scaling. In this paper, implant induced defect engineering for higher drive current with reduced SRAM defectivity, advanced junction formation and Vth mismatch (Vtmin) on a state-of-the-a...
Article
The electroless NiCoFeP films were deposited on a silicon substrate in a bath containing Ni2+, Co2+, and Fe2+ ions with a concentration ratio of 1:1.9:1.2. These films were characterized by using transmission electron microscope, energy dispersive X-ray spectrometer, and alternating gradient magnetometer for their microstructure, crystal structure,...
Article
Various electroless Ni–Co–P films were deposited on silicon substrates in electroless baths using sodium hypophosphite as reducing agent and nickel and cobalt sulfates as ion source at pH value of 9 and temperature from 55 to 85 °C. The effect of the atomic ratio of Co to Ni + Co in baths on the growth behavior of the electroless Ni–Co–P films was...
Article
A new band at 23 390 cm−1 in the A˜1Πu–X˜1Σg+ electronic transition of C3 has been recorded by laser-induced fluorescence at high resolution and rotationally analyzed. Based on the agreement of the lower state constants with infra-red data given by Kawaguchi et al. [9], the vibrational assignment is found to be 0 1 1(Δu)–0 1 1 (Πg). Seventeen of th...
Article
Full-text available
ABSTRATE Carbon nanotubes (CNTs) were grown by electroless Ni-P plated on silicon substrate in a microwave heating chemical vapor deposition (CVD) system with methane gas at 700 °C. The CNTs grown on Ni–P catalyst showed random orientation and small diameter around 15–30 nm. Field emission test results indicated that the Ni–P catalyzed-CNTs exhibit...
Article
Full-text available
Background: The impact of conventional cardiovascular (CV) risk factors on acute myocardial infarction (AMI) defined by the universal definition published in 2007 hasn't been evaluated in young population in Taiwan according to the comparison of their prevalence between young AMI patients and age- and sex-matched contemporary controls. Methods: AMI...
Article
Patients with schizophrenia frequently display neurocognitive dysfunction, and genetic studies suggest it to be an endophenotype for schizophrenia. Genetic studies of such traits may thus help elucidate the biological pathways underlying genetic susceptibility to schizophrenia. This study aimed to identify loci influencing neurocognitive performanc...
Article
An imbalance between T Helper 1 (T(H)1) and T Helper 2 (T(H)2) cytokine production is important for the pathogenesis of systemic lupus erythematosus (SLE). We aimed to investigate gene-gene associations of T(H)1 and T( H)2 cytokines genes in Chinese patients with SLE. Twenty single nucleotide polymorphisms (SNPs) in eight cytokines genes were genot...
Article
An electroless Ni–P film was first deposited on a spiegel-iron plate and then annealed by an Nd:YAG pulsed wave laser. In order to obtain the optimal laser annealing parameters for maximizing the hardness and minimizing the surface roughness of electroless Ni–P films, the Taguchi method and grey system theory were used to analyze the experimental d...
Article
Chromosome 6p is one of the most commonly implicated regions in the genome-wide linkage scans of schizophrenia, whereas further association studies for markers in this region were inconsistent likely due to heterogeneity. This study aimed to identify more homogeneous subgroups of families for fine mapping on regions around markers D6S296 and D6S309...
Article
Smooth muscle tumors are uncommon in the urinary bladder, and atypical leiomyoma of the urinary bladder is extremely rare. We report a case of atypical leiomyoma with a concurrent breast carcinoma and discuss the pathologic features, the possible etiology and clinical outcome of the tumor.
Article
Abstract Although the individual effect ofhyperbaric oxygen (HBO) and pulsed low-intensity ultrasound (PLIUS)on OA chondrocyte has been reported, the effects ofHBO combined with PLIUS treatment are unknown. Our data suggested that ultrasound and HBO treatment increased cell bioactivity of OA chondrocytes. Real-time quantitative polymerase chain rea...
Article
A structure of Cu/ITO(10 nm)/Si was first formed and then annealed at various temperatures for 5 min in a rapid thermal annealing furnace under 10−2 Torr pressure. In Cu/ITO(10 nm)/Si structure, the ITO(10 nm) film was coated on Si substrate by sputtering process and the Cu film was deposited on ITO film by electroplating technique. The various Cu/...
Article
This study examined the relations of genetic variants in catechol-O-methyltransferase (COMT) gene, including rs737865 in intron 1, rs4680 in exon 4 (Val158Met) and downstream rs165599, to schizophrenia and its related neurocognitive functions in families of patients with schizophrenia. Totally, 680 individuals from 166 simplex (166 affected members...
Article
The electroless Ni–Co–P films were deposited on Fe film in plating baths using sodium hypophosphite as reducing agent and nickel and cobalt sulphates as ion source at pH value of 9 and plating temperature from 60 to 85 °C. The effect of the mol ratio of CoSO4/CoSO4 + NiSO4 in plating bath on the growth behavior of electroless Ni–Co–P films was stud...
Article
We have compared the device performance of double-quantum-barrier charge-trapping memory of a TaN/Ir3Si-[HfAlO-LaAlO3]-HfON0.2-[HfAlO-SiO2]-Si device with single barrier non-volatile memory MONOS devices at close EOT. At 150°C under fast 100 ¿s and low ±9 V P/E, the double-quantum-barrier charge-trapping device shows a 3.2 V initial ¿Vth and 2.7 V...
Article
Full-text available
We report Ir/TiO<sub>2</sub>/TaN metal-insulator-metal capacitors processed at only 300degC, which show a capacitance density of 28 fF/mum<sup>2</sup> and a leakage current of 3 times 10<sup>-8</sup> (25degC) or 6 times 10<sup>-7</sup> (125degC) A/cm<sup>2</sup> at -1 V. This performance is due to the combined effects of 300degC nanocrystallized hi...
Article
Ni–P film was electrolessly deposited on Fe/Si substrate in an acid plating bath containing nickel sulfate as the nickel source and sodium hypophosphite as a reducing agent. The Fe film in Fe/Si substrate was formed by electron-beam evaporation deposition. The Ni–P film was characterized by transmission electron microscopy. The results showed that...
Article
Full-text available
We describe a programmable-erasable MIS capacitor with a single high-k Hf<sub>0.3</sub>N<sub>0.2</sub>O<sub>0.5</sub> dielectric layer. This device showed a capacitance density of ~6.6 fF/mum<sup>2</sup>, low program and erase voltages of +5 and -5 V, respectively, and a large DeltaV<sub>fb</sub> memory window of 1.5 V. In addition, the 25degC data...
Article
Full-text available
Calcineurin is a calcium/calmodulin-dependent protein phosphatase composed of two subunits, a regulatory subunit of calcineurin B (CNB) and a catalytic subunit of calcineurin A (CNA). PPP3CC is the gamma isoform of CNA located at the chromosome 8p21.3 region. To evaluate the association between PPP3CC and schizophrenia in the Taiwanese population,...
Article
In this work, an electroless CoWP film deposited on a silicon substrate as a diffusion barrier for electroless Cu and silicon has been studied. Four different Cu 120 nm/CoWP/Si stacked samples with 30, 60, 75, and 100 nm electroless CoWP films were prepared and annealed in a rapid thermal annealing (RTA) furnace at 300°C to 800°C for 5 min. The fai...
Article
In this work a novel method for the growth of Zinc Oxide nanowire was provided. The ZnO nanowires were grown on Ni/Cu–Zn/SiO2/Si substrate in H2O/ O2/CH4 atmosphere. The substrate was prepared by the following steps. The Si chip was first grown a SiO2 layer on its surface in air at 1000 °C for 15 min in a general furnace. On this SiO2 layer a layer...
Article
A Cu–Zn alloy with about 30 wt.% Zn was used as substrate for the growth of nanosized zinc oxides (ZnO). Before growth of ZnO, a Ni layer was coated on the substrate by electrodeposition technique. This Ni layer was used as a barrier against the diffusion of Zn and as a promoter for the growth of nanosized ZnO. The variables for the ZnO growth cont...
Article
Evidence for association with schizophrenia has been reported for NOTCH4, although results have been inconsistent. Previous studies have focused on polymorphisms in the 5' promoter region and first exon of NOTCH4. Our aim was to test the association of the entire genomic region of NOTCH4 in 218 families with at least two siblings affected by schizo...
Article
In this work carbon nanotubes were first grown on copper substrate by chemical vapor deposition method. The Sn deposits were then deposited on the surface of as-grown carbon nanotubes by three different methods: electroplating, electroless plating and displacing methods. The Sn deposits on CNTs surface were characterized by both scanning electron m...
Article
Genetic study on metabolic syndrome is a great challenge, due to its complex traits and the pleiotropic manifestation of atherosclerosis. Familial aggregation and recurrence risk ratio can provide the insight of possible genetic mechanism. The Chin-Shan community family study was based on adolescent probands and their relatives (1356 subjects) who...
Article
Nanosized ZnOs were synthesized on the surface of α brass coated a film of nickel catalyst at 500–700°C under atmosphere of O2 and CH4 gases. The nanosized ZnOs have shapes including pillar, leaf, sheet and rod, which were determined by the synthesis temperature and the flow rates of O2 and CH4 gases. The nanosized ZnOs were characterized by electr...
Article
In this work, the effect of tin-doped indium oxide (ITO) film as capping layer on the agglomeration of copper film and the appearance of copper silicide was studied. Both samples of Cu 100nm/ITO 10nm/Si and ITO 20nm/Cu 100nm/ITO 10nm/Si were prepared by sputtering deposition. After annealing in a rapid thermal annealing (RTA) furnace at various tem...
Article
In this work a thin film of electroless Ni was deposited on the surface of commercial acrylic spheres about 4 μm in size. After the acrylic spheres were cleaned, sensitized and activated successively, they were put into an acid plating bath containing sodium hypophosphite as reducing agent for the electroless Ni deposition. The acrylic spheres with...
Article
In this work the small amounts of NiSO4 was added to a basic electroless plating bath of CoSO4 with Na2H2PO2 as reducing agent for the deposition of Co Ni P film on a silicon substrate. The initial growth behavior, containing plating rate, chemical composition, crystal structure, surface morphology and micro-structure, of the electroless plating fi...
Article
We demonstrate a high-performance TaN SrTiO3 TaN metal-insulator-metal (MIM) radio-frequency (rf) capacitor with good device integrity of very high capacitance density of 44 fFμ m2, small voltage linearity α of 54 ppm V2 at 2 GHz, and a small capacitance reduction 3.5% from 100 KHz to 10 GHz. Such large capacitance density can largely reduce the de...
Article
Full-text available
Acute heart failure leads to high mortality and morbidity rates. The symptom of acute dyspnoea is non-specific and the diagnostic tools of acute heart failure are still not satisfactory. Tissue Doppler echocardiography is accurate in evaluating cardiac function; however, its efficacy in diagnosing patients with acute dyspnoea in emergency departmen...
Article
In this work the effect of tin-doped indium oxide (ITO) film thickness on the diffusion barrier between silicon and copper was studied. Four different Cu (100 nm)/ITO/Si samples with 10, 20, 40 and 60 nm ITO were prepared by sputtering deposition. After annealing in a rapid thermal annealing furnace at various temperatures for 5 min, samples were c...
Article
Full-text available
A very high density of 35 fF=m 2 is measured in a radio frequency (RF) metal-insulator-metal (MIM) capacitor using high-(= 169) SrTiO3 fabricated by very large scale integration (VLSI) back-end integration. A very small capacitance reduction of 4.1% from 100 kHz to 10 GHz, low leakage current of 1210 07 A/cm 2 at 1 V are simultaneously measured. Th...
Article
Full-text available
TaN/SrTiO<sub>3</sub>/TaN capacitors with a capacitance density of 28-35 fF/mum<sup>2</sup> have been developed by using a high-kappa (kappa=147-169) SrTiO<sub>3</sub> dielectric containing nanometer-sized microcrystals (3-10 nm). A small capacitance effective thickness was achieved by reducing the interfacial TaON using N<sup>+ </sup> treatment on...
Article
The sensitization, activation, nucleation and growth of electroless Ni–P deposition on silicon in an acid plating bath with sodium hydrophosphite as reducing agent and sodium succinate as complexing agent were studied by transmission electron microscopy, field emission scanning electron microscopy and atomic force microscopy. The results show that...