Weerasak ChonchaiyaChulalongkorn University · Department of Pediatrics
Weerasak Chonchaiya
MD
About
49
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Introduction
Additional affiliations
September 2007 - June 2021
Publications
Publications (49)
Aim
The aim of the study was to examine the relationship between sleep problems and executive functions in pre‐school children as reported by parents/caregivers.
Methods
This cross‐sectional study of caregiver‐child dyads was conducted in a public kindergarten school in Northern Thailand. Sleep problems were evaluated using the Children's Sleep Ha...
Positive parenting programmes (PPP), albeit effective, are not readily accessible to the general public, particularly during the COVID-19 pandemic. In 103 healthy caregiver-child dyads, we investigated the effectiveness of online PPP on parenting sense of competencies (primary outcome), parenting styles and behavioural concerns of children aged 3–6...
Sibling bullying is an unwanted aggressive behavior of a sibling that is associated with peer bullying and emotional problems. However, the prevalence of sibling bullying, the factors that affect this condition, and its impact on depression and self-esteem are understudied, especially in Thailand. This study aims to examine the prevalence of siblin...
Screen media use in hospitalized children is more prevalent than such media use in a home setting. Research on characteristics and extent to which screen media are used in hospitalized children in addition to associated factors is scarce. This study aims to examine the duration and factors associated with screen media use in hospitalized children....
Positive parenting programmes (PPP), albeit effective, are not readily accessible to the general public, particularly during the COVID-19 pandemic. In 103 healthy caregiver-child dyads, we investigated the effectiveness of online PPP on parenting sense of competencies (primary outcome), parenting styles and behavioural concerns of children aged 3–6...
• Prevalence of insomnia is often underestimated in primary care pediatric practice and the rate of such a problem is likely to be increasing, particularly during the COVID-19 pandemic.
• Cognitive-behavioral therapy (CBT) and other behavioral interventions are the mainstay for the management of pediatric insomnia.
• There is no FDA-approved medi...
Background
A technology-based intervention, such as a mobile application, was a growing interest and potentially effective modality for treating obesity. The study aimed to evaluate the effectiveness of the OBEST, a new mobile/tablet-based application in reducing weight and encouraging healthy eating behaviors and quality of life in children with o...
Screen media multitasking (SMM), the act of exposure ≥ 2 screen media simultaneously, is increasing nowadays. Single media use was associated with child’s behavioural problems in previous studies. However, the associations between SMM since early childhood and behavioural problems in school-age children had not been elucidated. This study aimed to...
Background:
Although higher sleep problems were mostly reported in children with autism spectrum disorder (ASD) compared with typically developing (TD) children, particularly in Western countries, such evidence is relatively scarce in developing countries. We therefore investigated sleep difficulties in Thai children aged 3-16 years with ASD compa...
Aims
Treatment of childhood and adolescent obesity is challenging. Smartphone applications have been widely used as a modality of obesity treatment. The study aimed to evaluate the effectiveness of tablet/smartphone-based (OBEST) application added to standard treatment of obesity.
Methods
A randomized controlled trial was conducted in 77 obese chi...
A computerized version of "Noo-Khor-Arn" `May I read?', a paper-based screening test for Thai children at risk with Learning Disability (LD), was developed and some core ideas of development were given in details. Six test categories with 23 subtests were conducted on 110 Thai children aged between 7-12 years old (Mean = 7.94, SD = 1.45), divided i...
Associations between screen media and child cognition are complex. This study aimed to examine whether age of onset of media exposure, cumulative effect of high media exposure, and verbal interaction during screen time in the first 2 years of life were associated with 4-year-old cognition by including parenting behaviors into the final construct.
T...
Although behavioral problems have been observed in children and adolescents with perinatally-acquired HIV infection (PHIV), behavioral information regarding younger PHIV children are scarce. This study aims to identify behavioral problems in PHIV and HIV-exposed uninfected (HEU) children and to evaluate factors associated with such problems. A pros...
Aim:
This study examined long-term associations between mother-child interactions and parenting styles and electronic screen time.
Methods:
We studied 280 healthy children (53.2% girls) enrolled at a mean age of 36 ±0.4 months from February 2015 to September 2016. The study included retrospective data on 267 children who had been recruited from...
Introduction
Antiretroviral therapy (ART) is recommended in perinatally HIV‐infected (PHIV) infants immediately upon diagnosis. We aimed to compare neurodevelopmental outcomes between PHIV children who initiated ART within 12 months of life and perinatally HIV‐exposed uninfected (PHEU) children and to assess neurodevelopmental outcomes by timing of...
Background
The exact cause and mechanisms underlying the pathobiology of autism spectrum disorder (ASD) remain unclear. Dysregulation of long interspersed element-1 (LINE-1) has been reported in the brains of ASD-like mutant mice and ASD brain tissues. However, the role and methylation of LINE-1 in individuals with ASD remain unclear. In this study...
Background
Alu elements are a group of repetitive elements that can influence gene expression through CpG residues and transcription factor binding. Altered gene expression and methylation profiles have been reported in various tissues and cell lines from individuals with autism spectrum disorder (ASD). However, the role of Alu elements in ASD rema...
Background
Video game playing is a favorite leisure activity amongst children worldwide. Individuals with attention‐deficit/hyperactivity disorder (ADHD) often lack of self‐control which make them at risk for substance abuse and game addiction. However, there have been conflicting results between studies on the pattern of video gaming and game addi...
Objectives: There are increasing reports of younger children accessing media and screen. This study aims to describe screen use in pre-school children and its association with externalising problems.
Methods: A cross-sectional study of pre-schoolers aged two to five years was conducted. Their caregivers were asked to provide data regarding screen u...
Aims:
Currently, television and new forms of media are readily available to children and adolescents in their daily lives. Excessive use of media can lead to negative physical and psychosocial health effects. This study aimed to describe children's media use, including media multitasking, as well as the associations between media use and their psy...
Background:
Little is known about the effect of screen time and sleep at a younger age on current sleep outcome in infants. We therefore examined whether sleep parameter at a younger age and daily exposure of electronic media could predict sleep outcomes in 12-month-old Thai infants.
Methods:
There were 208 typically developing infants enrolled...
This study aimed to validate the use of two-step Modified Checklist for Autism in Toddlers (M-CHAT) screening adapted for a Thai population. Our participants included both high-risk children with language delay (N = 109) and low-risk children with typical development (N = 732). Compared with the critical scoring criteria, the total scoring method (...
This study compares sleep disturbances in Thai children aged 5-12 years with attention-deficit hyperactivity disorder (ADHD) and typically developing children using the Children's Sleep Habits Questionnaire (CSHQ)-Thai version. Fifty-five children with ADHD and 110 typically developing children were enrolled. Their parents completed the CSHQ, the A...
Background: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental and behavioral disorder commonly prevalent in school-aged children. ADHD can be a comorbid diagnosis in those with epilepsy. However, the relationship between ADHD and epilepsy is complex and not entirely known. Objectives: To compare the prevalence of ADHD between...
Background: Sleep problems can have a significant effect on children behaviors, emotional and cognitive developments. However, limited information is available regarding the sleep behaviors and sleep problems of school-aged children in Thailand. The purposes of this study were to examine the prevalence of sleep problems and to describe sleep/wake p...
AimTo investigate whether trends of TV exposure from age six to 18 months and adult TV programmes were associated with behavioural concerns of 18-month-old Thai toddlers.Methods
There were 194 healthy infants recruited at age six months and followed-up until 18 months of age in this present cohort. TV exposure variables were assessed by interviewin...
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder commonly prevalent in children worldwide including Thailand. However, there are very few studies thus far addressing risk factors for ASD in Thai children. This case-control study aims to investigate whether various risk factors especially socioeconomic status, advanced p...
AimTo investigate whether evening media exposure, bedroom media use, and night-time sleep duration at age of six months are associated with night-time sleep duration in 12-month-old Thai infants.Methods
We enrolled 208 infants in this study at six-months-of-age. They were followed-up at 12-months-of-age. A sleep diary was used to document the infan...
Auditory processing capabilities at the subcortical level have been hypothesized to impact an individual's development of both language and reading abilities. The present study examined whether auditory processing capabilities relate to language development in healthy 9-month-old infants. Participants were 71 infants (31 boys and 40 girls) with bot...
The relative risk of immune-mediated disorders (IMDs) among women carriers of premutation alleles is estimated by a survey for IMDs among 344 carrier women (age 19-81 years; mean 46.35 and SD 12.60) and 72 controls (age 18-87 years; mean 52.40 and SD 15.40). One hundred fifty four (44.77%) women carrier had at least one IMD, as did 20 controls (27....
Young children with fragile X syndrome (FXS) often experience anxiety, irritability, and hyperactivity related to sensory hyperarousal. However, there are no medication recommendations with documented efficacy for children under 5 years old of age with FXS. We examined data through a chart review for 45 children with FXS, 12-50 months old, using th...
Seizures are a common co-occurring condition in those with fragile X syndrome (FXS), and in those with idiopathic autism spectrum disorder (ASD). Seizures are also associated with ASD in those with FXS. However, little is known about the rate of seizures and how commonly these problems co-occur with ASD in boys with the FMR1 premutation. We, theref...
To examine the pattern and extent of television viewing in children with autism spectrum disorder (ASD) compared with typically developing controls and those with delayed language development (DLD).
Fifty-four individuals with ASD (mean age 2.56 ± 0.66 years) and 84 controls (mean age 2.43 ± 0.81 years) were enrolled. Fifty-six individuals with DLD...
An increased prevalence of autoimmune diseases in family members of children with autism spectrum disorders (ASD) has been previously reported. ASD is also a common problem co-occurring in children with fragile X syndrome (FXS). Why ASD occurs in some individuals with FXS, but not all, is largely unknown. Furthermore, in premutation carrier mothers...
Minocycline can rescue the dendritic spine and synaptic structural abnormalities in the fragile X knock-out mouse. This is a review and preliminary survey to document side effects and potential outcome measures for minocycline use in the treatment of individuals with fragile X syndrome. We surveyed 50 patients with fragile X syndrome who received m...
Chonchaiya W, Nguyen DV, Au J, Campos L, Berry-Kravis EM, Lohse K, Mu Y, Utari A, Hervey C, Wang L, Sorensen P, Cook K, Gane L, Tassone F, Hagerman RJ. Clinical involvement in daughters of men with fragile X-associated tremor ataxia syndrome.
Women with the fragile X mental retardation 1 (FMR1) premutation often have concerns about neurological and...
There is a broad spectrum of clinical involvement throughout the generations in families affected by the fragile X mutations, both the full mutation and the premutation. A careful family history, assessment, and genetic counseling should lead to better treatments in all individuals affected by the many manifestations of these mutations. Individuals...
The mutations in the FMR1 gene have been described as a family of disorders called fragile X-associated disorders including fragile X syndrome, fragile X-associated tremor/ataxia syndrome, primary ovarian insufficiency, and other problems associated with the premutation, such as hypothyroidism, hypertension, neuropathy, anxiety, depression, attenti...
Background: Obese children may attain skeletal maturation earlier than normal weight children, but the relation between body fat and physical maturation including adult height has not been clarified. Objective: To identify impact of obesity on predicted adult height and height gain. Materials and methods: Sixty two obese children (38 males and 24 f...
To identify impact of television viewing on language development.
The case-control study included 56 new patients with language delay and 110 normal children, aged 15-48 months. Language delay was diagnosed by reviewing language milestones and Denver-II. Television viewing variables and child/parental characteristics between both groups were interv...