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Publications (30)
Objectives
Defecation disorders are a common pediatric problem and bowel frequency is crucial in identifying them. The aim of this analysis is to define normal bowel frequencies in healthy children ranging from newborns to adolescents.
Methods
A literature search was conducted using MEDLINE, SCOPUS, EMBASE, Cochrane Library, and Web of Science fro...
Background
The Rome criteria define childhood functional constipation but do not address refractory constipation. Attempts to define refractory constipation lack consensus. The interchangeable use of ‘refractory’ and ‘intractable’ or ‘therapy-resistant’ constipation and lack of understanding of the therapeutic ceilings before this diagnosis complic...
Objective
Lack of physical activity (PA) and sedentary behaviour (SB) have emerged as critical global health concerns in children and are believed to be associated with functional constipation (FC). The present study aims to explore this potential association.
Design
A comprehensive search of PubMed, Scopus, Web of Science, Embase, Cochrane Librar...
Background:
Epidemiological data on pediatric inflammatory bowel disease (PIBD) have been reported in Asian countries. However, short-term follow-up data, especially in Southeast Asian countries, are limited.
Purpose:
Analyze and compare the baseline and 1-year follow-up (1FU) data for PIBD in Asian children.
Methods:
The multinational network...
Objectives: The gut-brain
axis, a complex communication system
between the brain and the gastrointestinal tract, indicates that
disturbances in the gut can disrupt the nervous system's regulation
of sleep. Conversely, sleep deprivation can exacerbate symptoms of
irritable bowel syndrome (IBS). This study aims to assess the quality
of sleep and its...
Infantile onset-Inflammatory Bowel Disease (IO-IBD), diagnosed before two years of age, exhibits elevated familial predisposition and primarily colon involvement, as evidenced by previous literature. Moreover, limited therapeutic efficacy and heightened surgical interventions are observed relative to late onset-IBD. We presents ten cases identified...
In children, the prevalence of Inflammatory Bowel Disease (IBD) is on the rise, presenting a diagnostic challenge. Magnetic resonance enterography (MRE) is a highly effective and non-invasive technique for evaluating and monitoring intestines in IBD patients. MRE facilitates intestine visualization enabling accurate diagnosis, assessment of disease...
Pediatric inflammatory bowel disease (PIBD) has traditionally been prevalent in Western regions, but its incidence is rising globally, particularly in pediatric cases. Our study, conducted in Sri Lanka, a developing country in South Asia experiencing a surge in PIBD cases, aims to address the unique clinical presentations and the complications at d...
Pediatric Inflammatory Bowel Disease (PIBD) is becoming more common, even in middle-income countries like those in South Asia. The increase in diagnosed patients of PIBD reflects a global trend of Inflammatory Bowel Disease (IBD) affecting regions where its incidence was previously low. It is important to understand how PIBD affects the quality of...
Background
Therapy-resistant constipation often is a frustrating clinical entity recognised by the persistence of infrequent and painful bowel movements faecal incontinence and abdominal pain despite intensive treatment. It is important to clearly define therapy-resistant constipation before children are subjected to invasive diagnostic and therape...
Introduction - Infantile onset-Inflammatory Bowel Disease (IO-IBD), diagnosed before two years of age, exhibits elevated familial predisposition and primarily colonic engagement, as evidenced by previous literature. Moreover, limited therapeutic efficacy and heightened surgical interventions are observed relative to late onset-IBD. This study prese...
Introduction:
Disorders of Gut-Brain Interactions (DGBI) are a common clinical problem in children and pose significant challenges to the attending pediatrician. Radiological investigations are commonly ordered to evaluate these children.
Area covered:
This review focuses on the current best practice of using radiological investigations in DGBIs...
Objective: Normal bowel frequency is considered as the key indicator of bowel health. We conducted a meta-analysis with a meta-re- gression to assess the normal bowel frequency of healthy children. We aimed to create a normative data set for bowel frequency for children from birth to 18 years using the existing literature.
Methods: A literature sea...
Objective: Portal hypertension is a complex condition characterised by increased venous pressure in the portal venous system, resulting from both cirrhotic and non-cirrhotic conditions. While numerous studies have explored portal hypertension in adults, limited research has focused on pediatric patients, particularly in Sri Lanka. This study aims t...
Functional diarrhea in children is a disease that has been focused on by both general pediatricians as well as pediatric gastroenterologists across the world. Although it is seen across the pediatric age group from late infancy to adolescence, most still believe that functional diarrhea only occurs in younger children. Recent epidemiological studie...
Introduction. Mucormycosis is a severe angio-invasive fungal infection caused by mucormycetes, a group of fungi that are ubiquitous in the environment. The incidence of mucormycosis has been surging rapidly due to the global corona virus disease 2019 (COVID-19) pandemic.
Gap Statement. The complete picture of the causative fungi associated with muc...
Pathogenesis of dengue haemorrhagic fever is not fully understood, but it is thought that there is antibody enhancement during the secondary infection, which causes severe dengue haemorrhagic fever (DHF). Therefore, patients who have DHF should have a documented history of symptomatic dengue infection in the past. A retrospective descriptive-analyt...
Background:
Sri Lanka boasts high rates of early and exclusive breastfeeding. Perceived inadequacy of milk, a global problem, is the main cause for early cessation of breastfeeding. Research Aims: The aims of this study are to (a) determine the prevalence, (b) identify the risk factors, and (c) ascertain the association that maternal psychological...
Introduction: Patient transport remains a necessary facet of today's health care environment and transport conditions bear a major impact on the outcome. There is a recent move in Sri Lanka to establish retrieval teams. Thus, identifying problems faced by the present system will be of utmost importance in development of transport teams. Objective:...
To assess the health related quality of life (HRQoL) and somatization in school children with constipation.
This cross-sectional survey was conducted in children aged 13-18 years, in 4 schools in Gampaha district of Sri Lanka. Data were collected using a pretested, self-administered questionnaire with questions on bowel habits, somatization, and HR...