Walter E Babiec

Walter E Babiec
University of California, Los Angeles | UCLA · Undergraduate Interdepartmental Program for Neuroscience

PhD

About

13
Publications
4,213
Reads
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117
Citations
Education
July 2005 - May 2011
University of California, Los Angeles
Field of study
  • Neurobiology
September 1990 - September 1995
Massachusetts Institute of Technology
Field of study
  • Mechanical Engineering

Publications

Publications (13)
Article
Full-text available
The 2019 Society for Neuroscience Professional Development Workshop on Teaching reviewed current tools, approaches, and examples for teaching computation in neuroscience. Robert Kass described the statistical foundations that students need to properly analyze data. Pascal Wallisch compared MATLAB and Python as programming languages for teaching stu...
Article
Full-text available
Although long thought to simply be a source of synaptic noise, spontaneous, action potential-independent release of neurotransmitter from presynaptic terminals has multiple roles in synaptic function. We explored whether and to what extent the two predominantly proposed mechanisms for explaining spontaneous release, stochastic activation of voltage...
Article
Full-text available
Behavioral, physiological, and anatomical evidence indicates that the dorsal and ventral zones of the hippocampus have distinct roles in cognition. How the unique functions of these zones might depend on differences in synaptic and neuronal function arising from the strikingly different gene expression profiles exhibited by dorsal and ventral CA1 p...
Article
Full-text available
Dephosphorylation of AMPA receptor (AMPAR) GluA1 subunits at two sites, serine 845 (S845) and threonine 840 (T840), is thought to be involved in NMDA receptor-dependent forms of long-term depression (LTD). Importantly, the notion that dephosphorylation of these sites contributes to LTD assumes that a significant fraction of GluA1 subunits are basal...
Article
Full-text available
Previous studies have provided strong support for the notion that NMDAR-mediated increases in postsynaptic Ca(2+) have a crucial role in the induction of long-term depression (LTD). This view has recently been challenged, however, by findings suggesting that LTD induction is instead attributable to an ion channel-independent, metabotropic form of N...
Article
Full-text available
Key points  Hypoglossal (XII) motoneurons (MNs) innervate the genioglossus muscle of the tongue, which plays an important role in maintaining upper airway patency and modulating upper airway resistance.  Cyclothiazide (CTZ) is a diuretic, anti-hypertensive, AMPA receptor modulator.  We show that CTZ induces a profound and long-lasting increase in t...
Thesis
Full-text available
Breathing is an essential behavior required to meet metabolic needs. Even short pauses in breathing may be enough to permanently impair or kill a mammal. Breathing is also a complex behavior, requiring the precise coordination of pools of motoneurons (MNs) throughout the brainstem and spinal cord that control upper airway and pump muscles. Breathin...
Article
Full-text available
Since protein kinase-dependent modulation of motoneuronal excitability contributes to adaptive changes in breathing, we hypothesized that cGMP-dependent pathways activating protein kinase G (PKG) modulate motoneuronal inspiratory drive currents and long-term plasticity. In a medullary slice preparation from neonatal rat (postnatal days 0-4) generat...
Conference Paper
Full-text available
The Wideband Gapfiller Satellite (WGS) will provide unprecedented X-band user coverage flexibility with two digitally controlled multibeam phased array antennas. This paper describes the operational concept to show how arrays will provide a significant advance in operational flexibility and communications capability. The design and analysis methods...
Thesis
Full-text available
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1995. Includes bibliographical references (p. 147-149).
Thesis
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1994. Includes bibliographical references (leaf 50).

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