Vladimir E. Trajkovski

Vladimir E. Trajkovski
Ss. Cyril and Methodius University in Skopje · Faculty of Philosophy

M.D., Ph.D

About

112
Publications
20,284
Reads
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406
Citations
Additional affiliations
September 1997 - present
University St. Kiril and Metodij, Faculty of Philosophy
Position
  • Human Genetics
Description
  • Dr. Vladimir Trajkovski is Full Professor on Human Genetics, Medical Aspects of Disability, Physiology and Functional Anatomy, Autism Spectrum Disorders at Institute of Special Education and Rehabilitation
September 1997 - present
Ss. Cyril and Methodius University in Skopje
Position
  • Professor (Full)
Education
October 1995 - March 1999

Publications

Publications (112)
Article
Full-text available
Background and Objective: This study aims to investigate the prevalence of systemic and ophthalmic manifestations in different refractive groups in children and young adults with Down syndrome (DS). Materials and Methods: The study was a population-based, cross-sectional study that included 141 Caucasian children and young adults with DS. They were...
Article
Full-text available
Introduction:This editorial is based on a concise introduction to the basics of open access, describing what it is and showing that it is easy, fast, inexpensive, legal, and a beneficial form of academic publishing. The Internet lets us share perfect copies of our workwith a worldwide audience at virtually no cost. Working in “open access”means: di...
Article
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Introduction: Austism spectrum disorder (ASD) heterogeneity requires these individuals to have functional heterogeneity. Compared to the general population, numerous studies have shown that people with ASD have a lower functional status in performing daily activities and most of them require assistive technology. Methodology: We performed a compara...
Article
Purpose The aim of this study is to determine what changes occur in the health status of people with autism spectrum disorder (ASD) compared to neurotypical controls. Design/methodology/approach The authors performed a comparative analysis of data collected from 72 subjects with ASD and 75 neurotypical controls aged 3–24 years using the Rochester...
Article
Purpose Amid the expanding demand on the autism service delivery system, little knowledge is accumulated regarding access and availability of support and services in the region of Southern and South-Eastern Europe – critical for improvement of individual outcomes, as well as family quality of life. The purpose of this paper is to explore how servic...
Article
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Aim : To determinate the prevalence of congenital infantile esotropia (ETI) in strabismic population with Down syndrome versus strabismic control group from the general Macedonian population. To present subject age, sex distribution, maternal age and spherical equivalent in each of the two analyzed groups. Patients and methods: Population-based ret...
Article
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Ziele: Analyse der Prävalenz der angeborenen-infantilen Esotropie (ETI) in der mazedonische Strabismus Down-Syndrom gruppe versus der Strabismus Kontrollgruppe der allgemeinen Allgemeinbevölkerung sowie Analyse nach Alter, Geschlechtsverteilung, Alter der Mutter und sphärischem Äquivalent in jeder der beiden Gruppen. Patienten und Methoden: Es wurd...
Article
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The difficulty in the area of social skills for persons with Autism Spectrum Disorders (ASD) is particularly visible in the area of sexuality and intimate relationships. Therefore, it is important to create a curriculum including information about sexuality and to address the individual and specific needs of persons with ASD. For this purpose we de...
Article
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The aim of presented study was to explore barriers and facilitators of optimal support for social and developmental outcomes for people with ASD. The survey was based on the semistructured interviews with parents of people with ASD, as well as professionals supporting persons with ASD. Thematic analysis of the data was viewed with regard to positiv...
Article
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Introduction: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that occurs within the first 3 years of life, which is characterised by poor social skills, communication problems and stereotyped patterns of behaviour. Autism is a life-long disorder that has a substantial effect on the individual, their family, and society. Th...
Article
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This randomized controlled study evaluated a computer-based intervention on emotion understanding in 32 children with autism spectrum conditions with and without intellectual disability (ID) aged 7–15 years. The intervention group (n = 16) used the program for 12 h while the control group (n = 16) was not included in any intervention or training be...
Poster
Full-text available
Findings of ESIPP project - post-project poster outlining the project, its findings and impact.
Article
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Introduction: Social participation is a vital construct in inclusive philosophies and practices across communities. People with Autism Spectrum Disorders have been facing autism-related and environmental participation restrictions, placing them at risk of social exclusion and institutionalization. A multinational project has been developed in order...
Article
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Introduction Autism spectrum disorder (ASD) is identified as having a significant impact on family life. Educating parents of children with ASD about the condition benefits both child and family. However, such programmes are typically unavailable in South-east Europe. Aims To address this, the ESIPP project was established to develop and provide pa...
Preprint
Introduction: Autism Spectrum Disorders (ASD) are behaviourally defined syndromes where the etiology and pathophysiology are not very well understood. If the child has been diagnosed with autism, parents already face special behavioural challenges. What makes ASD even more difficult, are the many other medical health issues that often arise in this...
Article
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The aim of this study was to search for predictors of disability among patients treated with hemodialysis. Material and methods: Disability was assessed with self-reports of activities by Katz, Nagi and Rosow-Breslau (R-B) scale in 134 hemodialysis patients in a cross-sectional study. Sociodemographic, clinical, nutritional and dialysis factors wer...
Article
Full-text available
Introduction: Autism Spectrum Disorders (ASD) are behaviourally defined syndromes where the etiology and pathophysiology are not very well understood. If the child has been diagnosed with autism, parents already face special behavioural challenges. What makes ASD even more difficult, are the many other medical health issues that often arise in this...
Preprint
Aim. To examine plasma concentration of IgA, IgM, IgG classes, and IgG1, IgG2, IgG3, and IgG4 subclasses in children with autism. Methods. Infantile autism was diagnosed by the Diagnostic and Statistical Manual for Mental Disorders (DSM)-IV and the International Classification of Diseases (ICD)-10 criteria. Plasma samples were collected from 35 aut...
Article
Full-text available
Context Early detection of developmental problems is critical, and interventions are more effective when they are carried out early in a child's life. In Macedonia, there are only four centers providing early intervention services. Aims In this research, we determined the reliability of the translation and adaptation of Ages and Stages Questionnai...
Preprint
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The number of journals is rapidly rising worldwide. There is public debate about published articles comparing the costs, benefits, and various pros and cons of printed versus electronic full-text journals. The advancement of online journals during recent years has given librarians a powerful new resource to support learning and research. This artic...
Article
Full-text available
The number of journals is rapidly rising worldwide. There is public debate about published articles comparing the costs, benefits, and various pros and cons of printed versus electronic full-text journals. The advancement of online journals during recent years has given librarians a powerful new resource to support learning and research. This artic...
Poster
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This poster was designed for the INSAR 2018 conference in Rotterdam, May 2018, and describes the ESIPP project and findings to date.
Article
Full-text available
Autism spectrum disorder (ASD) is identified as having a significant impact on family life. Educating parents of children with ASD about the condition benefits both child and family. However, such programmes are typically unavailable in South-east Europe. To address this, the ESIPP project developed, provided and evaluated parent education for Croa...
Article
Full-text available
Families living with autism spectrum disorder (ASD) face many challenges, affecting not only the child with ASD and development but also family functioning and quality of life. Parent education (PE) in ASD has been identified as a priority intervention for this group both internationally and nationally. However, though there is a large body of lite...
Article
Full-text available
Families living with autism spectrum disorder (ASD) face many challenges, affecting not only the child with ASD and development but also family functioning and quality of life. Parent education (PE) in ASD has been identified as a priority intervention for this group both internationally and nationally. However, though there is a large body of lite...
Conference Paper
Full-text available
General description: Autism challenges traditional parenting styles, and can make parents feel deskilled and disempowered, especially if little information or support is available to them. Giving accurate information about autism to parents, and teaching them to adapt their parenting using good autism practice has been shown to be effective in impr...
Article
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Parenting children with autism in countries with limited professional and financial resources can be overwhelming. Parent training led by non-governmental organizations may help alleviate some of these burdens. The present pilot study was conducted in the Republic of Macedonia, a country located in Southeastern Europe. The purpose of the study was...
Article
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Introduction and goal: The first edition of the “Journal of Special Education and Rehabilitation” was released for the first time in 1997, and over the past 20 years, 37 issues have been published. In the Journal different kinds of articles are published from several scientific disciplines such as special education and rehabilitation, medicine, ped...
Conference Paper
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Uvod: Autizam je doživotno stanje koje može imati značajan uticaj ne samo na pojedinca s autizmom, nego i na roditelje, braću, sestre i širu porodicu. Na području jugoistočne Evrope psihosocijalna podrška roditeljima dece sa autizmom je slabo razvijena. Ovaj rad se odnosi na trogodišnji ESIPP projekat (septembar 2015.-avgust 2018.) finansiran iz Er...
Conference Paper
Full-text available
Introduction: Epidemiological studies detected that autism spectrum disorders (ASD) are currently raising, and there is a need for early effective interventions to manage the characteristics of the disorder. The evidence suggests that early intervention programs are beneficial for children with autism, often improving developmental functioning and...
Conference Paper
Full-text available
ESIPP – parent education in autism Jasmina Troshanska1, David Preece2, Loizos Symeou3, Katerina Mavrou3, Eleni Teodorou3, Jasmina Stošić4, Jasmina Fray Škrinjar4, Ron Fortuna5, Nefi Charambalos Darden6, Aurelie Baranger7, Sanja Blažević8, Julia Hardcastle9& Vladimir Trajkovski1 1Macedonian Scientific Society for Autism, 2University of Northampton;...
Poster
Full-text available
Autism can challenge traditional parenting styles, causing parents to feel deskilled and disempowered, especially when little information or support is available to them. The provision of accurate information about autism and teaching parents how to adapt their parenting using good autism practice has been shown to be effective in improving persona...
Article
Full-text available
Statistics is mathematical science dealing with the collection, analysis, interpretation, and presentation of masses of numerical data in order to draw relevant conclusions. Statistics is a form of mathematical analysis that uses quantified models, representations and synopses for a given set of experimental data or real-life studies. The students...
Research
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AUTISM SPECTRUM DISORDERS (ASD), NEURODEVELOPMENT, IMMUNOGENETICS, IMMUNE GENES, HLA
Article
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Emerging metrics based on article-level does not exclude traditional metrics based on citations to the journal, but complements them. Article-level metrics (ALMs) provide a wide range of metrics about the uptake of an individual journal article by the scientific community after publication. They include citations, statistics of usage, discussions i...
Article
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Резиме Секоја година сè повеќе семејства се соочуваат со посебни предизвици поврзани со одгледувањето дете со АСН. Стресот е значаен аспект од исполнувањето на улогата на родител, а родителството на дете со АСН значително влијае на стресот што се доживува. Низ литературата се посочува дека нивото на стрес кај родителите е обратнопропорционално со с...
Article
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Во овој предговор е опишан растежот на списанието Дефектолошка теорија и практика во последните 18 години откако започна да се издава. Иако започна како ло-кално и стручно, сепак успеа да се развие во интернационално и научно и да привлече голем број автори од преку 30 држави од светот. Моментно списанието е индексира-но во 65 светски бази на подат...
Conference Paper
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It is critical that speech language pathologists and audiologists understand principles of medical genetics, genetic testing and genetic counseling. Vocal communication mediated by speech and language is a uniquely human trait, and has served an important role in the development of our hearing. Scientists are beginning to uncover the neurogenetic p...
Article
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To investigate whether different types of ocular manifestations are associated with congenital heart disease (CHD) in a large Caucasian population of children and young adults with Down syndrome (DS). Population-based, case-control study which included 185 subjects with DS (mean age 13.2 ± 7.9 years), who reported presence or absence of CHD; DS wit...
Article
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In the present study, we report the fi rst DNA analysis of HLA class I and class II alleles in Macedonian autistic subjects. We have analyzed the HLA-A, -C, -B, DRB1 genotypes of 35 autistic patients, and 98 healthy unrelated Macedonians (control group). HLA DNA typing of class I genes was performed using a Reverse Line Strip method (RLS), and the...
Article
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J Spec Educ Rehab 2004; 5(3-4):43-56.
Article
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The aim of this paper is to analyze the ways of detecting developmental disorders in children in primary health care. We processed data from medical records of 2 634 children examined at Pediatric Dispensary, Military Hospital, Skopje, Republic of Macedonia, during the 2000-2009 period. Children were born between 1990 and 2009. In this retrospectiv...
Article
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Multiple factors infl uence the discrepancy between the prevalence rates of developmental disorders worldwide. In addition to different prevalence rates of developmental disorders, there are differences in terminology and their classifi cation. The purpose of the research was to estimate the prevalence and gender distribution of developmental disor...
Article
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Reading a scholarly journal article is not easy job. General strategy for reading and understanding a scientific paper is to read the material critically. The time that’s available to read scientific literature is becoming increasingly hard to find. Scientists read papers with differing degrees of attention and skepticism. Still, peer-reviewed pape...
Conference Paper
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Introduction: many children and adults with autism spectrum disorder (ASD)
Conference Paper
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oлогија: Истражувајќи и правејќи споредба на квалитетот на од-носот меѓу браќата и сестрите во семејства со дете со аутизам и квалитетот на односот во семејства кај кои нема дете со аутизам, опфативме примерок од 132 испитаника. Податоците беа обработени со стандарден статистички програм SPSS за Windows, применувајќи ги Mann-Whitney U и Wilcoxon te...
Conference Paper
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Introduction: communication is an activity of transfer and exchange of thoughts,
Article
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In scientific writing, plagiarism is regarded as a serious breach of ethics. Plagiarism has different forms but can be categorized into two general distinct categories – plagiarism of ideas and plagiarism of text. The aim of the paper is to address plagiarism at length, to find ways to its disclosure and to make recommendations for its improvement....
Conference Paper
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Objective To investigate Eustachian tube function before and after adenotonsillectomy, adenoidectomy and tonsillectomy. Design Prospective control study. Patients and methods We performed ear, nose, throat examination, and tympanometry in 54 children (28 males and 26 females) before and after adenotonsillectomy, adenoidectomy and tonsillectomy. In...
Article
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In the world of scientific publication, morals are not completely different than in daily life. There are cases of clear research misconduct. If misconduct occurs, it creates a disruption, not only for the scientific community and their institutions, but for all individuals involved. Journals aspire to select, through peer review,the highest qualit...
Article
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The aims of the present population-based, cross-sectional study were to examine the frequency and type of strabismus, refractive errors and nystagmus in children and young adults with Down syndrome (DS) in Macedonia and Croatia. A total of 170 unselected children and young adults with DS aged 1-34 years were examined for ocular findings. The ocular...
Article
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Лицата со Брокина афазија побрзо се соција-лизираат во општеството, поради раниот рехабилитациски третман со примената на логопедска терапија. Во почетокот на болес-та, говорната продукција е напорна, а гово-рот е со променета просодија, болниот се изразува исклучително со именки и работни глаголи, а се користи и со мимика и гестови. Основната цел...
Article
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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills, and eventually even the ability to carry out the simplest tasks. Neurodegeneration is estimated to start 20-30 years before clinical symptoms become apparent. The most common neuropathological feature of AD is the presence of neur...
Article
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The right to work is one of the fundamental human rights in all developed countries around the world. The employment, actually the right to work of persons with disability is the final phase of the long and complex process of their rehabilitation that affects the possibility of their integration in the community.The main objective of this research...
Article
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Persons with autism can experience severe issues during the puberty and adolescence resulting from the changes that occur in their body. People with autism are sexual beings. They have sexual needs and desires as other people. Sexual development is part of the overall development of their personality.The main objective of this research was to prese...
Article
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Autistic disorder is a severe neurodevelopment disorder characterized by a triad of impairments in reciprocal social interaction, verbal and nonverbal communication, and a pattern of repetitive stereotyped activities, behaviours and interests. There are strong lines of evidence to suggest that the immune system plays an important role in the pathog...
Article
Full-text available
Autistic disorder is a severe neurodevelopment disorder characterized by a triad of impairments in reciprocal social interaction, verbal and nonverbal communication, and a pattern of repetitive stereotyped activities, behaviours and interests. There are strong lines of evidence to suggest that the immune system plays an important role in the pathog...
Article
Down's syndrome (DS) is the most common chromosomal anomaly. Numerous ophthalmic features have been reported. The aim of our study was to investigate the incidence of refractive errors in children and young adults with DS in Macedonia. Fifty-six children and young adults with DS, aged 2-28 years, from Macedonia, underwent slit-lamp examination, ocu...
Article
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All children have a need to acquire knowledge about their own body and the way it functions. Also it is neccesary to learn the rules of the society they live in, understand what is accetable, and what is unaccetable behavior. Starting off previous experiences we supposed that in an insufficient measure and in an inadequate way have been provided th...
Article
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Autistic disorder can be associated with mitochondrial dysfunction (MtD). In many cases of autism, there is evidence of mitochondrial dysfunction without the classic features associated with mitochondrial disease. However, routine metabolic screening and mitochondrial functional studies required for the diagnosis of mitochondrial disease are rarely...
Article
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Specific IgA, IgG, and IgE antibodies to food antigens in 35 participants with autistic disorder and 21 of their siblings in the Republic of Macedonia were examined. Statistically significant higher plasma concentration of IgA antibodies against alpha-lactalbumin, beta-lactoglobulin, casein, and gliadin were found in the children with autistic diso...
Article
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Purpose: To analyze the connection between the appearance of strabismus and of epilepsy as an associated condition in children with cerebral palsy, in order to draw a conclusion on the clinical importance of the triad: cerebral palsy, epilepsy and strabismus. Methods: In the prospective random clinical study 2 groups of children were included (49 c...
Article
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Possibilities for intellectual and movement devel­opment of children with disabilities are part of the research that is provided within special education and rehabilitation. But we think that the forgotten component of this research that must have appro­priate principles and methods of its work is the sexual education. Our experience shows that thi...
Article
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Autism is a neurological disorder that limits a person’s ability to function normally. Behavioral abnormalities, social limitations, sensory processing abnormalities, and impaired ability to communicate are the main issues in this multifactorial disorder. The increase in the rate of autism revealed by epidemiological studies implicates the importan...
Article
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Rett syndrome is a sporadic disorder (except for a few familial cases) occuring in 1 in 10.000 to 1 in 23.000 girls worldwide. In 1999, mutations in the methyl-CpG binding protein 2 gene (MECP2) were identified as the primary cause of Rett syndrome. The syndrome’s pathophysiology suggests that early hypofunction of aminergic nurons interferes with...
Article
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People from the”Normal“ population don't have enough knowledge about the problems caused by mental retardation. Very often they have wrong sense and biases about mentally retarded people, considering them as people who suffer from pshychic illness. Mentally retarded people, very often are considered very different from the ”Normal“ population, but...
Conference Paper
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Autism and allied autistic spectrum disorders (ASD) present myriad behavioral, clinical, and biochemical abnormalities. No one method alone is usually effective in treating autism, professionals and families have found that a combination of treatments may be effective in treating symptoms and behaviors that make it hard for individuals with autism...
Article
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Autism is a complex, behaviorally defined, static disorder of the immature brain. Autism is not a disease but a syndrome with multiple nongenetic and genetic causes. Autism is a wide spectrum of developmental disorders characterized by impairments in 3 behavioral domains: 1) social interaction; 2) language, communication, and imaginative play; and...
Article
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Objective- The purpose of this study was to determine the frequency and type of consequences, as well as their presence and distribution in patients with a history of acute bacterial meningitis (ABM) in relation to gender, age, etiology and duration of symptoms prior to admittance to hospital.Methods-The study includes 89 patients with ABM hospital...
Article
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Significant number of the world population is faced with speech disorder problem. Speech disorders can be caused by numerous factors, which can be genetic, congenital or obtained. The knowledge of the etiology of speech disorders is of a great importance, because the early detection and diagnosis are of invaluable significance for successful rehabi...
Article
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Infantile autism is pervasive developmental disorder with abnormal or damaged psychical development manifested after the second or third year of life, with characteristics in the shift of pathological functioning in the sphere of social interactions, in communications with the environment, and with repetitive behavior.The aim of this article is to...