Vjona Cifliku

Université Paris-Saclay · Electrical, Optical And Bio Engineering

Novel trifunctional ligands enable simultaneous bioconjugation (e.g., to antibodies), attachment to nanoparticle surfaces, and photosensitization of Tb ions, affording ultrabright biofunctionalized Tb nanoparticles. These luminescent nanoparticle bioconjugates were successfully implemented in time‐gated FRET spectroscopy and luminescence microscopy...

Lanthanide-doped nanoparticles (LnNPs) have become an important class of fluorophores for advanced biosensing and bioimaging. However, developing bright, stable, and bioconjugated LnNPs remains an important challenge for their translation into functional bioanalytical applications. Here, we present in-situ detection of ligand-receptor binding on ce...

Lanthanide‐doped nanoparticles (LnNPs) have become an important class of fluorophores for advanced biosensing and bioimaging. LnNPs that are photosensitized by surface‐attached antenna ligands can possess exceptional brightness. However, their functional bioconjugation remains an important challenge for their translation into bioanalytical applicat...

Inspiriert von Dalis „Die Beständigkeit der Erinnerung” repräsentieren die drei Uhren im Bild das Prinzip dieser Studie, mit drei zeitlichen optischen Detektionsfenstern, die für eine RGB‐Kodierung (rot, grün, blau) genutzt wurden. Gezeigt sind eine Nanopartikelanordnung (orange Uhr, von Ameisen bedeckt im Original) links unten, ein Mikroskopobjekt...

Inspired by Dali's “The Persistence of Memory” the three clocks in the picture perfectly represent the idea of this study with three temporal optical detection windows that were used for RGB (red, green, blue) encoding. Shown is a single‐nanoparticle assembly (orange clock covered by ants in the original) on the bottom left, a microscope objective...

Fluorescence barcoding based on nanoparticles provides many advantages for multiparameter imaging. However, creating different concentration‐independent codes without mixing various nanoparticles and by using single wavelength excitation and emission for multiplexed cellular imaging is extremely challenging. Here, we report the development of quant...

Fluorescence barcoding based on nanoparticles provides many advantages for multiparameter imaging. However, creating different concentration‐independent codes without mixing various nanoparticles and by using single wavelength excitation and emission for multiplexed cellular imaging is extremely challenging. Here, we report the development of quant...