Vivek K Chaturvedi

Vivek K Chaturvedi
Banaras Hindu University | BHU · Department of Gastroenterology

MS I PhD

About

42
Publications
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465
Citations

Publications

Publications (42)
Chapter
Alzheimer’s disease (AD) is considered one of the most complex neurodegenerative disorders. Amyloid and tau pathology, along with neurofibrillary tangles, are most commonly seen in this disease. Various compounds show promising responses in treating this disease, but they also cause severe side effects. To minimize these side effects, researchers e...
Article
The Indian system of medicine – Ayurveda says “When diet is wrong, medicine is of no use. When diet is correct, medicine is of no use”. In this context, mushroom constitutes one of the major resources for nutraceuticals. Biomolecules of mushrooms have attracted the attention of researchers around the globe due to their proven healthy attributes. Th...
Chapter
Nanoparticle plays a very effective role in the therapeutics of Parkinson’s disease (PD). The blood-brain barrier (BBB) is the main barrier that prevents the efficiency of any therapeutic compound. Nanoparticles overcome this problem by crossing the BBB. Recently many nanoparticles show promising responses in PD. Silver, gold, and many other nanopa...
Chapter
Mushrooms are used not only for culinary purposes, but also for the treatment of various chronic diseases. It shows vital therapeutic activity in several neurodegenerative disorders such as, Alzheimer's and Parkinson's diseases. These diseases are non-communicable as well as age-related. Currently, no drug therapy is available to treat such neurode...
Chapter
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Biofuels are considered as alternative of fossil fuels. Nowadays, conventional fuels like as petrol, diesel, and liquid petroleum gas (LPG) are the major sources of energy. The sources of fossil fuels are limited on the Earth crust and will be finished after a certain period of time. Biofuels like bioethanol, biomethanol, biogas, biohydrogen, and b...
Article
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Agriculture has the most significant contribution in fulfilling the basic human need, sustaining life, and strengthening the economy of any country. To feed the exploding population of the world, there has been a quantum jump in the production of agricultural commodities, which has led to the production of a substantial considerable quantity of agr...
Article
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Synthesis of transition metal oxide nanoparticles is an interesting and expanding research area for biomedical applications due to its biocompatibility. The present study reported the synthesis of manganese oxide nanoparticles via a simple, convenient, low-cost co-precipitation method. The prepared nanoparticles were characterized by X-ray diffract...
Article
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Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this review, we have compiled the information covering limita...
Article
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COVID-19, or the Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic. At the time of writing this (July 28, 2020), more than 17 million people have become affected and 0.7 million people have died across the world. Remdesivir has shown glimpses of insight into how to fight the v...
Article
Mucuna pruriens (Mp) is an annual and perennial legume which belongs to the family Fabaceae having different types of therapeutic activity. Anti-oxidative, anti-inflammatory, anti-epileptic, anti-microbial, etc. are the example of some most common activities of Mp. It is widely utilized as a potent aphrodisiac. The anti-Parkinsonian activity of Mp...
Conference Paper
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In the present study, we have synthesized bimetallic Au/Pt nanoparticles based nanofluid by chemical route method by using microwave irradiation. The synthesized bimetallic nanoparticles have been characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), High resolution transmission electron microscope (HRTEM) and Energy diffraction spectrosco...
Article
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In the current scenario of the fight against cancer Integration of potential elements seems to be the best alternative since it overcomes the weaknesses of individuals and the combination of elements makes them formidable in the fight against the cancer war. Inspired by this objective and trusting our knowledge of paddy straw grown oyster mushroom,...
Article
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SARS-CoV-2, a novel Betacoronavirus, has attracted global attention because of its extremely high infection rate and large number of human deaths. It possesses a positive-sense, single-stranded RNA of ~ 30 kb nucleotides as its genetic material. It is responsible for COVID-19 which has been declared a pandemic by WHO. Having reported for the first...
Chapter
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The catastrophic rise in numeral of individuals suffered from human immunodeficiency virus (HIV)/Acquired immunodeficiency syndrome (AIDS) has necessitated global concern for finding an effective solution to prevent HIV infection. Though the combination antiretroviral therapy (cART) is effective in regards to prevention of HIV proliferation, which...
Preprint
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In recent time peoples become addicted to smartphones that also hamper the social interactions among individuals. It may cause severe anxiety and depressive symptoms betwixt young adolescents. It worsens the loneliness and ultimately affects the wellbeing and social behavior among populations. Thus, the correlation between mobile phone addiction an...
Article
Full-text available
In recent time peoples become addicted to smartphones that also hamper the social interactions among individuals. It may cause severe anxiety and depressive symptoms betwixt young adolescents. It worsens the loneliness and ultimately affects the wellbeing and social behavior among populations. Thus, the correlation between mobile phone addiction an...
Article
Full-text available
The viruses harm brain functioning and cause severe neurological disruption. According to recent studies, the coronavirus exhibits neurotropic characteristics and induces neurological diseases. It also reported that the SARS-CoVs-2 virus could found in the cerebrospinal matter or human brain. Likewise, the exact neuroinvasive mechanisms of viruses...
Article
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Herbal medicines are widely used worldwide and much appreciated because of their fewer side effects and the ability to fight diseases at the root cause. Active 'phyto' ingredients require a scientific approach and a mechanism to distribute components at the target site for better therapeutic results. Nanotechnology, on the other hand, has created n...
Article
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In this paper, the authors explored the role of TREM2 deletion in PS2APP AD mouse model. Authors have compared PS2APP transgenic mice versus PS2APP mice lacking Trem2 (PS2APP;Trem2ko) at different age points. Authors suggest that the toxic activity of Aβ species towards neurons is reduced due to its compaction by TREM2 into dense plaques. Thus, thi...
Chapter
Water is a most crucial and limited resource on the Earth, which has contaminated due to the addition of heavy metals, pathogens, pesticides, and many organic and inorganic substances. Currently, the research has been focused on the sustainable remediation approach for waste reclamation. Therefore, an affordable technology of wastewater treatment c...
Article
Full-text available
Diabetes and obesity are the most frequently found disease worldwide. Several factors are responsible for obesity, i.e., imbalance in energy expenditure, environmental factors, feeding habit, lifestyle, etc., which can also be responsible for type 2 diabetes mellitus. There are several synthetic drugs available to combat these diseases which have s...
Chapter
Diabetes mellitus is one of the serious problem now a days. It is a chronic metabolic disease, caused by autoimmune devastation of insulin producing β-cell of the pancreas. More than 190 million people are affected worldwide by this disorder and the numbers of affected people are predictable to rise about 380 million by the year 2030. Though variou...
Chapter
Lignocelluloses are the most inexhaustible natural compounds in the biosphere, representing around half of the biomass on the planet, with a yearly generation of 10–50 × 10⁹ tons. They are produced as by-products in rural and ranger service from the foods grown, which in turn causes the accumulation of these squanders. This biomass, as squanders, i...
Chapter
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A continuous increase in the genomic data has led to the implementation of computational approaches to store, analyze, annotate, and derive the meaningful interpretation of data. This demands the need for proper databases to submit, store, edit, and update the large-scale data. One of the crucial requirements of biological databases is to provide u...
Chapter
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The remarkable progress made in genomics, proteomics, metabolomics, and microarray gene expression methods has led to exponential rise in the amount of biological data available to scientific community. This huge raw data requires storage, annotation, accurate analysis, and visualization. Hence, there is a growing demand to develop diverse computat...
Article
Hepatocellular carcinoma (HCC) is a cancer which occurs in liver and severity of this cancer makes it the sixth most prevalent cancer and second leading cause of death among all cancers. The load of hepatitis-B virus (HBV) in serum is one of the important risk factors for the HCC. Several other factors also contribute to the HBV associated malignan...
Chapter
Vaccines exhibit great potential to fight against infectious disease. Injected vaccines only pass mucous membranes due to which it generates a poor stimulation in mucosal immune responses. Edible vaccines make contact with the lining of digestive tract by which it activates the mucosal as well as systemic immunity. These properties of edible vaccin...
Article
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment. Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a vital component of a customized way to deal with the malignancy. Nanoparticles are being used as Nanomedicine which participates in diagnosis and treatment of various...
Article
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Medicinal mushrooms are higher fungi with additional nutraceutical attributes having low fat content and a trans-isomer of unsaturated fatty acids along with high fibre content, triterpenes, phenolic compounds, sterols, eritadenine and chitosan. They are considered as the unmatched source of healthy foods and drugs. They have outstanding attractive...
Article
The agricultural sector plays an important role in speeding up the pace of economic development of developing countries in addition to meeting the food security needs of the growing population worldwide. There is not enough food and nutrition available for nearly one billion people worldwide. By 2050, it will be necessary to double the agricultural...
Chapter
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Environmental pollution is becoming one of the major threats around the world because of the release of toxic and hazardous substances from food, pharmaceutical, and other industries as well. These wastes are mainly dumped indiscriminately which ultimately reached water bodies, thereby affecting marine ecosystem. Therefore, effective effluent treat...
Cover Page
Full-text available
From thousands of years ago, Ayurvedic medicines have been used by the saint of our country. It is mentioned in the book "CharakSanhita" written by Maharishi Charak. Mushroom is a nutritious food having medicinal properties. People of China consider it as an important chemical that communicates with the supernatural power of life. Romans resemble m...
Chapter
Full-text available
Stem Cell technology has emerged as an attractive option to inspect and treat the neurodegenerative diseases. Stem cells defined as the cells having the capability to differentiate and the ability to self-renew. Since their discovery research in this area has continued to increase. However, studies indicated that the process of neurogenesis does ta...
Chapter
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Head and neck squamous cell carcinoma (HNSCC) are a diverse group of malignancies which occur in the oral cavity, larynx, oropharynx and hypo pharynx. Head and neck cancer arises from a series of molecular alterations in a progression of skin carcinoma. Different risk factors associated with head and neck cancer includes tobacco chewing, high alcoh...
Chapter
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Cancer stem cells (CSCs) are robust cells which may have acquired characteristics similar to the normal tissue stem cells. CSCs have a set of antigens or markers that define them as a cancer stem cell, which can facilitate isolation of relatively pure populations of these cells from heterogeneous tumors. Various signaling pathways like micro-RNAs a...
Chapter
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Stability of any ecosystem depends on the presence of microbial diversity of that ecosystem. The culturing of bacteria in laboratories is a difficult task due to unidentified nutritional requirement and optimum growth temperature for different bacteria. These two factors are limiting steps for study of bacterial diversity in soil using conventional...
Chapter
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Recently, studies in various types of free radicals have gained attention around the globe as it causes oxidative stress, which may lead to aging and numerous diseases. A balance between free radicals and antioxidants is necessary for appropriate physiological function. At moderate concentrations, free radicals (ROS/RNS) play a significant role as...
Article
Full-text available
Silver nanoparticles (AgNPs) were synthesized using oyster mushroom Pleurotus citrinopileatus extract as a reducing agent and aqueous silver nitrate as the precursor. The AgNPs formation was observed as a color change of the mixture from colorless to dark-brownish. The Transmission Electron Microscopy (TEM) and Energy Dispersive X-Ray spectroscopy...
Article
Full-text available
The oyster mushroom, Pleurotus sajor-caju, was cultivated on different percentages of paddy straw and floral waste. The yield, biological efficiency and moisture content of the mushroom were found to be maximum on 100% Paddy Straw (PS). The proximate compositions of fruiting bodies of mushrooms in terms of protein, total sugar, reducing sugar, non-...
Article
Full-text available
In the present study, we used chemical mutagen ethidium bromide (EtBr) to enhance/induce the production of extracellular laccase enzyme by Pleurotus citrinopileatus. Initially grown on the malt extract agar (MEA) media treated with different concentration of EtBr, the extracellular laccase production was tested in artificial media under static cond...

Questions

Questions (2)
Question
Dear all, I am currently working on the Bioremediation of heavy metal by using fungi. What is the role of fungi in bioremediation? Would you please tell me how fungi absorb harmful heavy metals.
Question
I'm very curious to know the market price of mushrooms. Can you tell me about the market value of medicinal mushrooms present throughout the world?

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Projects

Projects (9)
Project
Accumulation of aberrant proteins and inclusion bodies are hallmarks in most neurodegenerative diseases (NDs). Consequently, they aggregate within neurons leading to toxic effects, overproduction of reactive oxygen species, and oxidative stress. Autophagy is a significant intracellular mechanism that removes damaged organelles and misfolded proteins to maintain cell homeostasis. Excessive or insufficient autophagic activity in neurons leads to altered homeostasis and influences their survival rate, causing neurodegeneration. Autophagic impairment is the most common process observed in several NDs such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), Multiple Sclerosis (MS), etc. Autophagy is a promising field of study with many aspects remaining uninvestigated. Nowadays, autophagy enhancers show a promising response in the effective treatment of neurodegenerative diseases for example AD, PD, HD, and MS. Most importantly herb derived autophagic enhancers have the potential capacity to prevent progressive degeneration in the above-mentioned NDs. Chinese herbal medicine and Indian herbal medicine show powerful autophagic enhancing activity against these NDs. Paeoniflorin, Cinnamic acid, Trehalose, and Resveratrol are some most common herb-derived autophagic enhancers. These enhancers effectively modulate the autophagic pathways in different NDs. The mechanism of action behind the autophagy enhancing the activity of these herbs-derived compounds is in the preliminary stage. Therefore, there will be a strong need to explore the autophagic enhancing activity and the mechanism of action behind this in different NDs. The main aim of this research topic is to attract researchers all across the world working on herbal plants and their derived compounds for NDs (NDs). Herb-derived autophagic enhancer also shows a similar kind of activity with a very minimal side effect as compared to pure chemical compounds. Therefore, an herb-derived autophagic enhancer shows maximum potential as compared to conventional chemical compounds. Researchers all across the world are welcome to explore the herb-derived autophagic enhancer of their indigenous herbal plants. This research topic also welcomes a review article that shows the potential of different herb-derived autophagic enhancers in different NDs. Autophagic processes are severely impaired in some most important NDs such as PD, AD, HD, and MS. Screening of the particular herb-derived compounds that show the maximum impact on different NDs is very crucial. Therefore, this research topic also welcomes the comparable autophagic enhancing activity of different herb-derived compounds. Potential topics to be covered: 1. Screening of the herb-derived compounds having autophagic enhancing activity 2. Comparison of different herb-derived compounds for their autophagic enhancing activity. 3. Role of some common herb-derived compounds for their autophagic enhancing activity in Parkinson’s disease 4. Autophagic enhancing activity of herb-derived compounds in Alzheimer’s disease. 5. Impact of natural autophagic herb-derived enhancer in Huntington’s disease 6. Herb-derived compounds have autophagy enhancing activity and multiple sclerosis 7. Identification of herb derived compounds for their autophagic enhancing activity in Amyotrophic lateral sclerosis 8. Herb-derived compounds have autophagy enhancing activity in Prion disease 9. Herb-derived compounds have autophagy enhancing activity in motor neuron disease 10. Comparison of herb-derived compounds having autophagic enhancing activity in different NDs Keywords: Autophagy, Herbal compounds, mTORC1, TFEB, Neurodegenerative diseases. This research is available in the following link: https://www.frontiersin.org/research-topics/39733/enhancing-autophagy-with-herb-derived-compounds-for-the-treatment-of-neurodegenerative-diseases?utm_source=LOP&utm_medium=Profile&utm_campaign=editorialRolesBrick_FrontiersRTSubmissions_OpenSubmit
Project
Happy to share you that my special issue proposal on the topic entitled "Medicinal plant and Inflammation" has been accepted in the "International journal of Inflammation (Hindawi). We (editoreal team) welcome all researchers to submit their original and review article in this journal. The most striking and interesting thing about this journal is it's citation factor (around 7). This is a newly open journal and will gain impact factor might be around more than 3 when it comes. This is Pubmed and scopus indexed. The deatail about this special issue is attached with this project.