Vittorio Moraschini

• Professor at Universidade Veiga de Almeida

Introduction: Knowing that osteoporosis is a metabolic disease that could decrease dental implant success and survival, the purpose of this review was to gather information on the characteristics of implant osseointegration in animal models of induced osteoporosis. By pointing out the role of some factors that could improve the success rate in the...

To provide an overview of the use of autogenous platelet concentrates (APCs) in periodontal regeneration and to conduct a systematic review (SR) of the treatment outcomes of periodontal intrabony defects by using platelet‐rich fibrin (PRF) compared with other commonly utilized modalities. The eligibility criteria comprised randomized controlled tri...

Objective This scoping review aimed to identify and describe the available evidence on the effect of magnifying devices (loupe or microscope) on the performance of restorative dental preparations. Materials and methods This study was conducted according to the PRISMA-ScR guidelines for scoping reviews and registered on the INPLASY database. An ele...

This clinical report presents a technique to reconstruct extensively resected mandibles using a combination of autologous bone grafts and additive manufacturing techniques. Mandibular defects, often arising from trauma, tumors, or congenital anomalies, can severely impact both function and aesthetics. Conventional reconstruction methods have their...

The present short-term retrospective study evaluated the implant survival rate and peri-implant bone loss around additive-manufactured titanium implants placed in sinuses grafted with Plenum Osshp (Plenum Bioengenharia, Jundia, SP, Brazil) (70HA:30β-TCP) material. A total of 39 implants were inserted after 23 sinus floor elevation procedures in 16...

Statins have demonstrated positive results in alveolar repair after induced osteoporosis in humans and rats. This study aimed to evaluate the osteogenic potential of rosuvastatin (RSV) solution associated with collagen sponge in post-extraction rat alveoli. An experimental study was carried out at the Fluminense Federal University in 30 Wistar rats...

Objective To evaluate the long‐term survival and success rates of implants placed in reconstructed areas using microvascularized or non‐microvascularized extraoral bone grafts. Materials and Methods An electronic search was performed in five databases and in gray literature for articles published until June, 2023. The eligibility criteria comprise...

The early detection of impacted teeth is essential for the prevention of future malocclusions and possible lesions. The aim of this study is to assess the prevalence of impacted teeth and associated pathological lesions. One thousand six hundred and two panoramic radiographs were analyzed for this retrospective study. The prevalence of impacted tee...

This systematic review (SR) aimed to evaluate the antimicrobial potential of different types of platelet‐rich fibrin (PRF) often used in regenerative treatments. An electronic search was performed in four databases and in Gray literature for articles published until January, 2023. The eligibility criteria comprised in vitro studies that evaluated t...

O livro “Diagnóstico e tratamento das complicações em Implantodontia” conta com seis capítulos que abordam objetivamente o diagnóstico e tratamento da maioria das complicações em Implantodontia presentes no fluxo clínico da rotina diária. A temática das complicações, nem sempre bem-vinda, tem sido rechaçada por alguns que desconhecem ou recusam o a...

Prebiotics are substrates selectively utilized by host microorganisms conferring a health benefit. The effects of prebiotics on the gut microbiome of individuals with inflammatory processes need further investigations. The purpose of this study was to evaluate the effects of prebiotics on the gastrointestinal microbiome of individuals with some typ...

Implant therapy is considered a predictable, safe, and reliable rehabilitation method for edentulous patients in most clinical scenarios. Thus, there is a growing trend in the indications for implants, which seems attributable not only to their clinical success but also to arguments such as a more “simplified approach” based on convenience or the b...

Background: Antiresorptive and antiangiogenic medications can cause a serious adverse effect known as medication-related osteonecrosis of the jaw (MRONJ). In recent years, a new trend of research has emerged emphasizing the potential relation of MRONJ and genetic predisposition. Current evidence-based science of this adverse reaction is associated...

Background and objectives: Calcium phosphates have been widely used as bone substitutes, but their properties are limited to osteoconduction. The association of calcium phosphates with osteoinductive bioactive molecules has been used as a strategy in regenerative medicine. Melatonin has been studied due to its cell protection and antioxidant functi...

Background: Zygomatic implants (ZI) have been frequently indicated to rehabilitate patients with extensive atrophies in alternatives to major bone reconstructions. It can be installed inside the maxillary sinus, called instrasinus zygomatic implant (IZI) or outside the maxillary sinus (EZI), depending on the surgery technique. Objective: To eval...

This systematic review evaluated the features of the progression of experimentally induced gingivitis and peri-implant mucositis in humans. Included were studies that evaluated clinical , immunological, or microbiological responses between experimentally induced gingi-vitis and peri-implant mucositis in periodontally healthy patients. A total of 88...

The aim of this study was to assess the reporting quality of abstracts in systematic reviews (SRs) related to implant dentistry and to assess the possible factors associated with the reporting quality. Abstracts of SRs in the field of implant dentistry, published in the last 5 years, were searched. The reporting quality was assessed and scored usin...

Lasers are increasingly utilized in the non-surgical treatment of periodontal disease. The aim of the present systematic review with meta-analysis was to investigate the combination use of Nd:YAG and Er:YAG laser therapy in the treatment of severe periodontitis. A systematic review of the literature including searches in PubMed/Medline, Cochrane Li...

Peri‐implantitis is characterized by nonreversible and progressive loss of supporting bone and is associated with bleeding and/or suppuration on probing. Peri‐implant disease is considered as the main etiologic factor related to implant failure. Peri‐implant disease has a pathogenesis similar to that of periodontal disease, both being triggered by...

Purpose: The aim of the present systematic review with meta-analysis was to investigate the clinical effectiveness of EMD (enamel matrix derivative) using a minimally invasive surgical technique (MIST) or flapless approach for the treatment of severe periodontal probing depths. Materials and methods: A systematic review of the literature includi...

Osseodensification is a new method of bone instrumentation for dental implant placement that preserves bulk bone and increases primary implant stability, and may accelerate the implant rehabilitation treatment period and provide higher success and survival rates than conventional methods. The aim of this retrospective study was to evaluate and disc...

Objectives: To investigate the long-term prevalence of taste disorder (TD) and olfactory disorder (OD) and associated risk factors in the non-hospitalized southeastern Brazil population of COVID-19 patients. Methods: This cross-sectional open survey evaluated possible long-term OD and TD in non-hospitalized patients who had been diagnosed with C...

Background: Osteonecrosis of the jaw (ONJ) is a condition affecting patients exposed to medications used to treat benign and malignant conditions of bone tissue. Many studies have highlighted that ONJ is a severe condition, which is very challenging to manage, especially in individuals with oncologic disease. The aim of this umbrella review is to a...

Purpose: To investigate the effect of platelet-rich fibrin on bone formation by investigating its use in guided bone regeneration, sinus elevation and implant therapy. Materials and methods: This systematic review and meta-analysis were conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analys...

Evidence shows that an increased width and thickness of the keratinized mucosa favours peri-implant health. The aim of this network meta-analysis was to compare the clinical effects of alternative biomaterials for peri-implant soft tissue phenotype modification (PSPM) in patients with dental implants when compared to autologous tissue grafts. An el...

Background At present the clinical efficacy of single (S) versus multiple (M) applications of antimicrobial photodynamic therapy (aPDT) is controversially discussed. Aim To systematically evaluate the clinical efficacy of adjunctive S and M applications of aPDT to subgingival debridement (SD) in the treatment of residual periodontal pockets. Meth...

This systematic review aimed to review the literature on the coronectomy technique and evaluate the incidence of success and complications as a surgical approach for inferior third molars. Online databases were searched for data on the frequency of inferior alveolar nerve damage, lingual nerve damage, root migration, pain, infection, dry socket, an...

Purpose: To investigate the use of platelet-rich fibrin for alveolar ridge preservation compared to natural healing, bone graft material and platelet-rich fibrin in combination with bone graft material. Materials and methods: The present systematic review was conducted and reported according to the Preferred Reporting Items for Systematic Review...

Objectives This study aims to compare the treatment outcomes of periodontal intrabony defects by using platelet-rich fibrin (PRF) with other commonly utilized modalities. Materials and methods The eligibility criteria comprised randomized controlled trials (RCTs) comparing the clinical outcomes of PRF with that of other modalities. Studies were cl...

Objective A systematic review (SR) was conducted to answer the following focused question based on PICO strategy: In patients who were submitted to harvesting palatal free gingival graft, could platelet-rich fibrin (PRF) application in comparison with another method improve the healing, pain, and control of postoperative bleeding in the palatal are...

Objective To investigate the efficacy of platelet-rich fibrin (PRF) for the socket healing after removal of mandibular third molars when compared to natural wound healing. Methods This systematic review and meta-analysis were conducted according to PRISMA guidelines. The eligibility criteria comprised randomized controlled trials (RCTs) comparing...

Parameters such as the correct 3-dimensional positioning and the quality of peri-implant soft tissues are fundamental to the success of implant-supported restorations. Digital planning and guided surgery techniques can make the implant placement more accurate, and modifying the periodontal phenotype is often fundamental to increasing esthetics and...

This systematic review (SR) aimed to evaluate implant survival rate, marginal bone loss (MBL), and biological/prosthetic complications of extra-short 4 mm dental implants. An electronic search without language or date restrictions was performed in five databases and in gray literature for articles published until August 2020. Prospective cohort stu...

Objectives This study aimed to evaluate dimensional changes, level of soft tissue healing, and pain/discomfort perception in post‐extraction sockets filling with 1.2% simvastatin (SIM) gel covered with polypropylene membranes (PPPM). Material and methods Twenty‐six post‐extraction sockets of posterior teeth were randomly allocated in two groups: 1...

Making an intraoral digital scan of the emergence profile is a clinical challenge. The peri-implant soft tissue collapses after removal of an interim prosthesis, which compromises the correct design of a definitive implant-supported prosthesis. Although techniques are available for digitally reducing such a distortion, achieving a correct alignment...

This first clinical chapter focuses on the use of PRF for root cover-age procedures in comparison to other treatment modalities. In total, 17 RCTs are presented comparing the use of coronally advanced flap (CAF) with and without PRF versus connective tissue graft (CTG), enamel matrix derivative (EMD; Emdogain), and amniotic membrane. Reports on the...

Over the past 20 years, an increasing trend has been observed in periodontology whereby the resolution(/regeneration) of intra-bony and furcation defects has been accomplished by means of biologic agents and growth factors. Enamel matrix derivative (Emdogain) and (rhPDGF have both been successfully utilized in regenerative periodontology due to the...

Atrophic maxilla rehabilitation through dental implants is always a challenging procedure. However, alternative approaches such as guided surgery and the installation of short implants are progressively supplanting more invasive bone regeneration procedures. A V-4 technique described in 2016 facilitates the installation of dental implants in patien...

Objectives This study aimed to conduct a network comparison of the clinical effect of connective tissue graft (CTG) substitutes on the treatment of gingival recessions using coronally advanced flap.Materials and methodsAn electronic search without language or dates restrictions was performed in five databases and in Grey literature for articles pub...

Making an intraoral digital scan for fixed mandibular implant-supported complete-arch prostheses is a clinical challenge. The absence of references in the mandibular arch for precise scan alignment may complicate the correct digital design of the prosthesis framework. This article presents a straightforward method that allows a completely digital a...

This overview aimed to evaluate the methods, quality, and outcomes of systematic reviews (SRs) conducted to investigate the effects of platelet-rich fibrin (PRF) in dental sockets on promoting bone regeneration and soft tissue healing and diminishing the incidence of pain, swelling, trismus, and alveolar osteitis after tooth extraction. An electron...

Objectives The aim of this systematic review and meta-analysis was to compare the use of platelet-rich fibrin (PRF) with other commonly utilized treatment modalities for root coverage procedures.Materials and methodsThe eligibility criteria comprised randomized controlled trials (RCTs) comparing the performance of PRF with that of other modalities...

Objectives This study aimed to evaluate the clinical effects of xenogeneic collagen matrix (XCM) in augmenting keratinized mucosa width (KMW) around dental implants.Materials and methodsArticles that were published before or during April 2020 were electronically searched in four databases without any date or language restrictions and manually searc...

ObjectiveA systematic review and meta-analysis was thus conducted to answer the following focused question based on PICO strategy: Is there any 3D matrix biomaterial used for root coverage of human Miller class I and II defects equivalent with the connective tissue graft in localized defects of at least 2 mm and 3 mm?Material and methodsThe search...

Background Although several therapies are proposed for medication‐related osteonecrosis of the jaw (MRONJ), to date there is no consensus or treatment protocol for MRONJ. This overview aims to summarize the available evidence on the management and outcomes of MRONJ. Methods An electronic search without language or date restrictions occurred in fiv...

Objective This systematic review (SR) aimed at assessing the adjunctive clinical effect of ozone therapy (OT) on nonsurgical periodontal treatment.Materials and methodsArticles published prior to September 2019 were electronically searched in four databases without any other date or language restrictions and manually searched in regular journals an...

Several studies have aimed to develop alternative therapeutic biomaterials for bone repair. The purpose of this systematic review was to evaluate how statins carried by calcium phosphate affect the formation and regeneration of bone tissue in animal models when compared to other biomaterials or spontaneous healing. This systematic review followed t...

This study aimed to evaluate the clinical effect of leukocyte- and platelet-rich fibrin (L-PRF) to improve epithelialization and decrease postoperative pain in post-extraction sockets. Thirty two participants requiring extractions of posterior teeth were randomized into two groups: 1) extractions and socket filling with L-PRF membrane (test group)...

Background: Although widely used, the potential for immunological sensitization of allogeneic bone grafts is still controversial in the literature. This systematic review aimed to evaluate the immune response of allogeneic bone grafts procedures in humans. Methods: An electronic search without language or date restrictions occurred in four datab...

Tumour necrosis factor-α (TNF-α) inhibitors are increasingly being used as immunomodulators to manage inflammatory conditions such as rheumatoid arthritis and Crohn's disease. Reported serious side effects include an increased incidence of lymphoma and greater susceptibility to infections such as tuberculosis. The aim of this systematic review was...

A randomized controlled trial was performed to evaluate and compare the changes in implant stability quotient (ISQ) of implants of the same brand, design, length, and diameter but with two different surface treatments, placed in the posterior mandible: sandblasted and acid-etched (SAE) and chemically modified SAE (hydrophilic). Twenty implants of t...

Objective: The aim of this systematic review (SR) was to evaluate the effects of xenogenic collagen matrix (XCM) on the outcomes of clinical treatments of patients with Miller class-I or -II gingival recessions. Materials and methods: Articles that were published before March 2018 were electronically searched in four databases without any date or l...

Objectives: Our aim was to conduct a systematic review (SR) of the literature assessing the role of human biomarkers in the diagnosis or prognostication of medication-related osteonecrosis of the jaws (MRONJ). Study design: An electronic search without date or language restriction was carried out in PubMed/MEDLINE, the Cochrane Central Register...

The aim of this randomized clinical trial was to evaluate the newly formed tissues in post-extraction sockets and to compare ridge dimensional changes with and without the use of a dense polytetrafluoroethylene membrane (d-PTFE). Twenty human extraction sockets (lower molars and premolars) received either an intentionally exposed d-PTFE membrane (t...

The purpose of this overview was to assess the methods, quality, and outcomes of systematic reviews conducted to evaluate the impact of bisphosphonates on dental implants and the risk of developing bisphosphonate-related osteonecrosis of the jaw after dental implant surgery. An electronic search without date or language restriction was performed in...

Objective: The aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity. Materials and methods: An electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-sear...

The purpose of this systematic review was to evaluate the quantitative histomorphometric outcomes of animal studies investigating statins as a pro-osteogenic agent to enhance the osseointegration of dental implants. Some animal studies have suggested a beneficial action of statins on bone tissue. Electronic and manual literature searches, without d...

Objectives The Sjögren’s syndrome (SS) is a chronic autoimmune disease that affects salivation and consequently the health of oral tissues. The aim of this systematic review was to investigate the implant survival rate, marginal bone loss (MBL) and biological complications of dental implants in SS patients. Materials and methods Eligibility criter...

Background: The aim of this systematic review (SR) is to evaluate the association between asthma and periodontal parameters. Methods: An electronic search without date or language restrictions was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until May 2017. In addition, manual search and in the grey literature were also conducted...

Calcium phosphate (CP) has been used as biomaterial to regenerate bone defects. In order to improve its biological properties, substitutions in the calcium phosphate chemical structure have been investigated. Zinc has stimulatory effects on in vitro and in vivo bone formation and an inhibitory effect on in vitro osteoclastic bone resorption. The ai...

Background: The aim of this systematic review is to evaluate the association between asthma and periodontal disease. Methods: An electronic search without date or language restrictions was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until May 2016. In addition, manual search and in the grey literature were also conducted. The se...

Invasive multiple cervical root resorptions after vital tooth bleaching is a rare condition. The aim of this article is to present a case of multiple external cervical root resorptions (ECRR) after a misguided home whitening treatment. A 34-year-old male patient presented with slight sensitivity and mobility in several teeth. Despite the manufactur...

The aim of this overview was to assess the methods, quality, and outcomes of systematic reviews conducted to evaluate the importance of keratinized mucosa (KM) for the maintenance of peri-implant tissue health in humans. An electronic search was conducted without date or language restriction using the MEDLINE/PubMed, Cochrane Library, Web of Scienc...

The present study aimed to conduct a systematic review and meta-analysis on the effectiveness of maxillary sinus floor elevation and immediate implant installation without the use of grafting material. An electronic search without date or language restriction was performed in PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Sc...

The aim of this study was to investigate the hypothesis that there is no difference in implant failure rate or marginal bone loss between type 1 or 2 diabetes subjects and non-diabetic subjects. An electronic search was conducted, without restrictions on date or language, in the PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of...

The aim of this overview was to evaluate and compare the quality of systematic reviews, with or without meta-analysis, that have evaluated studies on techniques or biomaterials used for the preservation of alveolar sockets post tooth extraction in humans. An electronic search was conducted without date restrictions using the Medline/PubMed, Cochran...

Objective: This systematic review evaluated survival rates, marginal bone loss (MBL), and complications of using 2 to 4 implants to support full-arch fixed prostheses in the mandible. Materials and methods: An electronic search was performed in PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials to identify relevant ar...

Background: The aim of this systematic review was to evaluate the effects of platelet-rich fibrin (PRF) membranes on the outcomes of clinical treatments in patients with gingival recession. Methods: Articles that were published before June 2015 were electronically searched in four databases without any date or language restrictions and manually...

The aim of this meta-analysis was to analyse the effectiveness of submucosal injection of dexamethasone to control the postoperative signs and symptoms resulting from impacted third molar surgery. An electronic search was conducted, without restriction on date or language, in the PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, and W...

The purpose of this review was to test the null hypothesis of no difference in marginal bone loss and implant failure rates between smokers and non-smokers with respect to the follow-up period. An extensive electronic search was performed in PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials to identify relevant articles...

The purpose of this meta-analysis was to compare implant survival, marginal bone loss, and complications between immediate and conventional loading of single implants installed in the posterior mandible. An extensive electronic search was performed of PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials to identify relevan...

The aim of the present review was to evaluate by means of a systematic review and meta-analysis the hypothesis of no difference in failure rates between amalgam and composite resin posterior restorations. Randomized controlled trials, controlled clinical trials and prospective and retrospective cohort studies were included in this review. The eligi...

This systematic review evaluated the implant survival rate, changes in marginal bone level, and complications associated with guided surgery for the treatment of fully edentulous patients followed up for longer than 1 year. A comprehensive literature search was conducted in MEDLINE/PubMed and the Cochrane Central Register of Controlled Trials (CENT...

The current literature was reviewed to evaluate the effect of autologous plasma concentrates on the preservation of extraction sockets. A comprehensive literature search was performed from October 2013 to February 2014 in the MEDLINE/PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) databases. Four studies, published between the y...

The aim of this systematic review was to evaluate the survival and success rates of osseointegrated implants determined in longitudinal studies that conducted a follow-up of at least 10 years. A broad electronic search was conducted in MEDLINE/PubMed and the Cochrane Central Register of Controlled Trials (CENTRAL) for relevant publications in index...