Vitor De Salles Painelli

Universidade Paulista · Institute of Health Sciences

Previous systematic reviews have confirmed that carbohydrate (CHO) mouth rinse may boost physical exercise performance, despite some methodological aspects likely affecting its ergogenic effect. In this review, we discussed if the exercise mode, pre-exercise fasting status, CHO solutions concentration, CHO solutions temperature, mouth rinse duratio...

Background: We aimed to investigate the isolated effect of tele-exercises (TE) and its combined effect with nutritional coaching (NC) on health-related parameters of overweight and obese individuals. Methods: Forty-one overweight (body mass index ≥25 kg·m2) and obese (body mass index ≥30 kg·m2) women were randomly assigned to the experimental group...

The long-standing caffeine habituation paradigm was never investigated in strength endurance and jumping exercise performance through a straightforward methodology. The authors examined if habitual caffeine consumption would influence the caffeine ergogenic effects on strength endurance and jumping performance as well as perceptual responses. Thirt...

Detrimental mental fatigue effects on exercise performance have been documented in constant workload and time trial exercises, but effects on a maximal incremental test (MIT) remain poorly investigated. Mental fatigue-reduced exercise performance is related to an increased effort sensation, likely due to a reduced prefrontal cortex (PFC) activation...

Teixeira, EL, Ugrinowitsch, C, de Salles Painelli, V, Silva-Batista, C, Aihara, AY, Cardoso, FN, Roschel, H, and Tricoli, V. Blood flow restriction does not promote additional effects on muscle adaptations when combined with high-load resistance training regardless of blood flow restriction protocol. J Strength Cond Res 35(5): 1194-1200, 2021-The a...

Caffeine has been shown to increase anaerobic energy contribution during short-duration cycling time-trials (TT) though no information exists on whether caffeine alters energy contribution during more prolonged, aerobic type TTs. The aim of this study was to determine the effects of caffeine supplementation on longer and predominantly aerobic exerc...

Caffeine has been shown to increase anaerobic energy contribution during short-duration cycling time-trials (TT) though no information exists on whether caffeine alters energy contribution during more prolonged, aerobic type TTs. The aim of this study was to determine the effects of caffeine supplementation on longer and predominantly aerobic exerc...

Teixeira, EL, Painelli, VdS, Schoenfeld, BJ, Silva-Batista, C, Longo, AR, Aihara, AY, Cardoso, FN, Peres, BdA, and Tricoli, V. Perceptual and neuromuscular responses adapt similarly between high-load resistance training and low-load resistance training with blood flow restriction. J Strength Cond Res XX(X): 000-000, 2020-This study compared the eff...

Detrimental mental fatigue effects on exercise performance have been documented in constant workload and time trial exercises, but effects on a maximal incremental test (MIT) remain poorly investigated. Mental fatigue-reduced exercise performance is related to an increased effort sensation, likely due to a reduced prefrontal cortex (PFC) activation...

Existe um crescente interesse na eficácia terapêutica da dieta cetogênica, dada a hipótese de que a restrição de carboidratos (CHO) favoreceria uma menor atividade de células tumorais. Mesmo assim, tais dietas continuam sendo um tema controverso na área de oncologia. Assim, este trabalho tem como objetivo sumarizar os estudos que já investigaram os...

Longo, AR, Silva-Batista, C, Pedroso, K, de Salles Painelli, V, Lasevicius, T, Schoenfeld, BJ, Aihara, AY, de Almeida Peres, B, Tricoli, V, and Teixeira, EL. Volume load rather than resting interval influences muscle hypertrophy during high-intensity resistance training. J Strength Cond Res 36(6): 1554-1559, 2022-Interset rest interval has been pro...

Carnosine is a dipeptide abundantly found in human skeletal muscle, cardiac muscle and neuronal cells having numerous properties that confers performance enhancing effects, as well as a wide-range of potential therapeutic applications. A reliable and valid method for tissue carnosine quantification is crucial for advancing the knowledge on biologic...

Brandão, L, de Salles Painelli, V, Lasevicius, T, Silva-Batista, C, Brendon, H, Schoenfeld, BJ, Aihara, AY, Cardoso, FN, de Almeida Peres, B, and Teixeira, EL. Varying the order of combinations of single- and multi-joint exercises differentially affects resistance training adaptations. J Strength Cond Res XX(X): 000-000, 2020-Our study aimed to com...

Purpose To investigate the effects of chronic beta-alanine (BA) supplementation on muscle taurine content, blood clinical markers and sensory side-effects. Methods Twenty-five healthy male participants (age 27 ± 4 years, height 1.75 ± 0.09 m, body mass 78.9 ± 11.7 kg) were supplemented with 6.4 g day⁻¹ of sustained-release BA (N = 16; CarnoSyn™, N...

Quando executado cronicamente, o exercício aeróbio promove inúmeros benefícios sobre o desempenho físico e a saúde. No entanto, sessões agudas de exercício aeróbio provocam a produção de Radicais Livres, cujo acúmulo está associado a diversos efeitos prejudiciais sobre a célula, e em última instância, sobre a saúde. Apesar da existência de defesas...

Background: Stretching may promote detrimental effects on power output and maximal strength, but its direct effect on strength endurance remains unclear, as well as the influence of stretching duration. Objective: we aimed to evaluate the direct effect of static stretching of quadriceps muscle, as well as the stretching duration, on the strength en...

We sought to determine if early increases in cross‐sectional area (CSA) of different muscles composing the quadriceps with low‐load resistance training with blood flow restriction (LL‐BFR) were mainly driven by muscle hypertrophy or by edema‐induced swelling. We also compared these changes to those promoted by high‐load resistance training (HL‐RT)....

Purpose: High-intensity exercise is limited by muscle acidosis, among other factors. Supplementation with buffering agents can delay the onset of muscular fatigue and improve performance (Saunders et al., 2017, Heibel et al., 2018). These include supplements that can increase the extracellular buffering capacity (e.g., sodium bicarbonate, which inc...

β-Alanine supplementation is one of the world's most commonly used sports supplements, and its use as a nutritional strategy in other populations is ever-increasing, due to evidence of pleiotropic ergogenic and therapeutic benefits. Despite its widespread use, there is only limited understanding of potential adverse effects. To address this, a syst...

Lenzi, JL, Teixeira, EL, de Jesus, G, Schoenfeld, BJ, and de Salles Painelli, V. Dietary strategies of modern bodybuilders during different phases of the competitive cycle. J Strength Cond Res 35(9): 2546-2551, 2021-Bodybuilders have used a wide array of nutritional strategies over the years. However, most information on the topic is anecdotal, wit...

Teixeira, EL, de Salles Painelli, V, Silva-Batista, C, de Souza Barros, T, Longo, AR, Lasevicius, T, Schoenfeld, BJ, Aihara, AY, and de Almeida Peres, B. Blood flow restriction does not attenuate short-term detraining-induced muscle size and strength losses after resistance training with blood flow restriction. J Strength Cond Res 35(8): 2082-2088,...

Bertolaccini, AL, da Silva, AA, Teixeira, EL, Schoenfeld, BJ, and de Salles Painelli, V. Does the expectancy on the static stretching effect interfere with strength-endurance performance? J Strength Cond Res 35(9): 2439-2443, 2021-Static stretching (SS) may interfere with strength performance. Such interference, however, may be partially attributed...

Proton magnetic resonance spectroscopy (1H-MRS) has been used as a non-invasive alternative to quantify carnosine in human muscle. It is unclear whether 1H-MRS is a valid and reliable method. 1H-MRS validity and reliability was examined in a series of in vitro and in vivo studies. In the in vitro study, phantoms containing different concentrations...

β-Alanine (BA) supplementation may be ergogenic during high-intensity exercise, primarily due to the buffering of hydrogen cations, although the effects of beta-alanine supplementation on strength endurance are equivocal. The aim of the study was to determine the effects of 4 weeks of beta-alanine supplementation on skeletal muscle endurance using...

The effects of β-alanine (BA) and sodium bicarbonate (SB) on energy metabolism during work-matched high-intensity exercise and cycling time-trial performance were examined in 71 male cyclists. They were randomised to receive BA + placebo (BA, n = 18), placebo + SB (SB, n = 17), BA + SB (BASB, n = 19), or placebo + placebo (PLA, n = 18). BA was supp...

Purpose: Cross-sectional studies suggest that training can increase muscle carnosine (MCarn), although longitudinal studies have failed to confirm this. A lack of control for dietary β-alanine intake or muscle fibre type shifting may have hampered their conclusions. The purpose of the present study was to investigate the effects of high-intensity...

O aumento da temperatura interna (Ti) é considerado importante causa da fadiga durante exercícios prolongados realizados no calor. Dentre as estratégias empregadas para atenuá-la, a reposição hídrica é a que mais se destaca por sua praticidade e baixo custo. Por outro lado, pouco sabe-se a respeito da influência que a temperatura dos repositores hí...

Objective: To investigate the influence of habitual caffeine intake on exercise performance to acute caffeine supplementation. Methods: A double-blind, crossover, counterbalanced study was performed. Forty endurance-trained cyclists were allocated into tertiles according to their daily caffeine intake: low (58 ± 29 mg(.)d(-1)), moderate (143 ± 2...

The aim of this study was to comprehensively determine the reliability of performance and physiological measurements during a simulated work-based cycling time-trial (TT), without (Part A) and with (Part B) a familiarisation session using a battery of statistical tests. Fifty recreationally-trained cyclists performed a work-based cycling TT test on...

Introduction: Skeletal muscle carnosine content can be increased through β-alanine supplementation, but the maximum increase achievable with supplementation is unknown. No study has investigated the effects of prolonged supplementation on carnosine-related genes or exercise capacity. Purpose: To investigate the effects of 24-weeks of β-alanine s...

Since there is conflicting data on the buffering and ergogenic properties of calcium lactate (CL), we investigated the effect of chronic CL supplementation on blood pH, bicarbonate, and high-intensity intermittent exercise performance. Sodium bicarbonate (SB) was used as a positive control. Eighteen athletes participated in this double-blind, place...

We investigated the effects of supplement identification on exercise performance with caffeine supplementation. Forty-two trained cyclists (age 37 ± 8 years, body mass [BM] 74.3 ± 8.4 kg, height 1.76 ± 0.06 m, maximum oxygen uptake 50.0 ± 6.8 mL/kg/min) performed a ~30 min cycling time-trial 1 h following either 6 mg/kgBM caffeine (CAF) or placebo...

Sodium citrate (SCit) supplementation has been studied for several years as a strategy to reduce the muscle fatigue induced by H? ion accumulation within the skeletal muscle during high-intensity, short-duration exercise. Several investigations have been published on this matter, and appear to indicate that SCit is not effective as an ergogenic aid...

Objectives: In official judo competitions, athletes usually engage in 5-7 matches in the same day, performing numerous high-intensity efforts interspersed by short recovery intervals. Thus, glycolytic demand in judo is high and acidosis may limit performance. Carnosine is a relevant intracellular acid buffer whose content is increased with beta-al...

To compare the reliability of the three high-intensity exercise protocols: the CCT110%, repeated upper-body Wingate test and repeated lower-body Wingate test. Methods: seventy individuals (age 27 ± 6 y, body mass 78.2 ± 12.2 kg, height 1.79 ± 0.08 m) performed the anaerobic tests in two different sessions. For the CCT110% TWD was not different betw...

The national cycling calendar in Brazil is extensive with numerous regional and state competitions on a weekly basis. Furthermore, several teams now compete in national, continental and international races throughout the calendar year. In light of Brazil’s increasing interest and progression in the world of cycling, we aimed to determine the charac...

Beta-alanine supplementation over 4-10 weeks has consistently been shown to improve high-intensity cycling capacity (CCT110%) by 12-16%(Hill et al., 2007; Sale et al., 2011; Danaher et al., 2014). However, there is no evidence as to whether further improvements occur when supplementation is prolonged. PURPOSE: To determine the effects of 24 weeks o...

Objectives: Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. We determined the consistency of metabolic and exercise responses following r...

Intramuscular acidosis is a contributing factor to fatigue during high-intensity exercise. Many nutritional strategies aiming to increase intra- and extracellular buffering capacity have been investigated. Among these, supplementation of beta-alanine (~3-6.4 g/day for 4 weeks or longer), the rate-limiting factor to the intramuscular synthesis of ca...

Currently, there has been new expectations in studying strategies with the potential to mitigate the skeletal muscle atrophy that characterizes conditions such as aging, disuse, cancer, and the use of certain medications. Among them, amino acid leucine has received special attention due to its potential to stimulate specific pathways of protein syn...

Objectives: Two independent studies were conducted to examine the effects of 28 d of beta-alanine supplementation at 6.4 g d(-1) on brain homocarnosine/carnosine signal in omnivores and vegetarians (Study 1) and on cognitive function before and after exercise in trained cyclists (Study 2). Methods: In Study 1, seven healthy vegetarians (3 women...

The current investigation aimed to develop a valid specific field test to evaluate anaerobic physical performance in Aerobic Gymnastics athletes. We first designed the Specific Aerobic Gymnast Anaerobic Test (SAGAT), which included gymnastics-specific elements performed in maximal repeated sprint fashion, with a total duration of 80-90 s. In order...

RESUMO Fatores que melhoram as adaptações ao treino de força, especialmente os nutricionais, têm sido alvo de interesse de praticantes de treino de força. Devido aos já conhecidos mecanismos de ação da cafeína, pesquisas vêm sendo desenvolvidas com o intuito de investigar o potencial ergogênico da cafeína sobre o desempenho de força. Tais estudos,...

LACTATO: DE CAUSA DA FADIGA A SUPLEMENTO ERGOGÊNICO? RESUMO: Durante anos, pesquisadores inseridos na área de fisiologia do exercício apontaram para o lactato como o principal causador da fadiga durante exercícios de alta intensidade. Hoje, por outro lado, já existem diversos estudos demonstrando que o lactato per se não possui qualquer efeito sob...

Purpose: To investigate the effect of creatine (CR) supplementation on the acute interference induced by aerobic exercise on subsequent maximum dynamic strength (1RM) and strength endurance (SE, total number of repetitions) performance. Methods: Thirty-two recreationally strength-trained men were submitted to a graded exercise test to determine...

Recent investigations have suggested that highly trained athletes may be less responsive to the ergogenic effects of β-alanine (BA) supplementation than recreationally active individuals due to their elevated muscle buffering capacity. We investigated whether training status influences the effect of BA on repeated Wingate performance. Forty young m...

It has been suggested that the abrupt liposuction-induced decrease in adipose tissue could affect adipokine secretion pattern. We hypothesized that exercise training could positively impact adipokine metabolism following liposuction. The aim of this study was to investigate the effects of liposuction on inflammation-related adipokines in women who...

The present cross-sectional study aimed to examine the influence of diet on brain creatine (Cr) content by comparing vegetarians with omnivores. Brain Cr content in the posterior cingulate cortex was assessed by proton magnetic resonance spectroscopy (1H-MRS). Dietary Cr intake was assessed by 3 d food recalls. Vegetarians had lower dietary Cr inta...

We investigated the effects of low- and high-dose calcium lactate supplementation on blood pH and bicarbonate (Study A) and on repeated high-intensity performance (Study B). In Study A, ten young, physically active men (age: 24 ± 2.5 years; weight: 79.2 ± 9.45 kg; height: 1.79 ± 0.06 m) were assigned to acutely receive three different treatments, i...

The aim of this study was to determine the effects of creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet. A randomized, double-blind, placebo-controlled trial was performed. The participants were randomly allocated to receive either creatine (20 g/d for 5 d followed by 5 g/d throughout the tr...

We investigated the effect of beta-alanine (BA) alone (study A) and in combination with sodium bicarbonate (SB) (study B) on 100- and 200-m swimming performance. In study A, 16 swimmers were assigned to receive either BA (3.2 g·day(-1) for 1 week and 6.4 g·day(-1) for 4 weeks) or placebo (PL; dextrose). At baseline and after 5 weeks of supplementat...

We examined the isolated and combined effects of beta-alanine (BA) and sodium bicarbonate (SB) on high-intensity intermittent upper-body performance in judo and jiu-jitsu competitors. 37 athletes were assigned to one of four groups: (1) placebo (PL)+PL; (2) BA+PL; (3) PL+SB or (4) BA+SB. BA or dextrose (placebo) (6.4 g day(-1)) was ingested for 4 w...

Cure rates of youth with Acute Lymphoblastic Leukemia (ALL) have increased in the past decades, but survivor's quality of life and physical fitness has become a growing concern. Although previous reports showed that resistance training is feasible and effective, we hypothesized that a more intense exercise program would also be feasible, but more b...

We examined whether creatine supplementation affects muscle carnosine content in type 2 diabetic patients. Subjects were randomly assigned to receive either creatine (5 g·day–1) or placebo in a double-blind fashion. At baseline and after 12 weeks, carnosine content was evaluated in gastrocnemius and soleus muscles by using a 1H-MRS technique. No ch...