Vishal Gupta

• Master of Science
• Integral University

Saffron ( Crocus Sativus L.) is a highly prized spice crop renowned for its significant culinary and therapeutic applications, largely attributed to its bioactive constituents such as crocin, picrocrocin, and safranal. Despite its production is severely threatened by corm rot, particularly caused by the pathogenic fungus Fusarium oxysporum , which...

Microorganisms have emerged as a valuable source of metabolites with significant potential for various agricultural applications. Yeast metabolites encompass a broad spectrum of compounds, including organic acids, enzymes, vitamins, polysaccharides and bioactive secondary metabolites. Yeast-derived biofertilizers and biostimulants have demonstrated...

Microbial secondary metabolites which are low molecular weight bioactive compounds, are beneficial to agriculture in several ways. However, less attention has been paid to fungal secondary metabolites compared to those from bacteria. An assortment of secondary metabolites produced by the fungi during their growth and development are broadly categor...

Bacterial leaf blight (BLB) in rice, caused by the pathogen Xanthomonas oryzae pv. oryzae, is a significant agricultural problem managed through chemical control and cultivating rice varieties with inherent resistance to the bacterial pathogen. Research has highlighted the potential of using antagonistic microbes which can suppress the BLB pathogen...

Global climate change scenarios due to anthropogenic responses jeopardize ecosystem sustainability and hinder progress toward achieving the United nations (UN-SDGs). Achieving “natural carbon solutions” from terrestrial ecosystems is challenging due to decreasing arable land and increasing marginal land. Marine ecosystems representing a wider “natu...

Corm rot of saffron is the deadliest disease of saffron and a major bottleneck in its successful cultivation in Jammu and Kashmir, India. To date, only limited information has been made available for the monitoring, surveillance, and detection of plant pathogens associated with corm rot of saffron in this region. Incidence and severity of corm rot...

Citation: Amin, T.; Gupta, V.; Sharma, A.; Rai, P.K.; Razdan, V.K.; Sharma, S.K.; Singh, S.K.; Lone, J.A.; Yaqoob, M.; Singh, B.; et al. Distribution of Xanthomonas oryzae pv. Abstract: Rice is an important staple food for more than half of the world's population. Though the genetic potential of commonly cultivated varieties of rice is diminished d...

Pseudomonas fluorescens is ubiquitous in nature and having diverse mechanism of action which ameliorates the biotic and abiotic stresses and possess plant growth promotion activities in agricultural crops. Out of fifty isolates of fluorescent pseudomonads collected from saffron and paddy crops, thirty-five isolates were identified as P. fluorescens...

Saffron, comprising of dried stigmas of the plant known as Crocus sativus, is one of the most important and scantly cultivated agricultural products. It has been used as a precious spice for the last at least 3500 years. Due to its numerous medicinal qualities and pharmacological applications, it is considered as a “golden condiment”, and its deman...

Saffron (Crocus sativus L.) is considered as one of the most expensive spices. Fusarium corm rot of saffron, caused by Fusarium oxysporum, is known to cause severe yield losses worldwide. In the present study, efficacy of biocontrol agents (Trichoderma asperellum, Pseudomonas fluorescens, Pseudomonas aeruginosa, Pseudomonas putida, Bacillus stratos...

Aim: study the effect of Sacubitril/valsartan (SV) combination therapy on cardio-renal (CR) biomarkers in T2DM with preserved ejection fraction (pEF); diastolic dysfunction and or LVH on 2D echocardiogram (E) and elevated N-terminal prohormone B-type natriuretic peptide (NT-proBNP) >125. Methodology: between July and Sept 2018, 109 T2DM patients ag...

Aim: To compare the efficiency of canagliflozin (C1) 100mg vs. canagliflozin (C3) 300mg on highly sensitive C reactive protein (hs-CRP) and other cardio-renal (CR) biomarkers. Methodology: Between July and Sept 2018, a cohort of 190 T2DM patients aged 18-75 yrs, irrespective of baseline A1c, receiving SGLTi C1 or C3 were identified. A propensity sc...

Early blight of tomato caused by Alternaria solani is an economically important disease in all the tomato growing areas worldwide. The effect of weather variables on the per cent disease intensity(PDI) index of early blight were analyzed during the early summer season of five consecutive years from 2013 to 2017. The disease invariably appeared in t...

The use of synthetic mesh (e.g., polypropylene [PP] mesh) and biologic (e.g., porcine acellular dermal matrix (PADM)) for the repair of abdominal wall musculofascial has limitations associated with an increased risk of complications and finite properties, respectively. Silk fibroin (SF)-based scaffolds are fabricated with decorin blends (SFD) to cr...

Background: Preterm infants with respiratory distress syndrome (RDS) requiring surfactant therapy have been traditionally receiving surfactant by intubation surfactant and extubation technique (InSurE), which comprises of tracheal intubation, surfactant administration, and extubation. However, more recently noninvasive methods like least invasive...

We present a term neonate with severe sepsis, presenting on day 10 of life. The neonate presented with bilateral purulent eye discharge and hepatosplenomegaly. On investigation, persistent leucocytosis was observed and thus the possibility of leucocyte adhesion defect was considered. Flow cytometry confirmed the diagnosis.

259 T2DM patients with microalbuminuria eUACR >30 irrespective of their A1c, on standard glucose lowering, lipid lowering and ARB (telmisartan TM or valsartan Vs as first line BP lowering therapy until optimal dose was achieved, were followed-up for 2 years. Renal (Cr, eGFR, UACR) and CV (BP, BMI, Lipid profile, hs-CRP) parameters were assessed eve...

Methodology: 280 T2DM patients aged 18-75 years irrespective of their A1c, on standard glucose lowering, lipid lowering and BP lowering therapy were divided into 2 groups, group 1N (105 patients normoalbuminuria UACR <30) and group 2M (175 patients microalbuminuria eUACR >30). Both groups were followed-up for 2 years and assessed every 3-6 months f...

84 T2DM with microalbuminuria (eUACR) >30 aged 18-75 years irrespective of their A1c, on standard glucose, lipid and BP lowering therapy using telmisartan (Tm) or valsartan (Vs) were followed-up for 2 years. 2 groups were identified, Tm group and Vs group. Renal (Cr, eGFR, UACR) and CV (BP, BMI, Lipid profile, hs-CRP) markers were evaluated at 3-6...

Methodology: 175 T2DM patients on regular follow-up with microalbuminuria (eUACR >30), aged <75 years, irrespective of their A1c, on standard glucose, lipid and blood pressure lowering therapy using ARB (valsartan or telmisartan) were followed-up for 2 years. 2 groups were identified, Control group (Cn) on conventional dose CDARB’s and case (Cs) gr...

Supplementary file for Mote et al. 2019: S1 - A photograph of Cliona thomasi sp. nov.; S2.1-2.5 - Tables with raw data for C. thomasi tylostyle dimensions of the type material and additional material; S3.1-3.4 - Size frequency distributions of C. thomasi tylostyle lengths; S4.1-4.22 Raw data for C. thomasi spicule dimensions and descriptive statist...

Coral reef ecosystems depend on the balanced interplay of constructive and destructive processes and are increasingly threatened by environmental change. In this context bioeroding sponges play a significant role in carbonate cycling and sediment production. They occasionally aggravate erosional processes on disturbed reefs. Like other coral ecosys...

Aim: The present study was conducted to investigate the biocontrol potential of fluorescent pseudomonads in-vitro and in-vivo responsible for causing sheath blight of rice. Methodology: Indigenous isolates (20 nos.) of fluorescent pseudomonads, collected from the rhizosphere of basmati paddy fields from different locations of Jammu province, which...

Objective: The main aim of this study was to assess the clinical status and risk factors of Ischemic Heart Disease among patients. Material and Methods: This prospective observational study was conducted over a duration of six months at the Department of Medicine at Guru Gobind Singh Medical College, Hospital and Research Centre, Faridkot, Punjab,...

We present an 11-month-old girl child with complaints of constipation, cough, fever, vomiting and growth retardation. On examination, she had facial dysmorphism, hypertension and murmur. The genetic evaluation showed 7q microdeletion specific to Williams syndrome. Abdominal imaging was suggestive of nephrocalcinosis which is rare for this age group...

Heterogeneous memory management combined with server virtualization in datacenters is expected to increase the software and OS management complexity. State-of-the-art solutions rely exclusively on the hypervisor (VMM) for expensive page hotness tracking and migrations, limiting the benefits from heterogeneity. To address this, we design HeteroOS, a...

Background: The recommended treatment for patients with locally advanced cervical cancer is primary chemoradiation, which consists of platinum-based chemotherapy, external-beam radiation therapy (EBRT) to the pelvis, and cervical brachytherapy. Case: The patient was a 50-year-old woman had a large, fungating cervical mass. Pathology testing showed...

Methodology: Two hundred T2DM patients who were on standard glucose lowering agents and who may be on lipid and blood pressure lowering agents were optimised for conventional CV risk markers and followed for a period of 2 years. We evaluated CV risk using markers like BMI, HbA1c, Systolic blood pressure (SBP), diastolic BP (DBP), total cholesterol...

Objective: To evaluate effect of Canagliflozin (CA) on dose of other commonly co-administered antidiabetic, antihypertensive (AH) and lipid lowering drugs (AL) over a period of 12 months. Methodology: Fifty diabetes patients receiving glucose lowering therapy, AH and LL were treated with CA for a period of 12months. These patients were followed up...

Methodology: Two hundred T2DM patients on standard glucose lowering agents and who may be on lipid and blood pressure lowering agents were followed up for 2 years for improvement in CV risk markers like BMI, HbA1c, systolic blood pressure(S-BP), diastolic BP(D-BP), total cholesterol(TC), HDL, non-HDL, LDL, triglycerides(TG), cholesterol remnant(CR)...

Thirty-seven wheat germplasm were screened under artificial epiphytotic conditions against stripe rust of wheat at University Research Farm, Chatha, during Rabi, 2013–2014 and 2014–2015. On the basis of final rust severity (FRS), AURPC (Area Under Rust Progress Curve) and CI (Coefficient of Infection), 8 genotypes ((DWR 16, HD2281, VL616, K65, UP21...

Thirty one wheat germplasm lines were screened under natural epiphytotic conditions against stripe rust at University Research Farm, Chatha, during Rabi, 2014-15. On the basis of final rust severity (FRS), area under rust progress curve (AURPC) and coefficient of infection (CI), eight lines (Raj 4037, Sonara 64, NP 823, HPW 42, K9351, NIAW 301, PBW...

Studies were carried out from 2013 to 2015 with the objectives to isolate and identify some indigenous rhizobacterial strains against major soil-borne pathogens of brinjal. Seventy thizobacterial isolates were characterized based on colony characters, morphological and biochemical test and identified as Pseudomonas flourescens (30), P. aeruginosa (...

Introduction: Hypertension is a common disease which is also known as elevated blood pressure above the normal, i.e., systolic blood pressure above 130 mm Hg and diastolic blood pressure above 90 mm Hg. Hypertension is one of the highest prevailing diseases worldwide. Patients with hypertension are at higher risk of developing stroke, myocardial in...

During last decades, stripe rust has emerged as a major disease of wheat causing considerable yield loss in northern western plain and northern hill zones of India. Considering significant impact of the disease on wheat crop, field experiments were conducted during rabi seasons of 2013 and 2015 to evaluate the effect of different abiotic factors in...

Heterogeneous memory management combined with server virtualization in datacenters is expected to increase the software and OS management complexity. State-of-the-art solutions rely exclusively on the hypervisor (VMM) for expensive page hotness tracking and migrations, limiting the benefits from heterogeneity. To address this, we design HeteroOS, a...

Fifty wheat varieties were screened under artificial epiphytotic conditions against stripe rust of wheat during Rabi, 2013-14. On the basis of final rust severity (FRS), AURPC (Area Under Rust Progress Curve), r (Infection Rate) and CI (Coefficient of Infection), 10 lines exhibited partial resistance against the disease. PCR profiles of fifty wheat...

Twenty-five isolates of Pseudomonas fluorescens were isolated from healthy plants of tomato on Kings'B medium, for exploring their bio-efficacy potential against Fusarium oxysporum f.sp. lycopersici and Rhizoctonia solani, responsible for wilt complex disease. Out of all, six isolates (I-7, I-15, I-18, I-23, I-24 and I-25) significantly inhibited t...

Two major fungal pathogens, Fusarium oxysporum f. sp. lycopersici and Rhizoctonia solani were isolated from infected root, collar and stem regions of tomato plants. A total of 25 rhizobacterial isolates showing Gram-ve reaction were isolated from the rhizosphere of tomato fields. Six selected isolates, based on their biocontrol activity against the...

Our goal was to determine the clinical treatment response following radiation administered with or without chemotherapy for locally advanced cervical cancers in Honduras. This is a retrospective study of patients treated with either concurrent chemoradiation (CCRT) or external beam radiation therapy (EBRT) alone at a hospital in Tegucigalpa, Hondur...

Objectives: High-risk histology including UPSC, CC, and high-grade (G3) endometrioid adenocarcinoma (EAC) have a worse prognosis compared to G1-2 EAC. It is unknown whether G3EAC outcomes are more similar to UPSC/CC or to G1-2 EAC. The purpose of this study was to compare overall survival (OS) among UPSC, CC, and G1-3 EAC, for International Federa...

Purpose: Adjuvant radiation therapy (RT) was shown to improve local control in patients with high-intermediate risk (HIR) stage I endometrial cancer (EC) in randomized trials. Overall survival (OS) was not significantly different with adjuvant RT in these trials or subsequent meta-analyses; however, they were underpowered to assess OS. We used the...

This paper presents HeteroVisor, a heterogeneity-aware hypervisor, that exploits resource heterogeneity to enhance the elasticity of cloud systems. Introducing the notion of 'elasticity' (E) states, HeteroVisor permits applications to manage their changes in resource requirements as state transitions that implicitly move their execution among heter...

Objectives: Our aim was to assess current surgical practices and use of adjuvant therapy in the treatment of FIGO (International Federation of Gynecology and Obstetrics) stage I endometrioid endometrial cancer. Methods: A 19-question survey was developed and sent to all Society of Gynecologic Oncologist members by e-mail. Data were collected ano...

This paper presents HeteroVisor, a heterogeneity-aware hypervisor, that exploits resource heterogeneity to enhance the elasticity of cloud systems. Introducing the notion of 'elasticity' (E) states, HeteroVisor permits applications to manage their changes in resource requirements as state transitions that implicitly move their execution among heter...

The present paper aims to adapt a propagation model for the area between Haridwar and Rishikesh, Uttararkhand, India. The study is in continuation to the works by several authors which was carried out for the urban, suburban and rural regions on the basis of the data collected from the local operator. In this paper we compare the field measured dat...

Aims: The aim of this analysis was to assess the cost-effectiveness of switching from biphasic human insulin 30 (BHI), insulin glargine (IGlar), or neutral protamine Hagedorn (NPH) insulin (all ± oral glucose-lowering drugs [OGLDs]) to biphasic insulin aspart 30 (BIAsp 30) in people with type 2 diabetes in India, Indonesia, and Saudi Arabia. Meth...

Aim This study aimed to assess the cost-effectiveness of starting insulin therapy with biphasic insulin aspart 30 (BIAsp 30) in people with type 2 diabetes inadequately controlled on oral glucose-lowering drugs in Saudi Arabia, India, Indonesia, and Algeria. Methods The IMS CORE Diabetes Model was used to evaluate economic outcomes associated with...

Objectives We investigated associations between radiographic evidence of nodal extracapsular extension (rECE) and outcomes for locally advanced head and neck squamous cell cancers (LAHNC). Materials and methods We conducted a single-institution retrospective study of 258 consecutive LAHNC patients with accessible pretreatment contrast-enhanced nec...

Ad-Hoc network is an infrastructure – less network which is created by deploying the mobile nodes carrying wireless devices, capable of transferring data between each other and network topology is dynamic and random in such a type of networks. As we know that routing protocols basically defines the set of rules to be adopted in finding the path bet...

Mobile devices and applications exhibit highly diverse behavior in their usage and power/performance requirements. In order to accommodate such diversity, this paper presents ‘HeteroMates’ system that uses heterogeneous processors to extend the dynamic power/performance range of client devices, i.e., offer both high performance and reduced power co...

this paper we have explored a new dimension in image steganography and propose a deft method for image - secret data - keyword (steg key) based sampling, encryption and embedding the former with a variable bit retrieval function. The keen association of the image, secret data and steg key, varied with a pixel dependent embedding results in a highly...

This paper presents a software-controlled technique for managing the heterogeneous memory resources of next generation multicore platforms with fast 3D die-stacked memory and additional slow off-chip memory. Implemented for virtualized server systems, the technique detects the 'hot' pages critical to program performance in order to then maintain th...

Dynamic voltage scaling is a technique for lowering energy consumption in microelectronic systems when the performance required is at times lower than the system's peak capability. This paper proposes a new voltage scaling technique for asynchronous systems which allows fine-grain scaling of supply voltage, i.e. each stage in the pipeline is allowe...

Brinjal crop suffers many biotic stresses including soil borne diseases. Studies were carried out from 2007 to 2009 with the objective to know the status of these diseases, causal agents involved and frequency of the pathogens associated. The soil borne diseases were found to prevail in all the areas surveyed. The pooled data of the years 2008 and...

Indian organizations are witnessing a change in systems, management cultures and philosophy due to the global alignment of Indian organizations. There is a need for multi skill development. Over the years, highly skilled and knowledge based jobs are increasing while low skilled jobs are decreasing. This calls for future skill mapping through proper...

ABSTRACT The business process outsourcing in India is expanding at a rapid speed in spite of global financial crisis of 2008. It is absorbing large number of talent pool of employees but has always been characterized by ungodly hours, monotonous job, low perceived value, dispirited efficiency resulting to high attrition level. Notwithstanding the e...

Heterogeneous processors, consisting of a mix of high-performance 'brawny' processors and low-power 'wimpy' processors, have been proposed to achieve higher energy-efficiency by making it possible for different applications within a diverse mix of workloads to be run on the most appropriate cores. This paper performs a comparative analysis of such...

Exponentially increasing transistor density with each processor generation, along with constant chip-level power budgets and a slower rate of improvement in transistor power dissipation, exponentially decreases the percentage of transistors that can switch on simultaneously. Such 'over-provisioned multicore' systems require active power management...

Software cost estimation is the process of predicting the effort required to develop a software system. Accurate cost estimation helps us complete the project within time and budget. For completing the project in time and budget, one must have efficient estimation technique for predicting project efforts. Artificial neural network is a promising te...

Abstract: In the present economic circumstances the country is witnessing rapid expansion of industrial activity. With enrichment and enhancement of information & Communication Technology the complexity of human factor have also increased substantially. Insurance industry in the country is passing through the acid test. Human resource mobalisation...

Major rice growing areas of Jammu sub-tropics (Jammu, Samba and Kathua Districts) were surveyed to ascertain the status and distributions of brown spot of rice during 2011 to 2012. The disease was reported from all the areas with area under brown spot progress curve (AUBSPC) ranging between 3150 and 3560, 3025.00 and 3100, and 2921 and 31050 in Jam...

Software cost estimation is the process of predicting the effort required to develop a software system. Accurate cost estimation helps us complete the project within time and budget. There are lots of methods are there for efforts and cost estimation, but people do not know how to use these methods. This paper provides a general overview of softwar...

In the recent times the study of signal propagation models are under continuous reviewand currently a lot of work is being done on prediction of path losses associated with different kinds of environments, but the exactness of each model deployed is valid only for a small frame of fixed parameters which are the fundamentals of it. An exact radio pr...

In any kind of network planning it is the central task to estimate and thus analyze propagation characteristics of a radio system through a medium in order to state accuracy in signal parameters for efficient network planning. The system must necessarily incorporate in itself the ability to predict the accurateness of radio propagation behavior. Th...

Heterogeneous multicore processors (HMPs), consisting of cores with different performance/power characteristics, have been proposed to deliver higher energy efficiency than symmetric multicores. This paper investigates the opportunities and limitations in using HMPs to gain energy-efficiency. Unlike previous work focused on server systems, we focus...

This paper presents HeteroMates, a solution that uses heterogeneous processors to extend the dynamic power/performance range of client devices. By using a mix of different processors, HeteroMates offers both high performance and reduced power consumption. The solution uses core groups as the abstraction that groups a small number of heterogeneous c...

Multicore processors have been effective in scaling appli-cation performance by dividing computation among multi-ple threads running in parallel. However, application per-formance does not necessarily improve as more cores are added. Application performance can be limited due to mul-tiple bottlenecks including contention for shared resources such a...

Users of modern time characterize mobile communication service providence not only from the point of view of service provider's perspective but also from user's perspective. This has led to the improvement in standards of services offered & has also led to more advanced wireless technology for optimal performance even in the mobile environments. Th...

Power and design constraints have forced the semiconductor industry to look at alternate solutions like heterogeneous chip multiprocessors to continue application performance scaling and improve energy efficiency of multicore processors. In this paper, we present an opportunity analysis of heterogeneous chip multiprocessors in the context of datace...

A multifaceted strategy using a composite of anti-cancer nanotherapeutic and natural biomaterials silk fibroin (SF) and chitosan (CS) blend scaffolds was investigated for the treatment of a tissue defect post-tumor resection by providing local release of the therapeutic and filling of the defect site with the regenerative bioscaffolds. The scaffold...

The purpose of this study was to investigate the potential of silk fibroin and chitosan blend (SFCS) biological scaffolds for the purpose of cartilage tissue engineering with applications in tracheal tissue reconstruction. The capability of these scaffolds as cell carrier systems for chondrocytes was determined in vitro and cartilage generation in...

The semiconductor industry is continuing to harness performance gains through Moore's Law by developing multicore chips. While thus far these architectures have incorporated symmetric computational components, asymmetric multicore processors (AMPs) have been proposed as a possible alternative to improve power efficiency. To quantify the tradeoffs a...

Regenerative tissue engineering requires biomaterials that would mimic structure and composition of the extracellular matrix to facilitate cell infiltration, differentiation, and vascularization. Engineered scaffolds composed of natural biomaterials silk fibroin (SF) and chitosan (CS) blend were fabricated to achieve fibrillar nano-structures align...

The treatment of disease in the future will be influenced by the ability to produce therapeutic formulations that have high availability at the disease site, sustained and long-term release, with minimal to no toxicity to healthy tissues. Biologically derived delivery systems offer promise in this regard owing to minimization of adverse effects whi...

Modern mobile applications demand high performance from low supply voltages to reduce power (extend battery life) and survive low breakdown voltages (imposed by sub-micron CMOS technologies), which is why precise low-impedance sub-bandgap references (below 1.2V) that are independent of process, package stress, supply, load, and temperature are crit...

Biologically derived nanoparticles (<100 nm) were fabricated for local and sustained therapeutic curcumin delivery to cancer cells. Silk fibroin (SF) and chitosan (CS) polymers were blended noncovalently to encapsulate curcumin in various proportions of SF and CS (75:25, 50:50, and 25:75 SF:CS) or pure SF at two concentrations (0.1% w/v and 10% w/v...