Virginie Molinier

Korian France Santé

Objective: Pulmonary rehabilitation (PR) is the gold standard treatment for improving the health status of individuals with chronic respiratory diseases (CRD). However, to achieve lasting results, the adoption and maintenance of a physically active lifestyle are necessary. Unfortunately, the trajectories of change in physical activity (PA) and sede...

Objectives: While dyspnea is the main symptom in chronic obstructive pulmonary disease (COPD), it is often inadequately evaluated in pulmonary rehabilitation (PR), as it is typically measured using only the impact dimension (ID). However, dyspnea is a multidimensional construct including perception (PD) and emotional (ED) domains. Our work aimed to...

Due to the high prevalence and persistence of long COVID, it is important to evaluate the safety and efficacy of pulmonary rehabilitation (PR) for patients who experience long-lasting symptoms more than six months after initial COVID-19 onset. Enrolled patients were admitted for a four-week in-patient-PR due to long COVID symptoms (n = 47). The saf...

Pulmonary rehabilitation (PR) in patients with COPD improves quality of life, dyspnea, and exercise tolerance. However, 30 to 50% of patients are “non-responders” (NRs) according to considered variables. Surprisingly, peripheral muscle force is never taken into account to attest the efficacy of PR, despite its major importance. Thus, we aimed to es...

This study aimed to assess the time-course of changes in multidimensional fatigue and functional exercise capacity and their associations during an inpatient pulmonary rehabilitation (PR) program. Seventy COPD patients from three centres were enrolled for a four-week PR program and were evaluated before (T0) and at the end of each week (T1, T2, T3,...

Global warming is pushing populations outside their range of physiological tolerance. According to the environmental envelope framework, the most vulnerable populations occur near the climatic edge of their species' distributions. In contrast, populations from the climatic center of the species range should be relatively buffered against climate wa...

Background Pulmonary rehabilitation (PR) is the cornerstone of nonpharmacological treatments in chronic respiratory disease (CRD) management. PR can be performed in different settings, the most frequent of which are inpatient (inPR) and outpatient (outPR) management. In the literature, these two distinct modalities are generally considered to be th...

Burgundy truffles are heterothallic ascomycetes that grow in symbiosis with trees. Despite their esteemed belowground fruitbodies, the species’ complex lifecycle is still not fully understood. Here, we present the genetic patterns in three natural Burgundy truffle populations based on genotyped fruitbodies, ascospore extracts, and ectomycorrhizal r...

Introduction Hypoxaemia is a frequent complication of chronic obstructive pulmonary disease (COPD). To prevent its consequences, supplemental oxygen therapy is recommended by international respiratory societies. However, despite clear recommendations, some patients receive long-term oxygen therapy (LTOT), while they do not meet prescription criteri...

Background The effectiveness of pulmonary rehabilitation (PR) is a critical issue for chronic obstructive pulmonary disease (COPD) patients. However, PR response is marked by a strong heterogeneity, partially unexplained to date. We hypothesized that personality traits defined by the Five-Factor Model could modulate the effect of inpatient-PR. Obj...

Despite its status as a highly-prized and coveted fungi in gastronomy, many aspects of the subterranean life cycle of the Burgundy truffle (Tuber aestivum) are still unknown, because in situ observations of the formation and maturation of truffle fruitbodies remain difficult. Here, we adopted a suite of archaeological fine-scale excavating techniqu...

Considérant le fait que les activités physiques et sportives (APS) peuvent à la fois améliorer et aggraver la situation en matière de changements climatiques, notre équipe a récemment publié une revue systématique faisant la synthèse des liens entre changement climatique et l’APS. Cette revue systématique compile plus de 60 articles. L’objectif de...

Background Climate change impacts are associated with dramatic consequences for human health and threaten physical activity (PA) behaviors.Objective The aims of this systematic review were to present the potential bidirectional associations between climate change impacts and PA behaviors in humans and to propose a synthesis of the literature throug...

https://www.clinicaltrials.gov/ct2/show/NCT04010825?term=dyspnemo&draw=2&rank=1

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=209823

POST PRINT : https://avuer.hypotheses.org/files/2021/05/Bernard-2021-Climate-change-physical-activity-and-sport-a-systematic-review.pdf The climate change manifestations are associated with dramatic consequences for human health and threat physical activity behaviors.Objective The aims of this systematic review were to present the potential bidirec...

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=166546

Truffle fungi are well known for their enticing aromas partially emitted by microbes colonizing truffle fruiting bodies. The identity and diversity of these microbes remain poorly investigated, because few studies have determined truffle-associated bacterial communities while considering only a small number of fruiting bodies. Hence, the factors dr...

Le tableau ci-dessous propose une traduction française de la taxonomie des techniques de changement de comportement élaborée par Michie et al. (2013). Cette taxonomie renvoie aux techniques de changement de comportement (acronyme anglais 'BCT' signifiant Behaviour Change Techniques) qui correspondent aux composantes concrètes d'une intervention vis...

Tuberaceae is one of the most diverse lineages of symbiotic truffle-forming fungi. To understand the molecular underpinning of the ectomycorrhizal truffle lifestyle, we compared the genomes of Piedmont white truffle (Tuber magnatum), Périgord black truffle (Tuber melanosporum), Burgundy truffle (Tuber aestivum), pig truffle (Choiromyces venosus) an...

Although Tuber aestivum is widely distributed across Europe, little is known about its biology and ecology. We assess the vegetation composition of wild T. aestivum sites and use this information to characterise suitable habitats in Fagus sylvatica, Carpinus betulus and Ostrya carpinifolia (FCO) forests. Plant species composition at 16 naturally co...

Despite an increasing demand for Burgundy truffles (Tuber aestivum), gaps remain in our understanding of the fungus’ overall lifecycle and ecology. Here, we compile evidence from three independent surveys in Hungary and Switzerland. First, we measured the weight and maturity of 2,656 T. aestivum fruit bodies from a three-day harvest in August 2014...

This excel-file contains all data relevant to our manuscript. (XLSX)

Prod 2017-339 équipe SPE IPM UB

Although the Burgundy truffle (Tuber aestivum) is an ectomycorrhizal fungus of important economic value, its subterranean life cycle and population biology are still poorly understood. Here, we determine mating type and simple sequence repeat (SSR) maternal genotypes of mapped fruiting bodies to assess their genetic structure within two naturally c...

Mushrooms have a special position in many cultures where they are used as food, medicine, handicrafts, have special cultural significance as symbols or in rituals and are a motivation for forest recreation. However, there is also a dark side to mushrooms which are also associated with poisoning, decay and death. This dichotomy is reflected in the s...

The most frequently encountered symbiont on tree roots is the ascomycete Cenococcum geophilum, the only mycorrhizal species within the largest fungal class Dothideomycetes, a class known for devastating plant pathogens. Here we show that the symbiotic genomic idiosyncrasies of ectomycorrhizal basidiomycetes are also present in C. geophilum with sym...

Tuber aestivum (Vittadini, Monographia tuberacearum, 1831) is an ectomycorrhizal fungus that establishes a symbiosis with various host tree species, such as oak, beech, and hazel. The mycorrhizas of T. aestivum show a characteristic tangled hairy feature, due to the presence of many curled, interwoven cystidia. Morphological features of the ascocar...

Climate projections predict higher precipitation variability with more frequent dry extremes1. CO2 assimilation of forests decreases during drought, either by stomatal closure2 or by direct environmental control of sink tissue activities3. Ultimately, drought effects on forests depend on the ability of forests to recover, but the mechanisms control...

Tuber species are ectomycorrhizal ascomycetes establishing relationships with different host trees and forming hypogeous fruiting bodies known as truffles. Among Tuber species, Tuber aestivum Vittad. has a wide distributional range being found naturally all over Europe. Here, we performed large-scale population genetic analyses in T. aestivum to (i...

Truffles are symbiotic fungi in high demand by food connoisseurs. Improving yield and product quality requires a better understanding of truffle genetics and aroma biosynthesis. One aim here was to investigate the diversity and fine-scale spatial genetic structure of the Burgundy truffle Tuber aestivum. The second aim was to assess how genetic stru...

Truffles, i.e. tree root-associated fungal fruiting bodies, clearly range among the world’s most exclusive delicacies. Despite the quite restricted natural geographic occurrence of one of the most renowned fungal species, namely Tuber melanosporum, the development of inoculation procedures in the late 1960s made it possible to enlarge its productio...

For almost 2 centuries it has been disputed whether Tuber aestivum and Tuber uncinatum constitute two different species of truffles. Molecular markers have been applied previously to contribute to resolving this question, coming to different conclusions. In this study, we address this question by analyzing the genetic structure of truffles assigned...

Truffles are ectomycorrhizal Ascomycota fungi belonging to the Tuberaceae family and more specifically to the Tuber genus. More than thirty Tuber species are currently described in Europe. In this thesis, we specifically focused on the Tuber aestivum-uncinatum model. This truffle is commonly called "Burgundy Truffle" and has a gastronomic and cultu...

SPE IPM CT2 Discipline : Sciences de la Vie

Premise of the study: Tuber aestivum, the most common truffle in Europe, tends to take an important place in the truffle economic market. For the first time, microsatellites primers were developed to investigate the polymorphism within this species. Methods and results: Using direct shotgun pyrosequencing, fifteen polymorphic microsatellites were...

Peer-reviewed letter Truffles (Tuber spp) – the aromatic fruiting bodies of fungi that grow underground and symbiotically colo-nize the roots of hazels, oaks, and other trees or shrubs – are a luxury food item, with prices often compa-rable to those of caviar. The exorbi-tant prices of truffles reflect a decreasing worldwide production (Hall et al....