Virgilio Mattoli

Virgilio Mattoli
Istituto Italiano di Tecnologia | IIT · Center for Micro-BioRobotics

About

294
Publications
88,282
Reads
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8,026
Citations
Citations since 2017
91 Research Items
5994 Citations
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201720182019202020212022202302004006008001,0001,200
201720182019202020212022202302004006008001,0001,200
201720182019202020212022202302004006008001,0001,200
Additional affiliations
November 2009 - August 2020
Italian Institute of Technology (IIT)
Position
  • Group Leader
November 2008 - December 2008
Waseda University
Position
  • Researcher
November 2005 - December 2005
Waseda University
Position
  • PhD Student
Education
September 1993 - May 2000
Scuola Normale Superiore di Pisa
Field of study
  • Chemistry

Publications

Publications (294)
Article
Full-text available
Bio-responsive nanocomposites with facile fabrication and rational design are of great importance in the diagnosis and treatment of cancer. Herein, the combination of bioimaging due to the presence of QD and controlled drug delivery via nanogel was employed for cancer treatment. To this aim, we fabricated a traceable and bioresponsive fluorescent ac...
Article
Full-text available
Bioinspired functional surfaces are attracting increasing interest in surface engineering, mostly in the field of wettability. The Salvinia‐effect is a remarkable example of superficial air retention and drag force reduction caused by selective chemical coating (super‐hydrophobic wax and hydrophilic dead cells) and peculiar 3D hierarchical morpholo...
Article
Full-text available
The COVID-19 pandemic has further confirmed to the community that direct contact with contaminated surfaces and objects represents an important source of pathogen spreading among humans. Therefore, it is of paramount importance to design effective germicidal paints to ensure a rapid and potent disinfectant action of surfaces. In this work, we desig...
Article
The oral pathway is the preferred drug administration route in pharmaceutical sciences, however, the most employed ‘highly active’ drug candidates suffer from poor water solubility. The aim of this study was to develop repaglinide (RL)-loaded chitosan-grafted mesoporous silica material (MSM) to enhance drug dissolution. Such enhanced dissolution wa...
Article
The design and development of multifunctional injectable hydrogels with high photothermal antibacterial activity and shape adaptability to accelerate bacteria-infected wound healing is of critical importance in clinical applications. In this study, a hybrid hydrogel composed of gelatin, iron, and MnO2 nanosheets was prepared by multiple interaction...
Article
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MXenes (viz., transition metal carbides, carbonitrides, and nitrides) have emerged as a new subclass of 2D materials. Due to their outstanding physicochemical and biological properties, MXenes have gained much attention in the biomedical field in recent years, including drug delivery systems, regenerative medicine, and biosensing. Additionally, the...
Article
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In this study, we present a thermoplasmonic transparent ink based on a colloidal dispersion of indium tin oxide (ITO) nanoparticles, which can offer several advantages as anti-counterfeiting technology. The custom ink could be directly printed on several substrates, and it is transparent under visible light but is able to generate heat by absorptio...
Article
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Anthropogenic toxic vapour and gases are a worldwide threat for human health and to the environment. Therefore, it is crucial to develop highly sensitive devices that guarantee their rapid detection. Here, we prepared redox-switchable colloids by the in-situ reduction of 2,3,5-triphenyl-2H-tetrazolium (TTC) into triphenyl formazan (TF) stabilised w...
Preprint
Full-text available
Poly(vinylidene fluoride-trifluoroethylene, P(VDF-TrFE)) and P(VDF-TrFE)/barium titanate nanoparticle (BTNP) films are prepared and tested as substrates for neuronal stimulation through direct piezoelectric effect. Films are characterized in terms of surface, mechanical, and piezoelectric features before in vitro testing on SH-SY5Y cells. In partic...
Article
Direct laser writing (DLW) is an innovative technology based on two‐photon polymerization processes which allow the 3D printing of architectures with arbitrary complexity at the (sub)micrometer scale. While most of the research interest in this field relies on additive manufacturing, subtractive approaches can be extremely helpful in nano/microfabr...
Article
Full-text available
Cancer is one of the top life-threatening dangers to the human survival, accounting for over 10 million deaths per year. Bioactive glasses have developed dramatically since their discovery 50 years ago, with applications that include therapeutics as well as diagnostics. A new system within the bioactive glass family, mesoporous bioactive glasses (M...
Article
Rapid self-healing materials are highly demanded to contract plastic pollution and increase the materials service life. In this work, we designed a self-healing thermo-responsive nanocomposite containing homogeneously dispersed indium tin...
Article
Nature contains abundant systems that can significantly alter their structures and properties to adapt to the surrounding environment. Through natural selection and unceasing evolution, hierarchical architectures and sophisticated strategies have been created by nature to achieve optimally adapted materials for biomedical applications. The developm...
Article
Background: The ability to fabricate components capable of performing actuation in a reliable and controlled manner is one of the main research topics in the field of microelectromechanical systems (MEMS). However, the development of these technologies can be limited in many cases by 2D lithographic techniques employed in the fabrication process. D...
Article
Background: The ability to fabricate components capable of performing actuation in a reliable and controlled manner is one of the main research topics in the field of microelectromechanical systems (MEMS). However, the development of these technologies can be limited in many cases by 2D lithographic techniques employed in the fabrication process. D...
Article
Full-text available
Excessive and unwarranted administration of antibiotics has invigorated the evolution of multidrug-resistant microbes. There is, therefore, an urgent need for advanced active compounds. Ionic liquids with short-lived ion-pair structures are highly tunable and have diverse applications. Apart from their unique physicochemical features, the newly-dis...
Article
Full-text available
Antimicrobial Ionic Liquids The antimicrobial effect of ionic liquids (positive and negative charge) could be tuned by tailoring their structural features. In article number 2104148, Eric Lichtfouse, Franklin R. Tay, Pooyan Makvandi, and co-workers comprehensively discuss the antibacterial activity of ionic liquids in biomedical applications such a...
Article
Full-text available
Recent advancements in the field of electronics have paved the way to the development of new applications, such as tattoo electronics, where the employment of ultraconformable devices is required, typically achievable with a significant reduction in their total thickness. Organic materials can be considered enablers, owing to the possibility of dep...
Article
Full-text available
Unwanted icing has major safety and economic repercussions on human activities, affecting means of transportation, infrastructures, and consumer goods. Compared to the common deicing methods in use today, intrinsically icephobic surfaces can decrease ice accumulation and formation without any active intervention from humans or machines. However, su...
Article
Humans are exposed to nanoscopical nanobiovectors (e.g. coronavirus SARS-CoV-2) as well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or intentionally. Understanding the interactions of cell membranes with these abiotic and biotic nanostructures will facilitate scientists to design better functional nanomaterials for...
Article
Quantum cascade lasers (QCLs) represent a most promising compact source at terahertz (THz) frequencies, but efficiency of their continuous wave (CW) operation still needs to be improved to achieve large-scale exploitation. Here, we demonstrate highly efficient operation of a subwalength microcavity laser consisting of two evanescently coupled whisp...
Article
Polypyrrole is an example of inherently electrically conductive polymers that is employed in the biomedical arena because of its low cost, excellent electroconductive properties, and good biocompatibility. Because many body tissues respond to electrical fields, polypyrrole-based nanocomposites have become an important class of bio-conductive materi...
Data
Antimicrobial activities of ionic liquids have fascinated biochemists, microbiologists, and medical scientists. The antimicrobial effect of ionic liquids could be tuned by tailoring their structural features. This work comprehensively discusses the antibacterial mechanism and structure-properties relationship of ionic liquids on their bactericidal...
Data
The antibacterial properties of #ionic_liquids are attributed to: I) #Adsorption: ionic liquids are attracted to the cell membranes; II) #Electrostatic interaction: the deactivation of membrane proteins and interaction of the ionic liquid with membrane phospholipids; III) #Penetration: disorganization and disintegration of the phospholipid bila...
Article
Non-spherical metal nanomaterials such as noble metal or transition metal dichalcogenides and MXenes have been employed in different biomedical facets. Because the biological properties of these nanocompounds are governed by their architecture and composition, such factors should be considered prior to their adoption for clinical use. The architect...
Article
Full-text available
Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner. Stimuli-responsive MN patches represent emerging drug delivery systems that release cargos on-demand as a response to internal or external triggers. I...
Article
The cover shows a self‐adhering, ultraconformable, organic electrode assembly measuring surface potentials on a Venus flytrap as studied by Fabian Meder, Virgilio Mattoli, Barbara Mazzolai and co‐workers (article number 2001182). The electrodes are easy‐to‐apply, light‐weight, and long‐term‐performing. Utilizable to record and bidirectionally stimu...
Preprint
Full-text available
3D and 4D printing are cutting-edge technologies for precise and expedited manufacturing of objects ranging from plastic to metal. Recent advances in 3D and 4D printing technologies in dentistry and maxillofacial surgery enable dentists to custom design and print surgical drill guides, temporary and permanent crowns and bridges, orthodontic applian...
Article
Full-text available
Injectable materials have shown great potential in tissue engineering applications. However, bacterial infection is one of the main challenges in using these materials in the field of regenerative medicine. In this study, biogenically synthesized silver nanoparticle-decorated multi-walled carbon nanotubes (Ag/MWCNTs) were deployed for adorning biog...
Preprint
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Micro/nano electro-mechanical systems (MEMS/NEMS) are constantly attracting an increasing attention for their relevant technological applications in fields ranging from biology, medicine, ecology, energy to industry. Most of the performances of micro-nanostructured devices rely on both the design and the intrinsic properties of the constituent mate...
Article
In the sphere of liver tissue engineering (LTE), 3D bioprinting has emerged as an effective technology to mimic the complex in vivo hepatic microenvironment, enabling the development of functional 3D constructs with potential application in the healthcare and diagnostic sector. This review gears off with a note on the liver's microscopic 3D archite...
Article
Full-text available
The electrical signals in plant's physiological processes are of great interest in biology, biohybrid robotics, and sensors for interfacing the living organisms with an electronic readout and control. This paper reports on the application of conformable, self‐adhering surface electrodes for the measurement and bidirectional stimulation of electrica...
Article
Full-text available
Factors affecting microneedle insertion into skin are reviewed.The use of artificial and computational skin models for the simulation of needle insertion is summarized.Skin structures and models, as well as mechanical analyses, used to determine transdermal microneedle ability to insert into skin are highlighted in the review. Factors affecting mic...
Article
Full-text available
Organic printed electronics has proven its potential as an essential enabler for applications related to healthcare, entertainment, energy, and distributed intelligent objects. The possibility of exploiting solution‐based and direct‐writing production schemes further boosts the benefits offered by such technology, facilitating the implementation of...
Article
Full-text available
Conformable electronics is an emerging and innovative research field investigating functional materials and electronic devices capable of adhering and conforming to non-planar surfaces such as the human skin. Conformable devices find applications of high economical and scientific interest in healthcare, human-machine interfaces, wearable electronic...
Article
Full-text available
The development of dry, ultra-conformable and unperceivable temporary tattoo electrodes (TTEs), based on the ink-jet printing of poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) on top of commercially available temporary tattoo paper, has gained increasing attention as a new and promising technology for electrophysiological record...
Article
A novel tattooable, ultrathin, green organic light‐emitting diode (OLED) fabricated on top of commercial temporary tattoo paper, is demonstrated. The transfer mechanism relies on dissolution of the sacrificial layer typically incorporated in paper‐tattoos. The ready‐to‐use device can be stored on the tattoo substrate and released on the target surf...
Article
Full-text available
Among smart materials, self-healing is one of the most studied properties. A self-healing polymer can repair the cracks that occurred in the structure of the material. Polyketones, which are high-performance thermoplastic polymers, are a suitable material for a self-healing mechanism: a furanic pendant moiety can be introduced into the backbone and...
Article
For large-scale graphene applications, such as the production of polymer-graphene nanocomposites, exfoliated graphene oxide (GO) and its reduced form (rGO) are presently considered to be very suitable starting materials, showing enhanced chemical reactivity with respect to pristine graphene, in addition to suitable electronic properties (i.e., tuna...
Article
3D and 4D printing are cutting-edge technologies for precise and expedited manufacturing of objects ranging from plastic to metal. Recent advances in 3D and 4D printing technologies in dentistry and maxillofacial surgery enable dentists to custom design and print surgical drill guides, temporary and permanent crowns and bridges, orthodontic applian...
Preprint
Full-text available
Development of dry, ultra-conformable and unperceivable temporary tattoo electrodes (TTEs), based on the ink-jet printing of PEDOT:PSS on top of commercially available temporary tattoo paper, has gained increasing attention as a new and promising technology for electrophysiological recordings on skin. In this work we present a TTEs epidermal sensor...
Article
Full-text available
In this work, the use of fluorescent molecular rotors such as 9-(2,2-dicyanovinyl)julolidine (DCVJ) and 2,3-bis(4-(phenyl(4-(1,2,2-triphenylvinyl) phenyl)amino)phenyl)fumaronitrile (TPETPAFN)) was proposed for the real-time monitoring of polyurethane (PU) formation in a solution of dimethylacetamide starting with 4,4’-methylenediphenyl diisocyanate...
Article
Full-text available
The lack of efficient targeting strategies poses significant limitations on the effectiveness of chemotherapeutic treatments. This issue also affects drug-loaded nanocarriers, reducing nanoparticles cancer cell uptake. We report on the fabrication and in vitro characterization of doxorubicin-loaded magnetic liposomes for localized treatment of live...
Article
Full-text available
The perylene bisimide derivative Paliogen Black (P‐black) is proposed as a new chromogenic probe that shows visible (vis) and near‐infrared (NIR) responses after mechanical solicitations of host linear low‐density polyethylene (LLDPE) films. P‐black is reported to display strong absorption in the vis spectrum and unusual reflective and cooling feat...
Chapter
The new emerging area of conformable electronics regards a class of materials and electronic devices that are able to adhere and conform to the skin or to other tissues and complex-shaped surfaces. Aim of this chapter is to review the main challenges, strategies and recent advancements in the field of conformable organic electronics. Principles and...
Preprint
Full-text available
Organic printed electronics has proven its potential as an essential enabler for applications related to healthcare, entertainment, energy and distributed intelligent objects. The possibility of exploiting solution-based and direct-writing production schemes further boosts the benefits offered by such technology, facilitating the implementation of...
Article
Full-text available
In this work, we prepared color-changing colloids by using the electrostatic self-assembly approach. The supramolecular structures are composed of a pH-responsive polymeric surfactant and the water-soluble porphyrin 5,10,15,20-tetrakis-(sulfonatophenyl)porphyrin (TPPS). The pH-responsive surfactant polymer was achieved by the chemical modification...
Article
Full-text available
The increasing diffusion of portable and wearable technologies results in a growing interest in electronic devices having features such as flexibility, lightness‐in‐weight, transparency, and wireless operation. Organic electronics is proposed as a potential candidate to fulfill such needs, in particular targeting pervasive radio‐frequency (RF) appl...
Article
Full-text available
In this work, we investigated the functionalization of reduced graphene oxide (rGO) with 2-(dodecen-1-yl) succinic anhydride (TPSA) to increase the rGO effective interactions with organic solvents both in liquid and vapor phases. Thermogravimetric analysis, STEM, XPS, FTIR-ATR, and Raman spectroscopy confirmed the effective functionalization of rGO...
Article
Full-text available
In this work, we investigated the functionalization of polyketone 30 (PK30) with glycyl-glycine (Gly-Gly) via the Paal–Knorr reaction with the aim of homogenously dispersing two types of reduced graphene oxide (rGO, i.e., lrGO and hrGO, the former characterized by a lower degree of reduction in comparison to the latter) by non-covalent interactions...
Article
Photoresponsive components for electric and electronic systems have received considerable attention, mainly due to the low cost of used materials and their manufacturing in mild conditions. Optically responsive materials have been prepared blending polymers with photochromic molecules to obtain systems with tuneable properties. Among photoresponsiv...
Article
Direct laser writing methods based on two‐photon polymerization (2PP) are powerful tools for the on‐demand printing of precise and complex 3D architectures at the micro and nanometer scale. While much progress was made to increase the resolution and the feature size throughout the years, by carefully designing a material, one can confer specific fu...
Article
Cerium oxide nanoparticles (nanoceria, NC) have attracted much attention in biomedicine due to their surface composition that confers interesting redox activities and regenerative properties. Studies have demonstrated that the application of nanoparticles in biomedicine can influence components of hemostatic system, inducing blood clotting, alterat...
Article
Full-text available
Progress towards green and autonomous energy sources includes harnessing living systems and biological tissue. It is recently discovered that the cuticle‐cellular tissue bilayer in higher plant leaves functions as an integrated triboelectric generator conductor couple capable of converting mechanical stimuli into electricity. Here, it is investigat...
Article
Piezoelectric films of poly(vinylidenedifluoride-trifluoroethylene) (P(VDF-TrFE)) and of P(VDF-TrFE) / boron nitride nanotubes (BNNTs) were prepared by cast-annealing and used for SaOS-2 osteoblast-like cell culture. Films were characterized in terms of surface and bulk features, and composite films demonstrated enhanced piezoresponse compared to p...
Article
In article number 1700325, Francesco Greco, Mario Caironi and co‐workers present an innovative transfer technique for the deposition of contacts on top of semi‐conductive organic layers based on tattoo paper. Easy to perform and stress‐free, the tattoo release is proved to be a valid alternative to classic transfer procedures. The technique is demo...
Article
Conformable electronics refers to a class of electronic devices that have the ability to conformally adhere onto nonplanar surfaces and materials, resulting particularly appealing for skin‐contact applications, such as the case of skin‐worn unobtrusive (bio)sensors for healthcare monitoring. Conformability can be addressed by integrating basic elec...
Article
Full-text available
This paper provides the very first definition of “growing robots”: a category of robots that imitates biological growth by the incremental addition of material. Although this nomenclature is quite new, the concept of morphological evolution, which is behind growth, has been extensively addressed in engineering and robotics. In fact, the idea of rep...