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Virendra S. Rana

Virendra S. Rana
Indian Agricultural Research Institute, New Delhi, India · Natural Product Chemistry, Division of Agricultural Chemicals

Doctor of Philosophy
Natural Product Chemistry

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113
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Publications

Publications (113)
Article
The cultural practice was the only crop protection tool during the early days when agriculture came into existence followed by the use of natural pesticides, which included plant and mineral-based products. The earlier record showed that Sumerians used sulfur in 3000 BC while Greeks and Romans used ash, oil, and sulfur in 600BC as pest control agen...
Article
Full-text available
Climate change is shifting agricultural production, which could impact the economic and cultural contexts of the oilseed industry, including sesame. Environmental threats (biotic and abiotic stresses) affect sesame production and thus yield (especially oil content). However, few studies have investigated the genetic enhancement, quality improvement...
Article
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The present study reports, bioefficacy evaluation of effective compounds against Meloidogyne incognita and Sclerotium rolfsii in pot cultured tomato. The identified five most effective compounds , i.e. (2E)-1-(4-Methylphenyl)-3-ferrocenyl-prop-2-en-1-one (6g), (2E)-1-(4-Methoxyphenyl)-3-ferrocenyl-prop-2-en-1-one (6h), (2E)-1-(3-Bromophenyl)-3-ferr...
Article
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Botanical insecticides are known to affect insects through various mode of action which includes toxicity through ingestion, contact, antifeedant, growth inhibition, repellency, etc. The present study was aimed to explore the potential of Murraya paniculata leaf extracts against two important insect pests’, a storage pest, almond moth (Cadra cautel...
Article
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Plant secondary metabolites are considered to be a rich source of bioactive compounds for the discovery and development of molecules for human health and crop protection. These metabolites were found effective, non-persistent, environmentally safe, target specific and an alternative to toxic synthetic drugs and pesticides. To identify the bioactive...
Article
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Parthenin, a sesquiterpene lactone of pseudoguaianolide type, is the representative secondary metabolite of the tropical weed Parthenium hysterophorus (Asteraceae). It accounts for a multitude of biological activities, including toxicity, allergenicity, allelopathy, and pharmacological aspects of the plant. Thus far, parthenin and its derivatives h...
Article
A series of chalcones (1–14) were synthesized, characterized (using IR and 1H NMR techniques), and evaluated with an objective to manage rice root-knot nematode (RRKN) (Meloidogyne graminicola) both under pluronic gel and field conditions. Out of these fourteen compounds, 1-(4-fluoro-phenyl)-3-phenyl-propenone (13) and 1,3-diphenyl-propenone (14) s...
Article
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Despite the emergence of novel biotechnological and biological solutions, agrochemicals continue to play an important role in crop protection. Fungicide resistance is becoming a major problem; numerous cases of fungicide resistance have occurred worldwide in the last decade, resulting in the loss of several fungicides. The discovery of new molecule...
Article
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A series of ferrocenyl chalcones using acetylferrocene with different aldehydes were synthesized and their in vitro evaluation against Meloidogyne incognita was reported. The present study was carried out in net house conditions, Division of Nematology, ICAR-IARI, during rabi 2018-19, the bioefficacy evaluation of most effective compounds, identifi...
Article
Full-text available
A series of ferrocenyl chalcones using acetylferrocene, with ferrocenyl group at the keto carbonyl group, and different aldehydes were synthesized and their bioefficacy evaluation was done against Sclerotium rolfsii, Alternaria solani and Meloidogyne incognita. In continuation of our quest for potent crop protection products, in the present study,...
Article
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Essential oils fromSyzygium aromaticum, Cymbopogon flexuosus and Cymbopogon martinii were isolated by hydrodistillation method and analysed by GC-FID and GC-MS. Eugenol (87.1%) and citral (69.4%), respectively were identified as major compounds in clove and lemongrass oils while geraniol (81.6%) and geranyl acetate (12.4%) in palmarosa oil. Essenti...
Article
This article describes citric acid cross-linked amphiphilic poly(ethylene oxide) (PEO) macroporous open cell polyester amphigel, optimally synthesized using response surface methodology by applying central composite design to screen significant reaction parameters for maximizing percent water sorption. The chemical structure of the amphigel was con...
Article
Controlled release (CR) nanoformulations of Mancozeb (Manganese-zinc double salt of N, N-bisdithiocarbamic acid), a protective fungicide, have been developed using poly (ethylene glycols) (PEGs) based functionalized amphiphilic copolymers and evaluated for the management of early blight in tomato. During the field experiment, it was observed that n...
Article
Full-text available
A new microwave method (MM) has been developed for the synthesis of a series of 16 substituted ferrocenyl chalcones using acetylferrocene (1) with different aldehydes (2a-2p) and comparing it with conventional method (CM). The synthesized compounds were characterized by various spectroscopic techniques viz IR, HR-MS, 1H NMR, and 13C NMR. The time r...
Article
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Bio-availability is major concern in delivery of dietary phytochemicals for better bio-efficacy. The reduced bio-availability of food bioactive compounds is evident due to degradation during human digestion process which involves liberation, absorption, distribution, metabolism and elimination. The bio-efficacy of any nutrient can be increased by i...
Article
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A series of 42 phenolic acid amides, synthesized using different phenolic acids (salicylic acid, 3-hydroxy cinnamic acid, p-coumaric acid, caffeic acid, ferulic acid, o-coumaric acid, cinnamic acid and amines (propyl amine, hexyl amine, heptyl amine, undecyl amine, hexadecyl amine, octadecyl amine) were screened for their insecticidal activities ag...
Article
Novel N-alkyl-N-[1-(5-fluoro-2-hydroxyphenyl)ethyl]amines and N-alkyl-N-[1-(3,5-dichloro-2-hydroxyphenyl)ethyl]amines were synthesized as new agricultural pests controlling agents. Novel halogenated Schiff bases derived secondary amines were screened for in vitro fungicidal bioassay by poison food technique and the results showed promising fungicid...
Article
Full-text available
Antibiotics are widely used agricultural input and their application amount is at least as great as the amount used by humans. The estimate of exact quantity of antibiotic use in global agriculture varies considerably more than 50000 tonnes annually. A wide range of antibiotics, having similar chemical structure with the antibiotics used for human...
Article
The investigation was carried out to standardize the harvesting stage for maximum oil and essential oil yield in Artemisia annua L. in the semi arid region of Gujarat. The experiment was laid out in randomized block design with seedlings planted at the age of six weeks and harvested at five different phonological stages.viz., early vegetative (Marc...
Chapter
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Pesticides play a crucial role in safeguarding agricultural produces from several biotic stresses such as insect's attacks, fungal and bacterial diseases, and rodents. Just like human, medicine pesticide applications also require various formulation strategies to deliver the bioactive substances to the target site. Pesticides were being formulated...
Article
Chemical analysis of hexane and ethyl acetate soluble fractions obtained from the rhizobacteria Pseudomonas jessenii strain R62 and Pseudomonas synxantha strain R81 was carried out using gas chromatography-mass spectrometry and their nematicidal activity was evaluated against root-knot nematode, Meloidogyne incognita second stage juveniles (J2). Re...
Article
Biopesticides are considered to be safe, target specific, biodegradable and eco-friendly. These, especially Azadirachta indica A. Juss. (neem) based biopesticides, are mainly used as emulsified concentrate (EC). There is growing interest in nano emulsions based on phytochemical mixtures due to their better efficacy compared to conventional biopesti...
Article
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Nardostachys jatamansi DC. (Valerianaceae) is an important plant used in Ayurveda, Homeopathy, local healthcare and modern medicine industries. The drug produces essential oil (Spikenard oil) on extraction which is the source of variety of medicinal and aromatic products. Drug was collected from natural populations during the month of October. Esse...
Article
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The yield and chemical composition of the seed oil of Celastrus paniculatus were determined by solvent extraction and gas chromatography-mass spectrometry. The yield of crude fatty oil was found to be 45.5% in the mature seeds on dry weight basis. Fourteen compounds, constituting 97.57% of the oil, were identified. The oil was rich in unsaturated f...
Article
Experiments were conducted on the farm and laboratory of ICAR-Directorate of Medicinal and Aromatic Plants Research (ICAR-DMAPR), Anand, Gujarat to determine the most effective treatment for rapid germination of Artemisia annua by subjecting the seeds to physical treatment by soaking in cold and warm water for 1, 2 and 4 hours (h) and 2, 4 and 6 mi...
Article
The composition of the essential oil isolated from the rhizomes of Zingiber zerumbet Smith was determined using GC and GC–MS. Zerumbone (74.82%), humulene (6.02%), and β-copaen-4α-ol (4.32%) were identified as major compounds. E-Bisabol-11-ol (4.32%), E-bisabol-11-ol (0.92%), β-sinensal (0.57%), and α-himachalene oxide (0.19) were reported for the...
Article
Full-text available
The essential oil composition of five elite Cymbopogon varieties (OD-19, Pragati, RRL-16, NLG-84) and a hybrid (CPK-25) and four new selections (LS-1 to LS-4) were determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The oil yield ranged from 0.31% to 1.0% with CPK-25 (1.0%) and LS-2 (0.95%) containing the highest...
Article
Full-text available
A new series of halogenated Schiff bases was synthesized by the condensation of 5-fluoro-2-hydroxy acetophenone and 3,5-dichloro-2-hydroxy acetophenone with different alkyl amines, namely propyl, pentyl, hexyl, heptyl, octyl, nonyl, dodecyl, tetradecyl, hexadecyl, and octadecyl amines, under microwave irradiation. Newly formed molecules were charac...
Article
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Rhizoctonia solani can infect plants belonging to > 32 families and 188 genera. This pathogen also causes major yield loss worldwide in many crops like: rice, green gram, cowpea, gram and groundnut, soybean, maize, jowar, wheat and bajra etc. Essential oils are natural, volatile complex terpenoid compounds characterized by a strong and specific odo...
Article
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Chemical composition of the essential oils of five Ocimum species namely Ocimum tenuiflorum syn Ocimum sanctum L. (green and purple), Ocimum kilimandscharicum Guerke, Ocimum viride Willd, Ocimum basilicum L. and Ocimum gratissimum L., obtained by a hydrodistillation was determined by GC and GC-MS. A total of one hundred three compounds were identif...
Article
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Mentha species are cultivated as industerial crops mainly in Uttar Pradesh and parts of Punjab for production of essential oil but not commerially cultivated in Gujarat. To promote cultivation of some Mentha species in the region, promising cultivars of Mentha arvensis L. (cv. Himalaya and cv. Kosi) and M. spicata L. (cv. MSS-5) were planted in exp...
Conference Paper
Background Rice is most widely consumed staple food for a large part of the world's human population and its production is largely concentrated in Asia. Fungal pathogen causes considerable potential yield loss of rice grains production during crop production due to lack of plant protection measures. Sheath blight disease, caused by Rhizoctonia sol...
Article
The yield and fatty oil components of the seed kernels of Annona squamosa Linn. (Family: Annonaceae) were determined by a solvent extraction method and gas chromatography--mass spectrometry (GC/MS). The seed kernels were found to contain about 22.2% of crude fatty oil on a dry weight basis. The crude fatty oil was converted into methyl esters and a...
Article
Full-text available
This study was conducted to determine the effect of Cephalotaxus griffithii needle essential oil (CGNO) on proliferation and migration of human cervical cancer (HCC) cells. CGNO treatment decreased the viability of all the tested HCC (HeLa, ME-180 and SiHa) cells. Morphological and DNA fragmentation analysis of CGNO-treated HeLa cells indicated the...
Article
Full-text available
The chemical compositions of the essential oil obtained by hydrodistillation method from the aerial parts of Anethum graveolens were analysed by GC/MS. Twelve compounds constituting 96.7% of the oil were identified. The main compounds were alpha-phellandrene (31.8%), apiole (15.3%), dill ether (13.2%), limonene (11.8%), geraniol (10.6%) and p-cyme...
Article
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Centrifugal Partition Chromatography coupled with Diode Array Detector (DAD) method was developed to isolate swertiamarin from the methanolic extract of the aerial parts of Enicostema axillare. A biphasic solvent system composed of chloroform-methanol-water (86:74:20, v/v) was used to separate ~20.0mg of swertiamarin from 1.0gm crude methanolic ext...
Article
Full-text available
This investigation was undertaken to identify the major secondary metabolite, produced by two Trichoderma harzianum strains (T-4 and T-5) with their antifungal activity against phytopathogenic fungi using poison food technique. The ethyl acetate extract was subjected to column chromatography using n-hexane, ethyl acetate and methanol gradually. Chr...
Article
Full-text available
The yield and fatty oil components of the seed kernels of Annona squamosa Linn. (Family: Annonaceae) were determined by a solvent extraction method and gas chromatography–mass spec-trometry (GC/MS). The seed kernels were found to contain about 22.2% of crude fatty oil on a dry weight basis. The crude fatty oil was converted into methyl esters and a...
Article
An experiment was conducted to work out the optimum spacing for obtaining maximum biomass, essential oil and artemisinin yields in antimalarial herb (Artemisia annua L.) in the semi-arid region of Gujarat. It was laid out in a randomized block design with 5 spacing treatments, viz. 30 cm × 45 cm, 30 cm × 60 cm, 45 cm × 45 cm, 45 cm × 60 cm and 60 c...
Chapter
Full-text available
Many phytochemical pesticides exhibiting broad spectrum of activity against pests and diseases have long been considered as attractive alternative to synthetic chemical pesticides as they are biodegradable, target specific, and pose no or less hazard to the environment or to human health. Although a large number of studies suggest that plant-based...
Article
Full-text available
The paper reports the Good Agricultural Practices (GAP) of Enicostema axillare (Lam.) A. Raynal(= Enicostemma littorale auct. non Blume). Details of the GAP which includes growing environment, soil type, propagation material, nursery technique, transplanting details, manure application, optimum spacing, Intercultural operations, harvest and post ha...
Data
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Manipur in a project mode to provide knowledge, technological information and trainings to the farmers, entrepreneurs and other peoples interested in the development of medicinal and aromatic plants sector in the state. The activities of the project were started from April 2008. Facilitation Centre is now fulfilling a critical gap of medicinal plan...
Data
Manipur in a project mode to provide knowledge, technological information and trainings to the farmers, entrepreneurs and other peoples interested in the development of medicinal and aromatic plants sector in the state. The activities of the project were started from April 2008. Facilitation Centre is now fulfilling a critical gap of medicinal plan...
Article
Full-text available
Chemical composition of the essential oils obtained from the aerial parts of Artemisia annua at vegetative, pre-bloom, bloom and post-bloom stages was determined using GC and GC/MS analysis. The yields of essential oil were 0.14%, 0.34%, 0.64% and 0.54% (w/w), respectively at different growth stages. A total of 67 compounds were identified. Oxygena...
Article
Full-text available
Chemical composition of the essential oils obtained from the aerial parts of Artemisia annua at vegetative, pre-bloom, bloom and post-bloom stages was determined using GC and GC/MS analysis. The yields of essential oil were 0.14%, 0.34%, 0.64% and 0.54% (w/w), respectively at different growth stages. A total of 67 compounds were identified. Oxygena...
Article
Full-text available
The essential oils obtained by hydrodistillation from the rhizomes and leaves of Curcuma leucorhiza Roxb. were analyzed by gas chromatography (GC) and GC/mass spectrometry (GC/MS) for the first time. A total of forty-nine compounds were identified in both oils. The main compounds in the rhizome and leaf oils were germacrone (9.6-19.7%), curdione (1...
Article
Full-text available
The chemical composition of essential oil obtained by hydrodistillation method from the rhizomes of Z. zerumbet var. darcyi was determined by GC and GC-MS. Thirty-three compounds, accounting for 93.6% of the oil were identified including twenty compounds in minor (0.1-0.6%) and eight in trace (<0.05%) amounts. The main compounds were zerumbone (69....
Article
Full-text available
The essential oils obtained by hydrodistillation from the fresh peels of Citrus macroptera Montr. and C. maxima (Burm.) Merr. were analyzed by GC and GC/MS. The yields of oil ranged from 0.53% in C. macroptera to 0.13% in C. maxima cultivar (white). Forty-seven compounds were identified in the oils with limonene (55.3-80.0%), dodecyl acrylate (2.2-...
Article
Full-text available
Mamejvo (Enicostemma axillare Raynal) is a perennial herb with diversified health benefits. It was found to be affected by a witches’ broom disease under the field conditions at Anand, Gujarat, India. Affected plants were 53.33% reduced in height due to shortened internodes, leading to typical witches’ broom symptoms. Flower size was reduced signif...