
Vipula R BataduwaarachchiUniversity of Colombo · Department of Pharmacology
Vipula R Bataduwaarachchi
MBBS, MD (Medicine), MRCP (UK) (Res), Eur Dip Res Med (HERMES) Pg Cert Med Edu
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24
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December 2015 - February 2017
Publications
Publications (24)
Epidemiological studies have shown high tuberculosis (TB) prevalence among chronic opioid users. Opioid receptors are found on multiple immune cells and immunomodulatory properties of opioids could be a contributory factor for ensuing immunosuppression and development or reactivation of TB. Toll-like receptors (TLR) mediate an immune response again...
Epidemiological studies have shown high tuberculosis (TB) prevalence among
chronic opioid users. Opioid receptors are found on multiple immune cells and
immunomodulatory properties of opioids could be a contributory factor for ensuing
immunosuppression and development or reactivation of TB. Toll-like receptors (TLR)
mediate an immune response again...
Bronchoscopy procedure is of key importance in making histological diagnosis in lung cancer as well as in the diagnosis of other infective, inflammatory and allergic lung diseases. National Hospital of Sri Lanka (NHSL) receives referrals from all parts of the country. Therefore, it is essential to maintain the best possible quality standards in the...
Breathing pattern disorders (BPD) are considered to be as a common respiratory manifestation interfering with day-to-day life of many people globally. It has got multiple causation and variable presentations often overlapping with other respiratory diseases like asthma as a comorbidly. In Sri Lanka, less attention is paid to identify and treat BPD...
Background: We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, for the treatment of patients admitted to hospital with COVID-19. Methods: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised wit...
Background
We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, for the treatment of patients admitted to hospital with COVID-19.
Methods
This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised with...
Objective:
To assess sex-based differences in the prevalence of risk factor, their management, and differences in the prognosis among acute coronary syndrome (ACS) in Sri Lanka.
Methods:
Patients diagnosed with ACS were recruited from hospitals throughout the island. The Joint European Societies guidelines were used to assess recommended targets...
Objective. To assess sex-based differences in the prevalence of risk factor, their management, and differences in the prognosis among acute coronary syndrome (ACS) in Sri Lanka. Methods. Patients diagnosed with ACS were recruited from hospitals throughout the island. e Joint European Societies guidelines were used to assess recommended targets for...
Background: Unwanted medicines are defined as expired, unused, damaged or contaminated pharmaceutical products. Improper disposal of unwanted medicines leads to many health and environmental hazards. The World Health Organisation recommends that unwanted medicines should always be disposed properly. The main objective of this study was to assess th...
Background: Medication waste has major implications on human and animal health, environmental safety and the health economy. Low and middle income countries have paid less attention to proper medication waste disposal at household and community level. This is the first baseline assessment on medication waste disposal practices among the general pub...
Background
Ischaemic heart disease is the leading cause of in-hospital mortality in Sri Lanka. Acute Coronary Syndrome Sri Lanka Audit Project (ACSSLAP) is the first national clinical-audit project that evaluated patient characteristics, clinical outcomes and care provided by state-sector hospitals.
Methods
ACSSLAP prospectively evaluated acute ca...
Medication waste is synonymous with pharmaceutical waste, unused or expired medicines. Improper disposal of medication waste leads to serious personal and environmental health hazards. There were no established medication waste management programmes in most of the developing countries including Asia. Presence of unique socioeconomic problems in the...
Paraneoplastic limbic encephalitis is an uncommon association of common malignancies such as small cell lung carcinoma, testicular teratoma, and breast carcinoma. The nonspecific nature of the clinical presentation, lack of freely available diagnostic markers, and requirement for advanced imaging techniques pose a great challenge in the diagnosis o...
Granulomatosis with polyangiitis is a rare multisystemic autoimmune disorder predominantly affecting the upper and lower respiratory tracts and the kidneys, and rarely affecting other organ systems. Tuberculosis can mimic the presentation of granulomatosis with polyangiitis, and both can occur simultaneously in the same patient. Here we report what...
Introduction:
Tuberculosis is a progressive and disabling infection predominantly seen in low-income and middle-income countries. Immunocompromised patients are at a higher risk of contracting tuberculosis than the healthy population. The presentation may also be atypical, leading to delay in diagnosis. We report the first case of tuberculous cere...
Introduction:
Melioidosis is an emerging infection in South Asia. It has a spectrum of presentation causing many difficulties in early diagnosis and the control of infection. Here we report a rare case of melioidosis causing an inguinal sinus in a Sri Lankan male.
Case presentation:
This 54‐year‐old male had recurrent admissions to hospital with mu...
Crohn's disease is a relapsing, systemic inflammatory disease affecting the gastrointestinal tract with associated extraintestinal manifestations and immune disorders. Among the few cases reported, the association of Crohn's disease with polymyositis varies in its complexity and severity. We report here the first known case of inflammatory polymyos...
Anatomically, it is difficult to give a systematic description of the superficial branch of the radial nerve (SBRN). Our aim was to describe the exact relationship of the SBRN to fixed bony points of radial styloid and Lister's tubercle, and to the cephalic vein. We also compared our data with other international studies.
The study was a descriptiv...
Intravenous access is one of the most commonly performed invasive procedures in the clinical practice, during which the improper practice of the aseptic precautions could lead to fatal healthcare associated infections. A descriptive cross sectional study was conducted to assess the compliance with aseptic precautions during intravenous access and t...