Vipin Singh

Vipin Singh
Banaras Hindu University | BHU · Institute of Medical Sciences(Department of Biochemistry)

Master of Life Sciences

About

4
Publications
283
Reads
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10
Citations
Citations since 2017
4 Research Items
10 Citations
20172018201920202021202220230246810
20172018201920202021202220230246810
20172018201920202021202220230246810
20172018201920202021202220230246810

Publications

Publications (4)
Article
Necroptosis is a form of programmed cell death executed by receptor-interacting serine/threonine protein kinase 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like (MLKL). Platelets are circulating cells that play central roles in haemostasis and pathological thrombosis. In this study we demonstrate seminal contribution of MLKL in transformation...
Article
Platelet mitochondria possess remarkable plasticity for oxidation of energy substrates, where metabolic dependency on glucose or fatty acids is higher than glutamine. Since platelets metabolize nearly the entire pool of glucose to lactate rather than fluxing through mitochondrial tricarboxylic acid cycle, we posit that majority of mitochondrial ATP...
Article
Full-text available
Background: Notch signaling dictates cell fate decisions in mammalian cells including megakaryocytes. Existence of functional Notch signaling in enucleate platelets remains elusive. Methods: Transcripts/peptides of Notch1 and Delta-like ligand (DLL)-4 were detected in platelets isolated from human blood by RT-qPCR, Western analysis and flow cytomet...

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