Vincenza Spera

Vincenza Spera
Università di Pisa | UNIPI · Department of Clinical and Experimental Medicine

Doctor of Medicine

About

20
Publications
1,965
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163
Citations
Additional affiliations
September 2020 - present
Cantonal Sociopsychiatric Organisation
Position
  • Medico Capoclinica

Publications

Publications (20)
Chapter
Substance Use Disorders (SUDs) are often associated with Attention-Deficit Hyperactivity Disorder (ADHD) in adult populations due to multiple neurobiological, genetic, and psychosocial risk factors. This chapter provides a picture of the clinical aspects of adults with both ADHD and SUDs at treatment entry into a Dual Disorder Unit introducing the...
Article
Full-text available
Background: Transcranial photobiomodulation (tPBM) has recently emerged as a potential cognitive enhancement technique and clinical treatment for various neuropsychiatric and neurodegenerative disorders by delivering invisible near-infrared light to the scalp and increasing energy metabolism in the brain. Objective: We assessed whether transcran...
Article
Full-text available
While the association between adult Attention Deficit/Hyperactivity Disorder (A-ADHD) and Substance Use Disorders (SUDs) has been widely explored, less attention has been dedicated to the various substance use variants. In a previous paper, we identified two variants: type 1 (use of stimulants/alcohol) and type 2 (use of cannabinoids). In this stud...
Article
The main aim of this study was to examine the body of knowledge on the prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in “high-risk” children whose parents are diagnosed with ADHD. This knowledge could aid early identification for children presenting with ADHD symptoms at a young age. We conducted a systematic search of the literatur...
Article
The purpose of the study was to assess the prevalence and clinical correlates of Delayed Sleep Phase Disorder (DSPD) in adults with Attention-Deficit/Hyperactivity Disorder. Participants were 102 adults (Female= 27), aged 18-65 (mean age= 28.2 years), with ADHD diagnosed in adulthood. ADHD and DSPD diagnosis were made according to DSM-5 criteria. A...
Article
Full-text available
Background: While a large amount of medical literature has explored the association between Attention Deficit/Hyperactivity Disorder (ADHD) and Substance Use Disorders (SUDs), less attention has been dedicated to the typologies of SUD and their relationships with ADHD-specific symptomatology and general psychopathology in dual disorder patients....
Preprint
Full-text available
Objective Our objective was to assess whether transcranial photobiomodulation (tPBM) with near-infrared light (NIR) shows modulatory effects on cerebral electrical activity through electroencephalogram (EEG) and cerebral blood flow (CBF). Background tPBM has emerged as a novel intervention for several neuropsychiatric conditions due to its neuropr...
Article
Objective: Our aim was to test the anxiolytic effect of transcranial photobiomodulation (t-PBM) with near-infrared light (NIR) in subjects suffering from generalized anxiety disorder (GAD). Background: t-PBM with NIR is an experimental, noninvasive treatment for mood and anxiety disorders. Preliminary evidence indicates a potential anxiolytic effe...
Article
Objectives: So far, no specific medication has been approved by international drug regulatory agencies for the treatment of cocaine use disorder (CoUD). The reward deficiency syndrome (dysphoric-depressive) was originally described as an outcome after detoxification; it is now considered to be one of the possible routes to relapsing behavior. Mater...
Article
Background. Using the SCL90 checklist, we previously showed that a cluster of five psychopathological symptoms could be found in Heroin Use Disorder patients. This aggregation demonstrated a high degree of stability, as it proved to be independent of addiction-related conditions such as treatment chosen, intoxication status, and presence of psychia...
Article
Full-text available
Background Over-standard methadone doses are generally needed in the treatment of heroin use disorder (HUD) patients that display concomitant high-severity psychopathological symptomatology. A flexible dosing regimen may lead to higher retention rates in dual disorder (DD), as we demonstrated in bipolar 1 HUD patients, leading to outcomes that are...
Article
Background: In the USA, emergency room (ER) visits for Substance Use Disorders with or without Dual Diagnosis become more frequent in the last decade. This is particularly true of opioid overdoses and opioid withdrawal symptomatology, and also of psychotic episodes related to the use of cannabinoids and stimulants. Methods: To verify the degree to...
Article
Full-text available
Introduction: In this study, we used a symptomatology checklist (SCL-90) to substantiate the hypothesis that Substance Use Disorder (SUD) has its own five-dimensional psychopathology. The aim of the present study was to test whether this psychopathology can be differentiated from other psychiatric psychopathological dimensions (such as obesity). Me...
Article
Introduction In the last decade, the comprehension of affective temperaments has helped us to outline the boundaries of mood disorders, and to expand our knowledge of nosographic areas other than those of affectivity, even if affectivity is closely related to them. In the field of substance use disorders, the temperamental profile of heroin addicts...
Article
Full-text available
Osteoporosis (OP) and fragility fractures (FFx) are a known comorbidity in patients with systemic lupus erythematosus (SLE). This work aimed at evaluating (1) the prevalence of OP and FFx in a cohort of SLE and (2) the risk factors associated with both OP and FFx. The following data were collected from clinical charts: age, sex, menopausal status (...
Article
Background Osteoporosis (OP) and subsequent fragility fractures (FFx) are a common comorbidity in patients with Systemic Lupus Erythematosus (SLE). A chronic therapy with glucocorticoids (GC) is one of the main risk for their development. Due to the severe impairment of the quality of life they could cause, prevention and treatment of OP is a centr...

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