Vincent Gremeaux

• M.D, Ph.D
• Head of Department at French Institute of Health and Medical Research

The sport of triathlon has evolved to become a discipline comprising races of different lengths and formats. It has also undergone significant growth in popularity and exposure with several variations in format from the classic swim – bike – run combination attracting significant television and media coverage. Since 2021 an original and unique form...

Understanding the influence of running-induced acute fatigue on the homeostasis of the body is essential to mitigate the adverse effects and optimize positive adaptations to training. Fatigue is a multifactorial phenomenon, which influences biomechanical, physiological, and psychological facets. This work aimed to assess the evolution of these thre...

Purpose: To present training load (TL) and heart-rate variability (HRV) in an elite sprinter monitored before, during, and after a COVID-19 infection until successful return to performance. Methods: TL, subjective morning fatigue (MF), and supine HRV were monitored during a 12-week period. Results: During a high-TL period (training camp), MF a...

Background: Gross efficiency in cycling (GE) seems correlated with lower-body strength. This study investigated GE at four different pedaling rates and its relationship with an isokinetic strength test in bike messengers (BM) and experienced athletes non-bike messengers (NBM). Methods: Eight BM and eight NBM completed a maximal incremental test...

La cryothérapie du corps entier se pratique principalement soit par immersion en eau froide, soit en chambre de cryothérapie. Pratiquée depuis l’Antiquité et considérée comme une méthode « naturelle », la cryothérapie tend à attirer de plus en plus d’adeptes. Des effets bénéfiques pour la santé ont été décrits dans la littérature. Néanmoins, l’inte...

Background: Obesity is associated with an accelerate cognitive decline. However, aerobic fitness (peak V̇ O2) has a protective effect on cognition in older adults but no study investigated this effect in obese individuals. The present study aimed at 1) comparing cognitive function in lower-fit (LoFit) and higher-fit (HiFit) obese individuals compar...

BACKGROUND Fatigability measured and derived parameters are commonly used in research and clinical contexts to characterize performance during isokinetic fatigue protocols. The fatigability measured parameters are the best repetition, the total and the partial sums while the fatigability derived parameters are ratios and formula-based parameters....

Introduction/Background Stroke survivors are encouraged to participate in regular physical activity (PA). However, the vast majority of patients do not practice PA as recommended and numerous “barriers” prevent the patient from getting back to a physically active lifestyle. Objective To develop and validate a self-reported questionnaire assessing...

Background: An efficient cardiac rehabilitation programme (CRP) can improve the functional ability of patients after acute coronary syndrome (ACS). Objective: To examine the effect of a CRP on parasympathetic reactivation and heart rate recovery (HRR) measured after a 6-min walk test (6MWT), and correlation with 6MWT distance and well-being afte...

Objective: To develop and validate a self-report questionnaire to measure barriers to regular physical activity (PA) in patients with stable coronary artery disease (CAD). Methods: Phase 1: 17 patients completed a semi-structured interview. After grouping and reformulating the reported barriers, their pertinence was reevaluated by the patients....

Simplifying health messages can be puzzling. French media1 recently criticised WHO’s 2016 physical activity recommendations,2 based on the data published by Kyu and colleagues in The BMJ .3 Two years ago, they ran a very different headline: “Sitting kills more people than tobacco,” based on a commentary published in 2009.4 The …

Introduction Gait impairment appears as one of the most common and disabling symptoms in people with multiple sclerosis (PwMS). Few symptomatic treatments exist at the progressive phase of the disease. Fampridine (4-aminopyridine) an inhibitor of the potassium channels has demonstrated a positive effect on gait speed in PwMS with gait disturbance....

Objectives: There is ambiguity concerning the walk tests available for functional assessment of coronary patients, particularly for the walking speed. This study explores the psychometric properties of two walking tests, based on fixed-distance tests, at comfortable and fast velocity, in stabilized patients at the end of a cardiac rehabilitation p...

Letter Re: Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013 http://www.bmj.com/content/354/bmj.i3857/rr-9

Objective: We aimed to compare prolonged hypotension following moderate-intensity continuous exercise (MICE), high-intensity interval exercise (HIIE) in dry land or HIIE in immersed condition, using 24-h ambulatory blood pressure monitoring (ABPM). Design and method: Forty-two individuals (Table 1) suffering from hypertension or with a baseline...

Objective The proportion of healthy years lost due to disease rapidly increased with age. It is well established that regular physical activity is an efficient strategy for successful aging. However, less than 50% are able to achieve the 150 min of moderate and vigorous physical activity (MVPA) per week. The prescription of physical activity for ol...

Background: Isometric strengthening has been rarely studied in patients with coronary heart disease (CHD), mainly because of possible potential side effects and lack of appropriate and reliable devices. Objective: We aimed to compare 2 different modes of resistance training, an isometric mode with the Huber Motion Lab (HML) and traditional strength...

OBJECTIVE: We aimed to compare prolonged hypotension following moderate-intensity continuous exercise (MICE), high-intensity interval exercise (HIIE) in dry land or HIIE in immersed condition, using 24-h ambulatory blood pressure monitoring (ABPM). DESIGN AND METHOD: Forty-two individuals (Table 1) suffering from hypertension or with a baseline blo...

Exercise training, associated with therapeutic education, is the main axis of cardiac rehabilitation (CR) programs. The aim of this study was to review the literature for descriptions of the various assessments of exercise tolerance used to prescribe exercise intensity during CR. A secondary objective was to attempt to formulate a rational practice...

The purpose of the study was to determine whether total work measured during a high intensity isokinetic fatigue test (TWFAT) could be considered as a valid measure of anaerobic work capacity (AWC), such as determined by total work measured during a Wingate Anaerobic Test (TWWAnT). Twenty welltrained cyclists performed 2 randomly ordered sessions i...

The effectiveness of regular exercise in decreasing both systolic and diastolic blood pressure (BP) is well-established. Our purpose was to assess the impact of both subject and physical activity program characteristics on ambulatory BP through a meta-analysis of the existing literature. Three databases (PubMed, Embase, Web of Science) were searche...

We aimed to compare blood pressure (BP) responses following moderate-intensity continuous exercise (MICE), high-intensity interval exercise (HIIE) in dry land or HIIE in immersed condition, using 24-h ambulatory blood pressure monitoring. Forty-two individuals (65±7 years, 52% men) with a baseline BP ≥130/85 mm Hg (systolic/diastolic, SBP/DBP), wer...

The purpose of this study was to determine whether the mechanical contribution of ankle muscles in the upright stance differed among young adults (YA) (n=10, age: ~24.3), elderly non-fallers (ENF) (n=12, age: ~77.3) and elderly fallers (EF) (n=20, age: ~80.7). Torque and electromyographic (EMG) activity were recorded on the triceps surae and tibial...

De façon à prévenir la perte d’efficacité de la prévention secondaire à distance de la fin de la réadaptation cardiaque, une expérimentation d’une consultation multidisciplinaire de soutien en éducation thérapeutique est proposée par une unité hospitalière de réadaptation cardiaque. Les différents aspects du mode de vie sont abordés : activité phys...

Type de document : lettre à l'éditeur

Objective Isokinetic tests regularly contribute to the assessment of muscle performance. However, to evaluate an athlete who mainly uses the lactic anaerobic metabolism to perform or in specific pathological contexts, fatigue-resistance protocol could be complementary to short maximal strength evaluation. Although the reproducibility of the protoco...

The health benefits of 150 min a week of moderate-to-vigorous-intensity physical activity (MVPA) in older adults, as currently recommended, are well established, but the suggested dose in older adults is often not reached. We aimed to determine whether a lower dose of MVPA was effective in reducing mortality, in participants older than 60 years. Th...

Background: The aims of this work were (1) to compare cerebral oxygenation-perfusion (COP), central hemodynamics, and peak oxygen uptake (V˙o2peak) in heart transplant recipients (HTRs) vs age-matched healthy controls (AMHCs) during exercise and recovery and (2) to study the relationships between COP, central hemodynamics, and V˙o2peak in HTRs and...

While physical activity (PA) is recommended for high blood pressure management, the level of PA practice of hypertensive patients remains unclear. We aimed to assess the association between the level of both PA and blood pressure of individuals consulting in 9 hypertension specialist centres. Eighty-five hypertensive patients were included (59±14ye...

Objective: Regular physical activity (PA) is a recommended component of treatment of hypertensive subjects, but its prescription is rare and most often insufficient. In addition, the PA level of hypertensive subjects remains unclear, even as methods of evaluation are growing up (subjective method using self-questionnaires or objective method using...

Evaluation of the clinical effectiveness and safety of a new custom-made valgus knee brace (OdrA) in medial knee osteoarthritis (OA) in terms of pain and secondary symptoms. Open-label prospective study of patients with symptomatic medial knee OA with clinical evaluation at 6 and 52 weeks (W6, W52). We systematically assessed pain on a visual analo...

AbstractBackground The main French language scales evaluating functioning after lower-limb amputation have not undergone exhaustive psychometric validation. Objective A transcultural validation of the Special Interest Group in Amputee Medicine (SIGAM) mobility grades questionnaire, with 21 closed questions, as an administered questionnaire. Methods...

To assess the relationship between selected measures (the slope and average performance) obtained during a high intensity isokinetic fatigue test of the knee (FAT) and relevant measures of anaerobic and aerobic capacities. 20 well-trained cyclists performed 3 randomly ordered sessions involving a FAT consisting in 30 reciprocal maximal concentric c...

Heart rate (HR) at the ventilatory threshold (VT) is often used to prescribe exercise intensity in cardiac rehabilitation. Some studies have reported no significant difference between HR at VT and HR measured at the end of a 6-min walk test (6-MWT) in cardiac patients. The aim of this work was to assess the potential equivalence between those param...

The aim of this study was to determine whether 45 mins of transcutaneous electrical nerve stimulation before exercise could delay pain onset and increase walking distance in peripheral artery disease patients. After a baseline assessment of the walking velocity that led to pain after 300 m, 15 peripheral artery disease patients underwent four exerc...

http://authors.elsevier.com/a/1RPlw_OBYI6oBE The aim of this study was to determine a set of measures for the evaluation of balance in patients suffering from hip osteoarthritis that were both reliable and responsive to change. Three groups of subjects; Healthy, hip osteoarthritis patients without surgery, and hip osteoarthritis with surgery (pre...

The eccentric (ECC) training, in spite of its potential interest (slightest request of the cardiorespiratory system) compared with the concentric (CON) training, is not applied during the rehabilitation of the chronic heart failure (CHF). The main reasons are the difficulty personalizing the ECC exercises by avoiding the muscle complications and th...

Heart rate (HR) at the ventilatory threshold (VT) is often used to prescribe exercise intensity in cardiac rehabilitation. Some studies have reported no significant difference between HR at VT and HR measured at the end of a 6-min walk test (6-MWT) in cardiac patients. The aim of this work was to assess the potential equivalence between those param...

It is well known that center of pressure (CoP) displacement correlates negatively with the maximal isometric torque (MIT) of ankle muscles. This relationship has never been investigated in elderly fallers (EF). The purpose of this study was thus to analyze the relationship between the MIT of ankle muscles and CoP displacement in upright stance in a...

Objective: To assess the effect of a 4-month high-intensity interval training programme on cognitive functioning, cerebral oxygenation, central haemodynamic and cardiometabolic parameters and aerobic capacity in obese patients. Methods: Cognitive functioning, cerebral oxygenation, central haemodynamic, cardiometabolic and exercise para-meters we...

Objectives To describe fear-avoidance beliefs about low back pain (LBP) in a sample of teaching general practitioners (TGPs) and to investigate the impact on following the guidelines for LBP.MethodsA sample of 112 French TGPs were contacted to complete a self-administered questionnaire including socio-demographic and professional data, personal his...

Objective: The aim of this study was to investigate safety, tolerance, relative exercise intensity, and muscle substrate oxidation during sessions performed on a Huber Motion Lab in coronary heart disease patients. Design: After an assessment of Vo2 peak, 20 coronary heart disease patients participated in two different exercises performed in ran...

Objective To develop a new predictive model of maximal heart rate based on two walking tests at different speeds (comfortable and brisk walking) as an alternative to a cardiopulmonary exercise test during cardiac rehabilitation. Design Evaluation of a clinical assessment tool. Setting A Cardiac Rehabilitation Department in France. Subjects A tot...

Background In 3D gait analysis, the knee joint is usually expressed using the Eulerian description. It consists in breaking down the motion between the articulating bones of the knee into three rotations around three axes: flexion/extension, abduction/adduction and internal/external rotation. However, the definition of these axes is prone to error,...

High blood pressure is a frequent pathology with many cardiovascular complications. As highlighted in guidelines, the therapeutic management of hypertension relies on non-pharmacological measures, which are diet and regular physical activity, but both patients and physicians are reluctant to physical activity prescription. To acquire the conviction...

La rehabilitación en la arteriopatía de los miembros inferiores se basa en programas personalizados que asocian readaptación al esfuerzo y educación terapéutica. Aumenta las capacidades físicas, sobre todo la distancia de la marcha, permite reanudar las actividades, reduce los factores de riesgo y mejora los frecuentes trastornos del estado de ánim...

Introduction: The aim of this work was to carry out a review of the literature on the clinical and paraclinical evaluation of bladder sensory (BS) to better understand BS disorders in nonneurological patients. Methods: Thirty-three articles were selected from the Medline(®) Database between 1992 and 2012 using the following key words: "sensory/s...

High blood pressure is a frequent pathology with many cardiovascular complications. As highlighted in guidelines, the therapeutic management of hypertension relies on non-pharmacological measures, which are diet and regular physical activity, but both patients and physicians are reluctant to physical activity prescription. To acquire the conviction...

Objective: The aim of this study was to investigate safety, tolerance, relative exercise intensity, and muscle substrate oxidation during sessions performed on a Huber Motion Lab in coronary heart disease patients. Design: After an assessment of V˙o2 peak, 20 coronary heart disease patients participated in two different exercises performed in rando...

This study aims were: 1) to assess forearm blood flow (FBF) and muscle oxygen consumption (mVO2) repeatability assessed with near-infra red spectroscopy (NIRS) during venous occlusions (VO) in middle aged healthy subjects and patients with stable coronary heart disease (CHD), 2) to assess the agreement between mVO2 calculated from NIRS signals duri...

Introduction The aim of this work was to carry out a review of the literature on the clinical and paraclinical evaluation of bladder sensory (BS) to better understand BS disorders in nonneurological patients. Methods Thirty-three articles were selected from the Medline® Database between 1992 and 2012 using the following key words: “sensory/sensiti...

Walk tests, principally the six-minute walk test (6mWT), constitute a safe, useful submaximal tool for exercise tolerance testing in cardiac rehabilitation (CR). The 6mWT result reflects functional status, walking autonomy and efficacy of CR on walking endurance, which is more pronounced in patients with low functional capacity (heart failure - car...

Purpose: The aims of this study were: 1) to study the impact of a combined long-term lifestyle and high-intensity interval training (HIIT) intervention on blood pressure (BP) in patients with abdominal obesity; 2) To document BP reduction responses according to the European Society of Hypertension BP classification. Methods: 105 patients with abdom...

Objectives. — To document the profession of teachers in adapted physical activity (APA) in reha- bilitation centre (SSR) and suggest possible improvements to better structure the profession and the management in these SSR. News. — APA teachers involved in the three main areas of support provided by the SSR (exer- cise training, therapeutic educatio...

Background: QT dispersion (QTd) is a marker of myocardial electrical instability, and is increased in metabolic syndrome (MetS). Moderate intensity continuous exercise (MICE) training was shown to improve QTd in MetS patients. Objectives: To describe long-term effects of MICE and high-intensity interval exercise training (HIIT) on QTd parameters...

La sédentarité reste un facteur de risque cardiovasculaire majeur. Les bénéfices de l’activité physique (AP) sont largement admis en prévention primaire et secondaire, et font l’objet de recommandations régulièrement remises à jour par les sociétés savantes internationales. Il persiste néanmoins quelques points de controverse, principalement concer...

Lepers, Romuald | Stapley, Paul J. | Cattagni, Thomas | Gremeaux, Vincent | Knechtle, Beat

Objectifs Évaluer l’impact à moyen terme d’ateliers d’éducation sur la lombalgie (L) dans le contexte d’une cure thermale sur : les croyances de peur et d’évitement, l’incapacité, la douleur et la satisfaction. Méthodes Une étude randomisée prospective, avec périodes d’inclusion alternées d’un mois (alternate month design) incluant 360 individus s...