Vinay J Shukla

• M.Sc. (Analytical Chemistry) Ph.D.
• Pharmaceutical Chemist at Gujarat Ayurved University

Leaves of Olax scandens (Roxb.) are consumed as vegetables in some parts of India. The present study was carried out to evaluate the phytochemical content, nutritional value and antioxidant activity of Olax scandens (Roxb.) leaves following standard procedures. Qualitative analysis of the leaf powder reveals that carbohydrates, alkaloids, saponin,...

Introduction: Haritaki (Terminalia chebula Retz.) of Combretaceae family is well known drug often used in Ayurvedic therapeutics. Ayurvedic texts advised to consider the fruits that sink in stable water in therapeutics. As tannin is an important constituent of Haritaki, an attempt has been made to determine tannin content and other differences in a...

Aims: Balachaturbhadra Avaleha has been prepared and studied for its pharmacognosy and pharmaceutical parameters. The adopted formulation is based on Balachaturbhadra Churna of Chakradatta. Though Balachaturbhadra Churna has significant efficacy in pediatric disorders it has a few difficulties as a medicament like non acceptability by children, low...

A Simple, monetary, reproducible, precise High performance thin layer chromatography (HPTLC) method was used to determine the content of Oleanolic acid in methanolic extract of Sapindus trifoliatus Linn. using Toluene: Ethyl acetate: Formic acid (7:2:1) as mobile phase. Quantification was performed by ƛ= 529 nm. The validated method showed linear r...

Importance of topical formulations in therapeutics has been noticed by the ancient seers. In suitable cases, they preferred topical medicaments along with internal medicaments. Kushtha taila is one such formulations of topical application advocated to be applied after incision of umbilical cord. Though the formulation is useful; its form poses cert...

Introduction Sthaulyahara Ghana Vati (SHGV) is a polyherbal formulation, which is indicated in Sthualya (obesity) in Vaidhyasara sangraha. There are few clinical works carried out on this medicine, but no any researchers had evaluated this formulation for its quality control (QC) parameters. Pharmacopeia standards for this formulation are also not...

Background Herbo-mineral-metallic formulations are an inseparable part of the Ayurveda system of traditional medicine. Hridayarnava Rasa (HR) is a preparation containing metals like copper, sulphur, and mercury in processed forms and other herbs that do not produce toxic effects and adverse drug reactions when taken in appropriate dosage. Ayurveda...

Context In Ayurveda, Yashtimadhu is being used as one of the healing drugs in the management of different kinds of wounds. The preparations made from Yashtimadhu such as Churna , Ghrita , Taila , and Malahar are being practiced in wound care unit to treat different kinds of wounds as local application. Multiple treatment modalities are mentioned in...

Background: Cannabis (Bhanga) has been extensively explored in research for therapeutic benefits. Out of 80+ phyto-cannabinoid detected till date; out of which Tetrahydrocannabinol (THC), Cannabidiol (CBD) and Cannabinol (CBN) are therapeutically important. Psychotropic concern about cannabis is a majorly attributed to THC presence. For reducing in...

The traditional drug manufacturing process involves numerous qualitative attributes that directly impact product quality. The Process Analytical Technology approach considers that to enhance process control, identifying critical process parameters and critical quality attributes that affect the manufacturing process is very much necessary. The Ayur...

Objective: The Areca catechu L. is a tropical fruit, which is also called betel nut and is widely distributed in different parts of the world. Areca catechu L is used for various treatment aliments in the form of various preparations especially in powdered form and it used extensively in Ayurveda to treat Mukhavikara, Aruchi, Yonishaithilya, Shveta...

Rasnadi basti is mainly indicated for the Vataj disorders i.e., Vibandha, Anaha, Aruchi, Shoola, Vandhyatva, Pradara, Prameha, Yonidosha, Pandu, etc. It is having properties like Sarvaroganivarana, Shukrajanana, Vrushya, and Pumsavana Parama. Acharya Siddhinandan Mishra has mentioned the effectiveness of Rasnadi basti in the treatment of Vandhyatva...

BACKGROUND Kantakari Avaleha (KA) is a semisolid herbal drugs preparation recommended for various diseases like Hikka (hiccup), Kasa (cough), Shvasha (dyspnoea/asthma), and Shoola (colicky pain) in Sharangdhara Samhita. In this study, KA was slightly modified (after an experiment of classical and intermediate batches) by adding sugar and honey 1.5...

Background: PCOS is the most common syndrome among reproductive age as well as adolescence girls. The prevalence in India of polycystic ovary syndrome (PCOS) in women of reproductive age ranges between 9.13% to 36%. It is an endocrinal disorder in which the pathology establishes from the alteration of HPO axis. In Ayurvedic texts, eight type of...

Phytochemicals of the plants have significant role in drug development for treatment of human diseases. Majority population in Africa, Asia and Latin America use plant based medicines. Kigelia pinnata DC. is a reputed African folklore drug and now abundantly found throughout India. It belongs to the family Bignoniaceae and used in different disease...

Background: Byttneria herbacea Roxb., family Sterculiaceae, commonly called as 'Samarakhai' in local Odia language, is one of the reputed folklore medicinal herb. Its roots, leaves, and whole plant parts are reported for traditional use in the management of dysentery, sores, cuts, wounds, cholera, leucorrhoea, fractures, and sprains. Aim: The ai...

Although some perceive infertility as a quality-of-life issue, it is in fact a disease with increasing public health concerns. Infertility has been declared as global health issue by world health organization. Anovulation comprises 30-40% part and also probably a major cause of female infertility which interfere woman’s chances to conceive. Referen...

Adolescence" as the time period between 10 and 19 years of life characterized by critical physical and psychological changes leading to adulthood. Menstruation is one of the most important changes during adolescent years. Menstrual disorders are frequent among adolescent girls as they are closely coupled with the processes involved in the pubertal...

BACKGROUND Good prenatal care includes the mother’s nutrition and healthy habits during pregnancy. Failure to supply adequate nutrition can lead to fetal malnutrition. Critical analysis of the dietetic guidelines mentioned in Ayurveda classics for pregnancy reveals that the recommended diet has Rasayana (rejuvenation) properties, which covers the a...

Sidhhamantra Nighantu is one such unique lexicon which has a chapter named as Tridoshaghna Varga which enlists the drugs which pacify one, two or all the three Doshas i.e., Vata, Pitta and Kapha. Drugs pacifying all the three Doshas are unique in their Rasa Panchaka in terms of specific combination of Rasa, Guna, Virya and Vipaka. The Tridoshaghna...

Introduction Quality standardization and maintenance of these standards is the need of the hour in this era which is showing growing demand for traditional medicines. Although Abhayadi Gutika (AG) is an important formulation in Ayurvedic pharmacopeia, it lacks scientific documentation. Aims The aim was to study organoleptic, microscopic, physicoch...

Background Ayurveda is age-old medical system, practiced in India. Ayurveda medicines are being prepared from natural sources like herbs, animal products, and minerals. Ancient Ayurveda scholars have mentioned various pharmaceutical procedures to make it bioavailable. They also mentioned about various parameters to control the quality and standardi...

Background: Ayurveda has a holistic aim to keep mankind healthy. Due to the growing acceptance of herbal drugs worldwide, it is important to provide data on quality, safety, and efficacy. Ayurveda prescribes metals, minerals, and herbomineral formulations under the heading of Rasa Shastra in addition to herbal medicines only. Manufacturing procedur...

BACKGROUND Rasayana Vati (RV) is an herbal preparation containing Amalaki ( Phyllanthus emblica L.), Haridra ( Curcuma longa L.), and Guduchi ( Tinospora cordifolia (Willd.) Miers) in an equal proportion. It is a useful formulation in Beejadushtijanya Pandu (thalassemia). Till date, analytical data are not available for this herbal preparation. The...

Chirabilvadi Yoga is a combination of four drugs Chirabilva, Arjuna, Jyotishmati and Kakanasa in powder form, each of these ingredients has solid base of previous experimental studies for their individual analgesic activity. Bhavana (trituration) is an important Samskara (process) mentioned in Ayurvedic classics by which drug may be made very poten...

Introduction: Blepharis is the largest genus which includes 126 species distributed among three subgenera (Blepharis, Ebracteata Volllesen, and Acanthodium). Seeds of Utingan (Blepharis maderaspatensis) have been useful in Mutrakruccha (dysuria), Svasa (Cough), Kasa (Asthma), as a Vajikaran (Aphrodisiac), and eye disorder. Aim and Objective: To eva...

Introduction: Therapeutic efficacy of Bhasma gets altered and its therapeutic arena increases with increase in number of Puta, simultaneously increase in number of Puta increase cost, time for manufacture. Classical texts favour sensory analysis for inprocess as well as product standard especially for Bhasma dosage forms. Objective: Present study w...

Background: Atalantia monophylla DC. (Syn. Limonia monophylla L.), family Rutaceae, root and stem have been reported for their use in rheumatism, arthritis, antidote to snake-bite, cough, allergies, skin diseases and as an antidote to snake-bite through ethnomedicinal claims. Present study reports a details pharmacognostic and preliminary physioche...

Menopausal syndrome is a grouping of signs and symptoms associated with menopause. In Ayurveda, menopause is referred to as 'Rajonivrutti' (and menopausal syndrome as Rajonivruttianubandhaja vyadhies). Menopause's long-term risks include osteoporosis, cardiac problems, and Alzheimer's disease. Aims and objective: To study the Pharmacognostic, Phyto...

Securinega leucopyrus (Willd.) Muell, is a thorny large shrub belonging to the family Euphorbiaceae. In Ayurveda it has a lot of potential medicinal uses. It has been described by the medico-ethnobatanist as a wonderful drug for the treatment of wound healing. The aim of present study was to establish standardization parameters of male and female p...

Modified Rasayana Yoga is an Ayurvedic polyherbal formulation specially made for Diabetic retinopathy. The modified Rasayana Yoga containing Haritaki, Amalaki, Vibhitaki, Haridra, Guduchi, Musta, Yastimadhu and Vasa. Diabetic retinopathy (DR) is leading cause for the blindness and one of the most important complication seen in patients with Diabete...

Objective: The aim of the present work was to assess the total alkaloid content (TAC), total tannin content (TTC), total phenolic content (TPC), and total flavonoid content (TFC) of crude methanolic extract of root, stem, and leaf of Leea macrophylla Roxb. ex Hornem. which is a medicinally important plant belonging to the family Vitaceae and used e...

Celosia argentea Linn. is a leading leafy vegetable of Nigerian country and India. It is herb, ornamental plant which belongs to family Amaranthaceae also having medicinal use in antidiabetic, anti-inflammatory, antioxidant, anti-bacterial, antiapoptosis etc. For proper methodical evaluation, authentication, macroscopy, microscopy, physicochemical...

Introduction Root and fruits of Bhumi Udumbara (Ficus semicordata Buch.-Ham. ex Sm.) are traditionally used in the treatment of aphthous complaints, leprosy, headache, abdominal diseases, bladder ailments, visceral obstruction, and various disorders. Aim Present study reports the microscopic including powder microscopy, physiochemical and prelimin...

Introduction: Different types of Snehapaka have been mentioned in Sarangdhar Samhita such as Mrudu Paka, Madhyama Paka, Khara Paka, Dagdha Paka, Ama Paka, and Gandha Paka. Further, different uses of sneha according to its paka had been mentioned in which Madhyama Paka and Khara Paka are stated to be used for internal (Pana) and external (Abhyang),...

Spectroscopic Analysis of Lagos spinach- seed

Sensory evaluation is a quantitative science in which numerical data are collected to establish lawful and specific relationships between product characteristics and human perception. Among the sensory methods available, Triangle test method was adopted. The purpose of this study was to differentiate Madhyama Paka and Khara Paka Katupila Taila with...

Introduction: Shodhana (method of purification) is preliminary process that helps in eliminating possible physical or chemical blemishes from raw material and making them suitable for therapeutic application. Chitraka (Plumbago zeylanica Linn.) is well known drug in Ayurveda, which is also gaining its attention in world market. Root of this plant i...

Background:Medicinal plants are important part of Indian system of medicine. Medicinal plants are used for preparation of millions of preventive and curative medicines. Adansonia digitata is also one of such plants having great medicinal value. Objective: Adansonia digitata is a well-known plant in the traditional medicinal system and it has been e...

Introduction: Ficus semicordata Buch.-Ham. ex Sm. (Syn. Ficus cunia Buch.- Ham. ex Roxb.) of family Moraceae, is one of the plants used by the folklore of Odisha for medicinal purposes. Traditional healers use the plant’s leaf, stem, stem bark, root, and fruit to treat jaundice, stomach disorders, skin diseases, and other ailments. The present re...

Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical...

Introduction: Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body. This taila is described as exceptionally beneficial for improving the strength of hands. Before a human trial it is essential to evaluate the quality and authenticity of the trial drug, Stand...

Erythroxylum moonii Hochr. is a shrub or small tree in family Erythroxylaceae and folklore claims report the use of its leaves in the treatment of helminthiasis. Aim: Hence, present study aims to evaluate the pharmacognostic and analytical characters including HPTLC of its leaves. Methods: E. moonii fresh and powdered leaves were explored for the m...

Abhraka Bhasma comes under Maharasa Varga and after Parada second position hold by Abhraka. From centuries, Acharayas have been using Abhraka Bhasma incorporated in vast number of formulations. There are so many methods and medias is used for Shodhana,Marana process of Abhraka ,in present study for Abhraka Shodhana, Godugdha is used as Shodhana med...

Chitraka Haritaki Avaleha is a Leha Kalpana (semisolid preparation of drugs, prepared with addition of jaggery and boiled with prescribed decoction) specifically indicated for oral use in treatment of nasal disorders in Ayurveda. It is also indicated in various disorders like Kshaya (Pthisis), Kasa (Cough), Peenasa (Chronic rhinitis/sinusitis), Kri...

Katupila - Securinega leucopyrus (willd) Muell. is ethnobotanic medicine, whose leaves are proven to exhibit wound healing property through in vitro, in vivo experimental studies and clinical study along with other properties like anti inflammatory, antioxidant etc. Present study was aimed to develop suitable Ayurvedic dosage form which can value a...

National seminar organized by RAV at Vigyan Bhavan, New Delhi.

Background: Triphala is one of the most easily available and commonly used medicine which contains fine powder of three fruits viz. Terminalia chebula Retz. (Haritaki), Terminalia bellerica Roxb. (Bibhitaki) and Embilica officinalis Gaertn. (Amalaki) and is indicated as one of the drugs for management of disorders of Kapha and Meda. Due to bitter a...

AIM The aim of this study was to evaluate phytochemical constituent and high-performance thin-layer chromatography (HPTLC) analysis of Ashawattha Kandatwaka (the outer portion of stem bark) Churna (powder). INTRODUCTION Ashawattha Kandatwaka Churna is a major constituent of numerous ayurvedic formulations. The plant has possessed their various pha...

Introduction Vata ( Ficus benghalensis Linn.) is a sacred medicinal plant since Vedic times. It spread all over by its hanging or supporting roots, hence called as Vata . Aims The aim was to study the macro- and microscopic characters, physiochemical and high-performance thin-layer chromatography (HPTLC) profile of Vata ( F. benghalensis Linn.) Ja...

Background: Durvadi Ghrita is a Sneha Kalpana which is claimed to be effective in Madhumehajanya Timira (Diabetic Retinopathy). In present study, it has been used for Nasya. Objective: Present study was planned to look out on herbal drugs used in the preparation of Durvadi Ghrita and standardization of drug by pharmacognostical and physicochemical...

The benign tumor that originates in the uterus it is called a uterine fibroid. The growths are typically benign, or noncancerous. The cause of fibroids is unknown. According to the Office on Women’s Health, up to 80 percent Trusted Source of women have them by the age of 50. However, most women don’t have any symptoms and may never know they have f...

Introduction: Dhanyamla is a medicated liquid preparation produced by fermentation process of various grains. Dhanyamla is cold at perception by its nature as it is a sour liquid and Ayurvedic classics opine that amla rasa is of cold nature if used externally. It is commonly used for management of Diabetic Polyneuropathy which commonly presents wit...

Introduction- Patoladi Kwath is herbal compound formulation mentioned in Chakradatta Amlapitta Rogadhikara. It contains Patola, Dhanyak, Sunthi and Musta. Whereas another indications of the formulation are Mandagni, Jwara, Chhardi, Daha, Shoola, Ama and diseases caused by provocation of Tridosha. Materials & Methods- Patoladi Kwath was subjected to...

Introduction: Erandamuladi Kwatha is mentioned in Ayurveda classics as a therapeutic formulation of Basti mainly to treat Trika-prishta Shoola (low back ache). The most common disorder which affects the movement of leg particularly in the productive period of life is low backache. Erandamuladi Kwatha used in Basti contains 15 drugs in which most of...

Introduction: Erandamuladi Niruha Basti is mentioned in Charaka Samhita which is indicated in Trika, Prishta Shoola (low back ache) and acts as Maruta Nigraha. Low backache is the most common ailment in today’s busy life. Erandamuladi Kalka used in Basti contains 9 drugs in which most of the drugs are having Ushna Veerya and are Shoolahara in natur...

Quality control of Ayurvedic medicines though being the need of the hour, is an arduous task. As Ayurveda encompasses the use of drug as a whole which leads to generation of a complex matrix. In such a scenario, selective and sensitive sophisticated analytical tools alone cannot serve the purpose. Besides, the ancient science of medicine is sensory...

Background: Ayurveda emphasizes that different parts of plants (both organized and unorganized) should be collected on a certain season to get their better yield and therapeutic value. In general, Kshira (latex) should be collected in Sharada rutu (autumn season). However, the latex of Snuhi has been stated to be collected at Shishiranta (end of wi...

The stem and stem bark of Pittamari (Cipadessa baccifera (Roth.) Miq of family Meliaceae) are traditionally has been reported for its use in treating psoriasis, chicken pox, fever etc. Present study reports the pharmacognostical and analytical study of its stem and stem bark as per standard procedures. The result shows, externally, the stem is brow...

BACKGROUND: Byttneria herbacea Roxb., an extrapharmacopoeial plant of Ayurveda, locally known as Samarakhai by tribal people of Odisha, belongs to the family Sterculiaceae. The roots of B. herbacea is traditionally claimed to be used in the management of wounds, fractures, swellings, gynecological disorders, diarrhea, cuts, ulcers, and others. Alth...

Background Covid-19 is the disease caused by SARS-CoV2, it was identified in Wuhan, China, in 2019. It then extended across the globe and was termed as a pandemic in 2020. Though research work on its vaccine and drugs are carried out across the globe, it is even necessary to look over it through alternative sciences. Objective The objective of thi...

Background: Adansonia digitata L. belong to family Bombacaceae is a well-known plant in the traditional medicinal system and it has been employed for the treatment of various diseases. Aim and Objectives: This study was aimed to establish the total phenolic content and antioxidant potential of A. digitata along with the HPTLC study to identify pote...

Takrarishta is a well-practiced Sandhana preparation (fermented preparation) of Ayurveda. It has wide therapeutic indications like Dyspepsia, Abdominal lump, Piles, etc. But yet its quality assessment has not been standardised. In present study its preliminary phytochemical screening along with physicochemical evaluations has been performed. As the...

Background: Punarnava Guggulu is a polyherbal formulation mentioned in Bhaishajya Ratnavali containing various Ayurvedic medicinal drugs and specially indicated for the treatment of Amavata and Vatarakta. For assurance of quality of herbal compounds pharmacognostical and pharmaceutical analysis should be done. Methods: Punarnava Guggulu was subject...

Introduction: Bhui dumri one of the folklore plants of Odisha, is identified as Ficus semicordata Buch.-Ham. ex Sm.(Syn. Ficus cunia Buch.-Ham. ex Roxb.) of family Moraceae. The leaves of the plant are used, by the traditional healers, in the treatment of jaundice, stomach disorders, wound healing, scabies, leprosy, indigestion, liver ailment and s...

ABSTARCT Ayurveda has the potential with dealing natural and holistic approach of treatment and may be proven more effective as the conservative management proposed for Mootraghata (BPH). Due to deranged function of Vata, particularly Apana Vata perturbed with Kapha Dosha which is the prime causative factor to produce the Mootraghata. Hence the lin...

Introduction: Shodhana (purification) is the process by which one can remove the impurity or toxicity of the raw drug and make the drug suitable for therapeutic purpose. Chitraka (Plumbago zeylanica Linn.) is well known drug in Ayurveda and root of this plant is being used for therapeutic purpose and requires purification before used as a medicine...

India has one of the most diverse cultural traditions associated with the use of medicinal plants and this knowledge is accessible from thousands of medical texts and manuscripts. The substances having medicinal value have been used extensively for treating numerous disease conditions. Herbs being easily available to human beings have been explor...

Vaiatarana basti is a preparation mentioned for management of Gridhrasi by Vangasena and has Guda, Amlika, Taila and Go-payah as its ingredients. It is having Vata and Kapha samana properties and will help in normalizing doshas responsible for the disease condition. Gridhrasi comes under vatavyadhi and shoola (pain) is its major symptom. A pharmaco...

Rasna Guggulu is a preparation mentioned for management of Gridhrasi by Chakradutta and has Rasna, Guggulu and Ghrita as its ingredients. It is having Ushna Virya, Vata hara as well as Vata Kapha samana properties so as to encounter the disease condition. Gridhrasi is a disease where shoola (pain) is a major symptom and which comes under vatavyadhi...

Background: Standardization of herbal formulation is needed in order to assess of quality of drug. Maintaining the quality standard of a polyherbal formulation is a difficult task. In the era of increasing demand for traditional medicines, maintaining quality standards is the need of the hour. Aim: The present work was carried out to standardize th...

Objectives: Pittosporum floribundum Wight & Arn. (Pittosporaceae) has been associated with many therapeutic claims, especially for its ethnomedicinal and economical uses. In this review, an extensive literature survey was carried out to compile information available about its medicinal uses, phytochemistry and pharmacological properties. Materials...

Background: Leea macrophylla Roxb. ex Hornem. (Vitaceae) is one of the wild edible plants used traditionally to treat urinary disorders, inflammatory diseases, wound, rheumatism and cancer etc. Though various parts of the plant have been used for therapeutic purpose, stem of the plant has not been studied for its Pharmacognostical and phytochemical...

Abstract: INTRODUCTION: Ayurveda recommends standardization of different useful parts of herbal drug, either organized or unorganized, starting from its collection. The latex of snuhi is said to be collected at the end of Shishira ritu. This article highlights the result of scientific study on effect of season on collection of latex of Euphorbia ca...

Introduction: Ayurveda recommends standardization of different useful parts of herbal drug, either organized or unorganized, starting from its collection. The latex of snuhi is said to be collected at the end of Shishira ritu. This article highlights the result of scientific study on effect of season on collection of latex of Euphorbia caducifolia...

Background: Latex of Euphorbia caducifolia Haines. (Euphorbiaceae), botanical source of Rakta Snuhi, a caustic irritant, is being used in different Ayurvedic therapeutics, after proper processing (Shodhana) in some specific media. Shodhana of Snuhi latex with Chincha-Patra Swarasa (juice of tamarind leaves) using Raudra Yantra (instrument/pot kept...

Background: Pittosporum floribundum is an ethnomedicinal plant which has a numerous number of medicinal claims and it hasn’t been explored thoroughly. Various parts of plant used medicinally such as used in skin disorder, leprosy, etc. Aims: To explore different qualitative, quantitative and antifungal aspect of Pittosporum floribundum. Materials a...