Vijaya Bhaskar Reddy A

Vijaya Bhaskar Reddy A
Universiti Teknologi PETRONAS | UTP · Department of Chemical Engineering

PhD

About

66
Publications
23,125
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Introduction
Vijaya Bhaskar Reddy completed his PhD in Chemistry from Sri Venkateswara University, India and currently working as Postdoctoral Researcher in Department of Chemical Engineering, Universiti Teknologi PETRONAS. My major research fields includes 'Analytical Method Development for Phrmaceutcals; Wastewater Treatment; Development of Ionic Liquid Polymers for CO2 Capture and Separation; Development of Green and Low-Cost Adsorbents for Pollutants Removal"
Additional affiliations
January 2018 - present
Universiti Teknologi PETRONAS
Position
  • PostDoc Position
June 2014 - August 2017
Universiti Teknologi Malaysia
Position
  • PostDoc Position
July 2010 - March 2014
Sri Venkateswara University
Position
  • Researcher

Publications

Publications (66)
Article
Full-text available
The presence of hazardous dyes in wastewater cause disastrous effects on living organisms and the environment. The conventional technologies for the remediation of dyes from water have several bottlenecks such as high cost and complex operation. This review aims to present a comprehensive outlook of various bio-sorbents that are identified and succ...
Article
Coumarin derivatives are important class of natural plant metabolites that offer variety of biological activities. They can also be derived synthetically, and a wide variety of synthetic coumarin derivatives (azoles, sulfonyl, furan, pyrazole etc) have shown promising anticancer, antitumor and anti-proliferative activities. Coumarin derivatives are...
Chapter
With the rapid escalation of industrialization toward development, the quality of water has become a serious concern. The heavy metals in water present serious life-threatening effects. Of the variety of conventional methods to treat heavy metal-contaminated water, adsorption is the most popular method due to its low cost, simplicity, and efficienc...
Chapter
Ionic liquids are salt-like compounds that remain in a liquid state at low temperatures and that have their melting points below 100°C. After the discovery of the first ionic liquid, ethylammonium nitrate, by Paul Walden in 1914, it took almost a century for ionic liquids to gain researchers’ attention. In the past two decades, ionic liquids have b...
Chapter
The remarkable features of ionic liquid (IL)-based surfactants including high surface/interfacial activity, low critical micelle concentration, and better solubilization have validated them as excellent alternatives for oil spill remediation over the existing commercial surfactants. Considering the significance of IL-based surfactants in recent yea...
Article
Full-text available
Salicylic acid is an important component in cosmetics and skincare products and is widely found in aqueous streams as waste material. The present study reported the extraction of salicylic acid from wastewaters using a new technique termed as ‘ionic liquid-based emulsion liquid membrane’ (IL-ELM). Ionic liquids were introduced as carriers in IL-ELM...
Article
Full-text available
Development of ionic liquid-based emulsion membranes (ILEMs) has emerged as potential alternatives to organic solvent-based emulsion membranes for the extraction and recovery of biologically active compounds from aqueous streams. Hence, present study aims to develop novel ILEMs for the removal of bioactive lactic acid (LA) from aqueous streams usin...
Article
The well-known toxicity of conventional chemical oil spill dispersants demands the development of alternative and environmentally friendly dispersant formulations. Therefore, in the present study we have developed a pair of less toxic and green dispersants by combining lactonic sophorolipid (LS) biosurfactant individually with choline myristate and...
Chapter
Releasing of toxic metals (Pb, Cd, Hg, Zn, Cr, etc.) and organic compounds (dyes, PAHs, volatile organic compounds, etc.) into the environment has become main resources of environmental pollution which affects the human being and other organism life directly or indirectly. These inorganic and organic compounds have adverse effect on living being ev...
Chapter
The concern towards the increasing challenges in water treatment technologies made researchers towards significant innovations in recent years. The incorporation of nanotechnology in this field obtained remarkable results due to its exceptional properties. Among them, carbon nanocomposites (CNCs) have proved to be promising materials due to their l...
Chapter
The rapid growth of population, industrialization and urbanization tends to deteriorate the quality of available water bodies. This scenario became vulnerable to the environment, and it has alarmed the community to resolve this issue. A large variety of pollutants occur from the above activities, specifically heavy metals creating severe toxicity t...
Chapter
Heavy metals are high atomic weight elements that consist five times higher density than water. The widespread use of heavy metals in scientific, agricultural, domestic, industrial, and medical applications accelerated their distribution into water bodies through the environment. The extreme toxicity of heavy metals and their adverse effects on hum...
Conference Paper
Ionic liquids (ILs) technology has been emerged as most prominent approach for the CO2 capture, which is an important phenomena in oil & natural gas industry during the gas sweetening process. The remarkable performance of IL polymers for the CO2 capture provided new opportunities to upgrade this technology in recent years. Therefore, in the presen...
Conference Paper
The concern towards the increasing challenges of sustainable agriculture made the researchers towards significant technological development and innovations in recent years. In particular, Nanotechnology offers potential solutions to improve agricultural production assuring sustainability. The incorporation of nanotechnology as a means of nano pesti...
Article
Monomeric ionic liquids (ILs), ionic liquid polymers (ILPs) and IL-based composites have emerged as potential materials for CO2 capture owing to their exceptional intrinsic physical solubility of CO2. This study reports the development of novel IL polymer materials incorporating CO2-philic tunable nanopores and their subsequent utilization for CO2...
Article
Formulations based on ionic liquids (ILs) have emerged as potential alternatives to conventional dispersants for remediating the effect of oil spills. However, the performance of such IL formulations is greatly affected by various environmental factors. The present study developed a model that correlates the wave-mixing energy, temperature and sali...
Article
Polychlorinated biphenyls (PCBs) are ubiquitous anthropogenic pollutants of major environmental concern. They remain in the environment and disturb the whole ecosystem. Considering the severe toxicity of PCBs on human health and global ecosystem, researchers developed several analytical procedures for the quantification of PCBs from different sourc...
Article
The application of chemical dispersants in marine oil spill remediation is comprehensively reported across the globe. But, the augmented toxicity and poor biodegradability of reported chemical dispersants have created necessity for their replacement with the bio-based green dispersants. Therefore, in the present study, we have synthesized five ioni...
Chapter
The importance of medicinal products originated from the plant materials has greatly increased in recent years. Among the different bioactive natural products, flavonoids are crucial compounds and are represented by over 8000 varieties. These flavonoid substances are found largely in the foods of plant sources, and they are subdivided into 13 categ...
Article
Full-text available
A sensitive and stability indicating liquid chromatography – tandem mass spectrophotometry method is developed for the simultaneous detection and quantification of 3-(1-piperazinyl)-1,2-benzisothiazole and 4-chloro-1,2-benzisothiazole potential treated as possible genotoxic impurities of lurasidone. The method utilizes Hypersil BDS C18 column (50 m...
Article
Ionic liquids (ILs)based surfactants have been emerged as attractive alternatives to the conventional surfactants owing to their tailor-made and eco-friendly properties. Therefore, present study described the synthesis of nine new fatty amino acids based IL surfactants utilizing lauroyl sarcosinate anion and pyrrolidinium, imidazolium, pyridinium,...
Article
Full-text available
Among the different ways to capture carbon dioxide (CO2), ionic liquid technology is one of the prominent approaches and gained the interest of researchers to improve this technology from time to time. In this study, we have prepared and characterized a novel ionic liquid polymer composite with zeolite and tested its efficiency to capture CO2. The...
Article
Polychlorinated biphenyls (PCBs) are a class of synthetic organic compounds containing carbon, hydrogen and chlorine atoms. They have been used in various industrial and commercial applications owing to their high boiling points, non-flammability, chemical stability and insulating properties. Also, PCBs are exceptionally stable and prevail in the e...
Article
In the present study a sensitive and fully validated liquid chromatography‐mass spectrometry method was developed for the quantification of three potential genotoxic impurities in rabeprazole drug substance. The separation was achieved on Symmetry C18 column (100 × 4.6 mm, 3.5 μm) using 0.1% formic acid in water as mobile phase A, and acetonitrile...
Article
Full-text available
A rapid and highly sensitive capillary electrophoresis method was developed combining on-line and off-line sample enrichment techniques that are capable to determine six widely used pharmaceuticals, viz. amoxicillin, carbamazepine, diclofenac, indomethacin, ibuprofen, and paracetamol from various food samples. A new sample preconcentration techniqu...
Article
An extremely sensitive and simple gas chromatography with mass spectrometry method was developed and completely validated for the analysis of five process related impurities viz., 4-hydroxy-l-phenylglycine, 4-hydroxyphenylacetonitrile, 4-hydroxyphenylacetic acid, methyl-4-hydroxyphenylacetate and 2-[4-{(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propox...
Article
Full-text available
This study describes the ability of conventional water treatment plants towards the removal of non-targeted new emerging pollutants (NEPs) by optimizing the variables such as pH and polyaluminium chloride (PAC), activated carbon, and chlorine (Cl2) concentrations. Gas chromatography-mass spectrometry (GC-MS) was used for the separation and quantifi...
Article
Full-text available
BackgroundA simple hydrothermal process was applied to synthesize the doped TiO2 particles with different concentrations as well as different metal ions (Mn, Ce and La). Methods The synthesis of Mn-doped-TiO2 nanoparticles was done by using a hydrothermal method from hydrolysis of titanium tetrachloride in aqueous solution. The photocatalytic activ...
Article
Full-text available
Drug discovery is a highly complicated, tedious and potentially rewarding approach associated with great risk. Pharmaceutical companies literally spend millions of dollars to produce a single successful drug. The drug discovery process also need strict compliance to the directions on manufacturing and testing of new drug standards before their rele...
Article
Full-text available
A sensitive and selective gas chromatography with mass spectrometry method was developed for the simultaneous determination of three organophosphorus pesticides, namely, chlorpyrifos, malathion and diazinon in three different food commodities (milk, apples and drinking water) employing solid-phase extraction for sample pretreatment. Pesticide extra...
Article
Full-text available
A sensitive ultra high performance liquid chromatography with tandem mass spectrometry method was developed for the simultaneous determination of darunavir, ritonavir and tenofovir in human plasma. Sample preparation involved a simple liquid-liquid extraction using 200 μL of human plasma extracted with methyl tert-butyl ether for three analytes and...
Article
Full-text available
This study investigated the rate of chlorpyrifos degradation with different carboxymethyl cellulose (CMC) stabilized and unstabilized iron-based nanoparticles viz. CMC-Fe0, CMC-Fe0/Ag and Fe0under different concentrations of chlorpyrifos. FT-IR and SEM analysis indicated that CMC molecules were adsorbed to nanoparticles through the carboxylate (COO...
Article
Full-text available
Synthetic biology (SB) is primarily an application-focused field attempting to develop and apply a systematic engineering approach to the design and construction of new biological systems and cells at the genetic level. It is a new area of biological research that integrates science and engineering with an aim to design and construct novel and usef...
Article
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Potential genotoxic impurities in pharmaceuticals at trace levels are of increasing concern to both pharmaceutical industries and regulatory agencies due to their possibility for human carcinogenesis. Molecular functional groups that render starting materials and synthetic intermediates as reactive building blocks for small molecules may also be re...
Article
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A selective and sensitive liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed for the quantitative determination of 1-(3-chloropropyl)-4- (3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone. The method provided excellent sensitivity at a typical target analyte level of <0.1 ppm, when the API s...
Article
Full-text available
Impurity profiling is now receiving critical attention from regulatory authorities. For trace level quantification of potential genotoxic impurities (PGIs), conventional analytical techniques like high-performance liquid chromatography (HPLC) and gas chromatography (GC) are inadequate; consequently, there is a great need to apply hyphenated analyti...
Article
Full-text available
The detection and quantification of potential genotoxic impurities (PGIs) play an important role in the pharmaceutical industry. The industry needs highly selective and sensitive analytical methods for trace level quantification of these PGIs in drug substances. A sensitive and stability indicating LC-MS/MS method was developed for the simultaneou...
Article
Full-text available
A stability indicating gradient reverse phase UPLC-MS/MS method was developed and validated for the simultaneous determination of three phenol impurities in ritonavir drug substance. The chromatographic separation was performed on Acquity UPLC BEH C18 column (100mm×2.1mm, 1.7μm) using gradient elution of 0.05% ammonia in methanol and 5.0mM ammonium...
Article
Full-text available
Combination of asenapine with valproic acid received regulatory approval for acute treatment of schizophrenia and maniac episodes of bipolar disorders. A simple LC–MS/MS method was developed and validated for simultaneous quantification of asenapine and valproic acid in human plasma. Internal standards were added to 300 μL of plasma sample prior to...
Article
Full-text available
The present investigation reports on the tolerance efficiency of Brassica Juncea (Indian mustard) against hexavalent Chromium (Cr (VI)) in the presence of zero valent nanoiron (ZVNI). The effect of farmyard manure (FYM), a natural organic matter used as an amendment on Cr (VI) detoxification was also studied. The seeds of Brassica Juncea are plante...
Article
A sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for simultaneous determination of urapidil and aripiprazole in human plasma. A simple liquid-liquid extraction with ethyl acetate was used for the sample preparation. Chromatographic separation was achieved on a Phenomenex C18 (4.6...
Article
Full-text available
The pivotal task of pharmaceutical industry is to separate and quantify the potential genotoxic impurities (PGIs) rising from the process of drug production. For trace level quantification of these PGIs we need to develop sensitive and selective analytical methods. APP, NPA, NPP and MNA have been highlighted as PGIs in zolmitriptan. A sensitive and...
Article
Full-text available
Chromium is an important industrial metal used in various products and processes but at the same time causing lethal environmental hazards. Remediation of Cr-contaminated soils poses both technological and economic challenges, as conventional methods are often too expensive and difficult to operate. Zero-valent iron particles at nanoscale are propos...
Article
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2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one has been highlighted as a potential genotoxic impurity in irbesartan. A sensitive LC-MS/MS method was developed and validated for the determination of 2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one in irbesartan. Good separation between 2-N-butyl-4-spirocyclopentane-2-imidazoline-5-one and irbesa...
Article
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Chromium is one of the toxic heavy metals which needs ample attention in terms of soil and environmental degradation. Among the heavy metals and their toxicity, chromium toxicity was well studied by the researchers with the corresponding remedial measures. In the present review paper, the occurrence, transformation, in different environments and th...
Article
Full-text available
Degradation of the insecticide chlorpyrifos in contaminated soils was investigated using laboratory synthesized zero-valent nano iron (ZVNI) particles. e synthesized ZVNI particles were characterized as nanoscale sized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). e zero-valent state (Fe 0) of iron was con�rmed...
Article
Full-text available
Liquid state lipase enzyme sensor was used for the detection of Carbophenothion and Dibrom organophosphorus pesticides and the electrochemical behavior of both the pesticides was studied. The developed enzymatic method is based on in situ generation of p-Nitrophenol by lipase enzymatic hydrolysis of p-Nitrophenyl Acetate substrate. The electrochemi...
Article
Full-text available
Nanotechnology is an emerging science that has shown potential applications in solving current problems involving water quality. Nanomaterials are highly reactive, have a large surface area compared to their mass and can easily capture other particles. Hence nanotechnology is also used as an environmental technology to protect the environment throu...
Article
Full-text available
A sensitive and selective liquid chromatographic-tandem mass spectrometric (LC/MS/MS) method was developed and validated for the trace analysis (>1ppm level) of 2-chloromethyl-3,4-dimethoxy pyridine hydrochloride a genotoxic impurity in pantoprazole sodium drug substances. LC/MS/MS analysis of 2-chloromethyl-3,4-dimethoxy pyridine hydrochloride was...
Article
Full-text available
Chitosan-stabilized Fe 0 nanoparticles (CS-Fe 0) and unstabilized Fe 0 nanoparticles synthesized in ethanol–water mixed system (EW-Fe 0) and were tested for degradation of chlorpyrifos in aqueous solution. Fourier transform infrared (FTIR) study suggested that nitrogen and oxygen atoms are the binding sites for chitosan on iron which was accountabl...