Victorien Tamègnon Dougnon

Victorien Tamègnon Dougnon
University of Abomey-Calavi | UAC · Polytechnic School of Abomey-Calavy (EPAC)

PhD
Targeting Antimicrobial Resistance surveillance and the use of medicinal plants as a great response from green pharmacy

About

315
Publications
152,539
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Introduction
Dr Victorien Tamègnon DOUGNON is Senior Lecturer in Microbiology at University of Abomey-Calavi, in Benin. He is involved, through his work, in the fight against antimicrobial resistance in Africa, especially with endogenous knowledge. He has established many strong scientific networks around the world to make his country a better place to live without infectious diseases. Early career researcher, he founded a strong research lab with a TWAS grant in 2017 (www.e-urmapha.com).
Additional affiliations
December 2013 - January 2016
University of Abomey-Calavi
Position
  • Lecturer/ Researcher in Microbiology and Applications
December 2013 - present
University of Abomey-Calavi
Position
  • Lecturer
Description
  • General Microbiology, Medical Microbiology, Applied Bacteriology, Food Hygiene and Risks Management, Research Methodology, Animal Experimentation in Health
December 2012 - present
University of Abomey-Calavi
Position
  • Lecturer/Researcher
Education
August 2005 - October 2011
University of Abomey-Calavi
Field of study
  • Biomedical Sciences

Publications

Publications (315)
Article
Full-text available
This study aims to evaluate the bacteriological, chemical, and toxicological quality of hospital effluents in Benin. Eighteen (18) samples were collected from the south and north of Benin, and poles were set up. Bacteriological analysis was carried out according to the French National Organization for Standardization (AFNOR) standard. Identificatio...
Article
Contexte La méningite bactérienne est une inflammation des méninges causée principalement par trois espèces bactériennes Neisseria meningitidis, Streptococcus pneumoniae et Haemophilus influenzae qui sont transmises par les sécrétions nasopharyngées émises par les porteurs. La méningite est un problème de santé publique au Bénin, comme dans tous le...
Article
Contexte Cette étude vise à étudier les caractéristiques épidémiologiques et géographiques des sérogroupes du méningocoque quatre ans après l'introduction du vaccin conjugué contre le méningocoque du sérogroupe A. Méthodes Il s'agit d'une étude prospective, descriptive et analytique, qui s'est déroulée de 2016 à 2018. Des échantillons de liquide c...
Article
The aquatic environment as a hotspot for the transfer of antibiotic resistance to humans and animals. Several reviews have put together research efforts on the presence and distribution of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in food, hospital settings, and even in aquatic environment. However, these reports ar...
Article
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The search for new bioactive molecules with antifungal properties to combat resistance to classical antifungals represents a great challenge. This study aimed to explore the virulence factors and resistance profile of Candida species isolated from urine samples in Benin and the in vitro efficacy of organic extracts of Cyanthillium cinereum (L.) H.R...
Article
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This study aimed to provide data on the subacute toxicity and fetotoxicity of aqueous and hydroethanolic extracts of Daniellia oliveri (Rolfe) Hutch. & Dalziel, Anacardium occidentale L., Diospyros mespiliformis Hochst. ex A. DC., Khaya senegalensis (Desv.) A. Juss., Ocimum gratissimum L., Vernonia amygdalina Delile, Pterocarpus erinaceus Poir., an...
Article
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Background Africa has a rich and diverse flora that people use for their food and health needs. This study aims to explore the possibility of using aqueous and/or ethanolic extracts of Alchornea cordifolia leaves as an alternative in the fight against multi-resistant bacteria responsible for gastritis and urinary tract infections. Results The resu...
Article
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Despite the worldwide success of the introduction of human immunodeficiency virus (HIV) testing and treatment with antiretroviral drugs, HIV remains a real public health problem. Vertical mother-to-child transmission is a form responsible for many cases of new infections. The objective of the study is to carry out an inventory of mother-to-child tr...
Article
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The present study aims to identify the emergence of Methicillin-resistant Staphylococcus aureus, S. aureus resistant to vancomycin and to investigate the presence of Mec A, Van A and Van B genes among Staphylococcus strains isolated from hospital environment. For each type of sample, surface of beds, recyclable material, boxes of rodar, floor and d...
Conference Paper
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11:00 Welcome Remarks Dr. M. Oladoyin Odubanjo Executive Secretary, the Nigerian Academy of Science (NAS) 11:05 Opening Remarks Professor Ekanem Braide FAS President, NAS 11:15 Goodwill message from the Nigerian Young Academy Dr. Muhammed Ibrahim President, NYA 11:20 Brief Introduction of Panelists Professor Olanike Adeyemo FAS – Moderator Editor-i...
Article
Full-text available
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the sca...
Article
Full-text available
Species A Rotaviruses (RVA) still play a major role in causing acute diarrhea in children under five years old worldwide. Currently, an 11-gene classification system is used to designate the full genotypic constellations of circulating strains. Viral proteins and non-structural proteins in the order VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5/...
Article
Full-text available
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the sca...
Article
Full-text available
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the sca...
Article
Full-text available
Acalypha wilkesiana Müll. & Arg., Lantana camara L., Ocimum gratissimum L., Pteleopsis suberosa Engl. Diels sont quatre des plantes médicinales les plus utilisées dans le traitement des candidoses au Bénin. L'objectif de la présente étude était de comparer la composition chimique, la teneur en polyphénol, l'activité anti radicalaire et la toxicité...
Article
Full-text available
Background: Nosocomial infections are a real public health problem due to the involvement of Multi-Resistant Bacteria in these infections. The resistance of Enterobacteriaceae to antibiotics is now a global concern. This study aims to reduce the risk of infections in the Maternity Ward of Bethesda Hospital. Twenty-four (24) samples were collected f...
Article
Full-text available
Objective: Mangifera indica Linn, Bridelia ferruginea Benth, and Alstonia boonei De Wild are three plants commonly used in the traditional treatment of urinary tract infections in Benin. This study sets out to assess the cytotoxic and teratogenic effects of extracts of these plants on Artemia salina larvae and hen embryos. Methods and results: T...
Article
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Background Vulvovaginal candidiasis is a widespread mycotic infection that affects a large proportion of women of childbearing age. Its management in traditional medicine is based on the use of medicinal plants. This study aimed to evaluate the antifungal activity of Ocimum gratissimum L . , Lantana camara L. and Pteleopsis suberosa Engl. & Diels u...
Article
Bats play a very important role in the transmission of zoonosis, including Salmonella. Salmonella are responsible for salmonellosis, which is a major public health concern. They are the cause of many hospitalizations and deaths worldwide. The objective of this study was to contribute to the im-provement of the control of zoonotic strains of Salmone...
Preprint
Antimicrobial resistance (AMR) is one of the greatest global threats to human health, but substantial gaps in AMR data exist in West African countries. To obtain in-depth data, we explored the presence of antimicrobial resistance genes (ARGs) in the hospital wastewaters (HWW) of nine hospitals in Benin and Burkina Faso and, for comparison, of four...
Article
Full-text available
Benin has attractive ethnobotanical potential with a vast diversity of medicinal plants widely used to treat human diseases. Urinary tract infections are among the diseases traditionally treated by medicinal plants. Mangifera indica, Bridelia ferruginea, Alstonia boonei, Morodora myristica, Xylopia aethiopica and Zanthoxylum zantoxyloides are six p...
Article
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Previous work stated that Khaya senegalensis, Anacardium ouest L., Pterocarpus erinaceus, Diospyros mespiliformis, Ocimum gratissimum, Manihot esculenta, Vernonia amygdalina Delile, and Daniellia oliveri have a great potential for the fight against infectious diarrhea. However, data on their antibacterial activity on strains of bacteria responsible...
Article
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Aims: This study aims to characterize of toxigenic Vibrio cholerae strains for improved cholera surveillance in Benin. Methodology: 304 diarrheal stool samples were collected from people with watery diarrhea of unknown etiology and vomiting during epidemics from 2016 to 2018 in Benin. Strains were isolated and then biochemical tests, serogrouping a...
Article
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Cochlospermum tinctorium Perrier is a medicinal plant used in several countries for the treatment of hepatitis. In Benin, different powders made from its rhizomes are sold in markets and used by traditional healers for several purposes. The objective of this study was to list the different forms and uses of Cochlospermum tinctorium-based recipes us...
Article
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From the Asteraceaes family, Tridax procumbens is a wild species frequently found in fields, meadows and roadsides. It is traditionally used to treat yellow fever, typhoid fever, high blood pressure and diabetes. In this work we used the hydro-ethanolic extract of the leaves and stems of the plant and also the fractions of this extract to determine...
Article
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The study aims to document the level of contamination of the aquatic ecosystem of the Cotonou-Lake Nokoué canal hydrographic complex by multidrug-resistant bacteria and their resistance genes. For this purpose, water samples were taken from several points of the complex and from the sediments at the depth of the lake. Samples of several species of...
Article
Full-text available
Objective: The emergence and increasing spread of resistance to antibiotics in uropathogenic Enterobacteriaceae is a huge public health problem and increase the morbidity and mortality. The objective of this study was to produce scientific data on the virulence and level of resistance of these bacteria in Benin. Results: This study was conducted on...
Article
Full-text available
Background The matter of antimicrobial resistance evokes the urgency to explore alternatives to the antibiotics traditionally used for microbial infections. This study aimed to elucidate the mechanism of action of the antibacterial effect of Khaya senegalensis liable for bacterial strains responsible for diarrheal infections. Results The data coll...
Article
Full-text available
Background: The matter of antimicrobial resistance evokes the urgency to explore alternatives to the antibiotics traditionally used for microbial infections. This study aimed to elucidate the mechanism of action of the antibacterial effect of Khaya senegalensis liable for bacterial strains responsible for diarrheal infections.Results: The data coll...
Article
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Ethnobotanical relevance: Many plants are widely used in traditional medicine across Africa. In Benin, practitioners of Beninese traditional medicine make use of diverse medicinal plants in the traditional management of various diseases including diarrhoea. Aim of the study: This study aimed at highlighting the ethnomedicinal uses of 17 plants in t...
Article
Full-text available
Background: The environment plays an important role in the dissemination of multidrug resistant bacteria, especially through the aquatic ecosystem, including hospital effluents, rivers, but also spring water and drinking water. This study aims to determine selected antimicrobial resistance genes in some aquatic matrices in southern Benin. Methods:...
Article
Full-text available
Background: The environment plays an important role in the dissemination of multidrug resistant bacteria, especially through the aquatic ecosystem, including hospital effluents, rivers, but also spring water and drinking water. This study aims to determine selected antimicrobial resistance genes in some aquatic matrices in southern Benin. Methods:...
Article
Full-text available
Background: The environment plays an important role in the dissemination of multidrug resistant bacteria, especially through the aquatic ecosystem, including hospital effluents, rivers, but also spring water and drinking water. This study aims to determine selected antimicrobial resistance genes in some aquatic matrices in southern Benin. Methods:...
Article
Full-text available
verview Stats Comments Citations References (31) Related research (10+) Share Save Share on Twitter Abstract and figures Background: The environment plays an important role in the dissemination of multidrug resistant bacteria, especially through the aquatic ecosystem, including hospital effluents, rivers, but also spring water and drinking w...
Article
Full-text available
Cholera is an epidemic disease and a real public health problem throughout the world, particularly in West Africa. This study provides a comprehensive overview of the pathogenicity, epidemiology and Vibrio cholerae strains's antibiotics resistance in West Africa. A literature review was conducted online in English using the keywords "Cholera", "Vib...
Article
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This study aims to carry out a bacteriological characterization and determine the resistance profile of Vibrio cholerae O1 strains isolated during the epidemiological season of 2020 in Benin. To achieve this goal, 43 diarrheal stool samples were analyzed. The samples were taken during the epidemic period of 2020. Bacteriological analyses consist...
Article
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The use of medicinal plants in traditional medicine is a common practice in developing countries. However, this unregulated or poorly rational use may present a dose-dependent risk of toxicity to humans. This study aimed to explore the phytochemical and toxicological characteristics of ten (10) plant species used in the traditional treatment of inf...
Article
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Enterobacteria are host bacteria found in the gut of all warm-blooded animals. Many of these can be found in poultry faeces and can cause zoonotic diseases. This study was aimed to characterize Enterobacteria other than Salmonella from faeces of poultry sold in local markets in southern Benin. Fifteen markets in three cities were selected for sampl...
Article
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Ethanol consumption is a risk factor of male infertility. The use of medicinal plants offers an alternative for the treatment of male infertility in developing countries. This study aimed to evaluate the Rourea coccinea effect on ethanol‐induced male infertility in Wistar rats. Twenty‐five (25) male Wistar rats were randomised into five groups of f...
Preprint
Full-text available
Background: The environment plays an important role in the dissemination of multidrug resistant bacteria, especially through the aquatic ecosystem, which is made up of liquid hospital effluents, rivers, but also spring water and drinking water. This study aims to determinate resistomes in some aquatic matrices in southern Benin. Methods: These samp...
Article
Full-text available
Gram-negative bacilli can spread from the environment and through food products. This study aimed to characterize ESBL production and virulence genes from multidrug-resistant Gram-negative bacilli isolated from specimen collected from the environment, kitchen, and food products. A total of 130 samples were collected at local markets in seven differ...
Book
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L’année 2020 a débuté par le grand coup de massue porté par la pandémie de COVID-19. L’impact a été important sur les activités scientifiques dans le monde, mais l’Unité a quand même tout mis en oeuvre pour répondre à son devoir d’institution au service du développement. Le bilan de l’année nous donne 35 publications scientifiques, la participation...
Article
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Medicinal plants are a precious heritage for humanity and especially for the majority of poor communities in developing countries who depend on them for primary health care and livelihoods. They are used in traditional practices against urinary tract infections without any scientific evidence for most of the species used. This work aims to have a s...
Article
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Euphorbia hirta, Citrus aurantifolia and Heterotis rotundifolia are plants of the traditional Beninese medicine. They are used in the treatment of several diseases, such as diarrheal infections, salmonellosis, malaria and others. This study aims to contribute to the scientific knowledge of these plants through their phytochemical screening as well...
Article
Full-text available
Antimicrobial resistance is a real public health problem. All over the world, it has a considerable impact in hospitals. The present study was conducted to ascertain the bacterial ecology in two hospitals in Benin as well as the resistance genes present in the recovered isolates. A total of 146 environmental and catheter samples were collected at t...