Victoria Louise Meah

Victoria Louise Meah
University of Alberta | UAlberta · Program for Pregnancy and Postpartum Health

PhD, BSc (Hons)

About

45
Publications
8,119
Reads
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1,877
Citations
Citations since 2017
41 Research Items
1869 Citations
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20172018201920202021202220230100200300400500600
20172018201920202021202220230100200300400500600
Education
January 2015 - June 2016
Cardiff Metropolitan University
Field of study
  • PgC Teaching in Higher Education
September 2012 - September 2016
Cardiff Metropolitan University
Field of study
  • Cardiovascular Adaptation to Pregnancy
September 2009 - July 2012
Cardiff Metropolitan University
Field of study
  • Sport and Exercise Science

Publications

Publications (45)
Article
Full-text available
Guidelines for physical activity during pregnancy have existed since 1985. Extensive literature in the subsequent forty years have conclusively demonstrated the safety and benefits of prenatal physical activity for individuals without contraindications. [1, 2] Most global guidelines include specific medical conditions where moderate to vigorous int...
Article
Full-text available
Purpose: Previous work suggests that endurance-trained athletes have superior pulmonary vasculature function as compared to untrained individuals, which may contribute to their greater maximal oxygen uptake ([Formula: see text]O2max). Inhaled nitric oxide (iNO) reduces pulmonary vascular resistance in healthy individuals, which could translate int...
Article
Full-text available
Introduction: Polycystic Ovary syndrome (PCOS) is a metabolic disorder associated with increased cardiovascular disease risk. Exercise is an effective treatment strategy to manage symptoms and reduce long-term health risk. High-intensity interval training (HIIT) has been suggested as a more efficient exercise mode in PCOS; however, it is not clear...
Article
The high-altitude maladaptation syndrome known as chronic mountain sickness (CMS) is characterized by polycythemia and is associated with proteinuria despite unaltered glomerular filtration rate. However, it remains unclear if indigenous highlanders with CMS have altered volume regulatory hormones. We assessed N-terminal pro-B-type natriuretic pept...
Article
Background Structural remodeling of the right ventricle (RV) is widely documented in athletes. However, functional adaptation, including RV pressure generation and systolic free-wall longitudinal mechanics, remains equivocal. This meta-analysis compared RV pressure and function in athletes and controls. Methods A systematic review of online databa...
Article
Full-text available
The health benefits of prenatal physical activity (PA) are established for singleton pregnancies. In contrast, individuals with multifetal pregnancies (twins, triplets or more) are recommended to restrict or cease PA. The objectives of the current study were to determine behaviors and barriers to PA in multifetal pregnancies. Between 29 May and 24...
Article
Pregnancy is recognized as a natural physiological stressor to the maternal cardiovascular system. Cardiovascular adaptation is markedly greater in twin compared to singleton pregnancy; however, these changes are sparsely documented in triplet pregnancy. The aim of this case series was to compare maternal cardiac function, cardioautonomic regulatio...
Article
Patients with mild chronic obstructive pulmonary disease (COPD) have an exaggerated ventilatory response to exercise, contributing to dyspnoea and exercise intolerance. Previous research in mild COPD has demonstrated an elevated ventilatory equivalent to CO2 production (V̇E/V̇CO2) during exercise, secondary to increased dead space ventilation. The...
Article
In conjunction with significant cardiovascular adaptation, changes in cardioautonomic balance, specifically greater sympathetic activation and vagal withdrawal, are considered normal adaptations to healthy singleton pregnancy. Cardiovascular adaptation to twin pregnancy is more profound than that of singleton pregnancies; however, the changes in ca...
Article
Purpose: Exercise guidelines recommend incorporating resistance exercise (RE) into a regular aerobic training program during pregnancy. Yet, few women do so due to uncertainties about the safety of prenatal RE, particularly regarding the Valsalva maneuver (VM). The aim of this study was to determine the acute cardiovascular responses to prenatal R...
Article
Purpose: The increased physiological demand of pregnancy results in profound adaptation of the maternal cardiovascular system, reflected by greater resting cardiac output and left ventricular (LV) deformation. Whether the increased resting demand alters acute cardiac responses to exercise in healthy pregnant women is not well understood. Methods:...
Article
Early acclimatization to high-altitude is characterized by various respiratory, hematological, and cardiovascular adaptations that serve to restore oxygen delivery to tissue. However, less is understood about renal function and the role of renal oxygen delivery (RDO2) during high-altitude acclimatization. We hypothesized that: 1) RDO2 would be redu...
Article
This study has identified that sympathetically mediated blood pressure regulation is reduced following ascent to high altitude. Additionally, we show that high-altitude Andean natives have reduced blood pressure responsiveness to sympathetic nervous activity (SNA) outflow compared with Nepalese Sherpa. However, basal sympathetic activity is inverse...
Article
Objectives: Despite extensive evidence demonstrating the benefits of prenatal physical activity (PA), inefficient knowledge translation may contribute to low rates of PA during pregnancy. This study aimed to examine the impact of the 2019 Canadian Guideline for Physical Activity throughout Pregnancy (hereafter Guideline) on knowledge transmission...
Article
Full-text available
During pregnancy, assessment of cardiac output (Q ̇), a fundamental measure of cardiovascular function, provides important insight into maternal adaptation. However, methods for dynamic Q ̇ measurement require validation. The purpose of this study was to estimate the agreement of Q ̇ measured by echocardiography and Modelflow® at rest and during su...
Article
Full-text available
Introduction: Depression and anxiety affect one in seven women during the perinatal period, and are associated with increased risk of preterm delivery, reduced mother-infant bonding, and delays in cognitive/emotional development of the infant. With this survey we aimed to rapidly assess the influence of the COVID-19 pandemic and subsequent physical...
Article
Background Clinical guidelines recommend pregnant women without contraindication engage in regular physical activity. This is based on extensive evidence demonstrating the safety and benefits of prenatal exercise. However, certain medical conditions or contraindications warrant a reduction, modification or cessation of activity due to potential hea...
Article
Introduction: Post-menopausal women have lower resting cardiac function than pre-menopausal women, but whether the menopause influences maximal cardiac output and hence exercise capacity is unclear. It is possible that pre- and post-menopausal women achieve similar improvements in maximal aerobic capacity (V[Combining Dot Above] O2max) and cardiac...
Article
New findings: What is the central question of this study? Herein, a methodological overview of our research team's (Global REACH) latest high altitude research expedition to Peru is provided. What is the main finding and its importance? The experimental objectives, expedition organization, measurements, and key cohort data are discussed. The selec...
Article
Full-text available
New findings: What is the central question of this study? Does chronic mountain sickness (CMS) alter sympathetic neural control and arterial baroreflex regulation of blood pressure in Andean (Quechua) highlanders? What is the main finding and its importance? Compared to healthy Andean highlanders, basal sympathetic vasomotor outflow is lower, baro...
Article
Full-text available
Key points: In an anaesthetized animal model, independent stimulation of baroreceptors in the pulmonary artery elicits reflex sympathoexcitation. In humans, pulmonary arterial pressure is positively related to basal MSNA under conditions where elevated pulmonary pressure is evident (e.g. high-altitude); however, a causal link is not established. U...
Article
Full-text available
Background: Ascent to altitude increases the prevalence of arrhythmogenesis in low-altitude dwelling populations (Lowlanders). High altitude populations (i.e., Nepalese Sherpa) may have arrhythmias resistant adaptations that prevent arrhythmogenesis at altitude, though this has not been documented in other High altitude groups, including those diag...
Article
Microneurography, a technique used to detect postganglionic sympathetic nerve traffic in humans, is increasingly used to further the understanding of autonomic regulation in health and disease. The technique involves the transcutaneous insertion of a microelectrode into a peripheral nerve, following which, a variety of adverse acute responses; afte...
Article
Objective To examine the relationships between prenatal physical activity and prenatal and postnatal urinary incontinence (UI). Design Systematic review with random effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study eligibility criteria Studies of all designs were included (except c...
Article
Full-text available
Objective We aimed to identify the relationship between maternal prenatal exercise and birth complications, and neonatal and childhood morphometric, metabolic and developmental outcomes. Design Systematic review with random-effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study eligibil...
Article
Full-text available
Objective To examine the influence of prenatal exercise on depression and anxiety during pregnancy and the postpartum period. Design Systematic review with random effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study eligibility criteria Studies of all designs were included (except cas...
Article
Objective: To perform a systematic review and meta-analysis to explore the relationship between prenatal exercise and glycaemic control. Design: Systematic review with random-effects meta-analysis and meta-regression. Data sources: Online databases were searched up to 6 January 2017. Study eligibility criteria: Studies of all designs were in...
Article
Objective Gestational diabetes mellitus (GDM), gestational hypertension (GH) and pre-eclampsia (PE) are associated with short and long-term health issues for mother and child; prevention of these complications is critically important. This study aimed to perform a systematic review and meta-analysis of the relationships between prenatal exercise an...
Article
Objective Gestational weight gain (GWG) has been identified as a critical modifier of maternal and fetal health. This systematic review and meta-analysis aimed to examine the relationship between prenatal exercise, GWG and postpartum weight retention (PPWR). Design Systematic review with random effects meta-analysis and meta-regression. Online dat...
Article
Introduction: Healthy pregnancy causes significant changes in maternal hemodynamics that lead to structural and functional adaptation of a woman's heart. Reductions in ejection fraction have been reported in healthy pregnancy; however, this measure of cardiac contractile function is over simplistic and insensitive to the underpinning hemodynamic l...
Article
Objective The purpose of this review was to investigate the relationship between prenatal exercise, and low back (LBP), pelvic girdle (PGP) and lumbopelvic (LBPP) pain. Design Systematic review with random effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study eligibility criteria Studi...
Article
Objective To perform a systematic review of the relationships between prenatal exercise and maternal harms including labour/delivery outcomes. Design Systematic review with random effects meta-analysis and meta-regression. Datasources Online databases were searched up to 6 January 2017. Study eligibility criteria Studies of all designs were incl...
Article
Objective To investigate the relationships between exercise and incidence of congenital anomalies and hyperthermia. Design Systematic review with random-effects meta-analysis . Data sources Online databases were searched from inception up to 6 January 2017. Study eligibility criteria Studies of all designs were eligible (except case studies and...
Article
Full-text available
Objective To perform a systematic review and meta-analysis examining the influence of acute and chronic prenatal exercise on fetal heart rate (FHR) and umbilical and uterine blood flow metrics. Design Systematic review with random-effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study e...
Article
Full-text available
Objective To perform a systematic review of the relationship between prenatal exercise and fetal or newborn death. Design Systematic review with random-effects meta-analysis and meta-regression. Data sources Online databases were searched up to 6 January 2017. Study eligibility criteria Studies of all designs were included (except case studies)...
Article
In the general population, functional haemodynamic testing, such as submaximal aerobic exercise, isometric handgrip, and the cold pressor test, has long been utilised to unmask abnormalities in cardiovascular function. During pregnancy, functional haemodynamic testing places additional demands on an already stressed maternal cardiovascular system....
Article
Full-text available
Objective: Cardiac output, a fundamental parameter of cardiovascular function, has consistently been shown to increase across healthy pregnancy; however, the time course and magnitude of adaptation remains equivocal within published literature. The aim of the present meta-analyses was to comprehensively describe the pattern of change in cardiac ou...
Article
Journal of Physiology Journal Club response to; Niu, Y., Herrera, E.A., Evans, R.D., & Giussani, D.A. (2013). Antioxidant treatment improves neonatal survival and prevents impaired cardiac function at adulthood following neonatal glucocorticoid therapy. J Physiol 591, 5083–5093.
Article
Full-text available
Healthy pregnancy is characterised by progressive physiological adaptation of the maternal cardiovascular (CV) system that facilitates optimal fetal development. The adaptations that constitute a healthy or normal progression are not always evident, and, in particular, CV adaptation to pregnancy is highly individualised. Some women develop pregnanc...

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