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Viacheslav Pauls

Viacheslav Pauls
Northern Trans-Ural State Agricultural University, Russia, Tyumen · Engineering-Technological Institute

PhD

About

29
Publications
13,926
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Introduction

Publications

Publications (29)
Article
Full-text available
The purpose of this paper is to study the redox status and biochemical parameters of T341P desminopathy in a heterozygous state. Most of the studied indicators of oxidative stress increase when approaching the middle course of T341P desminopathy. In particular, malondialdehyde and 8-OH-deoxyguanosine increase by 1.2 and 2 times, respectively, and t...
Article
The electrodiffusion processing is considered, which creates conditions for "upward diffusion" of alloying elements into the hardened surface. It has been found out that an increase in the microhardness of the surface of 40Mn2 steel was 1,18-1,51 times up to a depth of 250-350 μm with an increase in chromium concentration by 1,9 times. Pauls V.Yu.,...
Article
Full-text available
Introduction. Desminopathy is one of the varieties of myofibrillar myopathy that is caused by a mutation in the DES gene. To date, there is a lack of evidence regarding changes in immune status during the natural course of the disease. The aim of the study was to investigate the dynamics of immune status in myofibrillar myopathy with the T341P DES...
Conference Paper
Full-text available
From spring 2020 a series of foci of the SARS-CoV-2 coronavirus was registered at meat processing plants in North America and Europe. In this regard, the features of meat processing industries are analyzed and a review of the current sanitary rules is carried out. Information on the organization of the work of meat processing plants in the context...
Article
Full-text available
Nowadays the domestic market has a fairly wide range of equipment of Russian and foreign production equipment for washing plant materials. Unfortunately, most of the commercially available washers are characterized by high operating costs, high metal consumption and significant overall dimensions. The most common in the processing industries of the...
Article
Full-text available
Introduction: Desminopathy is a rare hereditary disease associated with a mutation in the DES gene, which is a type of myofibrillar myopathy. Damage to skeletal, cardiac, smooth muscles, as well as the diaphragm is possible with this disease. In clinical practice, desminopathy is a difficult diagnostic task. Purpose of the study. Study of the dynam...
Article
Full-text available
The hardening technologies currently known are not suitable for machining hollow parts with a working inner surface. This is due to the complex configuration of products, a significant length of internal cavities, low scattering ability of a number of electrolytes. The article provides information about the features of the developed method and inst...
Article
Full-text available
Composite materials based on copper and its alloys (bronze, brass) are finding more and more widespread use in tractor and combine construction. The current state of agricultural engineering requires the manufacture of parts for new resource-saving technologies. Powder metallurgy allows you to create materials and alloys with a combination of compo...
Conference Paper
Full-text available
The processes of electrodiffusion heat treatment (EDHT) of brass CuZn40Mn2Pb2 are investigated. The formation of a hardened layer with characteristic changes in the structural components as a result of EDHT with subsequent cooling in air has been established. Filatov A.S., Pauls V.Yu., Rozhkova T.V. ELECTRODIFFUSION HEAT TREATMENT OF BRASS CuZn40Mn...
Conference Paper
Full-text available
The processes of electrodiffusion heat treatment (EDHT) of CuSn8 bronze were investigated. It is established that the properties of the working surfaces of parts made of copper alloys can be significantly improved by EDHT. Pauls V.Y., Filatov A.S. ELECTRODIFFUSION THERMAL TREATMENT OF BRONZE CuSn8 / COLLECTION OF ARTICLES II OF THE ALL-RUSSIAN (NAT...
Data
Figure2. Device for massaging meat raw materials: 1 - frame, 2 - control panel, 3 - hollow drum, 4 - quadrangular pyramids, 5 - cover, 6 - left end face, 7 - right end face, 8 - shaft, 9 - axis, 10 - bearing supports, 11 - drive unit
Article
A parameter estimation of the thermal electrodiffusion treatment of hollow steel cylinders has been performed. An interrelation between hardening and a square relation of treated part and a cathode, as well as a distance between them were determined. Pauls V.Yu., Zhdanovich M.F. Parameter estimation of electrodiffusion hardening of hollow cylinder...
Article
Full-text available
The history of dermatology reminds a lot of attempts to transform the dense human skin samples into a liquid phase. A search for a method aimed to separate cellular substrate of the skin and to obtain a suspension for studying the cell phenotype profile was a basis of our long-term study, which resulted in a proprietary method for digital estimatio...
Conference Paper
Full-text available
The review of devices for massaging meat raw materials is given. The characteristic shortcomings of the equipment are revealed, further ways of improving the designs are indicated and new developments are presented. Pauls V.Yu. Improvement of structures of devices for massation of meat raw materials // Development of scientific, creative and innova...
Article
For the first time, information is presented on a patented invention - a skin cytomeimmunogram - a method that allows a single heterogeneous population of skin biopsy cells to obtain individual cell subpopulations and determine their phenotype. An example of a cytomeimmunogram with an analysis of the results is given, general recommendations are gi...
Article
Full-text available
Great importance for agricultural and general machinery is the restoration and strengthening of worn parts, which improves the efficiency and reliability of the subsequent operation. To extend the life of parts there are various ways to restore worn-out layer-coating, cladding or thermal coating. Adding a layer of reducing silicon dopant element or...
Patent
Method for determining the subpopulation composition of skin cells and obtaining the skin cytoimmunogram comprises sampling a skin biopsy specimen to a depth of 2 mm, homogenizing the tissue in a 0.9% aqueous solution of sodium chloride at a temperature of +23…+25°C, extracting the homogenate, filtering the homogenate through an inert filtering par...
Patent
Device for activation of reparative potencies of skin cells, containing containers, and also a top cover, characterized in that the containers are made of an opaque material in the form of truncated cones, inserted into each other, which On the lateral surface, in addition, have protruding annular beads with symmetrical chamfers for sealing, the up...
Article
Full-text available
The influence of process parameters electrodiffusion heat treatment (EDTO) on strengthening and improving the wear resistance of the surface layer. Modes are presented and the results of EDTO with subsequent normalization, and also features in the structure of the resulting low-alloy steels. Pauls V.Yu., Smolin N.I., Zhdanovich M.F., Skok M.A., Sta...
Article
Full-text available
Summary. The paper considers a new technology of electrodiffusion hardening of mower knives that provides wear resistance increase. Efficiency and reliability of further operation of cutter bars of agricultural machines are shown. Pauls V.Yu., Smolin N. I., Stavitskiy A.V., Skok M.A., Zhdanovich M.F. Innovative technology of electrodiffusion harden...
Book
The review of the current state and peculiarities of repair of the equipment of the processing branches of the agro-industrial complex is given. Technologies of restoration and hardening of parts of processing equipment, which are actively used at the enterprises of the agroindustrial complex, are considered. The operational characteristics of the...
Patent
SUBSTANCE: lower end of a processed part is sealed, an auxiliary electrode is placed into a part, and a salt melt is loaded to the level by 2.5-3.5 mm lower the upper end of the processed part. The part is heated up to 830-1190 K, anode polarisation is carried out with current having density from 0.1 to 25.0 A/dm2 in a salt melt, being an electroly...
Patent
SUBSTANCE: before building-up there is performed mechanical treatment of worn-out part to remove layer at depth sufficient for sealing microscopic fractures while applicating restoration layer. Sealing produces a restoration steel layer containing at least one of the following alloying elements, wt %: chromium 0.8-6.4, aluminium 0.5-1.5, and silico...
Patent
SUBSTANCE: invention relates to mechanical engineering field, chemical, metallurgical and other industries. Particularly it relates to anodic immunization of low-alloy steel. Method includes heating, anodic polarisation in salt melt and aftercooling with preliminary building of anodic polarisation curve for low-alloy steel in saline melt at the tem...
Article
The effect of an electric current on the diffusion of alloy-forming components and vacancies in alloy steels subjected to electrodiffusion heat treatment has been studied. The diffusion coefficients of chromium, silicon, and aluminum are shown to increase by one to three orders of magnitude as compared to the reported data.
Patent
The task of the useful model is to create a device that provides modern requirements for the quality of coagulum and the acceleration of the process of blood coagulation. The technical result consists in increasing the fraction of fine fractions of blood coagulum after treatment in the proposed device. The device for blood coagulation consists of a...
Patent
The invention relates to the field of metallurgy, in particular to methods for producing antifriction coatings and hardening parts of a cylinder-piston group of internal combustion engines, for example piston rings. The method includes heating, anodic polarization of the part in a salt melt with a current of 0.1-25.0 A / dm2 for 1.5-2.0 hours at th...
Patent
SUBSTANCE: apparatus has casing with heated water jacket, charging and discharge branch pipes and screw located eccentrically inside casing. Screw shaft is made hollow, with at least two rows of steam supply apertures. Said rows of steam supply apertures are arranged in helical paths parallel to and in equally spaced relation with respect to helica...

Questions

Questions (16)
Question
A patient with desminopathy survived Covid-19 six months ago without pneumonia, but with a temporary loss of smell and taste. After Covid-19, we note an accelerated progression of desminopathy, penetration accelerates, new muscles are quickly involved in the pathological process, muscle mass decreases, and heart function worsens. Perhaps the infection or its consequences are somehow connected with the mechanism of progression of desminopathy?
Question
To save life in desminopathy, can the body purposefully reduce muscle mass, for example, due to decreased heart function or for another reason?
It is known that when hypothermia, the body sacrifices limbs for survival. Is it possible with desminopathy a similar phenomenon?
Question
A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the blood.
Oddly enough, but all this is characteristic of infections, including viral ones. For example, it is known that if the hepatitis C virus is not treated, then death will occur in 20 years.
In the identified case of late onset desminopathy, muscle weakness manifests itself at the age of 30, and death occurs 20 years after the onset of the disease.
Could the desmin mutation in myofibrillar myopathy be caused by an infection?
Perhaps the infection contributes to the progression of desminopathy?
Question
A patient with hereditary desminopathy (mutation Thr341Pro DES in a heterozygous state) with disease progression has a significant decrease in taste. How can this fact be explained?
Question
In a patient with hereditary desminopathy (Thr341Pro DES mutation in a heterozygous state) with disease progression over the past 7 years, the level of residual nitrogen in the blood increased 1.5 times to 24.2 mmol / L (normal 14-28 mmol / L), and the level blood urea increased 1.24 times to 5.7 mmol / L (normal 2.5 - 8.32 mmol / L). Could this worsen the condition with desminopathy?

Network

Projects

Projects (4)
Project
Development of new and modernization of existing equipment of processing plants in order to increase productivity, reliability, ease of use, product quality, and reduce material consumption, operating costs.
Project
A cytomeimmunogram that promotes radiation from a general heterogeneous population of skin biopsy cells to obtain individual subpopulations of cells and determine their phenotype.
Project
A composition, structure, mechanical properties and corrosion resistance of alloy steels samples after electrodiffusion heat treatment are investigated.