Veronika Schöpf

Veronika Schöpf
Medical University of Vienna | MedUni Vienna · Department of Biomedical Imaging and Image-guided Therapy

About

172
Publications
50,669
Reads
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4,318
Citations
Additional affiliations
May 2019 - present
Medical University of Vienna
Position
  • Professor
October 2014 - June 2019
Karl-Franzens-Universität Graz
Position
  • Professor (Full)
October 2013 - September 2015
Medical University of Vienna
Position
  • Professor (Assistant)
Description
  • http://www.meduniwien.ac.at/user/veronika.schoepf/index.php/kontakt.html
Education
October 2017 - November 2019
TU Wien
Field of study
  • General Management
July 2008 - December 2015
Medical University of Vienna
Field of study
  • Neuroscience
July 2005 - July 2008
Ludwig-Maximilians-University of Munich
Field of study
  • Humanbiology

Publications

Publications (172)
Article
Full-text available
Olfactory function is a key sense for human well-being and health, with olfactory dysfunction having been linked to serious diseases. As the microbiome is involved in normal olfactory epithelium development, we explored the relationship between olfactory function (odor threshold, discrimination, identification) and nasal microbiome in 67 healthy vo...
Article
Contextual odors can serve as retrieval cues when applied during encoding and recall/recognition of information. To investigate the neuronal basis of these observations, we collected functional MRI data while participants (n=51) performed an encoding and recognition memory task during which odors (congruent: CO or incongruent: IO) were presented as...
Article
Full-text available
For the visual and auditory senses, an array of studies has reported on neuronal reorganization processes after sensory loss. In contrast to this, neuroplasticity has been investigated only scarcely after loss of the olfactory sense. The present review focuses on the current extent of literature on structural and functional neuroplasticity effects...
Article
Full-text available
The effects of sensory loss on central processing in various sensory systems have already been described. The olfactory system holds the special ability to be activated by a sensorimotor act, without the presentation of an odor. In this study, we investigated brain changes related to chronic peripheral smell loss. We included 11 anosmic patients (8...
Article
Full-text available
Recently, olfactory training has been introduced as a promising treatment for patients with olfactory dysfunction. However, less is known about the neuronal basis and the influence on functional networks of this training. Thus, we aimed to investigate the neuroplasticity of chemosensory perception through an olfactory training program in patients w...
Article
BACKGROUND: Childhood cerebellar pilocytic astrocytomas harbour excellent overall survival rates after surgical resection, but the patients may exhibit specific cognitive and behavioural problems emphasising our current understanding of the cerebellar role in cognition. Functional MRI has catalysed the mechanistic insights into brain functional sys...
Article
Full-text available
Background Childhood cerebellar pilocytic astrocytomas harbor excellent overall survival rates after surgical resection, but the patients may exhibit specific cognitive and behavioral problems. Functional MRI has catalyzed insights into brain functional systems and has already been linked with the neuropsychological performance. We aimed to exploit...
Article
Obesity has been associated with increased reward sensitivity to food stimuli, but a few studies have addressed this issue by using odors. This study investigated whether obesity is associated with increased liking and wanting of food odors and whether alexithymia, a psychological construct characterized by diminished affective abilities, contribut...
Article
Full-text available
Background Methane is an end product of microbial fermentation in the human gastrointestinal tract. This gas is solely produced by an archaeal subpopulation of the human microbiome. Increased methane production has been associated with abdominal pain, bloating, constipation, IBD, CRC or other conditions. Twenty percent of the (healthy) Western popu...
Article
Full-text available
Objective The purpose of our functional magnetic resonance imaging (fMRI) study was to examine brain activity using a “1-back” paradigm as working memory task in drug-naïve subjects with first episode schizophrenia before and after cognitive remediation training. Methods In this study 15 drug-naïve first episode subjects who met DSM-IV criteria fo...
Article
Full-text available
Introduction: Cigarette smoking is known to modulate brain metabolism and brain function. How the dynamics of these metabolic alterations influence the active performance of higher order cognitive tasks in smokers, compared to non-smokers, is still unclear. The present exploratory study sought to examine the impact of smoking on the "complete" met...
Preprint
Full-text available
Background Methane is an end product of microbial fermentation in the human gastrointestinal tract. This gas is solely produced by an archaeal subpopulation of the human microbiome. Increased methane production has been associated with abdominal pain, bloating, constipation, IBD, CRC or other conditions. Twenty percent of the (healthy) Western popu...
Article
Full-text available
p>This is a correction notice for article bjaa041 (DOI: https:// doi.org/10.1093/chemse/bjaa041), published 20 June 2020. An incorrect version of the caption to Figure 5 was mistakenly included in the published paper. An updated version is given below. Neither the data nor the paper's conclusions were affected by this correction. The authors sincer...
Preprint
Full-text available
Archaea are responsible for methane production in the human gastrointestinal tract. Twenty percent of the Western populations exhale substantial amounts of this gas. The underlying principle determining high or low methane emission and its effect on human health was still not sufficiently understood. In this study, we analysed the gastrointestinal...
Article
Full-text available
Purpose Using conventional magnetic resonance imaging (MRI) techniques, the imaging features of meningiomas and dural metastases overlap and a differentiation between these tumor entities therefore remains difficult, particularly in patients with a known primary neoplasm. The purpose of this study was to explore the potential role of normalized vas...
Article
Full-text available
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation and...
Preprint
Full-text available
Now published in Chemical Senses doi: 10.1093/chemse/bjaa041. Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, generally lacked quantitative measure...
Article
Full-text available
Temporal muscle thickness (TMT) was investigated as a novel surrogate marker on MRI examinations of the brain, to detect patients who may be at risk for sarcopenia. TMT was analyzed in a retrospective, normal collective cohort (n = 624), to establish standard reference values. These reference values were correlated with grip strength measurements a...
Article
Full-text available
Odors can increase memory performance when presented as context during both encoding and retrieval phases. Since information from different sensory modalities is integrated into a unified conceptual knowledge, we hypothesize that the social information from body odors and faces would be integrated during encoding. The integration of such social inf...
Article
Full-text available
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, and generally lacked quantitative measurements. Here, we report the development, implementation and...
Article
Full-text available
Due to their fundamentally different biology, archaea are consistently overlooked in conventional microbiome surveys. Using amplicon sequencing, we evaluated methodological set-ups to detect archaea in samples from five different body sites: respiratory tract (nasal cavity), digestive tract (mouth, appendix, and stool) and skin. With optimized prot...
Article
Full-text available
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization. Local microbial communities are shaped by the different characteristics of the specific location within the URT, but also by the interaction with both external and intrinsic factors, such as ageing, diseases, immune responses, olfactory function, and life...
Article
Full-text available
Purpose: Experimental investigations in rodents have contributed significantly to our current understanding of the potential importance of the gut microbiome and brain interactions for neurotransmitter expression, neurodevelopment, and behaviour. However, clinical evidence to support such interactions is still scarce. The present study used a doub...
Article
Background: Despite strongly overlapping patterns of clinical and histopathologic findings in primary and secondary progressive multiple sclerosis, differences concerning motor symptoms, central nervous system inflammation, atrophy, and demyelination that cannot be accounted for by lesion load alone remain to be elucidated. Purpose: To evaluate...
Article
The human brain networks at rest represent spontaneous activity that is highly correlated between different brain regions. Previous studies have shown that these resting-state networks are flexible and dynamic, and they can be affected by performance of different types of tasks. Moreover, it has been suggested that the re-activation of a task-relat...
Article
Full-text available
Objectives: This study aimed to assess the correlation of temporal muscle thickness (TMT), measured on routine cranial magnetic resonance (MR) images, with lumbar skeletal muscles obtained on computed tomography (CT) images in brain metastasis patients to establish a new parameter estimating skeletal muscle mass on brain MR images. Methods: We r...
Data
Detailed description of TMT, CSA and SMI values. (PDF)
Article
Full-text available
Nicotine addiction is known to modulate neurotransmission and alter the brain structure. The detrimental effect of nicotine is more prominent in females as compared to males. This study sought to examine the sex-specific influence of nicotine addiction on gamma amino butyric acid (GABA) and the white matter (WM) microstructure. Sixty healthy subjec...
Article
A growing body of evidence suggests that creativity is associated with functional connectivity across widespread neural networks, including regions associated with executive processes and cognitive control, along with regions linked to the default mode network (DMN) of the brain. This study investigated whether a three-week verbal divergent thinkin...
Article
Full-text available
Objectives: The purpose of this study was to evaluate the prognostic relevance of temporal muscle thickness (TMT) in melanoma patients with newly diagnosed brain metastases. Methods: TMT was retrospectively assessed in 146 melanoma patients with newly diagnosed brain metastases on cranial magnetic resonance images. Chart review was used to retri...
Preprint
Full-text available
Due to their fundamentally different biology, archaea are consistently overlooked in conventional 16S rRNA gene amplicon surveys. Herein, we evaluate different methodological set-ups to detect and quantify archaea signatures in human samples (nose, oral, appendix, stool, and skin) using amplicon sequencing and quantitative PCR. With our optimized p...
Article
Full-text available
Experimental manipulation of the gut microbiome was found to modify emotional and cognitive behavior, neurotransmitter expression and brain function in rodents, but corresponding human data remain scarce. The present double-blind, placebo-controlled randomised study aimed at investigating the effects of 4 weeks’ probiotic administration on behavior...
Article
Purpose Skin-sparing and nipple-sparing mastectomies (SSM; NSM) remove the breast’s fibroglandular tissue (FGT), thereby reducing breast cancer risk. The postoperative presence of residual FGT (RFGT) is associated with remaining cancer risk. This study evaluated the role of MRI in the quantitative assessment of RFGT and its impact on the estimation...
Article
Full-text available
Even though deficits in olfactory function affect a considerable part of the population, the neuronal basis of olfactory deficits remains scarcely investigated. To achieve a better understanding of how smell loss affects neural activation patterns and functional networks, we set out to investigate patients with olfactory dysfunction using functiona...
Article
Introduction: Individuals with unexplained smell loss constitute an at-risk population for the development of Parkinson's disease (PD). Currently, no specific MRI patterns are known for early PD diagnosis. In this study, we measured the fractional anisotropy (FA) in the substantia nigra (SN) in PD patients, in patients with idiopathic smell loss,...
Article
Full-text available
Purpose: Radial magnetic resonance imaging (MRI) is the most accurate diagnostic tool in assessing cam-type femoroacetabular impingement. Plain radiographs, however, are useful for the initial diagnosis in the daily practice and there is still debate regarding the optimal lateral view. The purpose of this study was to investigate the reliability o...
Article
Full-text available
BACKGROUND AND PURPOSE While it has been shown that treatment for cerebellar tumors has an impact on cognitive functions, the extent to which they shape distant neuronal pathways is still largely undescribed. Thus, the present neuroimaging study investigated different aspects of cognitive function and their neuronal correlates in patients after chi...
Article
Full-text available
While it has been shown that cerebellar tumor lesions have an impact on cognitive functions, the extent to which they shape distant neuronal pathways is still largely undescribed. Thus, the present neuroimaging study was designed to investigate different aspects of cognitive function and their neuronal correlates in patients after childhood cerebel...
Data
Procedure of the 0-back (working memory control) task. The 0-back task was presented in block design, including 6 baseline and 5 active blocks (30 seconds per block) with an overall duration of five and a half minutes. The subjects were instructed to press a button every time a pre-defined number (stimulus duration 1500 ms) was presented. Each acti...
Data
Analysis of task-related networks using GLM. (DOCX)
Data
Behavioral and demographic data of patients and controls. The data set contains the subject code, age, sex, group (0 = patient, 1 = control), IQ, time since surgery (OP_fMRI) and task accuracy and reaction times for the IC and WM tasks. (CSV)
Data
Component beta-weights of the WM task and 0-back control task. (CSV)
Data
Component beta-weights of the AL task. (CSV)
Data
GLM T-map (NIFTI format) for controls > patients for the AL task (see S1 Text). (NII)
Data
Detailed description of task parameters employed in the MRI setting. (DOCX)
Data
Component time courses of the IC task (subject order as in S1 Dataset, column ‘subj_code_al_ic’). (ZIP)
Data
Component time courses of the WM task and 0-back control task (subject order as in S1 Dataset, column ‘subj_code_wm’). (ZIP)
Data
GLM T-map (NIFTI format) for patients > controls for the IC task (see S1 Text). (NII)
Data
GLM T-map (NIFTI format) for patients > controls for the WM task (see S1 Text). (NII)
Data
Procedure of the AL (alertness) task. The task was presented in block design including 6 baseline and 5 active blocks (30 seconds per block) with an overall duration of five and a half minutes. During active blocks, targets (crosses) appeared at randomly varying intervals (ISI 2100–2300 ms) in the middle of the screen. Subjects were instructed to r...
Data
Procedure of the IC (incompatibility) task. The task was presented in block design including 6 baseline and 5 active blocks (30 seconds per block) with an overall duration of five and a half minutes. During active blocks, arrows pointing either to the left or the right were presented on the left or the right side of a fixation cross located in the...
Data
Procedure of the WM (working memory) task. The task was presented in block design including 6 baseline and 5 active blocks (30 seconds per block) with an overall duration of five and a half minutes. During the working memory (2-back) task, a randomized sequence of one-digit numbers was presented on the screen. During each active block, 7 numbers (s...
Data
Remaining number of components after each preselection step. (DOCX)
Data
Component beta-weights of the IC task. (CSV)
Data
Component time courses of the AL task (subject order as in S1 Dataset, column ‘subj_code_al_ic’). (ZIP)
Data
GLM T-map (NIFTI format) for controls > patients for the IC task (see S1 Text). (NII)
Data
GLM T-map (NIFTI format) for controls > patients for the WM task (see S1 Text). (NII)
Data
GLM T-map (NIFTI format) for patients > controls for the AL task (see S1 Text). (NII)
Article
Anosmia and hyposmia, the inability or decreased ability to smell, is estimated to afflict 3-20% of the population. Risk of olfactory dysfunction increases with old age and may also result from chronic sinonasal diseases, severe head trauma, and upper respiratory infections, or neurodegenerative diseases. These disorders impair the ability to sense...
Article
Full-text available
To assess all clinically relevant components of olfactory perception, examinations for olfactory sensitivity, discrimination, and identification are performed. Besides the standard perceptual test battery, episodic olfactory memory might offer additional information about olfactory abilities relative to these standard clinical tests. As both olfact...