Veronica Guadagni

Veronica Guadagni
The University of Calgary | HBI · Cumming School of Medicine, Department of Physiology and Pharmacology and Clinical neuroscience

PhD

About

28
Publications
19,215
Reads
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395
Citations
Introduction
Postdoctoral Fellow in the Laboratory of Human Cerebrovascular Physiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary. I am looking at the interplay between aerobic exercise, sleep quality (PSG, actigraphy and self-reports), genetic status and Alzheimer’s disease. During my PhD in cognitive neuroscience at the University of Calgary I investigated the relationship between sleep and emotional empathy. I have conducted a sleep deprivation study, a cross sectional study and a neuroimaging study using fMRI and task based functional connectivity (PPI) www.veronicaguadagni.com http://www.ucalgary.ca/poulin/staff/veronica-guadagni
Additional affiliations
June 2017 - present
The University of Calgary
Position
  • PostDoc Position
September 2012 - April 2017
The University of Calgary
Position
  • PhD Student
Education
September 2012 - April 2017
The University of Calgary
Field of study
  • Cognitive Neuroscience
September 2008 - December 2010
Università degli Studi dell'Aquila
Field of study
  • Neuroscience
September 2005 - October 2008
Università degli Studi dell'Aquila
Field of study
  • Psychobiology

Publications

Publications (28)
Article
Full-text available
Previous studies have shown that sleep loss has a detrimental effect on the ability of the individuals to process emotional information. In this study, we tested the hypothesis that this negative effect extends to the ability of experiencing emotions while observing other individuals, i.e. emotional empathy. To test this hypothesis, we assessed emo...
Article
Full-text available
The human ability to vicariously share someone else's emotions (i.e., emotional empathy) relies on an extended neural network including regions in the anterior cingulate and insular cortex. Here, we tested the hypothesis that good sleep quality is associated with increased activation in the brain areas underlying emotional empathy. To this aim, we...
Article
Full-text available
Background Sleep disturbances have been shown to be associated with the presence of the apolipoprotein (APOE) ɛ4 allele, the well-known genetic risk factor for late-onset sporadic Alzheimer’s disease (AD). Objective This study quantifies the effects of a six-month aerobic exercise intervention on objective and subjective sleep quality in middle-ag...
Article
Full-text available
To determine the relationship between sleep spindle characteristics (density, power and frequency), executive functioning and cognitive decline in older adults, we studied a convenience subsample of healthy middle‐aged and older participants of the Brain in Motion study. Participants underwent a single night of unattended in‐home polysomnography wi...
Article
Objective To test the hypothesis that aerobic exercise is associated with improvements in cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged and older adults (mean ± SD age 65.9 ± 6.4 years) in a supervised 6-month aerobic exercise intervention and assessed them before and after the intervention. Methods The s...
Article
Full-text available
Background Patients with unresectable recurrent rectal cancer (RRC) or colorectal cancer (CRC) with liver metastases, refractory to at least two lines of traditional systemic therapy, may receive third line intraarterial chemotherapy (IC) and targeted therapy (TT) using drugs selected by chemosensitivity and tumor gene expression analyses of liquid...
Article
Full-text available
Physical inactivity is a leading modifiable risk factor for cardiovascular and cerebrovascular disease, cognitive dysfunction, and global mortality. Regular exercise might mitigate age-related declines in cardiovascular and cerebrovascular function. In this study, we hypothesize that a 6-month aerobic exercise intervention will lead to a decrease i...
Article
Full-text available
Objective: To investigate the sex and gender differences in the impact of the isolation period implemented in response to the COVID-19 pandemic on individuals' sleep quality, empathy, and mood. Design: Data were collected between March 23 and June 7, 2020 on a sample of volunteers in the Canadian population. Six hundred and thirty-eight volunteers...
Article
Full-text available
Recent studies have stressed how patients with Obesity Hypoventilation Syndrome (OHS) are only a small portion of the OSA patients and how OSA is often undiagnosed in women. Low prevalence of OSA among females appears, in part, due to a greater lack of referral for polysomnographic sleep studies for women as compared to men. Moreover, there is evid...
Article
Background: We investigated altitude effects on different cognitive domains among perennial shift-workers at the Atacama Large Millimeter/submillimeter Array Observatory (5050 m), Chile. Materials and Methods: Twenty healthy male workers were recruited and assigned to either a moderate-altitude first (MAF group, Test 1: 2900 m and Test 2: 5050 m) o...
Article
Aging is associated with decline in white matter (WM) microstructure, decreased cognitive functioning, and increased risk of Alzheimer's disease and related dementias. Recent research has identified aerobic physical exercise as a promising intervention for increasing white matter microstructure in aging, with the aim of increasing cognitive abiliti...
Article
Full-text available
Purpose: To investigate the relative importance of isolated thoracic perfusion (ITP) in the multidisciplinary palliative treatment of progressive malignant pleural mesothelioma (MPM) patients. Methods: Fifty-two MPM patients with progressive disease after systemic chemotherapy with cisplatin and pemetrexed were submitted to 112 ITP using mitomyc...
Article
Full-text available
Introduction Sleep spindles are defining characteristics of NREM stage-2 sleep. Sleep spindle characteristics have been associated with memory consolidation and other cognitive functions, and have been used as marker of progressive cognitive decline in clinical populations. The objective of this study is to further explore the relationship between...
Article
Full-text available
Background: Empathy has been conceptualized as comprising a cognitive and an emotional component, the latter being further divided into direct and indirect aspects, which refer, respectively, to the explicit evaluation of the observer's feelings while attending someone in an emotional situation and to the physiological response of the observer. Em...
Article
Full-text available
Objective: Neurocognitive functions are affected by high altitude, however the altitude effects of acclimatization and repeated exposures are unclear. We investigated the effects of acute, subacute and repeated exposure to 5,050 m on cognition among altitude-naïve participants compared to control subjects tested at low altitude. Methods: Twenty-one...
Article
Full-text available
The ability to experience emotional empathy is critical for vicariously sharing the emotional state of others. This important empathic skill is significantly affected by sleep deprivation and poor sleep quality. Here, we provide the very first evidence that experienced paramedics have a significantly reduced emotional empathy as compared to non-par...
Article
Full-text available
Pelvic Melanoma relapse occurs in 15% of patients with loco regional metastases, and 25% of cases do not respond to new target-therapy and/or immunotherapy. Melphalan hypoxic pelvic perfusion may, therefore, be an option for these non-responsive patients. Overall median survival time (MST), stratified for variables, including BRAF V600E mutation an...
Article
Full-text available
Sleep loss is known to severely disturb individuals’ mood and emotion processing. Here, we tested the hypothesis that quality of sleep is predictive of individuals’ performance on a task evaluating emotional empathy. We tested 34 healthy undergraduate students [19males, mean (SD) age = 21.82 (3.26) years; mean (SD) education = 14.98 (1.91) years] r...
Article
Full-text available
Sleep is well known to have a significant impact on learning and memory. Specifically, studies adopting an experimentally induced sleep loss protocol in healthy individuals have provided evidence that the consolidation of spatial memories, as acquired through navigating and orienteering in spatial surroundings, is negatively affected by total sleep...
Poster
Full-text available
. Sleep loss is known to severely disturb individuals’ mood and emotion processing. Here, we tested the hypothesis that quality of sleep is predictive of individuals’ performance on a task evaluating emotional empathy. We tested 34 healthy undergraduate students [19 males, mean (SD) age = 21.82 (3.26) years; mean (SD) education = 14.98 (1.91) years...
Article
Full-text available
The ability to spatially orient is one of the most complex cognitive skills. It relies on the processing of different spatial information available in the environment, leading to the use of different cognitive strategies useful for orientation. The neural mechanisms underlying such a complex phenomenon include networks that require the proper funct...
Chapter
Wie bereits in ► Kap. 1 beschrieben, kann die Induktionschemotherapie Änderungen auslosen, welche die Erfolgsaussichten einer anschließenden Operation bzw. Strahlentherapie erhöhen. Die Beckenperfusion kann als Induktionschemotherapie für die Behandlung von Rektumkarzinomen vornehmlich bei Lokalrezidiven, aber auch bei bestimmten Patienten mit fort...

Questions

Question (1)
Question
I need some help in generating a field map from two gradient sequences  obtained at different eco times. I have a magnitude and a phase image for each TE. Particularly i need some help on how to do the scaling step so that the unwrapping would work. Please email me at veronicaguadagni@gmail.com if you have any insight.

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Projects (2)
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Archived project
Needs to be updated.