Vera Lehmann

Inselspital, Universitätsspital Bern · University Department of Endocrinology, Diabetes and Clinical Nutrition

BACKGROUND Hypoglycemia is a serious complication in diabetes, it impairs cognitive and psychomotor function, and is linked to driving mishaps. In-vehicle voice assistants (VAs) have been designed to proactively deliver a warning of hypoglycemia while driving. However, proactive VAs can cause driving impairments through startling. Hence, we complem...

OBJECTIVE To develop a noninvasive hypoglycemia detection approach using smartwatch data. RESEARCH DESIGN AND METHODS We prospectively collected data from two wrist-worn wearables (Garmin vivoactive 4S, Empatica E4) and continuous glucose monitoring values in adults with diabetes on insulin treatment. Using these data, we developed a machine learn...

Aims: Hypoglycemia is one of the most dangerous acute complications of diabetes mellitus and is associated with an increased risk of driving mishaps. Current approaches to detect hypoglycemia are limited by invasiveness, availability, costs, and technical restrictions. In this work, we developed and evaluated the concept of a non-invasive machine...

BACKGROUND Hypoglycemia is a frequent and acute complication in type-1 diabetes mellitus (T1DM) and is associated with a higher risk of car mishaps. Currently, hypoglycemia can be detected and signaled through flash glucose monitoring (FGM) or continuous glucose monitoring (CGM) devices. These devices, however, require manual and visual interaction...

Background Despite the increasing prevalence of postbariatric hypoglycemia (PBH), a late metabolic complication of bariatric surgery, our understanding of its diverse manifestation remains incomplete. Objectives To contrast parameters of glucose-insulin homeostasis in two distinct phenotypes of PBH (mild vs. moderate hypoglycemia) based on nadir p...

Background: To provide effective care for COVID-19 inpatients, clinical practitioners need systems that monitor patient health and subsequently allow for risk scoring. Existing approaches for risk scoring in COVID-19 patients focus primarily on intensive care units with specialized medical measurement devices, but not on hospital general wards. O...

Aim: To develop a non-invasive machine learning (ML) approach to detect hypoglycemia during real car driving based on driving (CAN) , and eye and head motion (EHM) data. Methods: We logged CAN and EHM data in 21 subjects with type 1 diabetes (18 male, 41 ± yrs, A1c 6.8 ± 0.7 % [51 ± 7 mmol/mol]) during driving in eu- (EU) and hypoglycemia (< 3.0 mm...

BACKGROUND To provide effective care for inpatients with COVID-19, clinical practitioners need systems that monitor patient health and subsequently allow for risk scoring. Existing approaches for risk scoring in patients with COVID-19 focus primarily on intensive care units (ICUs) with specialized medical measurement devices but not on hospital gen...

The cover image is based on the Brief Report The impact of postbariatric hypoglycaemia on driving performance: A randomized, single‐blind, two‐period, crossover study in a driving simulator by Vera Lehmann et al., https://doi.org/10.1111/dom.14456.

Postbariatric hypoglycemia (PBH) is an increasingly recognized complication of bariatric surgery, but its effect on daily functioning remains unclear. In this randomized single‐blind crossover trial we assessed driving performance in patients with PBH. Ten active drivers with PBH (8 females, age 38.2 ± 14.7 years, BMI 27.2 ± 4.6 kg/m2) received 75...

Aim: To non-invasively detect hypoglycemia in individuals with type 1 diabetes (T1D) based on gaze behavior while driving. Methods: Controlled hypoglycemia was induced in 19 individuals (12 males, age 32 ± 7.1 yrs) with T1D (HbA1c 7.1 ± 0.6% [54 ± 6 mmol/mol]) using an adapted hypoglycemic clamp protocol. Gaze and blood glucose (BG) data were gath...

Objective: To assess the association between daily carbohydrate (CHO) intake and glycemic control in adult hybrid closed-loop (HCL) users with type 1 diabetes (T1D). Research design and methods: Mean individual daily CHO intake (MIDC) and relative deviation from MIDC (≤80% low; 81-120% medium, >120% high CHO consumption) were compared with param...

Background White coat adherence (WCA) is defined as an increased adherence to treatment regimens directly before a visit with a healthcare provider. Little is known on the effect of WCA on glucose control in adult patients with diabetes mellitus. Methods The present study is based on 618 CGM-observations of 276 patients with diabetes treated betwe...

Background Migraine with aura (MwA) in pediatric patients is clinically frequent. Clinically complex symptoms need to be differentiated to exclude mimicking conditions. Purpose We hypothesize that MwA in children induces abnormalities readily visible in perfusion time to peak (TTP) maps as well as non-enhanced susceptibility weighted magnetic reso...

Rigorous blood glucose management is vital for individualswith diabetes to prevent states of too low blood glucose (hypoglycemia). While there are continuous glucose monitors available, they are expensive and not available for many patients. Related work suggests a correlation between the blood glucose level and physiological measures, such as hear...

The reactions of the human body to physical exercise, psychophysiological stress and heart diseases are reflected in heart rate variability (HRV). Thus, continuous monitoring of HRV can contribute to determining and predicting issues in well-being and mental health. HRV can be measured in everyday life by consumer wearable devices such as smartwatc...

The reactions of the human body to physical exercise, psychophysiological stress and heart diseases are reflected in heart rate variability (HRV). Thus, continuous monitoring of HRV can contribute to determining and predicting issues in well-being and mental health. HRV can be measured in everyday life by consumer wearable devices such as smartwatc...

Objectives Current recommendations for the measurement of tumor size in glioblastoma continue to employ manually measured 2D product diameters of enhancing tumor. To overcome the rater dependent variability, this study aimed to evaluate the potential of automated 2D tumor analysis (ATA) compared to highly experienced rater teams in the workup of pr...