Venkatraman Rajkumar

• MBBS;DNB;Diplomate American Boards Internal medicine, Geriatric medicine, Endocrinology,Diabetes & Metabolism
• Senior Consultant at Banting clinic

Erythrasma is a common superficial cutaneous bacterial infection caused by Corynebacterium minutissimum, a normal inhabitant of the skin surface. Under favourable conditions, the organism invades the stratum corneum, where it multiplies and produces clinically evident lesions. Increasing age, excessive sweating, diabetes mellitus, obesity, overcrow...

Primary hypothyroidism is a frequent presentation in primary care, and is treated with levothyroxine sodium tablets once daily in the morning in the fasting state. With an adequate dose, the goal is to achieve a thyroid stimulating hormone in the normal range in 6–8 weeks. Medications, foods, and gastrointestinal conditions can interfere with the a...

Background: Travel has become an integral part of life, whether for business, pleasure, sport, or pilgrimage. The increasing number of patients with diabetes mellitus translates to a greater number of travelers with this condition. Primary care physicians have little knowledge to guide patients with diabetes planning travel. Summary: A structured p...

Skeletal involvement is a frequent site of extrapulmonary tuberculosis, but an isolated disease of the ribs is rare. This case report studied an adult immunocompetent male patient who presented with constitutional symptoms, pain and point tenderness in two ribs. The diagnosis of rib tuberculosis was delayed due to earlier providers not recognizing...

Metabolic syndrome is a cluster of health conditions linked to increased cardiovascular disease. It is found worldwide in increasing proportions due to the modern lifestyle. The increase is visceral fat leads to secretion of harmful proinflammatory cytokines that have deleterious effects on various tissues, chiefly the heart and vasculature. Rheuma...

PMID 33085417 Lysosomal storage diseases (LSDs) are inborn errors of metabolism characterized by the accumulation of substrates in excess in various organs' cells due to the defective functioning of lysosomes. They cause dysfunction of those organs where they accumulate and contribute to great morbidity and mortality. Although rare individually, t...

Heavy metals(HMs) are defined differently by different people. In health parlance, they are naturally occurring substances that accumulate and cause damage to the environment and living beings, including humans. They also include substances known as semimetals or metalloids that can have the same deleterious effects. Humans are exposed to HMs thro...

The prevalence of vitamin D deficiency is ubiquitous. Severe disease can present very dramatically and can be misleading to the treating physician, resulting in mismanagement. A high index of suspicion in vulnerable patients should help circumvent this problem, including a thorough history and physical examination to lead the clinician in the right...

Diabetes mellitus (DM) is a disease spectrum ranging from classic insulinopenic type 1 diabetes (T1DM) at one end to classic insulin-resistant type 2 diabetes (T2DM) at the other. Latent autoimmune diabetes of adults (LADA) is a form of DM with features of both T1DM and T2DM and has therefore been termed Type 1.5 DM. In Japan, the synonym used is s...

Normocalcemic primary hyperparathyroidism (nPHPT) is a new phenotype of sporadic primary hyperparathyroidism where elevated PTH is the result of autonomous hypersecretion of one or more parathyroid glands, and serum calcium(Ca) is consistently normal. In normocalcemic secondary hyperparathyroidism (nSHPT), the PTH elevation is a reaction to a low...

Familial short stature (FSS) is a condition in which the final adult height achieved is less than the third percentile for the patient's age, gender, and population. Nevertheless, it is consistent with parental height in the absence of nutritional, hormonal, acquired, genetic, and iatrogenic causes. It is considered one of the most common causes of...

Hypoaldosteronism (HA) is a condition marked by decreased synthesis or diminished release of aldosterone (ALD) from the zona glomerulosa of the adrenal glands, or resistance to its action on target tissues. In conditions of resistance, aldosterone levels are often elevated and termed pseudo-hypoaldosteronism. Recent advances have unraveled the mec...

Muscle infaction is a rare complication in patients with diabetes mellitus, probably because of the rich vascular supply of this tissue. We describe a patient with type 1 diabetes who had infarction of the muscles in her right thigh. We report, for the first time, that the patient, in addition to an advanced microvascular disease in the muscle, had...

We investigated the effects of 17β-estradiol (βE2), α-estradiol (αE2), and progesterone (P) on baseline and vasopressin (AVP)-induced [Ca2+]i in human platelets obtained from healthy male and female volunteers. Platelets were treated with βE2, αE2, P, or ethanol vehicle for 30 min at 37°C. In males, both βE2 and P at 10−5mol/L reduced the AVPinduce...